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Aliases for TMEM30C Gene

Aliases for TMEM30C Gene

  • Transmembrane Protein 30C 2 3 4
  • CDC50C 3 4 6

External Ids for TMEM30C Gene

Previous GeneCards Identifiers for TMEM30C Gene

  • GC03U900581
  • GC03P101389
  • GC03P099904
  • GC03P097272

Summaries for TMEM30C Gene

GeneCards Summary for TMEM30C Gene

TMEM30C (Transmembrane Protein 30C) is a Pseudogene. An important paralog of this gene is TMEM30B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM30C Gene

Genomics for TMEM30C Gene

Regulatory Elements for TMEM30C Gene

Genomic Location for TMEM30C Gene

Start:
100,185,824 bp from pter
End:
100,194,191 bp from pter
Size:
8,368 bases
Orientation:
Plus strand

Genomic View for TMEM30C Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMEM30C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM30C Gene

Proteins for TMEM30C Gene

  • Protein details for TMEM30C Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A0ZSE6-CC50C_HUMAN
    Recommended name:
    Cell cycle control protein 50C
    Protein Accession:
    A0ZSE6
    Secondary Accessions:

    Protein attributes for TMEM30C Gene

    Size:
    113 amino acids
    Molecular mass:
    13039 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMEM30C Gene

Proteomics data for TMEM30C Gene at MOPED

Post-translational modifications for TMEM30C Gene

Other Protein References for TMEM30C Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for TMEM30C Gene

Domains for TMEM30C Gene

Protein Domains for TMEM30C Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TMEM30C Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A0ZSE6

UniProtKB/Swiss-Prot:

CC50C_HUMAN :
  • A0ZSE6
Family:
  • Belongs to the CDC50/LEM3 family.
genes like me logo Genes that share domains with TMEM30C: view

No data available for Gene Families for TMEM30C Gene

Function for TMEM30C Gene

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TMEM30C

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TMEM30C Gene

Localization for TMEM30C Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM30C Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TMEM30C Gene COMPARTMENTS Subcellular localization image for TMEM30C gene
Compartment Confidence
plasma membrane 3
cytosol 2
cytoskeleton 1
endoplasmic reticulum 1
extracellular 1
mitochondrion 1
nucleus 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for TMEM30C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM30C: view

Pathways for TMEM30C Gene

SuperPathways for TMEM30C Gene

No Data Available

Interacting Proteins for TMEM30C Gene

Gene Ontology (GO) - Biological Process for TMEM30C Gene

None

No data available for Pathways by source for TMEM30C Gene

Transcripts for TMEM30C Gene

mRNA/cDNA for TMEM30C Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TMEM30C

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM30C Gene

No ASD Table

Relevant External Links for TMEM30C Gene

GeneLoc Exon Structure for
TMEM30C
ECgene alternative splicing isoforms for
TMEM30C

Expression for TMEM30C Gene

mRNA expression in normal human tissues for TMEM30C Gene

mRNA differential expression in normal tissues according to GTEx for TMEM30C Gene

This gene is overexpressed in Testis (37.9).

SOURCE GeneReport for Unigene cluster for TMEM30C Gene Hs.652353

mRNA Expression by UniProt/SwissProt for TMEM30C Gene

A0ZSE6-CC50C_HUMAN
Tissue specificity: Specifically expressed in testis.
genes like me logo Genes that share expressions with TMEM30C: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and Protein expression for TMEM30C Gene

Orthologs for TMEM30C Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for TMEM30C Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TMEM30C 36
  • 64 (a)
OneToOne
cow
(Bos Taurus)
Mammalia TMEM30C 36
  • 18 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TMEM30C 36
  • 20 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tmem30c 16
Tmem30c 36
  • 19 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia TMEM30C 36
  • 17 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia TMEM30C 36
  • 17 (a)
OneToOne
chicken
(Gallus gallus)
Aves TMEM30C 36
  • 13 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii tmem30c 36
  • 11 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG9947 36
  • 9 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea F20C5.4 36
  • 7 (a)
ManyToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes -- 36
  • 6 (a)
ManyToMany
CDC50 36
  • 6 (a)
ManyToMany
LEM3 36
  • 5 (a)
ManyToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 9 (a)
OneToMany
Species with no ortholog for TMEM30C:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for TMEM30C Gene

ENSEMBL:
Gene Tree for TMEM30C (if available)
TreeFam:
Gene Tree for TMEM30C (if available)

Paralogs for TMEM30C Gene

Paralogs for TMEM30C Gene

Selected SIMAP similar genes for TMEM30C Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with TMEM30C: view

Variants for TMEM30C Gene

Sequence variations from dbSNP and Humsavar for TMEM30C Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs1017967 -- 100,186,959(-) TTCTT(G/T)CAGAG intron-variant
rs1214285 -- 100,191,364(-) gggca(C/G)caaga intron-variant
rs1684234 -- 100,191,423(-) CTTTA(G/T)CATTC intron-variant
rs1684236 -- 100,188,700(-) GGGTT(A/C)TAGTT intron-variant
rs1684237 -- 100,187,600(-) GAAAA(C/G)ACATT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TMEM30C Gene

Variant ID Type Subtype PubMed ID
nsv523836 CNV Gain 19592680

Relevant External Links for TMEM30C Gene

HapMap Linkage Disequilibrium report
TMEM30C

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TMEM30C Gene

Disorders for TMEM30C Gene

Relevant External Links for TMEM30C

Genetic Association Database (GAD)
TMEM30C
genes like me logo Genes that share disorders with TMEM30C: view

No data available for UniProtKB/Swiss-Prot for TMEM30C Gene

Publications for TMEM30C Gene

  1. Identification and characterization of CDC50A, CDC50B and CDC50C genes in silico. (PMID: 15375526) Katoh Y. … Katoh M. (Oncol. Rep. 2004) 2 3 4
  2. Aberrant termination of reproduction-related TMEM30C transcripts in the hominoids. (PMID: 17258408) Osada N. … Kusuda J. (Gene 2007) 3 4
  3. Framingham Heart Study 100K Project: genome-wide associations for blood pressure and arterial stiffness. (PMID: 17903302) Levy D. … Mitchell G.F. (BMC Med. Genet. 2007) 48
  4. The DNA sequence, annotation and analysis of human chromosome 3. (PMID: 16641997) Muzny D.M. … Gibbs R.A. (Nature 2006) 4

Products for TMEM30C Gene

  • antibodies-online proteins for TMEM30C
  • antibodies-online antibodies for TMEM30C
  • antibodies-online kits for TMEM30C

Sources for TMEM30C Gene

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