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Aliases for TMEM51 Gene

Aliases for TMEM51 Gene

  • Transmembrane Protein 51 2 3
  • C1orf72 3 4
  • Chromosome 1 Open Reading Frame 72 2

External Ids for TMEM51 Gene

Previous Symbols for TMEM51 Gene

  • C1orf72

Summaries for TMEM51 Gene

GeneCards Summary for TMEM51 Gene

TMEM51 is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM51 Gene

Genomics for TMEM51 Gene

Genomic Location for TMEM51 Gene

Start:
15,152,532 bp from pter
End:
15,220,480 bp from pter
Size:
67,949 bases
Orientation:
Plus strand

Genomic View for TMEM51 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMEM51 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM51 Gene

Regulatory Elements for TMEM51 Gene

Proteins for TMEM51 Gene

  • Protein details for TMEM51 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NW97-TMM51_HUMAN
    Recommended name:
    Transmembrane protein 51
    Protein Accession:
    Q9NW97
    Secondary Accessions:
    • A8K819

    Protein attributes for TMEM51 Gene

    Size:
    253 amino acids
    Molecular mass:
    27759 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMEM51 Gene

Proteomics data for TMEM51 Gene at MOPED

Post-translational modifications for TMEM51 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for TMEM51 Gene

Domains for TMEM51 Gene

Protein Domains for TMEM51 Gene

InterPro:
ProtoNet:
genes like me logo Genes that share domains with TMEM51: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TMEM51 Gene

Function for TMEM51 Gene

Gene Ontology (GO) - Molecular Function for TMEM51 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with TMEM51: view

Phenotypes for TMEM51 Gene

GenomeRNAi human phenotypes for TMEM51:
genes like me logo Genes that share phenotypes with TMEM51: view

miRNA for TMEM51 Gene

miRTarBase miRNAs that target TMEM51

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for TMEM51 Gene

Localization for TMEM51 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM51 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TMEM51 Gene COMPARTMENTS Subcellular localization image for TMEM51 gene
Compartment Confidence
extracellular 2
cytosol 1
endoplasmic reticulum 1
golgi apparatus 1
mitochondrion 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for TMEM51 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM51: view

Pathways for TMEM51 Gene

SuperPathways for TMEM51 Gene

No Data Available

Interacting Proteins for TMEM51 Gene

Gene Ontology (GO) - Biological Process for TMEM51 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with TMEM51: view

No data available for Pathways by source for TMEM51 Gene

Transcripts for TMEM51 Gene

Unigene Clusters for TMEM51 Gene

Transmembrane protein 51:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM51 Gene

ExUns: 1a · 1b ^ 2a · 2b · 2c · 2d ^ 3 ^ 4a · 4b ^ 5a · 5b · 5c · 5d ^ 6
SP1: - - - -
SP2:
SP3:
SP4: - - - - -
SP5: -
SP6: - -
SP7: - -

Relevant External Links for TMEM51 Gene

GeneLoc Exon Structure for
TMEM51
ECgene alternative splicing isoforms for
TMEM51

Expression for TMEM51 Gene

mRNA expression in normal human tissues for TMEM51 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for TMEM51 Gene

This gene is overexpressed in Pancreas (4.2).

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for TMEM51 Gene

SOURCE GeneReport for Unigene cluster for TMEM51 Gene Hs.465305

genes like me logo Genes that share expressions with TMEM51: view

Orthologs for TMEM51 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TMEM51 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TMEM51 36
  • 98.81 (n)
  • 100 (a)
TMEM51 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia TMEM51 36
  • 86.83 (n)
  • 91.53 (a)
TMEM51 37
  • 91 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TMEM51 36
  • 86.13 (n)
  • 90 (a)
TMEM51 37
  • 90 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tmem51 36
  • 82.2 (n)
  • 85.54 (a)
Tmem51 16
Tmem51 37
  • 86 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia TMEM51 37
  • 79 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia TMEM51 37
  • 78 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Tmem51 36
  • 83.94 (n)
  • 87.15 (a)
chicken
(Gallus gallus)
Aves TMEM51 36
  • 67.9 (n)
  • 64.75 (a)
TMEM51 37
  • 65 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia TMEM51 37
  • 56 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia tmem51 36
  • 59.58 (n)
  • 57.92 (a)
zebrafish
(Danio rerio)
Actinopterygii tmem51a 36
  • 51.43 (n)
  • 42.38 (a)
tmem51a 37
  • 33 (a)
OneToMany
tmem51b 37
  • 34 (a)
OneToMany
Species with no ortholog for TMEM51:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TMEM51 Gene

ENSEMBL:
Gene Tree for TMEM51 (if available)
TreeFam:
Gene Tree for TMEM51 (if available)

Paralogs for TMEM51 Gene

No data available for Paralogs for TMEM51 Gene

Variants for TMEM51 Gene

Sequence variations from dbSNP and Humsavar for TMEM51 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs549 -- 15,220,329(+) GATGC(A/G)TAATA utr-variant-3-prime
rs4059 -- 15,220,213(-) GTGTC(C/T)TTTCT utr-variant-3-prime
rs7681 -- 15,220,265(+) CTCTC(A/G)CAGAG utr-variant-3-prime
rs10130 -- 15,220,067(+) GAAAG(A/G)GTTCC utr-variant-3-prime
rs742668 -- 15,193,186(-) TAATT(C/T)AGAAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TMEM51 Gene

Variant ID Type Subtype PubMed ID
nsv833425 CNV Gain 17160897
nsv508913 CNV Insertion 20534489
esv2664046 CNV Deletion 23128226
nsv437203 CNV Loss 16327808
nsv441682 CNV CNV 18776908
nsv519926 CNV Loss 19592680
esv271128 CNV Insertion 20981092
esv273758 CNV Insertion 20981092
nsv159446 CNV Loss 16902084
nsv460550 CNV Gain 19166990
esv2750811 CNV Gain 17911159
nsv871101 CNV Loss 21882294

Relevant External Links for TMEM51 Gene

HapMap Linkage Disequilibrium report
TMEM51

Disorders for TMEM51 Gene

Relevant External Links for TMEM51

Genetic Association Database (GAD)
TMEM51
Human Genome Epidemiology (HuGE) Navigator
TMEM51
genes like me logo Genes that share disorders with TMEM51: view

No data available for UniProtKB/Swiss-Prot for TMEM51 Gene

Publications for TMEM51 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4
  5. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 49

Products for TMEM51 Gene

Sources for TMEM51 Gene

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