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TMEM41B Gene

protein-coding   GIFtS: 49
GCID: GC11M009302

Transmembrane Protein 41B

  Search for TMEM41B
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Transmembrane Protein 41B1 2
KIAA00333

External Ids:    HGNC: 289481   Entrez Gene: 4400262   Ensembl: ENSG000001664717   UniProtKB: Q5BJD53   

Export aliases for TMEM41B gene to outside databases

Previous GC identifers: GC11M009259 GC11M008974


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TMEM41B Gene:
TMEM41B (transmembrane protein 41B) is a protein-coding gene. An important paralog of this gene is TMEM41A.

UniProtKB/Swiss-Prot: TM41B_HUMAN, Q5BJD5
Function: Required for normal motor neuron development (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000011.9  NC_018922.2  NT_009237.19  
Regulatory elements:
   Regulatory transcription factor binding sites in the TMEM41B gene promoter:
         RFX1   Pax-5   p53   Tal-1   AML1a   GATA-1   Egr-4   E47   E2F-1   NRF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTMEM41B promoter sequence
   Search Chromatin IP Primers for TMEM41B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TMEM41B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11p15.4   Ensembl cytogenetic band:  11p15.4   HGNC cytogenetic band: 11p15.3

TMEM41B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMEM41B gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M009302:  view genomic region     (about GC identifiers)

Start:
9,302,201 bp from pter      End:
9,336,327 bp from pter
Size:
34,127 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: TM41B_HUMAN, Q5BJD5 (See protein sequence)
Recommended Name: Transmembrane protein 41B  
Size: 291 amino acids; 32513 Da
Sequence caution: Sequence=BAA05062.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: D3DQU9 E9PP29 Q15055 Q4G0P0
Alternative splicing: 3 isoforms:  Q5BJD5-1   Q5BJD5-2   Q5BJD5-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TMEM41B: NX_Q5BJD5

Explore proteomics data for TMEM41B at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys100, Lys185
  • Modification sites at PhosphoSitePlus

  • See TMEM41B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001158502.1  NP_055827.1  

    ENSEMBL proteins: 
     ENSP00000299596   ENSP00000431934   ENSP00000433126   ENSP00000435685   ENSP00000436480  

    TMEM41B Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for TMEM41B

     
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    Search for Antibodies for TMEM41B at Abcam
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    Browse Kits and Assays available from EMD Millipore
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    Cloud-Clone Corp. ELISAs for TMEM41B
    Cloud-Clone Corp. CLIAs for TMEM41B
    Search eBioscience for ELISAs for TMEM41B 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR015414 SNARE_assoc

    Graphical View of Domain Structure for InterPro Entry Q5BJD5

    ProtoNet protein and cluster: Q5BJD5

    UniProtKB/Swiss-Prot: TM41B_HUMAN, Q5BJD5
    Similarity: Belongs to the TMEM41 family


    Find genes that share domains with TMEM41B           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TM41B_HUMAN, Q5BJD5
    Function: Required for normal motor neuron development (By similarity)

    Phenotypes:
         2 GenomeRNAi human phenotypes for TMEM41B:

     G0/1 arrest  Increased G1 DNA content 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TMEM41B
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TMEM41B
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TMEM41B

    miRNA
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    miRTarBase miRNAs that target TMEM41B:
    hsa-mir-98-5p (MIRT027755), hsa-mir-26b-5p (MIRT029879), hsa-mir-30a-5p (MIRT005133), hsa-mir-335-5p (MIRT018389)

    Block miRNA regulation of human, mouse, rat TMEM41B using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TMEM41B (see all 28):
    hsa-miR-16-2* hsa-miR-548k hsa-miR-15a hsa-miR-888* hsa-miR-4275 hsa-miR-3605-5p hsa-miR-583 hsa-miR-424
    SwitchGear 3'UTR luciferase reporter plasmidTMEM41B 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for TMEM41B
    Predesigned siRNA for gene silencing in human, mouse, rat TMEM41B

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    Sino Biological Human cDNA Clone for TMEM41B
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM41B

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM41B


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TM41B_HUMAN, Q5BJD5: Membrane; Multi-pass membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane3
    peroxisome1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with TMEM41B           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TMEM41B
    Interactions:

        Search GeneGlobe Interaction Network for TMEM41B

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    Selected Interacting proteins for TMEM41B (Q5BJD53 ENSP000002995964) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PTP4A3O753653, ENSP000003322744I2D: score=1 STRING: ENSP00000332274
    RPS10P467833I2D: score=5 
    CLN3Q132863I2D: score=1 
    UBCENSP000003448184STRING: ENSP00000344818
    ACBD3ENSP000003557774STRING: ENSP00000355777
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007399nervous system development IEA--

    Find genes that share ontologies with TMEM41B           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TMEM41B (TM41B)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for TMEM41B gene (2 alternative transcripts): 
    NM_001165030.2  NM_015012.3  

    Unigene Cluster for TMEM41B:

    Transmembrane protein 41B
    Hs.594563  [show with all ESTs]
    Unigene Representative Sequence: NM_015012
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000299596 ENST00000524543 ENST00000528080(uc001mhm.3 uc001mhn.2)
    ENST00000533867 ENST00000527813 ENST00000533723(uc021qdm.1)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat TMEM41B using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TMEM41B (see all 28):
    hsa-miR-16-2* hsa-miR-548k hsa-miR-15a hsa-miR-888* hsa-miR-4275 hsa-miR-3605-5p hsa-miR-583 hsa-miR-424
    SwitchGear 3'UTR luciferase reporter plasmidTMEM41B 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat TMEM41B
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    GenScript: all cDNA clones in your preferred vector (see all 2): TMEM41B (NM_015012)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM41B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM41B
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for TMEM41B
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMEM41B
      QuantiTect SYBR Green Assays in human, mouse, rat TMEM41B
      QuantiFast Probe-based Assays in human, mouse, rat TMEM41B

    Additional mRNA sequence: 

    AK303339.1 BC064366.1 BC091524.1 D26067.1 NR_028491.2 

    8 DOTS entries:

    DT.91832516  DT.218523  DT.100023639  DT.75132026  DT.100827619  DT.102832550  DT.100653356  DT.100735084 

    Selected AceView cDNA sequences (see all 228):

    BM554990 CR612310 AA677093 AA768142 CR602952 BF197888 BX485830 N53603 
    N79382 BU145525 N54391 BM789626 AA371629 BX956807 AA421070 AA297604 
    CR625188 BX092235 CA487558 N76354 AA370525 Z38820 BQ448029 AW305082 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for TMEM41B    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6
    SP1:                          -                           
    SP2:                                                      


    ECgene alternative splicing isoforms for TMEM41B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TMEM41B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAAATTCAAG
    TMEM41B Expression
    About this image

    TMEM41B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TMEM41B Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.594563
        Custom PCR Arrays for TMEM41B
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM41B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for TMEM41B gene from Selected species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tmem41b1 , 5 transmembrane protein 41B1, 5 87.63(n)1
    90.38(a)1
      7 (57.69 cM)5
    2337241  NM_153525.51  NP_705745.31 
     1099721875 
    chicken
    (Gallus gallus)
    Aves TMEM41B1 transmembrane protein 41B 82.38(n)
    90.42(a)
      423047  NM_001008469.1  NP_001008469.1 
    lizard
    (Anolis carolinensis)
    Reptilia TMEM41B6
    transmembrane protein 41B
    91(a)
    1 ↔ 1
    1(64267555-64278194)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia tmem41b1 transmembrane protein 41B 70.16(n)
    85.2(a)
      549709  NM_001016955.1  NP_001016955.1 
    zebrafish
    (Danio rerio)
    Actinopterygii tmem41b1 transmembrane protein 41B 67.75(n)
    76.17(a)
      561208  NM_001079987.1  NP_001073456.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG84081 CG8408 54.74(n)
    52.85(a)
      32737  NM_132997.2  NP_573225.1 
    worm
    (Caenorhabditis elegans)
    Secernentea tag-1751 tag-175 55.94(n)
    53.48(a)
      183942  NM_063584.1  NP_495985.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT4G177901 AT4G17790 51.1(n)
    41.04(a)
      827501  NM_117889.3  NP_567541.1 
    rice
    (Oryza sativa)
    Liliopsida Os02g06935001 Os02g0693500 48.44(n)
    40(a)
      4330389  NM_001054337.1  NP_001047802.2 


    ENSEMBL Gene Tree for TMEM41B (if available)
    TreeFam Gene Tree for TMEM41B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TMEM41B gene
    TMEM41A2  
    1 SIMAP similar gene for TMEM41B using alignment to 2 protein entries:     TM41B_HUMAN (see all proteins):
    TMEM41A

    Find genes that share paralogs with TMEM41B           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TMEM41B (see all 836)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1481992341,2
    C--9301709(+) CGAACC/TCCTGA 2 -- ds5001 int10--------
    rs1157768211,2
    C,F--9301775(+) CTACCG/ATGCCC 2 -- ds5001 int11Minor allele frequency- A:0.02WA 118
    rs1124716001,2
    C,F--9301780(+) GTGCCC/TGGCCA 2 -- ds5001 int11Minor allele frequency- T:0.50CSA 2
    rs1469157121,2
    --9301781(+) TGCCCA/GGCCAT 2 -- ds5001 int10--------
    rs110422591,2
    C,F--9301812(+) AAATGT/CACATC 2 -- ds5001 int12Minor allele frequency- C:0.10WA NA 238
    rs1864743471,2
    --9301815(+) TGTACA/GTCGAA 2 -- ds5001 int10--------
    rs1913703941,2
    C--9301909(+) GCAGTA/GGCACA 2 -- ds5001 int10--------
    rs1113954411,2
    C,F--9302041(+) GAGACG/AGGGTT 2 -- ds5001 int12Minor allele frequency- A:0.18NA 122
    rs1393473261,2
    C--9302148(+) TGCTCA/GGCCAG 2 -- ds5001 int10--------
    rs743537081,2
    C--9302256(+) ACTAAA/GTGTCA 2 -- ut31 nc-transcript-variant0--------

    HapMap Linkage Disequilibrium report for TMEM41B (9302201 - 9336327 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for TMEM41B (see all 14):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2567694CNV Deletion19546169
    esv1001197CNV Deletion20482838
    esv2744092CNV Deletion23290073
    esv271231CNV Insertion20981092
    esv24655CNV Loss19812545
    nsv508617CNV Loss20534489
    esv32901CNV Loss17666407
    nsv512208CNV Loss21212237
    esv33264CNV Loss17666407
    nsv521969CNV Loss19592680

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TMEM41B
    DNA2.0 Custom Variant and Variant Library Synthesis for TMEM41B

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with TMEM41B           About GenesLikeMe

    Genetic Association Database (GAD): TMEM41B

    Export disorders for TMEM41B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TMEM41B gene, integrated from 10 sources (see all 17):
    (articles sorted by number of sources associating them with TMEM41B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1. (PubMed id 7584026)1, 2, 3 Nomura N.... Tabata S. (DNA Res. 1994)
    2. Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1 (supplement). (PubMed id 7584028)1, 3 Nomura N....Tabata S. (DNA Res. 1994)
    3. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    4. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    5. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    6. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    7. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    8. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (Sci. Signal. 2010)
    9. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (EMBO J. 2009)
    10. Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. (PubMed id 18691976)2 Daub H.... Mann M. (Mol. Cell 2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 440026 HGNC: 28948 AceView: LOC440026 Ensembl:ENSG00000166471 euGenes: HUgn440026
    ECgene: TMEM41B H-InvDB: TMEM41B

    (According to HUGE)
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    HUGE: KIAA0033

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TMEM41B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TMEM41B gene:
    Search GeneIP for patents involving TMEM41B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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