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Aliases for TMEM41A Gene

Aliases for TMEM41A Gene

  • Transmembrane Protein 41A 2 3
  • 2900010K02Rik 3

External Ids for TMEM41A Gene

Summaries for TMEM41A Gene

GeneCards Summary for TMEM41A Gene

TMEM41A (Transmembrane Protein 41A) is a Protein Coding gene. An important paralog of this gene is TMEM41B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM41A Gene

Genomics for TMEM41A Gene

Genomic Location for TMEM41A Gene

Start:
185,476,496 bp from pter
End:
185,499,057 bp from pter
Size:
22,562 bases
Orientation:
Minus strand

Genomic View for TMEM41A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMEM41A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM41A Gene

No data available for Regulatory Elements for TMEM41A Gene

Proteins for TMEM41A Gene

  • Protein details for TMEM41A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96HV5-TM41A_HUMAN
    Recommended name:
    Transmembrane protein 41A
    Protein Accession:
    Q96HV5
    Secondary Accessions:
    • A8K4B3
    • D3DNU2
    • Q6ZMJ0

    Protein attributes for TMEM41A Gene

    Size:
    264 amino acids
    Molecular mass:
    29665 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAD18735.1; Type=Miscellaneous discrepancy; Note=Unlikely isoform. Aberrant splice sites.; Evidence={ECO:0000305};

neXtProt entry for TMEM41A Gene

Proteomics data for TMEM41A Gene at MOPED

Post-translational modifications for TMEM41A Gene

Other Protein References for TMEM41A Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TMEM41A Gene

Domains for TMEM41A Gene

Protein Domains for TMEM41A Gene

ProtoNet:

UniProtKB/Swiss-Prot:

TM41A_HUMAN
Family:
  • Belongs to the TMEM41 family.:
    • Q96HV5
genes like me logo Genes that share domains with TMEM41A: view

No data available for Gene Families for TMEM41A Gene

Function for TMEM41A Gene

Gene Ontology (GO) - Molecular Function for TMEM41A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with TMEM41A: view

Phenotypes for TMEM41A Gene

MGI mutant phenotypes for TMEM41A:
inferred from 1 alleles
genes like me logo Genes that share phenotypes with TMEM41A: view

miRNA for TMEM41A Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for TMEM41A Gene

Localization for TMEM41A Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM41A Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TMEM41A Gene COMPARTMENTS Subcellular localization image for TMEM41A gene
Compartment Confidence
plasma membrane 3

Gene Ontology (GO) - Cellular Components for TMEM41A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM41A: view

Pathways for TMEM41A Gene

SuperPathways for TMEM41A Gene

No Data Available

Gene Ontology (GO) - Biological Process for TMEM41A Gene

None

No data available for Pathways by source for TMEM41A Gene

Transcripts for TMEM41A Gene

Unigene Clusters for TMEM41A Gene

Transmembrane protein 41A:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM41A Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6
SP1: - -
SP2: - - - - -
SP3: -
SP4: -

Relevant External Links for TMEM41A Gene

GeneLoc Exon Structure for
TMEM41A
ECgene alternative splicing isoforms for
TMEM41A

Expression for TMEM41A Gene

mRNA expression in normal human tissues for TMEM41A Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for TMEM41A Gene

SOURCE GeneReport for Unigene cluster for TMEM41A Gene Hs.677570

genes like me logo Genes that share expressions with TMEM41A: view

Orthologs for TMEM41A Gene

This gene was present in the common ancestor of animals.

Orthologs for TMEM41A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TMEM41A 36
  • 99.49 (n)
  • 100 (a)
TMEM41A 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia TMEM41A 36
  • 87.5 (n)
  • 87.88 (a)
TMEM41A 37
  • 88 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TMEM41A 36
  • 89.9 (n)
  • 92.42 (a)
TMEM41A 37
  • 92 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tmem41a 36
  • 84.34 (n)
  • 89.02 (a)
Tmem41a 16
Tmem41a 37
  • 88 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia TMEM41A 37
  • 74 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia TMEM41A 37
  • 77 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Tmem41a 36
  • 85.23 (n)
  • 89.39 (a)
chicken
(Gallus gallus)
Aves TMEM41A 36
  • 70.8 (n)
  • 73.6 (a)
TMEM41A 37
  • 72 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia TMEM41A 37
  • 68 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100492177 36
  • 66 (n)
  • 70.12 (a)
zebrafish
(Danio rerio)
Actinopterygii tmem41aa 36
  • 61.98 (n)
  • 63.5 (a)
tmem41aa 37
  • 58 (a)
OneToMany
tmem41ab 37
  • 59 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea bus-19 36
  • 52.06 (n)
  • 44.69 (a)
bus-19 37
  • 40 (a)
OneToMany
Y71A12C.2 37
  • 41 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 50 (a)
OneToOne
Species with no ortholog for TMEM41A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for TMEM41A Gene

ENSEMBL:
Gene Tree for TMEM41A (if available)
TreeFam:
Gene Tree for TMEM41A (if available)

Paralogs for TMEM41A Gene

Paralogs for TMEM41A Gene

Selected SIMAP similar genes for TMEM41A Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with TMEM41A: view

Variants for TMEM41A Gene

Sequence variations from dbSNP and Humsavar for TMEM41A Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs2119775 -- 185,496,609(+) AAACA(G/T)GCTGG intron-variant
rs2140287 -- 185,499,401(-) TACAT(G/T)TGCTT upstream-variant-2KB
rs5855067 -- 185,493,333(+) GAAAC(-/T)TTAGA intron-variant
rs6779842 -- 185,493,474(+) GATGT(A/G)TGGTG intron-variant
rs6798873 -- 185,494,805(+) GGGTC(C/T)CCAGG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TMEM41A Gene

Variant ID Type Subtype PubMed ID
nsv829818 CNV Loss 17160897

Relevant External Links for TMEM41A Gene

HapMap Linkage Disequilibrium report
TMEM41A

Disorders for TMEM41A Gene

No disorders were found for TMEM41A Gene.

No data available for UniProtKB/Swiss-Prot for TMEM41A Gene

Publications for TMEM41A Gene

  1. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PMID: 21890473) Wagner S.A. … Choudhary C. (Mol. Cell Proteomics 2011) 3
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3

Products for TMEM41A Gene

Sources for TMEM41A Gene

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