Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TMEM30B Gene

protein-coding   GIFtS: 48
GCID: GC14M061744

transmembrane protein 30B
 Explore 4 diseases affiliated with
TMEM30B via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for TMEM30B    

Aliases
for TMEM30B gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Transmembrane Protein 30B1 2 3
CDC50B1 2 3 5
Cell Cycle Control Protein 50B2

External Ids:    HGNC: 272541   Entrez Gene: 1612912   Ensembl: ENSG000001821077   OMIM: 6110295   UniProtKB: Q3MIR43   

Export aliases for TMEM30B gene to outside databases

Previous GC identifers: GC14M059735 GC14M060814 GC14M041907


Summaries
for TMEM30B gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
  --

Genomic Views
for TMEM30B gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000014.8  NC_018925.1  NT_026437.12  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TMEM30B gene promoter:
         Pax-5   NRSF form 1   POU3F2 (N-Oct-5a)   POU3F2 (N-Oct-5b)   NRSF form 2   POU3F2   YY1   C/EBPalpha   ATF6   Hlf   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for TMEM30B

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TMEM30B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q23.1   Ensembl cytogenetic band:  14q23.1   HGNC cytogenetic band: 14q23.1

TMEM30B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMEM30B gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14M061744:  view genomic region     (about GC identifiers)

Start:
 61,744,088 bp from pter      End:
 61,748,558 bp from pter
Size:
 4,471 bases      Orientation:
 minus strand

Proteins
for TMEM30B gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: CC50B_HUMAN, Q3MIR4 (See protein sequence)
Recommended Name: Cell cycle control protein 50B  
Size: 351 amino acids; 38941 Da
Subcellular location: Membrane; Multi-pass membrane protein (Potential)
Secondary accessions: B3KR84 Q14D00

Explore the universe of human proteins at neXtProt for TMEM30B: NX_Q3MIR4

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q3MIR4

    • TMEM30B Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_001017970.1  
    ENSEMBL proteins: 
     ENSP00000450842   ENSP00000347930  

    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate: TMEM30B
    OriGene Custom Protein Services for TMEM30B 
    GenScript Custom Purified and Recombinant Proteins Services for TMEM30B
    Novus Biologicals TMEM30B Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for TMEM30B

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral to membrane IEA--


    TMEM30B for ontologies           About GeneDecksing



    TMEM30B Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for TMEM30B 
    GenScript Custom Superior Antibodies Services for TMEM30B
    Novus Biologicals TMEM30B Antibodies
    Search for Antibodies for TMEM30B at Abcam  
    Uscn Antibodies for TMEM30B
    ThermoFisher Antibody for TMEM30B

    Assay Products for TMEM30B: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Immunoassay Development
    Browse OriGene Fluorogenic Cell Assay Kits
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for TMEM30B
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for TMEM30B

    Protein Domains /
    Families
    for TMEM30B gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    TMEM30B for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR005045 DUF284_TM_euk

    Graphical View of Domain Structure for InterPro Entry Q3MIR4

    ProtoNet protein and cluster: Q3MIR4

    1 Blocks protein family: IPB005045 Eukaryotic protein of unknown function DUF284

    UniProtKB/Swiss-Prot: CC50B_HUMAN, Q3MIR4
    Similarity: Belongs to the CDC50/LEM3 family


    Function
    for TMEM30B gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    miRNA
    Products:            		 OriGene 3'-UTR Clone: TMEM30B
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TMEM30B
    8/18 QIAGEN miScript miRNA Assays for microRNAs that regulate TMEM30B (see all 18):
    hsa-miR-579 hsa-miR-607 hsa-miR-1205 hsa-miR-3692 hsa-miR-298 hsa-miR-3658 hsa-miR-7-1* hsa-miR-186
    SwitchGear 3'UTR luciferase reporter plasmid: TMEM30B 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TMEM30B (see all 7)
    OriGene shRNA RFP: TMEM30B
    OriGene siRNA: TMEM30B
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TMEM30B

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for TMEM30B

    Clone
    Products:             		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TMEM30B (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TMEM30B
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: TMEM30B (NM_001017970)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM30B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM30B 

    Cell Line
    Products:             		GenScript Custom overexpressing Cell Line Services for TMEM30B
    Search LifeMap BioReagents cell lines for TMEM30B

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM30B

    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--


    TMEM30B for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for TMEM30B:
     Synthetic lethal with Ras 


    Pathways & Interactions
    for TMEM30B gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TMEM30B

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5/40 Interacting proteins for TMEM30B (Q3MIR43 ENSP000003479304) via UniProtKB, MINT, STRING, and/or I2D (see all 40)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ATP8A1Q9Y2Q03, ENSP000003710844I2D: score=2 STRING: ENSP00000371084
    SC5DLO758453, ENSP000002640274I2D: score=1 STRING: ENSP00000264027
    HSP90AA1P079003I2D: score=2 
    ACTBP607093I2D: score=1 
    ACTG1P632613I2D: score=1 
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0070863positive regulation of protein exit from endoplasmic reticulum IDA--


    TMEM30B for ontologies           About GeneDecksing



    Drugs & Compounds
    for TMEM30B gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TMEM30B
    Search CenterWatch for drugs/clinical trials and news about TMEM30B / CC50B 

    Transcripts
    for TMEM30B gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for TMEM30B gene: 
    NM_001017970.2  

    Unigene Cluster for TMEM30B:

    Transmembrane protein 30B
    Hs.146180  [show with all ESTs]
    Unigene Representative Sequence: NM_001017970
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000555868(uc001xfl.3) ENST00000557163 ENST00000554497 ENST00000355702


    miRNA
    Products:             		 OriGene 3'-UTR Clone: TMEM30B
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TMEM30B
    8/18 QIAGEN miScript miRNA Assays for microRNAs that regulate TMEM30B (see all 18):
    hsa-miR-579 hsa-miR-607 hsa-miR-1205 hsa-miR-3692 hsa-miR-298 hsa-miR-3658 hsa-miR-7-1* hsa-miR-186
    SwitchGear 3'UTR luciferase reporter plasmid: TMEM30B 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TMEM30B (see all 7)
    OriGene shRNA RFP: TMEM30B
    OriGene siRNA: TMEM30B
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TMEM30B
    Clone
    Products:             		 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TMEM30B (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TMEM30B
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: TMEM30B (NM_001017970)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM30B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM30B 
    Primer
    Products:            		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TMEM30B
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TMEM30B
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMEM30B
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMEM30B

    Additional cDNA sequence: 

    AK309281.1 AL080078.1 BC033845.1 BC101726.1 BC113559.1 

    4 DOTS entries:

    DT.441292  DT.429626  DT.95268786  DT.95082156 

    24/112 AceView cDNA sequences (see all 112):

    AI697010 AW001762 AI343269 AI261370 AA344230 AI568945 CA950865 AI420342 
    BF590065 BF222257 AI814620 AW271437 AI701446 AA975312 BM818997 BF476194 
    BF056190 BE669436 AI216049 AL080078 BF195471 AA337255 BE504706 AW264340 

    GeneLoc Exon Structure


    Expression
    for TMEM30B gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TMEM30B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: --

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    TMEM30B expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    4 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    LimbForelimb MyotomeLimb Muscle Progenitor CellsSkeletal Muscle
    Skeletal MuscleHyoid Arch MusclesMuscle Progenitor CellsSkeletal Muscle
    Skeletal MuscleMandibular Arch MusclesMuscle Progenitor CellsSkeletal Muscle
    KidneyRenal Collecting Duct SystemKidney
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    PureStem™ mesenchymal progenitor 7SMOO32 (Embryonic Progenitor Cell)Adipose, Bone, Cartilage

    See TMEM30B Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TMEM30B

    SOURCE GeneReport for Unigene cluster: Hs.146180
        SABiosciences Custom PCR Arrays for TMEM30B
    Primer
    Products:    		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TMEM30B
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TMEM30B
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMEM30B
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMEM30B
    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM30B

    Orthologs
    for TMEM30B gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for TMEM30B gene from 8/28 species (see all 28)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Tmem30b1 , 5 transmembrane protein 30B1, 5 90.98(n)1
    90.31(a)1    		   12 (30.65 cM)5
    2382571  NM_178715.31  NP_848830.11 
     735431145 
    lizard
    (Anolis carolinensis)    		 Reptilia TMEM30B6
    		 --
    		 54(a)
    		 1 ↔ 1
    		 LGc(6883422-6884756)
    zebrafish
    (Danio rerio)    		 Actinopterygii zgc:919081 zgc:91908 56.33(n)
    57.83(a)    		   431726  NM_001002179.1  NP_001002179.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG99476
    		 --
    		 45(a)
    		 1 → many
    		 X(16333180-16335313)
    worm
    (Caenorhabditis elegans)    		 Secernentea chat-16
    F20C5.46
    		 Protein F20C5.4
    		 41(a)
    34(a)
    		 possible ortholog
    possible ortholog
    		 IV(4447322-4449889)
    IV(8764867-8767437)
    baker's yeast
    (Saccharomyces cerevisiae)    		 Saccharomycetes CDC50(YCR094W)4
    CDC501    		 Endosomal protein that interacts with phospholipid more4
    Cdc50p1    		 43.82(n)1
    40.88(a)1    		   3(286762-287937)4
    8504561, 4  NP_010018.11, 4 
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons ALIS51 ALA-interacting subunit 5 45.87(n)
    40.59(a)    		   844283  NM_106593.3  NP_565210.1 
    rice
    (Oryza sativa)    		 Liliopsida Os02g01738001 hypothetical protein 45.46(n)
    38.36(a)    		   4328458  NM_001052578.1  NP_001046043.1 


    ENSEMBL Gene Tree for TMEM30B (if available)
    TreeFam Gene Tree for TMEM30B (if available) 

    Paralogs
    for TMEM30B gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TMEM30B gene
    TMEM30A2  
    1 SIMAP similar gene for TMEM30B using alignment to 1 protein entry:     CC50B_HUMAN:
    TMEM30A

    TMEM30B for paralogs           About GeneDecksing



    Genomic Variants
    for TMEM30B gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/124 NCBI SNPs in TMEM30B are shown (see all 124)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 14 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1813318821,2
    		--61743591(+) TATTAC/GTCTGT 1 -- ds50010--------
    rs1855532071,2
    		--61743593(+) TTAGTC/TTGTCT 1 -- ds50010--------
    rs1501676871,2
    		--61743659(+) CACTTC/TGGGAG 1 -- ds50010--------
    rs1386290911,2
    		--61743728(+) GAAACC/GCCATC 1 -- ds50010--------
    rs1427059211,2
    		--61743764(+) CTGGGC/TGTGGT 1 -- ds50010--------
    rs1915984741,2
    		--61743790(+) TCTCAG/TCTACT 1 -- ds50010--------
    rs1818809131,2
    		--61743843(+) AGGTTA/GCAGTG 1 -- ds50010--------
    rs23518051,2
    		C,A,--61743853(+) gagccG/Aaggtt 1 -- ds50011Minor allele frequency- A:0.50WA 2
    rs1873933151,2
    		--61743890(+) ACTCCA/GGCCTG 1 -- ds50010--------
    rs1116051891,2
    		--61744030(+) TTAACG/CATCTG 1 -- ds50011Minor allele frequency- C:0.50CSA 2

    HapMap Linkage Disequilibrium report for TMEM30B (61744088 - 61748558 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for TMEM30B: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TMEM30B
    DNA2.0 Custom Variant and Variant Library Synthesis for TMEM30B

    Disorders / Diseases
    for TMEM30B gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    TMEM30B for disorders           About GeneDecksing

    OMIM gene information: 611029    OMIM disorders: --

    4 diseases for TMEM30B:    About MalaCards
    intrahepatic cholestasis    cholestasis    meningioma    malaria


    Export disorders for TMEM30B gene to outside databases

    Publications
    for TMEM30B gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TMEM30B gene integrated from 9 sources:
    (articles sorted by number of sources associating them with TMEM30B)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification and characterization of CDC50A, CDC50B and CDC50C genes in silico. (PubMed id 15375526)1, 2, 3, 9 Katoh Y. and Katoh M. (2004)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. Differential expression profiling analyses identifies downregulation of 1p, 6q, and 14q genes and overexpression of 6p histone clust er 1 genes as markers of recurrence in meningiomas. (PubMed id 20685720)1 PAcrez-MagA!n E....MelAcndez B. (2010)
    5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
    6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    External Searches for TMEM30B gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing TMEM30B gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 161291 HGNC: 27254 AceView: TMEM30B Ensembl:ENSG00000182107 euGenes: HUgn161291
    ECgene: TMEM30B H-InvDB: TMEM30B

    Other Databases showing TMEM30B gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing TMEM30B gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TMEM30B Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for TMEM30B gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for TMEM30B gene:
    Search GeneIP for patents involving TMEM30B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    Products
    for TMEM30B gene

    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
    In Situ Hybridization Assays from
    Advanced Cell Diagnostics
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Phosphatase Activity Assays/Reagents   Browse Recombinant/Natural Proteins  
     Browse OriGene Antibodies   OriGene shRNA RFP for TMEM30B  
     OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TMEM30B   OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TMEM30B  
     OriGene Protein Over-expression Lysate for TMEM30B   Browse OriGene Fluorogenic Cell Assay Kits  
     OriGene siRNA for TMEM30B   OriGene 3'-UTR Clone for TMEM30B  
     OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TMEM30B   OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TMEM30B  
     Browse OriGene GFP tagged cDNA clones in CMV expression vector   Browse OriGene MicroRNA Expression Plasmids  
     Browse OriGene basic RS shRNAs   Browse OriGene validated miRNA SYBR primer pairs  
     Browse OriGene full length recombinant human proteins expressed in human HEK293 cells   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for TMEM30B   OriGene Custom Protein Services for TMEM30B  
     OriGene Custom Immunoassay Development  

         		 
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TMEM30B
     QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TMEM30B
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TMEM30B
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TMEM30B
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMEM30B
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMEM30B
     GenScript Custom Purified and Recombinant Proteins Services for TMEM30B GenScript cDNA clones with any tag delivered in your preferred vector for TMEM30B
     GenScript Custom Assay Services for TMEM30B GenScript Custom Superior Antibodies Services for TMEM30B
     GenScript Custom overexpressing Cell Line Services for TMEM30B CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in TMEM30B promoter
     Search Chromatin IP Primers for TMEM30B
     RT2 qPCR Primer Assay in human, mouse, rat TMEM30B
     Search GNC Networks for TMEM30B
     SABiosciences Custom PCR Arrays for TMEM30B
     Search Tocris compounds for TMEM30B
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     TMEM30B antibodies
     TMEM30B lysates
     Search for Antibodies for TMEM30B at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for TMEM30B
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     TMEM30B Proteins, Antibodies, CLIAs, and ELISAs
     Search LifeMap BioReagents cell lines for TMEM30B
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM30B
     SwitchGear 3'UTR luciferase reporter plasmids for TMEM30B
     Browse SwitchGear Promoter luciferase reporter plasmids for TMEM30B
     ThermoFisher Antibody for TMEM30B
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM30B
           
    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

    View Random Gene

    Category
    VWF
    (GIFTS: 73)
    von Willebrand factor
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 

    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Copyright © 1996-2013 , Weizmann Institute of Science. All Rights Reserved.
    Hot genes      Disease genes      TMEM30B gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 100 solr: 1.4