Aliases for TMEM47 Gene
External Ids for TMEM47 Gene
Previous HGNC Symbols for TMEM47 Gene
Previous GeneCards Identifiers for TMEM47 Gene
This gene encodes a member of the PMP22/EMP/claudin protein family. The encoded protein is localized to the ER and the plasma membrane. In dogs, transcripts of this gene exist at high levels in the brain. [provided by RefSeq, Jul 2008]
GeneCards Summary for TMEM47 Gene
TMEM47 (Transmembrane Protein 47) is a Protein Coding gene. An important paralog of this gene is PERP.
UniProtKB/Swiss-Prot for TMEM47 Gene
Regulates cell junction organization in epithelial cells. May play a role in the transition from adherens junction to tight junction assembly. May regulate F-actin polymerization required for tight junctional localization dynamics and affect the junctional localization of PARD6B. During podocyte differentiation may negatively regulate activity of FYN and subsequently the abundance of nephrin (By similarity).