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Aliases for TMEM30CP Gene

Aliases for TMEM30CP Gene

  • Transmembrane Protein 30C, Pseudogene 2 3 5
  • Transmembrane Protein 30C 2 4
  • TMEM30C 3 4
  • CDC50C 3 4

External Ids for TMEM30CP Gene

Previous HGNC Symbols for TMEM30CP Gene

  • TMEM30C

Summaries for TMEM30CP Gene

GeneCards Summary for TMEM30CP Gene

TMEM30CP (Transmembrane Protein 30C, Pseudogene) is a Pseudogene.

Additional gene information for TMEM30CP Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM30CP Gene

Genomics for TMEM30CP Gene

Regulatory Elements for TMEM30CP Gene

Enhancers for TMEM30CP Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH03H100072 1.5 Ensembl ENCODE dbSUPER 10.3 -110.5 -110542 5.9 PKNOX1 FOXA2 MLX ARID4B TCF12 SLC30A9 ZNF766 FOS RUNX3 NFYC CMSS1 FILIP1L TBC1D23 TMEM30CP GC03M100078 PIR33357
GH03H100103 1.4 Ensembl ENCODE dbSUPER 10.5 -80.4 -80428 3.3 FOXA2 PKNOX1 NFIB BATF RAD21 YY1 SCRT2 ATF7 RCOR1 RUNX3 TMEM30CP TBC1D23 FILIP1L GC03M100108 GC03M100078
GH03H100068 1.4 Ensembl ENCODE dbSUPER 10.3 -116.7 -116690 0.4 ELF3 ARID4B ZNF2 RAD21 ZNF143 RUNX3 MIXL1 THAP11 ZNF654 USF2 TBC1D23 FILIP1L CMSS1 TMEM30CP GC03M100078 PIR33357
GH03H100149 1.1 Ensembl ENCODE dbSUPER 11.8 -35.1 -35096 2.8 NFIC IRF2 NFIA NFIB CEBPB FEZF1 CEBPG FILIP1L CMSS1 TMEM30CP GC03P100154 GC03M100139
GH03H100156 1 Ensembl ENCODE dbSUPER 11.3 -26.3 -26339 4.8 JUND POLR2A JUN RCOR1 NR2F2 FILIP1L TMEM30CP CMSS1 TBC1D23 COL8A1 LOC105374009 GC03P100154
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around TMEM30CP on UCSC Golden Path with GeneCards custom track

Genomic Locations for TMEM30CP Gene

Genomic Locations for TMEM30CP Gene
chr3:100,185,687-100,211,766
(GRCh38/hg38)
Size:
26,080 bases
Orientation:
Plus strand
chr3:99,904,531-99,913,035
(GRCh37/hg19)

Genomic View for TMEM30CP Gene

Genes around TMEM30CP on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TMEM30CP Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TMEM30CP Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM30CP Gene

Proteins for TMEM30CP Gene

  • Protein details for TMEM30CP Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A0ZSE6-CC50C_HUMAN
    Recommended name:
    Cell cycle control protein 50C
    Protein Accession:
    A0ZSE6

    Protein attributes for TMEM30CP Gene

    Size:
    113 amino acids
    Molecular mass:
    13039 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMEM30CP Gene

Post-translational modifications for TMEM30CP Gene

No Post-translational modifications

No data available for DME Specific Peptides for TMEM30CP Gene

Domains & Families for TMEM30CP Gene

Gene Families for TMEM30CP Gene

Human Protein Atlas (HPA):
  • Predicted secreted proteins

Protein Domains for TMEM30CP Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TMEM30CP Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A0ZSE6

UniProtKB/Swiss-Prot:

CC50C_HUMAN :
  • Belongs to the CDC50/LEM3 family.
Family:
  • Belongs to the CDC50/LEM3 family.
genes like me logo Genes that share domains with TMEM30CP: view

Function for TMEM30CP Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TMEM30CP Gene

Localization for TMEM30CP Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM30CP Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TMEM30CP gene
Compartment Confidence
plasma membrane 3
cytosol 2
extracellular 1
cytoskeleton 1
mitochondrion 1
peroxisome 1
nucleus 1
endoplasmic reticulum 1

Gene Ontology (GO) - Cellular Components for TMEM30CP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM30CP: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for TMEM30CP Gene

Pathways & Interactions for TMEM30CP Gene

SuperPathways for TMEM30CP Gene

No Data Available

Interacting Proteins for TMEM30CP Gene

Gene Ontology (GO) - Biological Process for TMEM30CP Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TMEM30CP Gene

Drugs & Compounds for TMEM30CP Gene

No Compound Related Data Available

Transcripts for TMEM30CP Gene

mRNA/cDNA for TMEM30CP Gene

(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM30CP Gene

No ASD Table

Relevant External Links for TMEM30CP Gene

GeneLoc Exon Structure for
TMEM30CP
ECgene alternative splicing isoforms for
TMEM30CP

Expression for TMEM30CP Gene

NURSA nuclear receptor signaling pathways regulating expression of TMEM30CP Gene:

TMEM30CP

mRNA Expression by UniProt/SwissProt for TMEM30CP Gene:

A0ZSE6-CC50C_HUMAN
Tissue specificity: Specifically expressed in testis.

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TMEM30CP Gene

Orthologs for TMEM30CP Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for TMEM30CP Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TMEM30C 34
  • 64 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TMEM30C 34
  • 20 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tmem30c 34
  • 19 (a)
OneToOne
cow
(Bos Taurus)
Mammalia TMEM30C 34
  • 18 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia TMEM30C 34
  • 17 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia TMEM30C 34
  • 17 (a)
OneToOne
chicken
(Gallus gallus)
Aves TMEM30C 34
  • 13 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii tmem30c 34
  • 11 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG9947 34
  • 9 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea F20C5.4 34
  • 7 (a)
ManyToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes -- 34
  • 6 (a)
ManyToMany
CDC50 34
  • 6 (a)
ManyToMany
LEM3 34
  • 5 (a)
ManyToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 9 (a)
OneToMany
Species where no ortholog for TMEM30CP was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for TMEM30CP Gene

ENSEMBL:
Gene Tree for TMEM30CP (if available)
TreeFam:
Gene Tree for TMEM30CP (if available)

Paralogs for TMEM30CP Gene

No data available for Paralogs for TMEM30CP Gene

Variants for TMEM30CP Gene

Sequence variations from dbSNP and Humsavar for TMEM30CP Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs1000153630 -- 100,188,160(+) TACTC(A/G)AAAAC intron-variant
rs1000318116 -- 100,186,366(+) CCAGG(A/C)TGGTC intron-variant
rs1000416618 -- 100,192,569(+) CTGGA(A/G)AATTT intron-variant
rs1000624754 -- 100,192,845(+) AGGCC(A/G)GGCGC intron-variant
rs1000689741 -- 100,193,517(+) TTTTT(-/TC)TTTTT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TMEM30CP Gene

Variant ID Type Subtype PubMed ID
nsv591148 CNV loss 21841781
nsv523836 CNV gain 19592680
dgv4829n100 CNV loss 25217958

Variation tolerance for TMEM30CP Gene

Gene Damage Index Score: 0.23; 5.25% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TMEM30CP Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TMEM30CP

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TMEM30CP Gene

Disorders for TMEM30CP Gene

Relevant External Links for TMEM30CP

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TMEM30CP
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TMEM30CP

No disorders were found for TMEM30CP Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TMEM30CP Gene

Publications for TMEM30CP Gene

  1. Identification and characterization of CDC50A, CDC50B and CDC50C genes in silico. (PMID: 15375526) Katoh Y … Katoh M (Oncology reports 2004) 2 3 4 60
  2. Aberrant termination of reproduction-related TMEM30C transcripts in the hominoids. (PMID: 17258408) Osada N … Kusuda J (Gene 2007) 3 4 60
  3. The DNA sequence, annotation and analysis of human chromosome 3. (PMID: 16641997) Muzny DM … Gibbs RA (Nature 2006) 4 60

Products for TMEM30CP Gene

Sources for TMEM30CP Gene

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