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TMEM30B Gene

protein-coding   GIFtS: 50
GCID: GC14M061744

Transmembrane Protein 30B

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Transmembrane Protein 30B1 2 3
CDC50B2 3 5
Cell Cycle Control Protein 50B2

External Ids:    HGNC: 272541   Entrez Gene: 1612912   Ensembl: ENSG000001821077   OMIM: 6110295   UniProtKB: Q3MIR43   

Export aliases for TMEM30B gene to outside databases

Previous GC identifers: GC14M059735 GC14M060814 GC14M041907


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TMEM30B Gene:
TMEM30B (transmembrane protein 30B) is a protein-coding gene. Diseases associated with TMEM30B include malignant peritoneal mesothelioma, and intrahepatic cholestasis. An important paralog of this gene is TMEM30C.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000014.9  NC_018925.2  NT_026437.13  
Regulatory elements:
   Regulatory transcription factor binding sites in the TMEM30B gene promoter:
         Pax-5   NRSF form 1   POU3F2 (N-Oct-5a)   POU3F2 (N-Oct-5b)   NRSF form 2   POU3F2   YY1   C/EBPalpha   ATF6   Hlf   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for TMEM30B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TMEM30B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q23.1   Ensembl cytogenetic band:  14q23.1   HGNC cytogenetic band: 14q23.1

TMEM30B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMEM30B gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14M061744:  view genomic region     (about GC identifiers)

Start:
61,744,088 bp from pter      End:
61,748,558 bp from pter
Size:
4,471 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: CC50B_HUMAN, Q3MIR4 (See protein sequence)
Recommended Name: Cell cycle control protein 50B  
Size: 351 amino acids; 38941 Da
Secondary accessions: B3KR84 Q14D00

Explore the universe of human proteins at neXtProt for TMEM30B: NX_Q3MIR4

Explore proteomics data for TMEM30B at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn75, Asn213, Asn286

  • See TMEM30B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_001017970.1  
    ENSEMBL proteins: 
     ENSP00000450842   ENSP00000347930  

    TMEM30B Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
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    Novus Biologicals TMEM30B Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TMEM30B

    TMEM30B Antibody Products:

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    Novus Biologicals TMEM30B Antibodies
    Abcam antibodies for TMEM30B
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    ThermoFisher Antibody for TMEM30B
    LSBio Antibodies in human, mouse, rat for TMEM30B

    TMEM30B Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    GenScript Custom Assay Services for TMEM30B
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for TMEM30B
    Cloud-Clone Corp. CLIAs for TMEM30B


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR005045 DUF284_TM_euk

    Graphical View of Domain Structure for InterPro Entry Q3MIR4

    ProtoNet protein and cluster: Q3MIR4

    1 Blocks protein domain: IPB005045 Eukaryotic protein of unknown function DUF284

    UniProtKB/Swiss-Prot: CC50B_HUMAN, Q3MIR4
    Similarity: Belongs to the CDC50/LEM3 family


    TMEM30B for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
         
    TMEM30B for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for TMEM30B:
     Synthetic lethal with Ras 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TMEM30B
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TMEM30B

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TMEM30B
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TMEM30B

    miRNA
    Products:
        
    miRTarBase miRNAs that target TMEM30B:
    hsa-mir-26b-5p (MIRT030135), hsa-mir-335-5p (MIRT018891)

    Block miRNA regulation of human, mouse, rat TMEM30B using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TMEM30B (see all 18):
    hsa-miR-579 hsa-miR-607 hsa-miR-1205 hsa-miR-3692 hsa-miR-298 hsa-miR-3658 hsa-miR-7-1* hsa-miR-186
    SwitchGear 3'UTR luciferase reporter plasmidTMEM30B 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for TMEM30B
    Predesigned siRNA for gene silencing in human, mouse, rat TMEM30B

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for TMEM30B

    Clone
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    OriGene clones in human, mouse for TMEM30B (see all 7)
    OriGene ORF clones in mouse, rat for TMEM30B
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TMEM30B (NM_001017970)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM30B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM30B

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for TMEM30B 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM30B


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CC50B_HUMAN, Q3MIR4: Membrane; Multi-pass membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane3
    cytoskeleton1
    endoplasmic reticulum1
    nucleus1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016020membrane ----
    GO:0016021integral component of membrane IEA--

    TMEM30B for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TMEM30B
    Interactions:

        Search GeneGlobe Interaction Network for TMEM30B

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for TMEM30B (Q3MIR43 ENSP000003479304) via UniProtKB, MINT, STRING, and/or I2D (see all 90)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ENSG00000206286Q8N1B43, ENSP000003726974I2D: score=1 STRING: ENSP00000372697
    ENSG00000224455Q8N1B43, ENSP000004040164I2D: score=1 STRING: ENSP00000404016
    ENSG00000225590Q8N1B43, ENSP000003911974I2D: score=1 STRING: ENSP00000391197
    ENSG00000228425Q8N1B43, ENSP000003908314I2D: score=1 STRING: ENSP00000390831
    ENSG00000236014Q8N1B43, ENSP000004069884I2D: score=1 STRING: ENSP00000406988
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0070863positive regulation of protein exit from endoplasmic reticulum IDA--

    TMEM30B for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TMEM30B (CC50B)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for TMEM30B gene: 
    NM_001017970.2  

    Unigene Cluster for TMEM30B:

    Transmembrane protein 30B
    Hs.146180  [show with all ESTs]
    Unigene Representative Sequence: NM_001017970
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000555868(uc001xfl.3) ENST00000557163 ENST00000554497 ENST00000355702

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat TMEM30B using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TMEM30B (see all 18):
    hsa-miR-579 hsa-miR-607 hsa-miR-1205 hsa-miR-3692 hsa-miR-298 hsa-miR-3658 hsa-miR-7-1* hsa-miR-186
    SwitchGear 3'UTR luciferase reporter plasmidTMEM30B 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for TMEM30B
    Predesigned siRNA for gene silencing in human, mouse, rat TMEM30B
    Clone
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    OriGene clones in human, mouse for TMEM30B (see all 7)
    OriGene ORF clones in mouse, rat for TMEM30B
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TMEM30B (NM_001017970)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM30B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM30B
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for TMEM30B
    OriGene qSTAR qPCR primer pairs in human, mouse for TMEM30B
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMEM30B
      QuantiTect SYBR Green Assays in human, mouse, rat TMEM30B
      QuantiFast Probe-based Assays in human, mouse, rat TMEM30B

    Additional mRNA sequence: 

    AK309281.1 AL080078.1 BC033845.1 BC101726.1 BC113559.1 

    4 DOTS entries:

    DT.441292  DT.429626  DT.95268786  DT.95082156 

    Selected AceView cDNA sequences (see all 112):

    AI343269 AA344230 AI701446 AI697010 AW271437 AA975312 AI568945 AI261370 
    AI420342 BF056190 CA950865 BF222257 BM818997 AW001762 AI814620 BF476194 
    BF590065 AI935293 AI522020 BE327052 BE504706 BF448930 AX746825 BE465272 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TMEM30B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    TMEM30B Expression
    About this image


    TMEM30B expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 9) fully expand
     
     Kidney (Urinary System)    fully expand to see all 3 entries
             Ureteric Bud Cells Ureteric Bud
             Renal Collecting Duct System
     
     Bone (Muscoskeletal System)    fully expand to see all 2 entries
             Mesenchymal Condensate Cells Zeugopod
             Maxillary Process
     
     Limb (Muscoskeletal System)    fully expand to see all 2 entries
             Limb Muscle Progenitor Cells Forelimb Myotome
     
     Cartilage (Muscoskeletal System)
             Mesenchymal Condensate Cells Zeugopod
     
     Testis (Reproductive System)
             Sertoli cells Seminiferous Tubules
    TMEM30B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TMEM30B Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.146180
        Custom PCR Arrays for TMEM30B
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    QuantiFast Probe-based Assays in human, mouse, rat TMEM30B
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM30B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for TMEM30B gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tmem30b1 , 5 transmembrane protein 30B1, 5 91.03(n)1
    90.64(a)1
      12 (30.65 cM)5
    2382571  NM_178715.31  NP_848830.11 
     735431145 
    lizard
    (Anolis carolinensis)
    Reptilia TMEM30B6
    transmembrane protein 30B
    54(a)
    1 ↔ 1
    LGc(6883422-6884756)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia tmem30b1 transmembrane protein 30B 55.45(n)
    61.11(a)
      734012  NM_001045712.1  NP_001039177.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc:919081 zgc:91908 56.75(n)
    57.98(a)
      431726  NM_001002179.1  NP_001002179.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG99476
    --
    45(a)
    1 → many
    X(16333180-16335313)
    worm
    (Caenorhabditis elegans)
    Secernentea chat-16
    Protein CHAT-1, isoform b
    41(a)
    many ↔ many
    IV(4447331-4449896) WBGene00019946
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes CDC50(YCR094W)4 Endosomal protein that interacts with phospholipid more   --   3(286762-287937) 850456  NP_010018.1 


    ENSEMBL Gene Tree for TMEM30B (if available)
    TreeFam Gene Tree for TMEM30B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TMEM30B gene
    TMEM30C2  TMEM30A2  
    1 SIMAP similar gene for TMEM30B using alignment to 1 protein entry:     CC50B_HUMAN:
    TMEM30A

    TMEM30B for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TMEM30B (see all 154)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 14 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1813318821,2
    --61743591(+) TATTAC/GTCTGT 1 -- ds50010--------
    rs1855532071,2
    --61743593(+) TTAGTC/TTGTCT 1 -- ds50010--------
    rs1501676871,2
    C--61743659(+) CACTTC/TGGGAG 1 -- ds50010--------
    rs1386290911,2
    --61743728(+) GAAACC/GCCATC 1 -- ds50010--------
    rs1427059211,2
    --61743764(+) CTGGGC/TGTGGT 1 -- ds50010--------
    rs1915984741,2
    --61743790(+) TCTCAG/TCTACT 1 -- ds50010--------
    rs1818809131,2
    --61743843(+) AGGTTA/GCAGTG 1 -- ds50010--------
    rs23518051,2
    C,F,A--61743853(+) gagccG/Aaggtt 1 -- ds50011Minor allele frequency- A:0.50WA 2
    rs1873933151,2
    --61743890(+) ACTCCA/GGCCTG 1 -- ds50010--------
    rs1116051891,2
    C,F--61744030(+) TTAACG/CATCTG 1 -- ds50011Minor allele frequency- C:0.50CSA 2

    HapMap Linkage Disequilibrium report for TMEM30B (61744088 - 61748558 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for TMEM30B:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv902005CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TMEM30B
    DNA2.0 Custom Variant and Variant Library Synthesis for TMEM30B

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611029    OMIM disorders: --

    7 diseases for TMEM30B:    
    About MalaCards
    malignant peritoneal mesothelioma    intrahepatic cholestasis    cholestasis    meningioma
    peritonitis    malaria    obesity

    2 diseases from the University of Copenhagen DISEASES database for TMEM30B:
    Malignant peritoneal mesothelioma     Meningioma

    TMEM30B for disorders           About GeneDecksing


    Export disorders for TMEM30B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TMEM30B gene integrated from 10 sources:
    (articles sorted by number of sources associating them with TMEM30B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification and characterization of CDC50A, CDC50B and CDC50C genes in silico. (PubMed id 15375526)1, 2, 3, 9 Katoh Y. and Katoh M. (Oncol. Rep. 2004)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PubMed id 23251661)1 Comuzzie A.G....Butte N.F. (PLoS ONE 2012)
    5. ATP9B, a P4-ATPase (a putative aminophospholipid translocase), localizes to the trans-Golgi network in a CDC50 protein-independent manner. (PubMed id 21914794)1 Takatsu H.... Shin H.W. (J. Biol. Chem. 2011)
    6. Differential expression profiling analyses identifies downregulation of 1p, 6q, and 14q genes and overexpression of 6p histone cluster 1 genes as markers of recurrence in meningiomas. (PubMed id 20685720)1 PAcrez-MagA!n E....MelAcndez B. (Neuro-oncology 2010)
    7. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 161291 HGNC: 27254 AceView: TMEM30B Ensembl:ENSG00000182107 euGenes: HUgn161291
    ECgene: TMEM30B H-InvDB: TMEM30B

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TMEM30B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TMEM30B gene:
    Search GeneIP for patents involving TMEM30B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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