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Aliases for TMEM60 Gene

Aliases for TMEM60 Gene

  • Transmembrane Protein 60 2 3
  • C7orf35 3 4
  • Chromosome 7 Open Reading Frame 35 2
  • DC32 3

External Ids for TMEM60 Gene

Previous HGNC Symbols for TMEM60 Gene

  • C7orf35

Previous GeneCards Identifiers for TMEM60 Gene

  • GC07M077068
  • GC07M077260
  • GC07M077423
  • GC07M072026

Summaries for TMEM60 Gene

GeneCards Summary for TMEM60 Gene

TMEM60 is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM60 Gene

Genomics for TMEM60 Gene

Regulatory Elements for TMEM60 Gene

Genomic Location for TMEM60 Gene

Start:
77,793,728 bp from pter
End:
77,798,580 bp from pter
Size:
4,853 bases
Orientation:
Minus strand

Genomic View for TMEM60 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMEM60 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM60 Gene

Proteins for TMEM60 Gene

  • Protein details for TMEM60 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H2L4-TMM60_HUMAN
    Recommended name:
    Transmembrane protein 60
    Protein Accession:
    Q9H2L4
    Secondary Accessions:
    • A4D1C3
    • Q86UM0

    Protein attributes for TMEM60 Gene

    Size:
    133 amino acids
    Molecular mass:
    15500 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH65930.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for TMEM60 Gene

Proteomics data for TMEM60 Gene at MOPED

Post-translational modifications for TMEM60 Gene

No Post-translational modifications

Other Protein References for TMEM60 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TMEM60 Gene

Domains for TMEM60 Gene

Protein Domains for TMEM60 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TMEM60 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TMEM60: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TMEM60 Gene

Function for TMEM60 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TMEM60 Gene

Localization for TMEM60 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM60 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TMEM60 Gene COMPARTMENTS Subcellular localization image for TMEM60 gene
Compartment Confidence
extracellular 2
plasma membrane 2
endoplasmic reticulum 1

Gene Ontology (GO) - Cellular Components for TMEM60 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM60: view

Pathways for TMEM60 Gene

SuperPathways for TMEM60 Gene

No Data Available

Interacting Proteins for TMEM60 Gene

Gene Ontology (GO) - Biological Process for TMEM60 Gene

None

No data available for Pathways by source for TMEM60 Gene

Transcripts for TMEM60 Gene

mRNA/cDNA for TMEM60 Gene

(121) Selected AceView cDNA sequences:
(3) Additional mRNA sequences :
(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TMEM60 Gene

Transmembrane protein 60:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM60 Gene

No ASD Table

Relevant External Links for TMEM60 Gene

GeneLoc Exon Structure for
TMEM60
ECgene alternative splicing isoforms for
TMEM60

Expression for TMEM60 Gene

mRNA expression in normal human tissues for TMEM60 Gene

SOURCE GeneReport for Unigene cluster for TMEM60 Gene Hs.19025

genes like me logo Genes that share expressions with TMEM60: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for TMEM60 Gene

Orthologs for TMEM60 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TMEM60 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TMEM60 35
  • 99.75 (n)
  • 100 (a)
TMEM60 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia LOC100295750 35
  • 96.74 (n)
  • 98.5 (a)
TMEM60 36
  • 98 (a)
OneToMany
TMEM60 36
  • 98 (a)
OneToMany
dog
(Canis familiaris)
Mammalia TMEM60 35
  • 96.49 (n)
  • 98.5 (a)
TMEM60 36
  • 98 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tmem60 35
  • 94.74 (n)
  • 99.25 (a)
Tmem60 16
Tmem60 36
  • 99 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia TMEM60 36
  • 88 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia TMEM60 36
  • 87 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Tmem60 35
  • 92.48 (n)
  • 97.74 (a)
chicken
(Gallus gallus)
Aves TMEM60 35
  • 81.82 (n)
  • 90.15 (a)
TMEM60 36
  • 89 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia TMEM60 36
  • 84 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia tmem60 35
  • 76.77 (n)
  • 83.33 (a)
zebrafish
(Danio rerio)
Actinopterygii zgc:91811 35
  • 67.17 (n)
  • 72.93 (a)
Species with no ortholog for TMEM60:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TMEM60 Gene

ENSEMBL:
Gene Tree for TMEM60 (if available)
TreeFam:
Gene Tree for TMEM60 (if available)

Paralogs for TMEM60 Gene

No data available for Paralogs for TMEM60 Gene

Variants for TMEM60 Gene

Sequence variations from dbSNP and Humsavar for TMEM60 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type MAF
rs7953 -- 77,794,257(-) ATATT(C/T)ATTCC reference, synonymous-codon
rs15962 -- 77,794,311(-) TTGAT(C/T)ATGTT reference, synonymous-codon
rs1045463 -- 77,793,835(-) AAACA(A/G)GATTG utr-variant-3-prime
rs6955067 -- 77,795,673(+) TTCCT(C/T)TTAAC intron-variant
rs6973656 -- 77,793,266(+) CCTTC(A/G)TAATT downstream-variant-500B

Relevant External Links for TMEM60 Gene

HapMap Linkage Disequilibrium report
TMEM60

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for TMEM60 Gene

Disorders for TMEM60 Gene

Relevant External Links for TMEM60

Genetic Association Database (GAD)
TMEM60
Human Genome Epidemiology (HuGE) Navigator
TMEM60
genes like me logo Genes that share disorders with TMEM60: view

No data available for UniProtKB/Swiss-Prot for TMEM60 Gene

Publications for TMEM60 Gene

  1. Human chromosome 7: DNA sequence and biology. (PMID: 12690205) Scherer S.W. … Tsui L.-C. (Science 2003) 3 4
  2. The DNA sequence of human chromosome 7. (PMID: 12853948) Hillier L.W. … Wilson R.K. (Nature 2003) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. New loci associated with kidney function and chronic kidney disease. (PMID: 20383146) KAPttgen A. … Fox C.S. (Nat. Genet. 2010) 3 48
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for TMEM60 Gene

Sources for TMEM60 Gene

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