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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TMEM37 Gene

protein-coding   GIFtS: 43
GCID: GC02P120187

Transmembrane Protein 37

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Transmembrane Protein 371 2 3
Neuronal Voltage-Gated Calcium Channel Gamma-Like Subunit2 3
PR2 3
PR12
Voltage-Dependent Calcium Channel Gamma Subunit-Like Protein2
Voltage-Dependent Calcium Channel Gamma-Like Subunit2

External Ids:    HGNC: 182161   Entrez Gene: 1407382   Ensembl: ENSG000001712277   UniProtKB: Q8WXS43   

Export aliases for TMEM37 gene to outside databases

Previous GC identifers: GC02P119906 GC02P112514


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for TMEM37 Gene: 
TMEM37 (transmembrane protein 37) is a protein-coding gene. Diseases associated with TMEM37 include food allergy, and chronic myeloid leukemia, and among its related super-pathways are MAPK signaling pathway. GO annotations related to this gene include voltage-gated ion channel activity and calcium channel activity.

UniProtKB/Swiss-Prot: CCGL_HUMAN, Q8WXS4
Function: Thought to stabilize the calcium channel in an inactivated (closed) state. Modulates calcium current
when coexpressed with CACNA1G (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NT_022135.16  NC_018913.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TMEM37 gene promoter:
         RORalpha1   FOXI1   HFH-3   AREB6   Elk-1   p53   Brachyury   Nkx2-5   YY1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTMEM37 promoter sequence
   Search SABiosciences Chromatin IP Primers for TMEM37

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TMEM37


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q14.2   Ensembl cytogenetic band:  2q14.2   HGNC cytogenetic band: 2q14.2

TMEM37 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMEM37 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P120187:  view genomic region     (about GC identifiers)

Start:
120,187,477 bp from pter      End:
120,196,096 bp from pter
Size:
8,620 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CCGL_HUMAN, Q8WXS4 (See protein sequence)
Recommended Name: Voltage-dependent calcium channel gamma-like subunit  
Size: 190 amino acids; 20932 Da
Subunit: The L-type calcium channel is composed of five subunits: alpha-1, alpha-2/delta, beta and gamma (By
similarity)
Subcellular location: Membrane; Multi-pass membrane protein (Potential)

Explore the universe of human proteins at neXtProt for TMEM37: NX_Q8WXS4

Explore proteomics data for TMEM37 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8WXS4

  • TMEM37 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    TMEM37 Protein Expression
    REFSEQ proteins: NP_899063.2  
    ENSEMBL proteins: 
     ENSP00000387015   ENSP00000400770   ENSP00000303148  

    Human Recombinant Protein Products for TMEM37: 
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    Novus Biologicals TMEM37 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TMEM37 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral to membrane IEA--

    TMEM37 for ontologies           About GeneDecksing



    TMEM37 Antibody Products: 
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    Cloud-Clone Corp. ELISAs for TMEM37 
    Cloud-Clone Corp. CLIAs for TMEM37


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    ProtoNet protein and cluster: Q8WXS4

    UniProtKB/Swiss-Prot: CCGL_HUMAN, Q8WXS4
    Similarity: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CCGL_HUMAN, Q8WXS4
    Function: Thought to stabilize the calcium channel in an inactivated (closed) state. Modulates calcium current
    when coexpressed with CACNA1G (By similarity)

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005244voltage-gated ion channel activity IEA--
    GO:0005262calcium channel activity IEA--
         
    TMEM37 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for TMEM37 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for TMEM37

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TMEM37 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TMEM37 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TMEM37
    5 QIAGEN miScript miRNA Assays for microRNAs that regulate TMEM37:
    hsa-miR-569 hsa-miR-3688-3p hsa-miR-1207-5p hsa-miR-551b* hsa-miR-181a-2*
    SwitchGear 3'UTR luciferase reporter plasmidTMEM37 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for TMEM37
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TMEM37

    Gene Editing
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    Clone
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    OriGene ORF clones in mouse, rat for TMEM37
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TMEM37 (NM_183240)
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    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM37
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                         Customized lentivirus expression plasmids for stable overexpression of TMEM37 

    Cell Line
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    Search LifeMap BioReagents cell lines for TMEM37
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM37


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for TMEM37 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1MAPK signaling pathway
    MAPK signaling pathway0.50


    1 BioSystems Pathway for TMEM37
        MAPK signaling pathway


    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TMEM37

    STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

    5/8 Interacting proteins for TMEM37 (ENSP000003031484) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TNFRSF14ENSP000003479484STRING: ENSP00000347948
    TNFRSF11AENSP000002694854STRING: ENSP00000269485
    HBP1ENSP000002225744STRING: ENSP00000222574
    MPP3ENSP000003814254STRING: ENSP00000381425
    ORM1ENSP000002593964STRING: ENSP00000259396
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    TMEM37 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TMEM37 (CCGL)

    1 HMDB Compound for TMEM37    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--

    3 Novoseek inferred chemical compound relationships for TMEM37 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    tga 2 92.9 3 15821979 (1), 17369431 (1), 18571510 (1)
    salicylic acid 70.6 16 12897257 (3), 14714866 (2), 19947982 (2), 12468733 (1) (see all 9)
    jasmonic acid 64.3 1 14601670 (1)

    Search CenterWatch for drugs/clinical trials and news about TMEM37 / CCGL

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TMEM37 gene: 
    NM_183240.2  

    Unigene Cluster for TMEM37:

    Transmembrane protein 37
    Hs.26216  [show with all ESTs]
    Unigene Representative Sequence: BC046362
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000409826 ENST00000417645 ENST00000306406(uc002tly.3) ENST00000465296

    miRNA
    Products:
         
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    5 QIAGEN miScript miRNA Assays for microRNAs that regulate TMEM37:
    hsa-miR-569 hsa-miR-3688-3p hsa-miR-1207-5p hsa-miR-551b* hsa-miR-181a-2*
    SwitchGear 3'UTR luciferase reporter plasmidTMEM37 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for TMEM37
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TMEM37
    Clone
    Products:
         
    OriGene clones in human, mouse for TMEM37 (see all 7)
    OriGene ORF clones in mouse, rat for TMEM37
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TMEM37 (NM_183240)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM37
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM37
    Sirion Biotech Customized lentivirus for stable overexpression of TMEM37 
                         Customized lentivirus expression plasmids for stable overexpression of TMEM37 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for TMEM37
    OriGene qSTAR qPCR primer pairs in human, mouse for TMEM37
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TMEM37
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMEM37
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMEM37

    Additional mRNA sequence: 

    AF361356.1 AK026464.1 BC046362.1 

    5 DOTS entries:

    DT.91969316  DT.312618  DT.121028213  DT.92414872  DT.95167038 

    24/51 AceView cDNA sequences (see all 51):

    BM714432 AA846486 AA725153 AI129940 AA894621 AI151077 AA568790 AI582646 
    AK026464 AI080489 BI825302 AI034143 BU608748 BX090423 CD671650 BC046362 
    BM765938 AI288900 CB164031 CB163200 BM724152 BI832565 CB163999 CA502846 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TMEM37 expression in normal human tissues (normalized intensities)      TMEM37 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAGGTGAAGG
    TMEM37 Expression
    About this image


    TMEM37 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/2 selected tissues (see all 2) fully expand
     
     Skeletal Muscle (Muscoskeletal System)    fully expand to see all 2 entries
             Myoblasts Mandibular Arch Muscles
     
     Thyroid (Endocrine System)
             parathyroid gland   

    See TMEM37 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TMEM37

    SOURCE GeneReport for Unigene cluster: Hs.26216
        SABiosciences Custom PCR Arrays for TMEM37
    Primer
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMEM37
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM37

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for TMEM37 gene from 5/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tmem371 , 5 transmembrane protein 371, 5 79.65(n)1
    74.74(a)1
      1 (52.60 cM)5
    1707061  NM_019432.21  NP_062305.11 
     1200673775 
    chicken
    (Gallus gallus)
    Aves TMEM371 transmembrane protein 37 70.39(n)
    62.77(a)
      770956  XM_001234271.2  XP_001234272.1 
    lizard
    (Anolis carolinensis)
    Reptilia TMEM376
    Uncharacterized protein
    54(a)
    1 ↔ 1
    GL343497.1(135753-136343)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.42872 Xenopus laevis transcribed sequence with weak similarity more 69.8(n)    BJ072752.1 
    zebrafish
    (Danio rerio)
    Actinopterygii tmem371 transmembrane protein 37 55.44(n)
    47.06(a)
      406453  NM_213174.2  NP_998339.2 


    ENSEMBL Gene Tree for TMEM37 (if available)
    TreeFam Gene Tree for TMEM37 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/252 SNPs in TMEM37 are shown (see all 252)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1137639671,2
    C,F--120187499(+) TGGGTG/ACAGAT 1 -- us2k11Minor allele frequency- A:0.50CSA 2
    rs1116894691,2
    C,F--120187745(+) GGCCAC/TGGAGG 1 -- us2k13Minor allele frequency- T:0.05CSA WA 122
    rs792731551,2
    C,F--120187746(+) GCCACG/CGAGGG 1 -- us2k12Minor allele frequency- C:0.13CSA WA 120
    rs1438411781,2
    --120187755(+) GGAAGG/TCCCCA 1 -- us2k10--------
    rs796925851,2
    F--120187761(+) CCCCAG/CAGCAG 1 -- us2k11Minor allele frequency- C:0.05WA 118
    rs1153893571,2
    C,F--120187770(+) AGAGAG/AGCACC 1 -- us2k11Minor allele frequency- A:0.03WA 118
    rs802913361,2
    F--120187772(+) AGAGGC/TACCAG 1 -- us2k11Minor allele frequency- T:0.05NA 120
    rs1384033361,2
    --120187830(+) CAAAGC/GCTGGC 1 -- us2k10--------
    rs1159048261,2
    --120187853(+) AGCACA/CAACAT 1 -- us2k10--------
    rs1915319021,2
    --120187954(+) CAAGAA/CCTCAA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for TMEM37 (120187477 - 120196096 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for TMEM37:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv874961CNV Gain21882294
    nsv459119CNV Gain19166990

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing TMEM37
    DNA2.0 Custom Variant and Variant Library Synthesis for TMEM37

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    5 diseases for TMEM37:    About MalaCards
    food allergy    chronic myeloid leukemia    neuronitis    myeloid leukemia
    leukemia


    TMEM37 for disorders           About GeneDecksing


    Export disorders for TMEM37 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TMEM37 gene, integrated from 9 sources (see all 48):
    (articles sorted by number of sources associating them with TMEM37)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Calcium channel gamma subunits provide insights into the evolution of this gene family. (PubMed id 11738816)1, 2 Chu P.-J.... Best P.M. (2001)
    2. The global gene-expression profiles of U-937 human mac rophages treated with Tat peptide and Tat-FITC conjugate. (PubMed id 22632162)1 Lin C.W....Jan M.S. (2012)
    3. Toward an understanding of the protein interaction net work of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (2011)
    4. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W....Wilson R.K. (2005)
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    6. A family of gamma-like calcium channel subunits. (PubMed id 10734232)1 Klugbauer N....Hofmann F. (2000)
    7. Induction of PR-1 accumulation accompanied by runaway cell death in the lsd1 mutant of Arabidopsis is dependent on glutathione levels but independent of the redox state of glutathione. (PubMed id 15574833)9 Senda K. and Ogawa K. (2004)
    8. Genetic interactions of TGA transcription factors in the regulation of pathogenesis-related genes and disease resistance in Arabidopsis. (PubMed id 17369431)9 Kesarwani M....Dong X. (2007)
    9. Structural analysis of the human Golgi-associated plant pathogenesis related protein GAPR-1 implicates dimerization as a regulatory mechanism. (PubMed id 15123429)9 Serrano R.L....Groves M.R. (2004)
    10. Cold activation of a plasma membrane-tethered NAC tra nscription factor induces a pathogen resistance response in Arabidopsis. (PubMed id 19947982)9 Seo P.J....Park C.M. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 140738 HGNC: 18216 AceView: PR1 Ensembl:ENSG00000171227 euGenes: HUgn140738
    ECgene: TMEM37 H-InvDB: TMEM37

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TMEM37 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TMEM37 gene:
    Search GeneIP for patents involving TMEM37

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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    About This Section

     
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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