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Aliases for TMEM30C Gene

Aliases for TMEM30C Gene

  • Transmembrane Protein 30C 2 3 4 5
  • CDC50C 3 4

External Ids for TMEM30C Gene

Previous GeneCards Identifiers for TMEM30C Gene

  • GC03U900581
  • GC03P101389
  • GC03P099904
  • GC03P097272

Summaries for TMEM30C Gene

GeneCards Summary for TMEM30C Gene

TMEM30C (Transmembrane Protein 30C) is a Pseudogene. An important paralog of this gene is TMEM30A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM30C Gene

Genomics for TMEM30C Gene

Regulatory Elements for TMEM30C Gene

Enhancers for TMEM30C Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around TMEM30C on UCSC Golden Path with GeneCards custom track

Genomic Location for TMEM30C Gene

Chromosome:
3
Start:
100,185,824 bp from pter
End:
100,194,191 bp from pter
Size:
8,368 bases
Orientation:
Plus strand

Genomic View for TMEM30C Gene

Genes around TMEM30C on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TMEM30C Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TMEM30C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM30C Gene

Proteins for TMEM30C Gene

  • Protein details for TMEM30C Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A0ZSE6-CC50C_HUMAN
    Recommended name:
    Cell cycle control protein 50C
    Protein Accession:
    A0ZSE6

    Protein attributes for TMEM30C Gene

    Size:
    113 amino acids
    Molecular mass:
    13039 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMEM30C Gene

Proteomics data for TMEM30C Gene at MOPED

Post-translational modifications for TMEM30C Gene

Other Protein References for TMEM30C Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for TMEM30C Gene

Domains & Families for TMEM30C Gene

Protein Domains for TMEM30C Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TMEM30C Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A0ZSE6

UniProtKB/Swiss-Prot:

CC50C_HUMAN :
  • Belongs to the CDC50/LEM3 family.
Family:
  • Belongs to the CDC50/LEM3 family.
genes like me logo Genes that share domains with TMEM30C: view

No data available for Gene Families for TMEM30C Gene

Function for TMEM30C Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TMEM30C Gene

Localization for TMEM30C Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM30C Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TMEM30C Gene COMPARTMENTS Subcellular localization image for TMEM30C gene
Compartment Confidence
plasma membrane 3
cytosol 2
cytoskeleton 1
endoplasmic reticulum 1
extracellular 1
mitochondrion 1
nucleus 1
peroxisome 1

No data available for Gene Ontology (GO) - Cellular Components for TMEM30C Gene

Pathways & Interactions for TMEM30C Gene

SuperPathways for TMEM30C Gene

No Data Available

Interacting Proteins for TMEM30C Gene

Gene Ontology (GO) - Biological Process for TMEM30C Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TMEM30C Gene

Drugs & Compounds for TMEM30C Gene

No Compound Related Data Available

Transcripts for TMEM30C Gene

mRNA/cDNA for TMEM30C Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM30C Gene

No ASD Table

Relevant External Links for TMEM30C Gene

GeneLoc Exon Structure for
TMEM30C
ECgene alternative splicing isoforms for
TMEM30C

Expression for TMEM30C Gene

mRNA expression in normal human tissues for TMEM30C Gene

mRNA differential expression in normal tissues according to GTEx for TMEM30C Gene

This gene is overexpressed in Testis (x37.9).

SOURCE GeneReport for Unigene cluster for TMEM30C Gene Hs.652353

mRNA Expression by UniProt/SwissProt for TMEM30C Gene

A0ZSE6-CC50C_HUMAN
Tissue specificity: Specifically expressed in testis.
genes like me logo Genes that share expression patterns with TMEM30C: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression and Protein tissue co-expression partners for TMEM30C Gene

Orthologs for TMEM30C Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for TMEM30C Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia TMEM30C 36
  • 18 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TMEM30C 36
  • 20 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia TMEM30C 36
  • 17 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tmem30c 36
  • 19 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia TMEM30C 36
  • 17 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia TMEM30C 36
  • 64 (a)
OneToOne
chicken
(Gallus gallus)
Aves TMEM30C 36
  • 13 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii tmem30c 36
  • 11 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG9947 36
  • 9 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea F20C5.4 36
  • 7 (a)
ManyToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes -- 36
  • 6 (a)
ManyToMany
CDC50 36
  • 6 (a)
ManyToMany
LEM3 36
  • 5 (a)
ManyToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 9 (a)
OneToMany
Species with no ortholog for TMEM30C:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for TMEM30C Gene

ENSEMBL:
Gene Tree for TMEM30C (if available)
TreeFam:
Gene Tree for TMEM30C (if available)

Paralogs for TMEM30C Gene

Paralogs for TMEM30C Gene

(1) SIMAP similar genes for TMEM30C Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with TMEM30C: view

Variants for TMEM30C Gene

Sequence variations from dbSNP and Humsavar for TMEM30C Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs1017967 -- 100,186,959(-) TTCTT(G/T)CAGAG intron-variant
rs1872609 -- 100,187,735(-) TTTAC(A/G)TATAA intron-variant
rs1214285 -- 100,191,364(-) gggca(C/G)caaga intron-variant
rs9816538 -- 100,189,080(+) TTCTC(C/T)GCACT intron-variant
rs7620267 -- 100,192,979(+) TAGCC(A/G)GGTGT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TMEM30C Gene

Variant ID Type Subtype PubMed ID
nsv523836 CNV Gain 19592680

Variation tolerance for TMEM30C Gene

Gene Damage Index Score: 0.23; 5.25% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for TMEM30C Gene

Disorders for TMEM30C Gene

Relevant External Links for TMEM30C

Genetic Association Database (GAD)
TMEM30C
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TMEM30C

No disorders were found for TMEM30C Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TMEM30C Gene

Publications for TMEM30C Gene

  1. Identification and characterization of CDC50A, CDC50B and CDC50C genes in silico. (PMID: 15375526) Katoh Y. … Katoh M. (Oncol. Rep. 2004) 2 3 4 67
  2. Aberrant termination of reproduction-related TMEM30C transcripts in the hominoids. (PMID: 17258408) Osada N. … Kusuda J. (Gene 2007) 3

Products for TMEM30C Gene

Sources for TMEM30C Gene

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