Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



TMEM57 Gene

protein-coding   GIFtS: 47
GCID: GC01P025758

Transmembrane Protein 57

  Try our

disease database 

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Transmembrane Protein 571 2 3
MACOILIN2
macoilin2
FLJ107475

External Ids:    HGNC: 255721   Entrez Gene: 552192   Ensembl: ENSG000002041787   OMIM: 6103015   UniProtKB: Q8N5G23   

Export aliases for TMEM57 gene to outside databases

Previous GC identifers: GC01P025503 GC01P025629 GC01P024014


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for TMEM57 Gene:
TMEM57 (transmembrane protein 57) is a protein-coding gene.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NT_032977.10  NC_018912.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the TMEM57 gene promoter:
         CREB   AREB6   Pax-4a   NF-Y   CBF(2)   C/EBPalpha   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for TMEM57

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TMEM57


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p36.11|1p36.11   Ensembl cytogenetic band:  1p36.11   HGNC cytogenetic band: 1p36.11

TMEM57 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMEM57 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P025758:  view genomic region     (about GC identifiers)

Start:
25,757,388 bp from pter      End:
25,826,700 bp from pter
Size:
69,313 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: MACOI_HUMAN, Q8N5G2 (See protein sequence)
Recommended Name: Macoilin  
Size: 664 amino acids; 76178 Da
Secondary accessions: B1AK00 Q2TLX5 Q2TLX6 Q9NVG6
Alternative splicing: 3 isoforms:  Q8N5G2-1   Q8N5G2-2   Q8N5G2-3   

Explore the universe of human proteins at neXtProt for TMEM57: NX_Q8N5G2

Explore proteomics data for TMEM57 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys242, Lys296, Lys365, Lys438, Lys579
  • Glycosylation2 at Asn324, Asn340, Asn452, Asn655
  • Modification sites at PhosphoSitePlus

  • See TMEM57 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001269493.1  NP_060672.2  

    ENSEMBL proteins: 
     ENSP00000363463   ENSP00000382668   ENSP00000382666  

    TMEM57 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for TMEM57
    OriGene Protein Over-expression Lysate for TMEM57
    OriGene MassSpec for TMEM57
    OriGene Custom Protein Services for TMEM57
    GenScript Custom Purified and Recombinant Proteins Services for TMEM57
    Novus Biologicals TMEM57 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TMEM57

     
    Search eBioscience for Proteins for TMEM57 

    TMEM57 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for TMEM57
    Novus Biologicals TMEM57 Antibodies
    Abcam antibodies for TMEM57
    Cloud-Clone Corp. Antibodies for TMEM57
    ThermoFisher Antibodies for TMEM57
    LSBio Antibodies in human, mouse, rat for TMEM57

    TMEM57 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for TMEM57
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for TMEM57
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for TMEM57
    Cloud-Clone Corp. CLIAs for TMEM57
    Search eBioscience for ELISAs for TMEM57 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    1 InterPro protein domain:
     IPR019130 Macoilin

    Graphical View of Domain Structure for InterPro Entry Q8N5G2

    ProtoNet protein and cluster: Q8N5G2

    UniProtKB/Swiss-Prot: MACOI_HUMAN, Q8N5G2
    Similarity: Belongs to the macoilin family


    Find genes that share domains with TMEM57           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
         
    Find genes that share ontologies with TMEM57           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TMEM57
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TMEM57

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TMEM57
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TMEM57

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat TMEM57 using miScript Target Protectors
    8 qRT-PCR Assays for microRNAs that regulate TMEM57:
    hsa-miR-548p hsa-miR-4307 hsa-miR-1294 hsa-miR-507 hsa-miR-4316 hsa-miR-33a* hsa-miR-802 hsa-miR-3714
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for TMEM57
    Predesigned siRNA for gene silencing in human, mouse, rat TMEM57

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for TMEM57

    Clone
    Products:
         
    OriGene clones in human, mouse for TMEM57 (see all 7)
    OriGene ORF clones in mouse, rat for TMEM57
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TMEM57 (NM_018202)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM57
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM57

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for TMEM57
    Browse ESI BIO Cell Lines and PureStem Progenitors for TMEM57 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM57


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    MACOI_HUMAN, Q8N5G2: Nucleus membrane; Multi-pass membrane protein (By similarity). Cell projection, axon (By
    similarity). Note=Detected in the nucleus membrane of non-neuronal cells and in axonal outgrowths of neuronal
    cells (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    plasma membrane3
    golgi apparatus2
    cytosol1
    endoplasmic reticulum1

    Gene Ontology (GO): Selected cellular component terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ISS12459264
    GO:0016021integral component of membrane IEA--
    GO:0030424axon IEA--
    GO:0031965nuclear membrane ISS15255972
    GO:0043005neuron projection ----

    Find genes that share ontologies with TMEM57           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Pathway & Disease-focused RT2 Profiler PCR Arrays including TMEM57: 
              Necrosis in human mouse rat
              Molecular Toxicology PathwayFinder 384HT in human mouse rat
              Cell Death PathwayFinder in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for TMEM57

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    Selected Interacting proteins for TMEM57 (Q8N5G22, 3 ENSP000003634634) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SMAD9O151982, 3MINT-62095 I2D: score=3 
    ENSG00000206289P287023I2D: score=1 
    ENSG00000227322P287023I2D: score=1 
    ENSG00000228333P287023I2D: score=1 
    ENSG00000231321P287023I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007420brain development IEA--
    GO:0008150biological_process ND--

    Find genes that share ontologies with TMEM57           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TMEM57 (MACOI)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for TMEM57 gene (2 alternative transcripts): 
    NM_001282564.1  NM_018202.5  

    Unigene Cluster for TMEM57:

    Transmembrane protein 57
    Hs.189782  [show with all ESTs]
    Unigene Representative Sequence: NM_018202
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000374343(uc009vrt.2 uc001bkk.3) ENST00000470035 ENST00000399766(uc009vru.3)
    ENST00000399763(uc009vrv.3)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat TMEM57 using miScript Target Protectors
    8 qRT-PCR Assays for microRNAs that regulate TMEM57:
    hsa-miR-548p hsa-miR-4307 hsa-miR-1294 hsa-miR-507 hsa-miR-4316 hsa-miR-33a* hsa-miR-802 hsa-miR-3714
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for TMEM57
    Predesigned siRNA for gene silencing in human, mouse, rat TMEM57
    Clone
    Products:
         
    OriGene clones in human, mouse for TMEM57 (see all 7)
    OriGene ORF clones in mouse, rat for TMEM57
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TMEM57 (NM_018202)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM57
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM57
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for TMEM57
    OriGene qSTAR qPCR primer pairs in human, mouse for TMEM57
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMEM57
      QuantiTect SYBR Green Assays in human, mouse, rat TMEM57
      QuantiFast Probe-based Assays in human, mouse, rat TMEM57

    Additional mRNA sequence: 

    AK001609.1 AK311472.1 AY845015.1 AY845035.1 AY845036.1 BC007687.1 BC020801.1 BC032427.1 

    9 DOTS entries:

    DT.213218  DT.101544  DT.97846089  DT.92459454  DT.92459458  DT.95242268  DT.97846087  DT.40130016 
    DT.91836134 

    8 AceView cDNA sequences:

    BM786697 BM837961 AU130984 AL560159 BC007687 BE795477 BI918282 AK001609 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    TMEM57 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAAAATTGTC
    TMEM57 Expression
    About this image


    TMEM57 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Eye (Sensory Organs)
             Retina
    TMEM57 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TMEM57 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.189782
        Pathway & Disease-focused RT2 Profiler PCR Arrays including TMEM57: 
              Necrosis in human mouse rat
              Molecular Toxicology PathwayFinder 384HT in human mouse rat
              Cell Death PathwayFinder in human mouse rat

    Primer
    Products:
    OriGene qPCR primer pairs and template standards for TMEM57
    OriGene qSTAR qPCR primer pairs in human, mouse for TMEM57
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMEM57
    QuantiTect SYBR Green Assays in human, mouse, rat TMEM57
    QuantiFast Probe-based Assays in human, mouse, rat TMEM57
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM57

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals.

    Orthologs for TMEM57 gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tmem571 , 5 transmembrane protein 571, 5 92.02(n)1
    99.25(a)1
      4 (67.11 cM)5
    661461  NM_025382.61  NP_079658.21 
     1348027595 
    chicken
    (Gallus gallus)
    Aves TMEM571 transmembrane protein 57 84.59(n)
    94.41(a)
      419590  NM_001030895.2  NP_001026066.2 
    lizard
    (Anolis carolinensis)
    Reptilia TMEM576
    transmembrane protein 57
    95(a)
    1 ↔ 1
    GL343703.1(138378-173467)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.100822 Xenopus laevis transcribed sequence with strong similarity more 83.93(n)    BQ732351.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc566202 hypothetical protein MGC56620 81.74(n)   393289  BC051623.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG303891 CG30389 51.5(n)
    48.26(a)
      37410  NM_001274187.1  NP_001261116.1 
    worm
    (Caenorhabditis elegans)
    Secernentea maco-11 maco-1 45.82(n)
    31.55(a)
      183963  NM_059501.4  NP_491902.4 


    ENSEMBL Gene Tree for TMEM57 (if available)
    TreeFam Gene Tree for TMEM57 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for TMEM57 (see all 1285)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs773978981,2
    C,F--25755660(+) CCAGAG/AAGAGT 1 -- us2k11Minor allele frequency- A:0.02NA 120
    rs1877309691,2
    --25755825(+) TTTTTA/GGTAGA 1 -- us2k10--------
    rs1925801431,2
    --25755866(+) TCTCCA/GATCTC 1 -- us2k10--------
    rs607712011,2
    --25755921(+) TTACAA/GGCGTG 1 -- us2k10--------
    rs1394855831,2
    --25755991(+) CCATTG/TTCGTT 1 -- us2k10--------
    rs1842980151,2
    --25756037(+) TTCTGC/TAATAT 1 -- us2k10--------
    rs762620261,2
    C--25756122(+) TAGTAA/TGACTA 1 -- us2k10--------
    rs781479551,2
    C--25756123(+) AGTATG/TACTAC 1 -- us2k10--------
    rs801495131,2
    C--25756124(+) GTATGA/CCTACT 1 -- us2k10--------
    rs1892984001,2
    --25756185(+) CATAGA/GGGAAA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for TMEM57 (25757388 - 25826700 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 7 variations for TMEM57:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2570786CNV Deletion19546169
    nsv870664CNV Loss21882294
    nsv870937CNV Loss21882294
    nsv870470CNV Gain21882294
    nsv834480CNV Gain17160897
    nsv834469CNV Gain+Loss17160897
    nsv9768CNV Gain+Loss18304495

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TMEM57
    DNA2.0 Custom Variant and Variant Library Synthesis for TMEM57

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 610301    OMIM disorders: --


    Find genes that share disorders with TMEM57           About GenesLikeMe

    Genetic Association Database (GAD): TMEM57
    Human Genome Epidemiology (HuGE) Navigator: TMEM57 (4 documents)

    Export disorders for TMEM57 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for TMEM57 gene, integrated from 10 sources (see all 21):
    (articles sorted by number of sources associating them with TMEM57)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Complement receptor 1 gene variants are associated with erythrocyte sedimentation rate. (PubMed id 21700265)1, 4 Kullo I.J....Chute C.G. (Am. J. Hum. Genet. 2011)
    2. Biological, clinical and population relevance of 95 loci for blood lipids. (PubMed id 20686565)1, 4 Teslovich T.M....Kathiresan S. (Nature 2010)
    3. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    4. Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. (PubMed id 19060911)1, 4 Aulchenko Y.S....Peltonen L. (Nat. Genet. 2009)
    5. Identification of a novel brain-specific and Reelin-regulated gene that encodes a protein colocalized with synapsin. (PubMed id 15255972)1, 3 Kuvbachieva A....Simonneau M. (Eur. J. Neurosci. 2004)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    8. Entire sequence of a mouse chromosomal segment containing the gene Rhced and a comparative analysis of the homologous human sequence. (PubMed id 12459264)1, 3 Kumada M....Kajii E. (Gene 2002)
    9. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    10. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 55219 HGNC: 25572 AceView: FLJ10747 Ensembl:ENSG00000204178 euGenes: HUgn55219
    ECgene: TMEM57 H-InvDB: TMEM57

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for TMEM57 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for TMEM57 gene:
    Search GeneIP for patents involving TMEM57

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for TMEM57  
     OriGene qPCR primer pairs and template standards for TMEM57   OriGene Protein Over-expression Lysate for TMEM57  
     OriGene MassSpec something-or-other for TMEM57   OriGene clones in human, mouse for TMEM57  
     OriGene qSTAR qPCR primer pairs in human, mouse for TMEM57   OriGene Purified Protein for TMEM57  
     OriGene ORF clones in mouse, rat for TMEM57   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for TMEM57   OriGene Custom Protein Services for TMEM57  

     
     
     Block miRNA regulation of human, mouse, rat TMEM57 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing TMEM57
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TMEM57 Predesigned siRNA for gene silencing in human, mouse, rat TMEM57
     QuantiFast Probe-based Assays in human, mouse, rat TMEM57 QuantiTect SYBR Green Assays in human, mouse, rat TMEM57
     PCR Arrays including human, mouse, rat TMEM57 Search Chromatin IP Primers for TMEM57
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMEM57  Search GeneGlobe Interaction Network for TMEM57
     Regulatory tfbs in TMEM57 promoter
     GenScript Custom Purified and Recombinant Proteins Services for TMEM57 GenScript cDNA clones with any tag delivered in your preferred vector for TMEM57
     GenScript Custom Assay Services for TMEM57 GenScript Custom overexpressing Cell Line Services for TMEM57
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for TMEM57 (MACOI)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     TMEM57 antibodies
     TMEM57 lysates
     Antibodies for TMEM57
     See all of Abcam's Antibodies, Kits and Proteins for TMEM57
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for TMEM57
     Antibodies for TMEM57
     ELISAs for TMEM57
     CLIAs for TMEM57



     Browse ESI BIO Cell Lines and PureStem Progenitors for TMEM57
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM57
     Browse SwitchGear 3'UTR luciferase reporter plasmids for TMEM57
     Browse SwitchGear Promoter luciferase reporter plasmids for TMEM57
     ThermoFisher Antibodies for TMEM57
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM57
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TMEM57
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TMEM57
     LSBio Antibodies in human, mouse, rat for TMEM57
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
     Search Addgene for plasmids for TMEM57
      Search eBioscience for proteins for TMEM57
      Search eBioscience for elisas for TMEM57
      eBioscience FlowRNA Probe Sets
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      TMEM57 gene at Home site.
    Version: 3.12.224 13 Oct 2014
    hostname: 356980-web2.xennexinc.com index build: 128 solr: 1.4