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TMEM54 Gene

protein-coding   GIFtS: 46
GCID: GC01M033360

Transmembrane Protein 54

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): antisense

Quality score for the ORGUL clustered with this gene is 3

Aliases
Transmembrane Protein 541 2
Beta-Casein-Like Protein2 3
Protein CAC-12 3
BCLP2 3
CAC12 3
CAC-12

External Ids:    HGNC: 241431   Entrez Gene: 1134522   Ensembl: ENSG000001219007   UniProtKB: Q969K73   
ORGUL members:         

Export aliases for TMEM54 gene to outside databases

Previous GC identifers: GC01M033030 GC01M033133 GC01M031475


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TMEM54 Gene:
TMEM54 (transmembrane protein 54) is a protein-coding gene. Diseases associated with TMEM54 include hard palate cancer, and cervical adenocarcinoma. An important paralog of this gene is KRTCAP3.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000001.11  NT_032977.10  NC_018912.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the TMEM54 gene promoter:
         NF-1   NF-1/L   AP-1   MyoD   CUTL1   PPAR-gamma1   NRF-2   IRF-7A   PPAR-gamma2   RSRFC4   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTMEM54 promoter sequence
   Search Chromatin IP Primers for TMEM54

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TMEM54


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p35-p34   Ensembl cytogenetic band:  1p35.1   HGNC cytogenetic band: 1p35-p34

TMEM54 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMEM54 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M033360:  view genomic region     (about GC identifiers)

Start:
33,360,195 bp from pter      End:
33,367,039 bp from pter
Size:
6,845 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: TMM54_HUMAN, Q969K7 (See protein sequence)
Recommended Name: Transmembrane protein 54  
Size: 222 amino acids; 23772 Da
Sequence caution: Sequence=BAA87335.1; Type=Frameshift; Positions=106, 165, 168, 222;
Secondary accessions: Q6UV18 Q8IVD0 Q9UM12
Alternative splicing: 3 isoforms:  Q969K7-1   Q969K7-2   Q969K7-3   

Explore the universe of human proteins at neXtProt for TMEM54: NX_Q969K7

Explore proteomics data for TMEM54 at MOPED


See TMEM54 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_277039.1  
ENSEMBL proteins: 
 ENSP00000362562   ENSP00000328630  

TMEM54 Human Recombinant Protein Products:

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OriGene Protein Over-expression Lysate for TMEM54
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Novus Biologicals TMEM54 Protein
Novus Biologicals TMEM54 Lysate
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Browse Sino Biological Cell Lysates
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Cloud-Clone Corp. Proteins for TMEM54

TMEM54 Antibody Products:

Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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OriGene Custom Antibody Services for TMEM54
Novus Biologicals TMEM54 Antibody
Search for Antibodies for TMEM54 at Abcam
Cloud-Clone Corp. Antibodies for TMEM54
Search ThermoFisher Antibodies for TMEM54
Search LSBio for Antibodies for TMEM54

TMEM54 Assay Products:

Browse Kits and Assays available from EMD Millipore
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Browse R&D Systems for biochemical assays
GenScript Custom Assay Services for TMEM54
Browse Enzo Life Sciences for kits & assays
Cloud-Clone Corp. ELISAs for TMEM54
Cloud-Clone Corp. CLIAs for TMEM54


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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1 InterPro protein domain:
 IPR020977 Beta-casein-like

Graphical View of Domain Structure for InterPro Entry Q969K7

ProtoNet protein and cluster: Q969K7

UniProtKB/Swiss-Prot: TMM54_HUMAN, Q969K7
Similarity: Belongs to the TMEM54 family


TMEM54 for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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     Gene Ontology (GO): 1 molecular function term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0003674molecular_function ND--
     
TMEM54 for ontologies           About GeneDecksing


Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TMEM54
   inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TMEM54

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TMEM54
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TMEM54

miRNA
Products:
    
miRTarBase miRNAs that target TMEM54:
hsa-mir-124-3p (MIRT022477)

Block miRNA regulation of human, mouse, rat TMEM54 using miScript Target Protectors
7 qRT-PCR Assays for microRNAs that regulate TMEM54:
hsa-miR-142-5p hsa-miR-152 hsa-miR-148b hsa-miR-2116 hsa-miR-26b* hsa-miR-4276 hsa-miR-148a
SwitchGear 3'UTR luciferase reporter plasmidTMEM54 3' UTR sequence
Inhib. RNA
Products:
    
OriGene RNAi products in human, mouse, rat for TMEM54
Predesigned siRNA for gene silencing in human, mouse, rat TMEM54

Gene Editing
Products:
DNA2.0 Custom Protein Engineering Service for TMEM54

Clone
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OriGene clones in human, mouse for TMEM54 (see all 7)
OriGene ORF clones in mouse, rat for TMEM54
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: TMEM54 (NM_033504)
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM54
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM54

Cell Line
Products:
     
GenScript Custom overexpressing Cell Line Services for TMEM54
Browse ESI BIO Cell Lines and PureStem Progenitors for TMEM54 
In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM54


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
TMM54_HUMAN, Q969K7: Membrane; Multi-pass membrane protein (Potential)
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
plasma membrane3

Gene Ontology (GO): 2 cellular component terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005575cellular_component ND--
GO:0016021integral component of membrane IEA--

TMEM54 for ontologies           About GeneDecksing


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TMEM54
Interactions:

    Search GeneGlobe Interaction Network for TMEM54

STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

3 Interacting proteins for TMEM54 (Q969K72 ENSP000003625624) via UniProtKB, MINT, STRING, and/or I2D
InteractantInteraction Details
GeneCardExternal ID(s)
PEX19ENSP000003570514STRING: ENSP00000357051
RBBP8ENSP000003230504STRING: ENSP00000323050
--P310162MINT-8105545
About this table

Gene Ontology (GO): 1 biological process term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0008150biological_process ND--

TMEM54 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for TMEM54 (TMM54)



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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REFSEQ mRNAs for TMEM54 gene: 
NM_033504.2  

Unigene Cluster for TMEM54:

Transmembrane protein 54
Hs.534521  [show with all ESTs]
Unigene Representative Sequence: BC020497
6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000482771 ENST00000373463(uc001bwi.1 uc001bwk.1) ENST00000329151(uc001bwj.1)
ENST00000474144 ENST00000475208 ENST00000463914
miRNA
Products:
     
Block miRNA regulation of human, mouse, rat TMEM54 using miScript Target Protectors
7 qRT-PCR Assays for microRNAs that regulate TMEM54:
hsa-miR-142-5p hsa-miR-152 hsa-miR-148b hsa-miR-2116 hsa-miR-26b* hsa-miR-4276 hsa-miR-148a
SwitchGear 3'UTR luciferase reporter plasmidTMEM54 3' UTR sequence
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for TMEM54
Predesigned siRNA for gene silencing in human, mouse, rat TMEM54
Clone
Products:
     
OriGene clones in human, mouse for TMEM54 (see all 7)
OriGene ORF clones in mouse, rat for TMEM54
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: TMEM54 (NM_033504)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM54
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM54
Primer
Products:
    
OriGene qPCR primer pairs and template standards for TMEM54
OriGene qSTAR qPCR primer pairs in human, mouse for TMEM54
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMEM54
  QuantiTect SYBR Green Assays in human, mouse, rat TMEM54
  QuantiFast Probe-based Assays in human, mouse, rat TMEM54

Additional mRNA sequence: 

AB012692.1 AY027543.1 AY359883.1 BC001418.3 BC013953.2 BC020497.1 BC023260.1 BC127891.1 

7 DOTS entries:

DT.211888  DT.101983492  DT.97818557  DT.95267195  DT.95267191  DT.92057871  DT.102827261 

Selected AceView cDNA sequences (see all 133):

BG422949 BE907056 BU627966 BU506916 BM976334 BG823019 AI623229 AI347181 
BM126893 CA489748 NM_033504 AI277081 BF812889 BC001418 BG824476 CA435403 
BU944769 BM759137 BC023260 BU630426 BI093522 CR596164 CA312902 BC013953 

GeneLoc Exon Structure

Selected Alternative Splicing Database (ASD) splice patterns (SP) for TMEM54 (see all 7)    About this scheme

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8
SP1:                                -     -                                       
SP2:                                                                              
SP3:                                -     -     -                                 
SP4:                                -     -     -     -                           
SP5:                                -     -           -                           


ECgene alternative splicing isoforms for TMEM54

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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TMEM54 expression in normal human tissues (normalized intensities)      TMEM54 embryonic expression: see
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: ATGCGGGAGA
TMEM54 Expression
About this image


TMEM54 expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database
 selected tissues (see all 4) fully expand
 
 Epithelial Cells
         Podocytes Podocyte Layer
 
 Hair (Integumentary System)
         Bulge Stem Cells Bulge
 
 Kidney (Urinary System)
         Podocytes Podocyte Layer
 
 Colon (Gastrointestinal Tract)
TMEM54 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

TMEM54 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.534521

UniProtKB/Swiss-Prot: TMM54_HUMAN, Q969K7
Tissue specificity: Ubiquitously expressed in cancer cell lines

    Custom PCR Arrays for TMEM54
Primer
Products:
OriGene qPCR primer pairs and template standards for TMEM54
OriGene qSTAR qPCR primer pairs in human, mouse for TMEM54
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMEM54
QuantiTect SYBR Green Assays in human, mouse, rat TMEM54
QuantiFast Probe-based Assays in human, mouse, rat TMEM54
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM54

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of chordates.

Orthologs for TMEM54 gene from Selected species (see all 10)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Tmem541 , 5 transmembrane protein 541, 5 79.42(n)1
76.5(a)1
  4 (62.86 cM)5
662601  NM_025452.41  NP_079728.21 
 1291055485 
lizard
(Anolis carolinensis)
Reptilia TMEM546
transmembrane protein 54
47(a)
1 ↔ 1
GL343711.1(38398-57291)
tropical clawed frog
(Xenopus tropicalis)
Amphibia tmem541 transmembrane protein 54 52.24(n)
45.77(a)
  100485545  XM_002940024.2  XP_002940070.2 
zebrafish
(Danio rerio)
Actinopterygii TMEM54 (2 of 2)6
tmem546
transmembrane protein 54
26(a)
24(a)
many → 1
many → 1
17(25115972-25132192) ENSDARG00000059247
19(33979091-33994721) ENSDARG00000035875


ENSEMBL Gene Tree for TMEM54 (if available)
TreeFam Gene Tree for TMEM54 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for TMEM54 gene
KRTCAP32  
1 SIMAP similar gene for TMEM54 using alignment to 1 protein entry:     TMM54_HUMAN:
KRTCAP3

TMEM54 for paralogs           About GeneDecksing



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for TMEM54 (see all 182)    About this table    
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 1 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1902048161,2
--33360824(+) ATACAC/TAGGGG 1 -- int10--------
rs1449831761,2
C--33360863(+) AGGGGA/CTCCCA 1 -- int10--------
rs756110371,2
C--33360876(+) AAATTC/TGGGGA 1 -- int11Minor allele frequency- T:0.01WA 118
rs1491677131,2
C--33360887(+) GTCAGC/GGCTGT 1 -- int10--------
rs2017829441,2
--33360977(+) GCGTAC/TAGCAA 2 I V mis10--------
rs2007810611,2
C--33360993(+) TTCTCC/TGCCAC 2 A syn10--------
rs2001428581,2
C--33360998(+) CGCCAA/C/TGCAGA 3 M V L mis10--------
rs1436771321,2
C,F--33360999(+) GCCACG/ACAGAG 2 /C syn12Minor allele frequency- A:0.00NA EU 5037
rs2011822931,2
--33361005(+) CAGAGC/TACTAG 2 V syn10--------
rs1467345081,2
C--33361013(+) TAGGGC/TGATGC 2 T A mis11Minor allele frequency- T:0.00NA 4432

HapMap Linkage Disequilibrium report for TMEM54 (33360195 - 33367039 bp)

Structural Variations
     Database of Genomic Variants (DGV) 2 variations for TMEM54:    About this table    
Variant IDTypeSubtypePubMed ID
dgv212n71CNV Loss21882294
nsv516302CNV Loss19592680

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing TMEM54
DNA2.0 Custom Variant and Variant Library Synthesis for TMEM54

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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7 diseases for TMEM54:    About MalaCards
hard palate cancer    cervical adenocarcinoma    cleft palate    cleft lip
cervicitis    adenocarcinoma    hiv-1

3 diseases from the University of Copenhagen DISEASES database for TMEM54:
Cleft lip     Cleft palate     Hard palate cancer

TMEM54 for disorders           About GeneDecksing


Export disorders for TMEM54 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for TMEM54 gene, integrated from 10 sources (see all 13):
(articles sorted by number of sources associating them with TMEM54)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Cloning and characterization of a cDNA fragment coding beta-casein- like protein preferentially expressed in cervical adenocarcinoma cell line CAC-1. (PubMed id 9500206)1, 2, 3, 9 Suzuki T.... Kudo R. (Cancer Lett. 1998)
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  3. Cloning and characterization of a tumor-associated antigen, beta- casein-like protein. (PubMed id 11394883)1, 2 Baba T.... Kudo R. (Biochem. Biophys. Res. Commun. 2001)
  4. Identification and characterization of CAC1 as a novel CDK2- associated cullin. (PubMed id 19829063)1, 9 Kong Y.... Yin Y. (Cell Cycle 2009)
  5. CAC1 negatively regulates RARI+ activity through cooperation with HDAC. (PubMed id 22982681)1 Moon M....Kim E.J. (Biochem. Biophys. Res. Commun. 2012)
  6. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)
  7. The SH3 domain of postsynaptic density 95 mediates inflammatory pain through phosphatidylinositol-3-kinase recruitment. (PubMed id 20467438)1 Arbuckle M.I....Grant S.G. (EMBO Rep. 2010)
  8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
  9. Specific detection of circulating tumor cells by reverse transcriptase-polymerase chain reaction of a beta-casein-like protein, preferentially expressed in malignant neoplasms. (PubMed id 11724320)9 Baba T....Kudo R. (Anticancer Res. 2001)
  10. The dimerization domain of the HIV-1 capsid protein binds a capsid protein-derived peptide: a biophysical characterization. (PubMed id 15152086)9 GarzA^n M.T....Neira J.L. (Protein Sci. 2004)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 113452 HGNC: 24143 AceView: BCLP Ensembl:ENSG00000121900 euGenes: HUgn113452
ECgene: TMEM54 H-InvDB: TMEM54

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for TMEM54 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for TMEM54 gene:
Search GeneIP for patents involving TMEM54

GeneCards and IP:
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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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 Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for TMEM54  
 OriGene qPCR primer pairs and template standards for TMEM54   OriGene Protein Over-expression Lysate for TMEM54  
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 Block miRNA regulation of human, mouse, rat TMEM54 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing TMEM54
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 Search Tocris compounds for TMEM54 (TMM54)
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 Novus Tissue Slides
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 Search for Antibodies for TMEM54 at Abcam
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 Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM54
 inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TMEM54
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GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

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