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Aliases for TMEM31 Gene

Aliases for TMEM31 Gene

  • Transmembrane Protein 31 2 3 5

External Ids for TMEM31 Gene

Previous GeneCards Identifiers for TMEM31 Gene

  • GC0XP101738
  • GC0XP102771
  • GC0XP102852
  • GC0XP102966
  • GC0XP092622

Summaries for TMEM31 Gene

GeneCards Summary for TMEM31 Gene

TMEM31 (Transmembrane Protein 31) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM31 Gene

Genomics for TMEM31 Gene

Regulatory Elements for TMEM31 Gene

Genomic Location for TMEM31 Gene

103,710,909 bp from pter
103,714,032 bp from pter
3,124 bases
Plus strand

Genomic View for TMEM31 Gene

Genes around TMEM31 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TMEM31 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TMEM31 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM31 Gene

Proteins for TMEM31 Gene

  • Protein details for TMEM31 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Transmembrane protein 31
    Protein Accession:
    Secondary Accessions:
    • Q8NHR4

    Protein attributes for TMEM31 Gene

    168 amino acids
    Molecular mass:
    19813 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMEM31 Gene

Proteomics data for TMEM31 Gene at MOPED

Post-translational modifications for TMEM31 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TMEM31 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TMEM31 Gene

Domains & Families for TMEM31 Gene

Protein Domains for TMEM31 Gene


Suggested Antigen Peptide Sequences for TMEM31 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TMEM31: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TMEM31 Gene

Function for TMEM31 Gene

genes like me logo Genes that share phenotypes with TMEM31: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TMEM31 Gene

Localization for TMEM31 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM31 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for TMEM31 Gene COMPARTMENTS Subcellular localization image for TMEM31 gene
Compartment Confidence
plasma membrane 3

No data available for Gene Ontology (GO) - Cellular Components for TMEM31 Gene

Pathways & Interactions for TMEM31 Gene

SuperPathways for TMEM31 Gene

No Data Available

Interacting Proteins for TMEM31 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
Selected Interacting proteins: Q5JXX7-TMM31_HUMAN ENSP00000316940 for TMEM31 Gene via UniProtKB STRING

Gene Ontology (GO) - Biological Process for TMEM31 Gene


No data available for Pathways by source and SIGNOR curated interactions for TMEM31 Gene

Drugs & Compounds for TMEM31 Gene

No Compound Related Data Available

Transcripts for TMEM31 Gene

mRNA/cDNA for TMEM31 Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(21) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TMEM31 Gene

Transmembrane protein 31:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM31 Gene

No ASD Table

Relevant External Links for TMEM31 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TMEM31 Gene

mRNA expression in normal human tissues for TMEM31 Gene

mRNA differential expression in normal tissues according to GTEx for TMEM31 Gene

This gene is overexpressed in Testis (x43.8).

Protein differential expression in normal tissues from HIPED for TMEM31 Gene

This gene is overexpressed in Testis (68.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for TMEM31 Gene

SOURCE GeneReport for Unigene cluster for TMEM31 Gene Hs.98843

genes like me logo Genes that share expression patterns with TMEM31: view

Protein tissue co-expression partners for TMEM31 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for TMEM31 Gene

Orthologs for TMEM31 Gene

This gene was present in the common ancestor of mammals.

Orthologs for TMEM31 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia TMEM31 35
  • 99.8 (n)
  • 100 (a)
TMEM31 36
  • 100 (a)
(Canis familiaris)
Mammalia TMEM31 36
  • 62 (a)
Species with no ortholog for TMEM31:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TMEM31 Gene

Gene Tree for TMEM31 (if available)
Gene Tree for TMEM31 (if available)

Paralogs for TMEM31 Gene

No data available for Paralogs for TMEM31 Gene

Variants for TMEM31 Gene

Variation tolerance for TMEM31 Gene

Residual Variation Intolerance Score: 66.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.64; 13.74% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TMEM31 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for TMEM31 Gene

Disorders for TMEM31 Gene

Relevant External Links for TMEM31

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for TMEM31 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TMEM31 Gene

Publications for TMEM31 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 67
  2. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3

Products for TMEM31 Gene

Sources for TMEM31 Gene

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