Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



TMEM45B Gene

protein-coding   GIFtS: 46
GCID: GC11P129688

Transmembrane Protein 45B

  Try our

disease database 

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Transmembrane Protein 45B1 2

External Ids:    HGNC: 251941   Entrez Gene: 1202242   Ensembl: ENSG000001517157   UniProtKB: Q96B213   

Export aliases for TMEM45B gene to outside databases

Previous GC identifers: GC11P129191 GC11P125638


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for TMEM45B Gene:
TMEM45B (transmembrane protein 45B) is a protein-coding gene. An important paralog of this gene is TMEM45A.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000011.9  NT_033899.9  NC_018922.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the TMEM45B gene promoter:
         C/EBPbeta   HNF-1   HNF-1A   C/EBPalpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTMEM45B promoter sequence
   Search Chromatin IP Primers for TMEM45B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TMEM45B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q24.3   Ensembl cytogenetic band:  11q24.3   HGNC cytogenetic band: 11q24.3

TMEM45B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMEM45B gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P129688:  view genomic region     (about GC identifiers)

Start:
129,685,714 bp from pter      End:
129,729,898 bp from pter
Size:
44,185 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: TM45B_HUMAN, Q96B21 (See protein sequence)
Recommended Name: Transmembrane protein 45B  
Size: 275 amino acids; 31826 Da
Secondary accessions: A8K2L8

Explore the universe of human proteins at neXtProt for TMEM45B: NX_Q96B21

Explore proteomics data for TMEM45B at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See TMEM45B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_620143.1  
    ENSEMBL proteins: 
     ENSP00000281441   ENSP00000436293  

    TMEM45B Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec
    OriGene Custom Protein Services for TMEM45B
    GenScript Custom Purified and Recombinant Proteins Services for TMEM45B
    Novus Biologicals TMEM45B Protein
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TMEM45B

     
    Search eBioscience for Proteins for TMEM45B 

     
    antibodies-online proteins for TMEM45B (2 products) 

     
    antibodies-online peptides for TMEM45B

    TMEM45B Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for TMEM45B
    Novus Biologicals TMEM45B Antibody
    Abcam antibodies for TMEM45B
    Cloud-Clone Corp. Antibodies for TMEM45B
    Search ThermoFisher Antibodies for TMEM45B
    Search antibodies-online for antibodies for TMEM45B 

    TMEM45B Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for TMEM45B
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for TMEM45B
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for TMEM45B
    Cloud-Clone Corp. CLIAs for TMEM45B
    Search eBioscience for ELISAs for TMEM45B 
    antibodies-online kits for TMEM45B (8 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    1 InterPro protein domain:
     IPR006904 DUF716_TMEM45

    Graphical View of Domain Structure for InterPro Entry Q96B21

    ProtoNet protein and cluster: Q96B21

    UniProtKB/Swiss-Prot: TM45B_HUMAN, Q96B21
    Similarity: Belongs to the TMEM45 family


    Find genes that share domains with TMEM45B           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Phenotypes:
         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Tmem45b):
     no phenotypic analysis 

    Find genes that share phenotypes with TMEM45B           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Tmem45btm1.1Hsue for TMEM45B

       genOway: Develop your customized and physiologically relevant rodent model for TMEM45B

    miRNA
    Products:
        
    miRTarBase miRNAs that target TMEM45B:
    hsa-mir-335-5p (MIRT019035)

    Block miRNA regulation of human, mouse, rat TMEM45B using miScript Target Protectors
    4 qRT-PCR Assays for microRNAs that regulate TMEM45B:
    hsa-miR-653 hsa-miR-548k hsa-miR-205* hsa-miR-1252
    SwitchGear 3'UTR luciferase reporter plasmidTMEM45B 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for TMEM45B
    Predesigned siRNA for gene silencing in human, mouse, rat TMEM45B

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for TMEM45B

    Clone
    Products:
         
    OriGene clones in human, mouse for TMEM45B (see all 7)
    OriGene ORF clones in mouse, rat for TMEM45B
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TMEM45B (NM_138788)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM45B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM45B

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for TMEM45B
    Browse ESI BIO Cell Lines and PureStem Progenitors for TMEM45B 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM45B


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    TM45B_HUMAN, Q96B21: Membrane; Multi-pass membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane3
    cytosol1
    endoplasmic reticulum1
    nucleus1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with TMEM45B           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TMEM45B
    Interactions:

        Search GeneGlobe Interaction Network for TMEM45B

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    2 Interacting proteins for TMEM45B (ENSP000002814414) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TINAGENSP000002597824STRING: ENSP00000259782
    UBE2G2ENSP000003383484STRING: ENSP00000338348
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TMEM45B (TM45B)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for TMEM45B gene: 
    NM_138788.3  

    Unigene Cluster for TMEM45B:

    Transmembrane protein 45B
    Hs.504301  [show with all ESTs]
    Unigene Representative Sequence: AK098106
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000281441(uc001qfe.1 uc001qff.1) ENST00000525709 ENST00000527754
    ENST00000529381 ENST00000524567
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat TMEM45B using miScript Target Protectors
    4 qRT-PCR Assays for microRNAs that regulate TMEM45B:
    hsa-miR-653 hsa-miR-548k hsa-miR-205* hsa-miR-1252
    SwitchGear 3'UTR luciferase reporter plasmidTMEM45B 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for TMEM45B
    Predesigned siRNA for gene silencing in human, mouse, rat TMEM45B
    Clone
    Products:
         
    OriGene clones in human, mouse for TMEM45B (see all 7)
    OriGene ORF clones in mouse, rat for TMEM45B
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TMEM45B (NM_138788)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM45B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM45B
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for TMEM45B
    OriGene qSTAR qPCR primer pairs in human, mouse for TMEM45B
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMEM45B
      QuantiTect SYBR Green Assays in human, mouse, rat TMEM45B
      QuantiFast Probe-based Assays in human, mouse, rat TMEM45B

    Additional mRNA sequence: 

    AK098106.1 AK290283.1 AK292058.1 BC016153.1 

    10 DOTS entries:

    DT.438794  DT.100751648  DT.97829262  DT.99929312  DT.120752401  DT.120752363  DT.75187624  DT.92422843 
    DT.209217  DT.91641524 

    Selected AceView cDNA sequences (see all 128):

    BC016153 BU674569 AA627508 BM827924 BX282180 AW662394 BU076544 BQ082344 
    AA470716 AA860541 NM_138788 BF000269 AW295567 CB850847 BU076284 AK098106 
    BM741999 BF001637 BE217952 AW001377 AW445089 AA135001 BM263694 BM740964 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for TMEM45B (see all 6)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b ^ 7a · 7b · 7c ^ 8 ^ 9
    SP1:        -     -     -     -                                                         
    SP2:                    -     -                                                         
    SP3:              -     -     -                                                         
    SP4:        -           -     -                                                         
    SP5:        -           -                                                               


    ECgene alternative splicing isoforms for TMEM45B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    TMEM45B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GATGAATCCG
    TMEM45B Expression
    About this image


    TMEM45B expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Kidney (Urinary System)    fully expand to see all 2 entries
             Renal Collecting Duct System
     
     Colon (Gastrointestinal Tract)
    TMEM45B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TMEM45B Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.504301
        Custom PCR Arrays for TMEM45B
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for TMEM45B
    OriGene qSTAR qPCR primer pairs in human, mouse for TMEM45B
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMEM45B
    QuantiTect SYBR Green Assays in human, mouse, rat TMEM45B
    QuantiFast Probe-based Assays in human, mouse, rat TMEM45B
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM45B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of chordates.

    Orthologs for TMEM45B gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tmem45b1 , 5 transmembrane protein 45b1, 5 81.82(n)1
    80.36(a)1
      9 (16.90 cM)5
    2351351  NM_144936.11  NP_659185.11 
     314261995 
    chicken
    (Gallus gallus)
    Aves TMEM45B1 transmembrane protein 45B 67.4(n)
    59.49(a)
      419725  XM_004947968.1  XP_004948025.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    Uncharacterized protein
    59(a)
    39(a)
    1 ↔ many
    1 ↔ many
    GL343396.1(960391-963872)
    GL343197.1(47798-51495)
    African clawed frog
    (Xenopus laevis)
    Amphibia 480144782   -- 73.62(n)    48014478 
    zebrafish
    (Danio rerio)
    Actinopterygii tmem45b1 transmembrane protein 45B 61.29(n)
    55.68(a)
      402977  NM_205677.1  NP_991240.1 


    ENSEMBL Gene Tree for TMEM45B (if available)
    TreeFam Gene Tree for TMEM45B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for TMEM45B gene
    TMEM45A2  TEDDM12  
    1 SIMAP similar gene for TMEM45B using alignment to 1 protein entry:     TM45B_HUMAN:
    TMEM45A

    Find genes that share paralogs with TMEM45B           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for TMEM45B (see all 1097)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs344541401,2
    C--129573066(+) AAAAA-/AC/CA 
            
    AGAGC
    1 -- int10--------
    rs1397644191,2
    --129683741(+) TGCCAA/GTGCCC 1 -- us2k10--------
    rs1841633481,2
    C--129683758(+) GTGGAA/TTAAGC 1 -- us2k10--------
    rs1452717251,2
    --129683771(+) CCAGGC/GATCTT 1 -- us2k10--------
    rs598397901,2
    C,F--129683804(+) CAACCC/TCCACT 1 -- us2k11Minor allele frequency- T:0.50WA 2
    rs1810837971,2
    --129683882(+) GGGAGC/GCTTAA 1 -- us2k10--------
    rs609725841,2
    C--129683929(+) ACACA-/AC/CA 
            
    GTGCA
    1 -- us2k10--------
    rs1152711211,2
    C,F--129683949(+) GTGCAG/AAACCA 1 -- us2k11Minor allele frequency- A:0.01WA 118
    rs4853411,2
    C,F,A,H--129683971(+) TGTGTG/ATCCGG 1 -- us2k116Minor allele frequency- A:0.04NS EA NA WA CSA 790
    rs1848699071,2
    --129683974(+) GTATCA/CGGAAT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for TMEM45B (129685714 - 129729898 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for TMEM45B:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv39607CNV Loss16902084

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TMEM45B
    DNA2.0 Custom Variant and Variant Library Synthesis for TMEM45B

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus

    Find genes that share disorders with TMEM45B           About GenesLikeMe

    Genetic Association Database (GAD): TMEM45B
    Human Genome Epidemiology (HuGE) Navigator: TMEM45B (2 documents)

    Export disorders for TMEM45B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for TMEM45B gene, integrated from 10 sources (see all 11):
    (articles sorted by number of sources associating them with TMEM45B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    2. Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity. (PubMed id 19773279)1, 4 Hosgood H.D....Lan Q. (Occup Environ Med 2009)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    6. A genome-wide association search for type 2 diabetes genes in African Americans. (PubMed id 22238593)1 Palmer N.D....Sladek R. (PLoS ONE 2012)
    7. Genome-wide association study in east Asians identifies novel susceptibility loci for breast cancer. (PubMed id 22383897)1 Long J....Zheng W. (PLoS Genet. 2012)
    8. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PubMed id 23251661)1 Comuzzie A.G....Butte N.F. (PLoS ONE 2012)
    9. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)
    10. Identification of VKORC1 interaction partners by split-ubiquitin system and coimmunoprecipitation. (PubMed id 21103663)1 Schaafhausen A....MA1ller C.R. (Thromb. Haemost. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 120224 HGNC: 25194 AceView: LOC120224 Ensembl:ENSG00000151715 euGenes: HUgn120224
    ECgene: TMEM45B H-InvDB: TMEM45B

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for TMEM45B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for TMEM45B gene:
    Search GeneIP for patents involving TMEM45B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for TMEM45B  
     OriGene qPCR primer pairs and template standards for TMEM45B   Browse OriGene Protein Over-expression Lysates  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for TMEM45B  
     OriGene qSTAR qPCR primer pairs in human, mouse for TMEM45B   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for TMEM45B   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for TMEM45B   OriGene Custom Protein Services for TMEM45B  

     
     
     Block miRNA regulation of human, mouse, rat TMEM45B using miScript Target Protectors SeqTarget long-range PCR primers for resequencing TMEM45B
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TMEM45B Predesigned siRNA for gene silencing in human, mouse, rat TMEM45B
     QuantiFast Probe-based Assays in human, mouse, rat TMEM45B QuantiTect SYBR Green Assays in human, mouse, rat TMEM45B
     Custom PCR Arrays for TMEM45B Search Chromatin IP Primers for TMEM45B
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMEM45B  Search GeneGlobe Interaction Network for TMEM45B
     Regulatory tfbs in TMEM45B promoter
     GenScript Custom Purified and Recombinant Proteins Services for TMEM45B GenScript cDNA clones with any tag delivered in your preferred vector for TMEM45B
     GenScript Custom Assay Services for TMEM45B GenScript Custom overexpressing Cell Line Services for TMEM45B
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for TMEM45B (TM45B)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     TMEM45B antibodies
     TMEM45B proteins
     Antibodies for TMEM45B
     See all of Abcam's Antibodies, Kits and Proteins for TMEM45B
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for TMEM45B
     Antibodies for TMEM45B
     ELISAs for TMEM45B
     CLIAs for TMEM45B



     Browse ESI BIO Cell Lines and PureStem Progenitors for TMEM45B
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM45B
     SwitchGear 3'UTR luciferase reporter plasmids for TMEM45B
     SwitchGear Promoter luciferase reporter plasmids for TMEM45B
     Search ThermoFisher Antibodies for TMEM45B
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM45B
     Browse compounds at ApexBio
     Search Addgene for plasmids for TMEM45B
      Search eBioscience for proteins for TMEM45B
      Search eBioscience for elisas for TMEM45B
      eBioscience FlowRNA Probe Sets
     genOway: Develop your customized and physiologically relevant rodent model for TMEM45B
      Search antibodies-online for antibodies for TMEM45B
     antibodies-online kits for TMEM45B (8 products)
     antibodies-online peptides for TMEM45B
     antibodies-online proteins for TMEM45B (2 products)
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 7 Oct 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      TMEM45B gene at Home site.
    Version: 3.12.250 16 Nov 2014
    hostname: 356977-web1.xennexinc.com index build: 128 solr: 1.4