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Aliases for TMEM47 Gene

Aliases for TMEM47 Gene

  • Transmembrane 4 Superfamily Member 10 2 3 4
  • BCMP1 3 4 6
  • Brain Cell Membrane Protein 1 3 4
  • Transmembrane Protein 47 2 3
  • TM4SF10 3 4

External Ids for TMEM47 Gene

Previous Symbols for TMEM47 Gene

  • TM4SF10

Summaries for TMEM47 Gene

Entrez Gene Summary for TMEM47 Gene

  • This gene encodes a member of the PMP22/EMP/claudin protein family. The encoded protein is localized to the ER and the plasma membrane. In dogs, transcripts of this gene exist at high levels in the brain. [provided by RefSeq, Jul 2008]

GeneCards Summary for TMEM47 Gene

TMEM47 is a Protein Coding gene. An important paralog of this gene is PERP.

Gene Wiki entry for TMEM47 Gene

No data available for UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM47 Gene

Genomics for TMEM47 Gene

Genomic Location for TMEM47 Gene

Start:
34,627,064 bp from pter
End:
34,657,288 bp from pter
Size:
30,225 bases
Orientation:
Minus strand

Genomic View for TMEM47 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMEM47 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM47 Gene

Regulatory Elements for TMEM47 Gene

Proteins for TMEM47 Gene

  • Protein details for TMEM47 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9BQJ4-TMM47_HUMAN
    Recommended name:
    Transmembrane protein 47
    Protein Accession:
    Q9BQJ4
    Secondary Accessions:
    • Q5JR44

    Protein attributes for TMEM47 Gene

    Size:
    181 amino acids
    Molecular mass:
    19998 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMEM47 Gene

Proteomics data for TMEM47 Gene at MOPED

Post-translational modifications for TMEM47 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TMEM47 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TMEM47 Gene

Domains for TMEM47 Gene

Protein Domains for TMEM47 Gene

UniProtKB/Swiss-Prot:

TMM47_HUMAN
Family:
  • Belongs to the TMEM47 family.:
    • Q9BQJ4
genes like me logo Genes that share domains with TMEM47: view

No data available for Gene Families for TMEM47 Gene

Function for TMEM47 Gene

Gene Ontology (GO) - Molecular Function for TMEM47 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
genes like me logo Genes that share ontologies with TMEM47: view

miRNA for TMEM47 Gene

miRTarBase miRNAs that target TMEM47

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for TMEM47 Gene

Localization for TMEM47 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM47 Gene

Membrane; Multi-pass membrane protein. Cell junction.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TMEM47 Gene COMPARTMENTS Subcellular localization image for TMEM47 gene
Compartment Confidence
plasma membrane 4

Gene Ontology (GO) - Cellular Components for TMEM47 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IDA --
GO:0005911 cell-cell junction IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM47: view

Pathways for TMEM47 Gene

SuperPathways for TMEM47 Gene

No Data Available

Interacting Proteins for TMEM47 Gene

Gene Ontology (GO) - Biological Process for TMEM47 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with TMEM47: view

No data available for Pathways by source for TMEM47 Gene

Transcripts for TMEM47 Gene

mRNA/cDNA for TMEM47 Gene

(1) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(138) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TMEM47 Gene

Transmembrane protein 47:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM47 Gene

No ASD Table

Relevant External Links for TMEM47 Gene

GeneLoc Exon Structure for
TMEM47
ECgene alternative splicing isoforms for
TMEM47

Expression for TMEM47 Gene

mRNA expression in normal human tissues for TMEM47 Gene

mRNA differential expression in normal tissues according to GTEx for TMEM47 Gene

This gene is overexpressed in Artery - Tibial (4.5) and Artery - Aorta (4.5).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for TMEM47 Gene

SOURCE GeneReport for Unigene cluster for TMEM47 Gene Hs.8769

genes like me logo Genes that share expressions with TMEM47: view

Orthologs for TMEM47 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TMEM47 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TMEM47 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia TMEM47 36
  • 96.13 (n)
  • 100 (a)
TMEM47 37
  • 100 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TMEM47 36
  • 96.87 (n)
  • 100 (a)
TMEM47 37
  • 100 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tmem47 36
  • 93.19 (n)
  • 98.9 (a)
Tmem47 16
Tmem47 37
  • 99 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia TMEM47 37
  • 98 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia TMEM47 37
  • 60 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Tmem47 36
  • 92.63 (n)
  • 98.34 (a)
chicken
(Gallus gallus)
Aves TMEM47 36
  • 86.92 (n)
  • 96.13 (a)
TMEM47 37
  • 96 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia TMEM47 37
  • 91 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.10079 36
tropical clawed frog
(Silurana tropicalis)
Amphibia MGC75754 36
tmem47 36
  • 79.33 (n)
  • 92.18 (a)
zebrafish
(Danio rerio)
Actinopterygii tmem47 36
  • 72.93 (n)
  • 82.32 (a)
tmem47 37
  • 82 (a)
OneToOne
wufb99e01 36
Species with no ortholog for TMEM47:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TMEM47 Gene

ENSEMBL:
Gene Tree for TMEM47 (if available)
TreeFam:
Gene Tree for TMEM47 (if available)

Paralogs for TMEM47 Gene

Paralogs for TMEM47 Gene

Selected SIMAP similar genes for TMEM47 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for TMEM47 Gene

genes like me logo Genes that share paralogs with TMEM47: view

Variants for TMEM47 Gene

Sequence variations from dbSNP and Humsavar for TMEM47 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs1127632 -- 34,629,258(-) CCTAA(A/G)AATAA utr-variant-3-prime
rs3813160 -- 34,658,935(-) CACCT(A/C)TTAAT upstream-variant-2KB
rs4269688 -- 34,641,739(+) CCAGA(C/T)GAGAA intron-variant
rs4276835 -- 34,642,529(+) TAGCA(C/T)AGGAA intron-variant
rs4320691 -- 34,636,116(+) GTAAT(A/C)TAAAT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TMEM47 Gene

Variant ID Type Subtype PubMed ID
esv2664433 CNV Deletion 23128226
nsv519268 CNV Gain 19592680
nsv6857 CNV Insertion 18451855

Relevant External Links for TMEM47 Gene

HapMap Linkage Disequilibrium report
TMEM47
Human Gene Mutation Database (HGMD)
TMEM47

Disorders for TMEM47 Gene

Relevant External Links for TMEM47

Genetic Association Database (GAD)
TMEM47
genes like me logo Genes that share disorders with TMEM47: view

No data available for UniProtKB/Swiss-Prot for TMEM47 Gene

Publications for TMEM47 Gene

  1. Identification of the gene encoding Brain Cell Membrane Protein 1 (BCMP1), a putative four-transmembrane protein distantly related to the Peripheral Myelin Protein 22 / Epithelial Membrane Proteins and the Claudins. (PMID: 11472633) Christophe-Hobertus C. … Christophe D. (BMC Genomics 2001) 2 3 23
  2. TM4SF10 gene sequencing in XLMR patients identifies common polymorphisms but no disease-associated mutation. (PMID: 15345028) Christophe-Hobertus C. … Christophe D. (BMC Med. Genet. 2004) 3 23
  3. Novel markers of subclinical disease for Ewing family tumors from gene expression profiling. (PMID: 18056173) Cheung I.Y. … Cheung N.K. (Clin. Cancer Res. 2007) 3 23
  4. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S. … Poustka A. (Genome Res. 2001) 3 4
  5. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4

Products for TMEM47 Gene

Sources for TMEM47 Gene

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