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Aliases for TMEM42 Gene

Aliases for TMEM42 Gene

  • Transmembrane Protein 42 2 3

External Ids for TMEM42 Gene

Summaries for TMEM42 Gene

GeneCards Summary for TMEM42 Gene

TMEM42 (Transmembrane Protein 42) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM42 Gene

Genomics for TMEM42 Gene

Genomic Location for TMEM42 Gene

Start:
44,861,869 bp from pter
End:
44,865,670 bp from pter
Size:
3,802 bases
Orientation:
Plus strand

Genomic View for TMEM42 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMEM42 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM42 Gene

Regulatory Elements for TMEM42 Gene

Proteins for TMEM42 Gene

  • Protein details for TMEM42 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q69YG0-TMM42_HUMAN
    Recommended name:
    Transmembrane protein 42
    Protein Accession:
    Q69YG0
    Secondary Accessions:
    • Q8WUQ6

    Protein attributes for TMEM42 Gene

    Size:
    159 amino acids
    Molecular mass:
    16991 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMEM42 Gene

Proteomics data for TMEM42 Gene at MOPED

Post-translational modifications for TMEM42 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TMEM42 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TMEM42 Gene

Domains for TMEM42 Gene

Protein Domains for TMEM42 Gene

ProtoNet:
genes like me logo Genes that share domains with TMEM42: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TMEM42 Gene

Function for TMEM42 Gene

Phenotypes for TMEM42 Gene

GenomeRNAi human phenotypes for TMEM42:
genes like me logo Genes that share phenotypes with TMEM42: view

miRNA for TMEM42 Gene

miRTarBase miRNAs that target TMEM42

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targeting and HOMER Transcription for TMEM42 Gene

Localization for TMEM42 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM42 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TMEM42 Gene COMPARTMENTS Subcellular localization image for TMEM42 gene
Compartment Confidence
plasma membrane 3
nucleus 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for TMEM42 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM42: view

Pathways for TMEM42 Gene

SuperPathways for TMEM42 Gene

No Data Available

Interacting Proteins for TMEM42 Gene

Gene Ontology (GO) - Biological Process for TMEM42 Gene

None

No data available for Pathways by source for TMEM42 Gene

Transcripts for TMEM42 Gene

mRNA/cDNA for TMEM42 Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(85) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TMEM42 Gene

Transmembrane protein 42:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM42 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4a · 4b · 4c · 4d · 4e
SP1: -
SP2:
SP3:
SP4: -
SP5: - -

Relevant External Links for TMEM42 Gene

GeneLoc Exon Structure for
TMEM42
ECgene alternative splicing isoforms for
TMEM42

Expression for TMEM42 Gene

mRNA expression in normal human tissues for TMEM42 Gene

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for TMEM42 Gene

SOURCE GeneReport for Unigene cluster for TMEM42 Gene Hs.646856

genes like me logo Genes that share expressions with TMEM42: view

Orthologs for TMEM42 Gene

This gene was present in the common ancestor of mammals.

Orthologs for TMEM42 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TMEM42 36
  • 99.79 (n)
  • 100 (a)
TMEM42 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia TMEM42 36
  • 88.05 (n)
  • 86.16 (a)
TMEM42 37
  • 86 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TMEM42 36
  • 88.68 (n)
  • 86.16 (a)
TMEM42 37
  • 86 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tmem42 36
  • 83.86 (n)
  • 82.17 (a)
Tmem42 16
Tmem42 37
  • 82 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia TMEM42 37
  • 33 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Tmem42 36
  • 84.29 (n)
  • 84.08 (a)
Species with no ortholog for TMEM42:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TMEM42 Gene

ENSEMBL:
Gene Tree for TMEM42 (if available)
TreeFam:
Gene Tree for TMEM42 (if available)

Paralogs for TMEM42 Gene

No data available for Paralogs for TMEM42 Gene

Variants for TMEM42 Gene

Sequence variations from dbSNP and Humsavar for TMEM42 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs1046827 -- 44,865,322(+) GAGCA(A/G)GCTCT utr-variant-3-prime
rs6808438 -- 44,864,157(+) TGCTG(C/T)CCAGG intron-variant
rs7622843 -- 44,865,736(+) ATCCC(A/G)ATGTG downstream-variant-500B
rs9869037 -- 44,863,802(+) AAATA(A/T)GAACT intron-variant
rs34883405 -- 44,865,838(+) GGTCA(C/T)ACAGG downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for TMEM42 Gene

Variant ID Type Subtype PubMed ID
nsv834675 CNV Gain 17160897
nsv3792 CNV Loss 18451855

Relevant External Links for TMEM42 Gene

HapMap Linkage Disequilibrium report
TMEM42

Disorders for TMEM42 Gene

No disorders were found for TMEM42 Gene.

No data available for UniProtKB/Swiss-Prot for TMEM42 Gene

Publications for TMEM42 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris. (PMID: 24927181) Navarini A.A. … Barker J.N. (Nat Commun 2014) 3
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  4. The full-ORF clone resource of the German cDNA consortium. (PMID: 17974005) Bechtel S. … Schupp I. (BMC Genomics 2007) 4

Products for TMEM42 Gene

Sources for TMEM42 Gene

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