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Aliases for TMEM41A Gene

Aliases for TMEM41A Gene

  • Transmembrane Protein 41A 2 3
  • 2900010K02Rik 3

External Ids for TMEM41A Gene

Previous GeneCards Identifiers for TMEM41A Gene

  • GC03M186692
  • GC03M185194
  • GC03M182616

Summaries for TMEM41A Gene

GeneCards Summary for TMEM41A Gene

TMEM41A (Transmembrane Protein 41A) is a Protein Coding gene. An important paralog of this gene is TMEM41B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM41A Gene

Genomics for TMEM41A Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for TMEM41A Gene

185,476,496 bp from pter
185,499,057 bp from pter
22,562 bases
Minus strand

Genomic View for TMEM41A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMEM41A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM41A Gene

No data available for Regulatory Elements for TMEM41A Gene

Proteins for TMEM41A Gene

  • Protein details for TMEM41A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Transmembrane protein 41A
    Protein Accession:
    Secondary Accessions:
    • A8K4B3
    • D3DNU2
    • Q6ZMJ0

    Protein attributes for TMEM41A Gene

    264 amino acids
    Molecular mass:
    29665 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAD18735.1; Type=Miscellaneous discrepancy; Note=Unlikely isoform. Aberrant splice sites.; Evidence={ECO:0000305};

neXtProt entry for TMEM41A Gene

Proteomics data for TMEM41A Gene at MOPED

Post-translational modifications for TMEM41A Gene

Other Protein References for TMEM41A Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

No data available for DME Specific Peptides for TMEM41A Gene

Domains for TMEM41A Gene

Protein Domains for TMEM41A Gene


Suggested Antigen Peptide Sequences for TMEM41A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Q96HV5
  • Belongs to the TMEM41 family.
genes like me logo Genes that share domains with TMEM41A: view

No data available for Gene Families for TMEM41A Gene

Function for TMEM41A Gene

Gene Ontology (GO) - Molecular Function for TMEM41A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with TMEM41A: view

Phenotypes for TMEM41A Gene

MGI mutant phenotypes for TMEM41A:
inferred from 1 alleles
genes like me logo Genes that share phenotypes with TMEM41A: view

Animal Model Products

CRISPR Products

miRNA for TMEM41A Gene

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TMEM41A

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for TMEM41A Gene

Localization for TMEM41A Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM41A Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for TMEM41A Gene COMPARTMENTS Subcellular localization image for TMEM41A gene
Compartment Confidence
plasma membrane 3

Gene Ontology (GO) - Cellular Components for TMEM41A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM41A: view

Pathways for TMEM41A Gene

SuperPathways for TMEM41A Gene

No Data Available

Gene Ontology (GO) - Biological Process for TMEM41A Gene


No data available for Pathways by source for TMEM41A Gene

Transcripts for TMEM41A Gene

Unigene Clusters for TMEM41A Gene

Transmembrane protein 41A:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TMEM41A

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM41A Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6
SP1: - -
SP2: - - - - -
SP3: -
SP4: -

Relevant External Links for TMEM41A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TMEM41A Gene

mRNA expression in normal human tissues for TMEM41A Gene

Protein differential expression in normal tissues for TMEM41A Gene

This gene is overexpressed in Nasal epithelium (54.1).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for TMEM41A Gene

SOURCE GeneReport for Unigene cluster for TMEM41A Gene Hs.677570

genes like me logo Genes that share expressions with TMEM41A: view

Expression partners for TMEM41A Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for TMEM41A Gene

Orthologs for TMEM41A Gene

This gene was present in the common ancestor of animals.

Orthologs for TMEM41A Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia TMEM41A 35
  • 87.5 (n)
  • 87.88 (a)
TMEM41A 36
  • 88 (a)
(Canis familiaris)
Mammalia TMEM41A 35
  • 89.9 (n)
  • 92.42 (a)
TMEM41A 36
  • 92 (a)
(Mus musculus)
Mammalia Tmem41a 35
  • 84.34 (n)
  • 89.02 (a)
Tmem41a 16
Tmem41a 36
  • 88 (a)
(Pan troglodytes)
Mammalia TMEM41A 35
  • 99.49 (n)
  • 100 (a)
TMEM41A 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Tmem41a 35
  • 85.23 (n)
  • 89.39 (a)
(Monodelphis domestica)
Mammalia TMEM41A 36
  • 74 (a)
(Ornithorhynchus anatinus)
Mammalia TMEM41A 36
  • 77 (a)
(Gallus gallus)
Aves TMEM41A 35
  • 70.8 (n)
  • 73.6 (a)
TMEM41A 36
  • 72 (a)
(Anolis carolinensis)
Reptilia TMEM41A 36
  • 68 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100492177 35
  • 66 (n)
  • 70.12 (a)
(Danio rerio)
Actinopterygii tmem41aa 35
  • 61.98 (n)
  • 63.5 (a)
tmem41aa 36
  • 58 (a)
tmem41ab 36
  • 59 (a)
(Caenorhabditis elegans)
Secernentea bus-19 35
  • 52.06 (n)
  • 44.69 (a)
bus-19 36
  • 40 (a)
Y71A12C.2 36
  • 41 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 50 (a)
Species with no ortholog for TMEM41A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for TMEM41A Gene

Gene Tree for TMEM41A (if available)
Gene Tree for TMEM41A (if available)

Paralogs for TMEM41A Gene

Paralogs for TMEM41A Gene

Selected SIMAP similar genes for TMEM41A Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with TMEM41A: view

Variants for TMEM41A Gene

Sequence variations from dbSNP and Humsavar for TMEM41A Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs2119775 -- 185,496,609(+) AAACA(G/T)GCTGG intron-variant
rs2140287 -- 185,499,401(-) TACAT(G/T)TGCTT upstream-variant-2KB
rs5855067 -- 185,493,333(+) GAAAC(-/T)TTAGA intron-variant
rs6779842 -- 185,493,474(+) GATGT(A/G)TGGTG intron-variant
rs6798873 -- 185,494,805(+) GGGTC(C/T)CCAGG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TMEM41A Gene

Variant ID Type Subtype PubMed ID
nsv829818 CNV Loss 17160897

Relevant External Links for TMEM41A Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TMEM41A Gene

Disorders for TMEM41A Gene

No disorders were found for TMEM41A Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for TMEM41A Gene

Publications for TMEM41A Gene

  1. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PMID: 21890473) Wagner S.A. … Choudhary C. (Mol. Cell Proteomics 2011) 3
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3

Products for TMEM41A Gene

Sources for TMEM41A Gene

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