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TMEM39B Gene

protein-coding   GIFtS: 45
GCID: GC01P032537

Transmembrane Protein 39B

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Transmembrane Protein 39B1 2

External Ids:    HGNC: 255101   Entrez Gene: 551162   Ensembl: ENSG000001217757   UniProtKB: Q9GZU33   

Export aliases for TMEM39B gene to outside databases

Previous GC identifers: GC01P032207 GC01P032310 GC01P030655


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TMEM39B Gene:
TMEM39B (transmembrane protein 39B) is a protein-coding gene. An important paralog of this gene is TMEM39A.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NT_032977.10  NC_018912.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the TMEM39B gene promoter:
         RP58   Evi-1   GATA-1   E47   C/EBPalpha   CHOP-10   Cart-1   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTMEM39B promoter sequence
   Search Chromatin IP Primers for TMEM39B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TMEM39B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p35.1   Ensembl cytogenetic band:  1p35.1   HGNC cytogenetic band: 1p35.1

TMEM39B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMEM39B gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P032537:  view genomic region     (about GC identifiers)

Start:
32,537,632 bp from pter      End:
32,568,467 bp from pter
Size:
30,836 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: TM39B_HUMAN, Q9GZU3 (See protein sequence)
Recommended Name: Transmembrane protein 39B  
Size: 492 amino acids; 56274 Da
Secondary accessions: D3DPP4 Q6IA44

Explore the universe of human proteins at neXtProt for TMEM39B: NX_Q9GZU3

Explore proteomics data for TMEM39B at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys234, Lys475
  • Glycosylation2 at Asn8
  • Modification sites at PhosphoSitePlus

  • See TMEM39B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_060526.2  
    ENSEMBL proteins: 
     ENSP00000338165   ENSP00000414616   ENSP00000390889   ENSP00000390057   ENSP00000391719  
     ENSP00000362737  

    TMEM39B Human Recombinant Protein Products:

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    Novus Biologicals TMEM39B Protein
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TMEM39B

     
    Search eBioscience for Proteins for TMEM39B 

     
    antibodies-online proteins for TMEM39B 

     
    Search antibodies-online for peptides for TMEM39B

    TMEM39B Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    Abcam antibodies for TMEM39B (Q9GZU3, Q9GZU3 )
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    antibodies-online antibodies for TMEM39B 

    TMEM39B Assay Products:

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    Cloud-Clone Corp. ELISAs for TMEM39B
    Cloud-Clone Corp. CLIAs for TMEM39B
    Search eBioscience for ELISAs for TMEM39B 
    antibodies-online kits for TMEM39B (8 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR019397 Uncharacterised_TMEM39

    Graphical View of Domain Structure for InterPro Entry Q9GZU3

    ProtoNet protein and cluster: Q9GZU3

    UniProtKB/Swiss-Prot: TM39B_HUMAN, Q9GZU3
    Similarity: Belongs to the TMEM39 family


    Find genes that share domains with TMEM39B           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for TMEM39B

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat TMEM39B using miScript Target Protectors
    5 qRT-PCR Assays for microRNAs that regulate TMEM39B:
    hsa-miR-495 hsa-miR-520d-5p hsa-miR-7-1* hsa-miR-7-2* hsa-miR-524-5p
    SwitchGear 3'UTR luciferase reporter plasmidTMEM39B 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for TMEM39B
    Predesigned siRNA for gene silencing in human, mouse, rat TMEM39B

    Gene Editing
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    DNA2.0 Custom Protein Engineering Service for TMEM39B

    Clone
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    OriGene clones in human, mouse for TMEM39B (see all 7)
    OriGene ORF clones in mouse, rat for TMEM39B
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TMEM39B (NM_018056)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM39B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM39B

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for TMEM39B 
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM39B


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TM39B_HUMAN, Q9GZU3: Membrane; Multi-pass membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane3
    peroxisome2
    cytosol1
    nucleus1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with TMEM39B           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TMEM39B
    Interactions:

        Search GeneGlobe Interaction Network for TMEM39B

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5 Interacting proteins for TMEM39B (Q9GZU32, 3 ENSP000003381654) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NAGSQ8N1592, 3, ENSP000002934044MINT-64900 I2D: score=4 STRING: ENSP00000293404
    UBCP0CG483, ENSP000003448184I2D: score=1 STRING: ENSP00000344818
    IL13RA1ENSP000003607304STRING: ENSP00000360730
    SEC13ENSP000003121224STRING: ENSP00000312122
    SEH1LENSP000003827794STRING: ENSP00000382779
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TMEM39B (TM39B)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for TMEM39B gene: 
    NM_018056.2  

    Unigene Cluster for TMEM39B:

    Transmembrane protein 39B
    Hs.25544  [show with all ESTs]
    Unigene Representative Sequence: AK091861
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000487305 ENST00000336294(uc010ogt.1 uc010ogv.2 uc001buf.4 uc010ogw.2)
    ENST00000438825 ENST00000441402 ENST00000472503 ENST00000468135 ENST00000466321
    ENST00000476968 ENST00000498613 ENST00000456834 ENST00000427288(uc010ogu.1)
    ENST00000373634
    miRNA
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    5 qRT-PCR Assays for microRNAs that regulate TMEM39B:
    hsa-miR-495 hsa-miR-520d-5p hsa-miR-7-1* hsa-miR-7-2* hsa-miR-524-5p
    SwitchGear 3'UTR luciferase reporter plasmidTMEM39B 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for TMEM39B
    Predesigned siRNA for gene silencing in human, mouse, rat TMEM39B
    Clone
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    OriGene clones in human, mouse for TMEM39B (see all 7)
    OriGene ORF clones in mouse, rat for TMEM39B
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TMEM39B (NM_018056)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM39B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM39B
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for TMEM39B
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMEM39B
      QuantiTect SYBR Green Assays in human, mouse, rat TMEM39B
      QuantiFast Probe-based Assays in human, mouse, rat TMEM39B

    Additional mRNA sequence: 

    AK001177.1 AK023331.1 AK055610.1 AK091861.1 AK296653.1 AK298766.1 AK300293.1 AL136695.1 
    BC004364.1 CR457311.1 CR533536.1 

    12 DOTS entries:

    DT.100769615  DT.314535  DT.95073023  DT.86845893  DT.100022435  DT.97776698  DT.121374101  DT.100795292 
    DT.121374060  DT.100022432  DT.100795288  DT.121374148 

    Selected AceView cDNA sequences (see all 171):

    CR601680 AI199141 BE740897 BM695587 CR533536 AK023331 BU509194 BU632256 
    CR613764 BM728998 BQ005647 BQ224814 AK055610 CR590417 AA878262 AI493474 
    AK091861 AI193215 AA410864 BC004364 AW014759 BG398119 CB153330 BX106073 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for TMEM39B (see all 16)    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c · 2d · 2e · 2f · 2g · 2h ^ 3 ^ 4a · 4b ^ 5a · 5b · 5c · 5d ^ 6 ^ 7 ^ 8 ^ 9a · 9b ^ 10a · 10b · 10c ^ 11a · 11b ·
    SP1:        -     -     -     -     -     -     -     -     -     -                                   -     -                                                   
    SP2:                                                  -     -     -                                   -     -                                                   
    SP3:                                                  -     -     -                                   -     -     -     -     -                                 
    SP4:                                                  -     -     -                                   -     -                                                   
    SP5:                                                  -     -     -           -                       -     -                                                   

    ExUns: 11c ^ 12a · 12b ^ 13 ^ 14
    SP1:                              
    SP2:                              
    SP3:                              
    SP4:                              
    SP5:                              


    ECgene alternative splicing isoforms for TMEM39B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TMEM39B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGGCCGCAGG
    TMEM39B Expression
    About this image


    TMEM39B expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Blood (Cardiovascular System)
             Definitive Hematopoietic Stem Cells Definitive Yolk Sac
     
     Eye (Sensory Organs)
             Retina
     
     Yolk Sac (Extraembryonic Tissues)
             Definitive Hematopoietic Stem Cells Definitive Yolk Sac
     
     Testis (Reproductive System)
    TMEM39B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TMEM39B Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.25544
        Custom PCR Arrays for TMEM39B
    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM39B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for TMEM39B gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tmem39b1 , 5 transmembrane protein 39b1, 5 91.87(n)1
    96.14(a)1
      4 (63.31 cM)5
    2307701  NM_199305.11  NP_955009.11 
     1296763555 
    chicken
    (Gallus gallus)
    Aves TMEM39B1 transmembrane protein 39B 77.34(n)
    84.19(a)
      419650  NM_001006313.2  NP_001006313.2 
    lizard
    (Anolis carolinensis)
    Reptilia TMEM39B6
    transmembrane protein 39B
    83(a)
    1 ↔ 1
    GL343308.1(1442456-1513581)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.47122 Xenopus laevis transcribed sequence with weak similarity more 78.59(n)    CF284300.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufi31h122 wufi31h12 74.89(n)   334110  BC045334.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG130166
    --
    29(a)
    1 → many
    2R(10045276-10046939)
    worm
    (Caenorhabditis elegans)
    Secernentea D1007.56
    Protein D1007.5, isoform a
    24(a)
    1 → many
    I(4580692-4583810) WBGene00017003


    ENSEMBL Gene Tree for TMEM39B (if available)
    TreeFam Gene Tree for TMEM39B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TMEM39B gene
    TMEM39A2  
    1 SIMAP similar gene for TMEM39B using alignment to 8 protein entries:     TM39B_HUMAN (see all proteins):
    TMEM39A

    Find genes that share paralogs with TMEM39B           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TMEM39B (see all 626)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs728786501,2
    C,F--32536508(+) CCTCTT/CGGCTG 1 -- us2k12Minor allele frequency- C:0.17CSA WA 120
    rs1154829181,2
    F--32536619(+) AACCCC/TGTCTC 1 -- us2k11Minor allele frequency- T:0.01NA 120
    rs1399601621,2
    C--32536620(+) ACCCCA/GTCTCT 1 -- us2k10--------
    rs1453603761,2
    C--32536669(+) TGCCTA/GTAATC 1 -- us2k10--------
    rs1870729511,2
    --32536946(+) AAAAAA/CACAAA 1 -- us2k10--------
    rs1899155661,2
    --32537005(+) AGGTCA/GAGGTG 1 -- us2k10--------
    rs1812481221,2
    --32537285(+) CATGGA/TGGTGC 1 -- us2k10--------
    rs1506078981,2
    --32537362(+) TTGCAA/GTGAGC 1 -- us2k10--------
    rs743917041,2
    C--32537427(+) AAACAA/GAATAA 1 -- us2k10--------
    rs1498412641,2
    --32537748(+) ATTGAA/GTACTG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for TMEM39B (32537632 - 32568467 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for TMEM39B:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2674125CNV Deletion23128226
    esv25480CNV Loss19812545

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TMEM39B
    DNA2.0 Custom Variant and Variant Library Synthesis for TMEM39B

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TMEM39B gene integrated from 10 sources:
    (articles sorted by number of sources associating them with TMEM39B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (Nature 2006)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    4. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (Genome Res. 2001)
    5. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)
    6. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    7. A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070)1 Stelzl U.... Wanker E.E. (Cell 2005)
    8. Large-scale analysis of the human ubiquitin-related proteome. (PubMed id 16196087)1 Matsumoto M....Nakayama K.I. (Proteomics 2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 55116 HGNC: 25510 AceView: FLJ10315 Ensembl:ENSG00000121775 euGenes: HUgn55116
    ECgene: TMEM39B H-InvDB: TMEM39B

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TMEM39B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TMEM39B gene:
    Search GeneIP for patents involving TMEM39B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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