Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



TMEM45A Gene

protein-coding   GIFtS: 43
GCID: GC03P100211

Transmembrane Protein 45A

  Try our

disease database 

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Transmembrane Protein 45A1 2
Dermal Papilla-Derived Protein 72 3
DERP72 3
DNA Polymerase-Transactivated Protein 42 3
Dermal Papilla Derived Protein 72
DNAPTP43

External Ids:    HGNC: 254801   Entrez Gene: 550762   Ensembl: ENSG000001814587   UniProtKB: Q9NWC53   

Export aliases for TMEM45A gene to outside databases

Previous GC identifers: GC03P101695 GC03P097579


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for TMEM45A Gene:
TMEM45A (transmembrane protein 45A) is a protein-coding gene. An important paralog of this gene is TEDDM1.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000003.11  NT_005612.17  NC_018914.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the TMEM45A gene promoter:
         NF-YB   CBF-B   CBF-A   NF-YA   NF-YC   CP1C   CP1A   NF-Y   CBF-C   CBF(2)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTMEM45A promoter sequence
   Search Chromatin IP Primers for TMEM45A

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TMEM45A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q12.2   Ensembl cytogenetic band:  3q12.2   HGNC cytogenetic band: 3q12.2

TMEM45A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMEM45A gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P100211:  view genomic region     (about GC identifiers)

Start:
100,211,463 bp from pter      End:
100,296,288 bp from pter
Size:
84,826 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: TM45A_HUMAN, Q9NWC5 (See protein sequence)
Recommended Name: Transmembrane protein 45A  
Size: 275 amino acids; 31680 Da
Secondary accessions: Q53YW5

Explore the universe of human proteins at neXtProt for TMEM45A: NX_Q9NWC5

Explore proteomics data for TMEM45A at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys43, Lys263
  • Modification sites at PhosphoSitePlus

  • See TMEM45A Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_060474.1  
    ENSEMBL proteins: 
     ENSP00000319009   ENSP00000385089   ENSP00000405597  

    TMEM45A Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for TMEM45A
    OriGene Custom MassSpec
    OriGene Custom Protein Services for TMEM45A
    GenScript Custom Purified and Recombinant Proteins Services for TMEM45A
    Novus Biologicals TMEM45A Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TMEM45A

     
    Search eBioscience for Proteins for TMEM45A 

    TMEM45A Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for TMEM45A
    Novus Biologicals TMEM45A Antibody
    Abcam antibodies for TMEM45A
    Cloud-Clone Corp. Antibodies for TMEM45A
    Search ThermoFisher Antibodies for TMEM45A
    Search LSBio for Antibodies for TMEM45A

    TMEM45A Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for TMEM45A
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for TMEM45A
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for TMEM45A
    Cloud-Clone Corp. CLIAs for TMEM45A
    Search eBioscience for ELISAs for TMEM45A 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    1 InterPro protein domain:
     IPR006904 DUF716_TMEM45

    Graphical View of Domain Structure for InterPro Entry Q9NWC5

    ProtoNet protein and cluster: Q9NWC5

    UniProtKB/Swiss-Prot: TM45A_HUMAN, Q9NWC5
    Similarity: Belongs to the TMEM45 family


    Find genes that share domains with TMEM45A           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TMEM45A
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TMEM45A

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TMEM45A
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TMEM45A

    miRNA
    Products:
        
    miRTarBase miRNAs that target TMEM45A:
    hsa-mir-98-5p (MIRT027434), hsa-mir-124-3p (MIRT022364), hsa-mir-181a-5p (MIRT025064), hsa-mir-19b-3p (MIRT031196)

    Block miRNA regulation of human, mouse, rat TMEM45A using miScript Target Protectors
    4 qRT-PCR Assays for microRNAs that regulate TMEM45A:
    hsa-miR-3671 hsa-miR-19b hsa-miR-19a hsa-miR-548aa
    SwitchGear 3'UTR luciferase reporter plasmidTMEM45A 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for TMEM45A
    Predesigned siRNA for gene silencing in human, mouse, rat TMEM45A

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for TMEM45A

    Clone
    Products:
         
    OriGene clones in human, mouse for TMEM45A (see all 6)
    OriGene ORF clones in mouse, rat for TMEM45A
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TMEM45A (NM_018004)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM45A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM45A

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for TMEM45A
    Browse ESI BIO Cell Lines and PureStem Progenitors for TMEM45A 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM45A

    Flow Cytometry
    Products:
       

     
    eBioscience FlowRNA Probe Sets ( VA1-13881) for TMEM45A 


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    TM45A_HUMAN, Q9NWC5: Membrane; Multi-pass membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane3
    cytoskeleton1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with TMEM45A           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TMEM45A
    Interactions:

        Search GeneGlobe Interaction Network for TMEM45A

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for TMEM45A (ENSP000003190094) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TMEM45A (TM45A)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for TMEM45A gene: 
    NM_018004.1  

    Unigene Cluster for TMEM45A:

    Transmembrane protein 45A
    Hs.658956  [show with all ESTs]
    Unigene Representative Sequence: BX648832
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000323523(uc003dtz.1) ENST00000403410(uc003dua.1) ENST00000449609
    ENST00000462884 ENST00000485260 ENST00000489060(uc003dub.1) ENST00000488904

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat TMEM45A using miScript Target Protectors
    4 qRT-PCR Assays for microRNAs that regulate TMEM45A:
    hsa-miR-3671 hsa-miR-19b hsa-miR-19a hsa-miR-548aa
    SwitchGear 3'UTR luciferase reporter plasmidTMEM45A 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for TMEM45A
    Predesigned siRNA for gene silencing in human, mouse, rat TMEM45A
    Clone
    Products:
         
    OriGene clones in human, mouse for TMEM45A (see all 6)
    OriGene ORF clones in mouse, rat for TMEM45A
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TMEM45A (NM_018004)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM45A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM45A
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for TMEM45A
    OriGene qSTAR qPCR primer pairs in human, mouse for TMEM45A
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMEM45A
      QuantiTect SYBR Green Assays in human, mouse, rat TMEM45A
      QuantiFast Probe-based Assays in human, mouse, rat TMEM45A
    Flow Cytometry
    Products:
       

     
    eBioscience FlowRNA Probe Sets ( VA1-13881) for TMEM45A 

    Additional mRNA sequence: 

    AB013911.1 AK000996.1 AK129789.1 AY450392.1 BC040355.1 BX648832.1 

    15 DOTS entries:

    DT.85102274  DT.91766870  DT.100789006  DT.99971783  DT.100685375  DT.100717620  DT.100789007  DT.120866828 
    DT.91766872  DT.95171572  DT.100025371  DT.100789010  DT.120866860  DT.91766878  DT.100641952 

    Selected AceView cDNA sequences (see all 204):

    BG740917 AK129789 AA243811 BG741352 CA390584 BX091604 AW316693 BG695847 
    BG676589 BG697945 BG698931 BU688203 BG674271 AI474277 BM921741 AB013911 
    T25086 BC040355 BG184756 BG697798 BU674675 BM955726 AI333933 BX464856 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    TMEM45A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    TMEM45A Expression
    About this image


    TMEM45A expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 8) fully expand
     
     Kidney (Urinary System)    fully expand to see all 2 entries
             Metanephric Mesenchyme Cells Metanephric Mesenchyme
             Metanephros
     
     Neural Crest (Gastrulation Derivatives)
             PureStem SK11, NCr-fac & Meso-prx Progenitor
     
     Peripheral Nervous System (Nervous System)
             Immature Schwann Cells Peripheral Nerve Domain
     
     Gonad (Reproductive System)
             Primordial Germ Cells Primitive Gonad
     
     Paraxial Mesoderm (Gastrulation Derivatives)
             PureStem SK11, NCr-fac & Meso-prx Progenitor
    TMEM45A Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TMEM45A Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.658956
        Custom PCR Arrays for TMEM45A
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for TMEM45A
    OriGene qSTAR qPCR primer pairs in human, mouse for TMEM45A
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMEM45A
    QuantiTect SYBR Green Assays in human, mouse, rat TMEM45A
    QuantiFast Probe-based Assays in human, mouse, rat TMEM45A
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM45A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of chordates.

    Orthologs for TMEM45A gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tmem45a1 , 5 transmembrane protein 45a1, 5 73.51(n)1
    64.64(a)1
      16 (34.22 cM)5
    562771  NM_019631.31  NP_062605.21 
     568051615 
    chicken
    (Gallus gallus)
    Aves TMEM45A6
    Gallus gallus transmembrane protein 45A (TMEM45A),...
    54(a)
    1 ↔ 1
    1(84325490-84334210)
    lizard
    (Anolis carolinensis)
    Reptilia TMEM45A6
    transmembrane protein 45A
    53(a)
    1 ↔ 1
    3(174111556-174130001)
    zebrafish
    (Danio rerio)
    Actinopterygii TMEM45A6
    transmembrane protein 45A
    46(a)
    1 ↔ 1
    6(36770133-36786048) ENSDARG00000070743


    ENSEMBL Gene Tree for TMEM45A (if available)
    TreeFam Gene Tree for TMEM45A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for TMEM45A gene
    TEDDM12  TMEM45B2  
    1 SIMAP similar gene for TMEM45A using alignment to 3 protein entries:     TM45A_HUMAN (see all proteins):
    TMEM45B

    Find genes that share paralogs with TMEM45A           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for TMEM45A (see all 1672)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs130954221,2
    C,H--100209517(+) TTTAGT/GGATTT 1 -- us2k15Minor allele frequency- G:0.00NS EA NA 388
    rs284169931,2
    C,F--100209543(+) TGCCTG/TTTGAT 1 -- us2k12Minor allele frequency- T:0.08WA 120
    rs1473620111,2
    --100209544(+) GCCTGC/TTGATG 1 -- us2k10--------
    rs117075811,2
    C,F,A,H--100209602(+) ttgagC/Tggctt 1 -- us2k122Minor allele frequency- T:0.12NS EA NA WA 2642
    rs754240831,2
    C,F--100209799(+) TGTGGG/TGGTCT 1 -- us2k13Minor allele frequency- T:0.36CSA WA 122
    rs738606691,2
    C,F--100209808(+) CTTACG/AGAGTT 1 -- us2k12Minor allele frequency- A:0.50WA CSA 4
    rs76187911,2
    C,F,A,H--100210150(+) aggatC/Ttagtt 1 -- us2k120Minor allele frequency- T:0.29NS EA NA WA CSA 1212
    rs748694711,2
    C--100210242(+) TGTTGC/GGCAGC 1 -- us2k10--------
    rs781913321,2
    C--100210243(+) GTTGCA/GCAGCA 1 -- us2k10--------
    rs1868696411,2
    --100210324(+) TCTGAA/CCCCTG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for TMEM45A (100211463 - 100296288 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for TMEM45A:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv877218CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TMEM45A
    DNA2.0 Custom Variant and Variant Library Synthesis for TMEM45A

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for TMEM45A gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with TMEM45A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    4. TMEM45A is essential for hypoxia-induced chemoresistance in breast and liver cancer cells. (PubMed id 22954140)1 Flamant L....Michiels C. (BMC Cancer 2012)
    5. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    6. Ubiquitin ligase substrate identification through quantitative proteomics at both the protein and peptide levels. (PubMed id 21987572)1 Lee K.A....Doedens J.R. (J. Biol. Chem. 2011)
    7. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    8. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    9. Global identification of modular cullin-RING ligase substrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (Cell 2011)
    10. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (Genomics 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 55076 HGNC: 25480 AceView: FLJ10134 Ensembl:ENSG00000181458 euGenes: HUgn55076
    ECgene: TMEM45A H-InvDB: TMEM45A

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for TMEM45A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for TMEM45A gene:
    Search GeneIP for patents involving TMEM45A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for TMEM45A  
     OriGene qPCR primer pairs and template standards for TMEM45A   OriGene Protein Over-expression Lysate for TMEM45A  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for TMEM45A  
     OriGene qSTAR qPCR primer pairs in human, mouse for TMEM45A   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for TMEM45A   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for TMEM45A   OriGene Custom Protein Services for TMEM45A  

     
     
     Block miRNA regulation of human, mouse, rat TMEM45A using miScript Target Protectors SeqTarget long-range PCR primers for resequencing TMEM45A
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TMEM45A Predesigned siRNA for gene silencing in human, mouse, rat TMEM45A
     QuantiFast Probe-based Assays in human, mouse, rat TMEM45A QuantiTect SYBR Green Assays in human, mouse, rat TMEM45A
     Custom PCR Arrays for TMEM45A Search Chromatin IP Primers for TMEM45A
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMEM45A  Search GeneGlobe Interaction Network for TMEM45A
     Regulatory tfbs in TMEM45A promoter
     GenScript Custom Purified and Recombinant Proteins Services for TMEM45A GenScript cDNA clones with any tag delivered in your preferred vector for TMEM45A
     GenScript Custom Assay Services for TMEM45A GenScript Custom overexpressing Cell Line Services for TMEM45A
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for TMEM45A (TM45A)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     TMEM45A antibodies
     TMEM45A lysates
     Antibodies for TMEM45A
     See all of Abcam's Antibodies, Kits and Proteins for TMEM45A
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for TMEM45A
     Antibodies for TMEM45A
     ELISAs for TMEM45A
     CLIAs for TMEM45A



     Browse ESI BIO Cell Lines and PureStem Progenitors for TMEM45A
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM45A
     SwitchGear 3'UTR luciferase reporter plasmids for TMEM45A
     SwitchGear Promoter luciferase reporter plasmids for TMEM45A
     Search ThermoFisher Antibodies for TMEM45A
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM45A
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TMEM45A
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TMEM45A
     Search LSBio for Antibodies for TMEM45A
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
     Search Addgene for plasmids for TMEM45A
      Search eBioscience for proteins for TMEM45A
      Search eBioscience for elisas for TMEM45A
      eBioscience FlowRNA Probe Sets
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      TMEM45A gene at Home site.
    Version: 3.12.224 13 Oct 2014
    hostname: 356977-web1.xennexinc.com index build: 128 solr: 1.4