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Aliases for TMEM263 Gene

Aliases for TMEM263 Gene

  • Transmembrane Protein 263 2 3
  • C12orf23 3 4
  • UPF0444 Transmembrane Protein C12orf23 3
  • Chromosome 12 Open Reading Frame 23 2

External Ids for TMEM263 Gene

Previous HGNC Symbols for TMEM263 Gene

  • C12orf23

Previous GeneCards Identifiers for TMEM263 Gene

  • GC12P107350

Summaries for TMEM263 Gene

GeneCards Summary for TMEM263 Gene

TMEM263 (Transmembrane Protein 263) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM263 Gene

Genomics for TMEM263 Gene

Genomic Location for TMEM263 Gene

Start:
106,955,180 bp from pter
End:
106,978,778 bp from pter
Size:
23,599 bases
Orientation:
Plus strand

Genomic View for TMEM263 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMEM263 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM263 Gene

No data available for Regulatory Elements for TMEM263 Gene

Proteins for TMEM263 Gene

  • Protein details for TMEM263 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8WUH6-TM263_HUMAN
    Recommended name:
    Transmembrane protein 263
    Protein Accession:
    Q8WUH6
    Secondary Accessions:
    • B3KMN9

    Protein attributes for TMEM263 Gene

    Size:
    116 amino acids
    Molecular mass:
    11748 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMEM263 Gene

Proteomics data for TMEM263 Gene at MOPED

Post-translational modifications for TMEM263 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TMEM263 Gene

No data available for DME Specific Peptides for TMEM263 Gene

Domains for TMEM263 Gene

Protein Domains for TMEM263 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

Q8WUH6

UniProtKB/Swiss-Prot:

TM263_HUMAN :
  • Q8WUH6
Family:
  • Belongs to the TMEM263 family.
genes like me logo Genes that share domains with TMEM263: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for TMEM263 Gene

Function for TMEM263 Gene

Phenotypes for TMEM263 Gene

GenomeRNAi human phenotypes for TMEM263:
genes like me logo Genes that share phenotypes with TMEM263: view

Animal Model Products

CRISPR Products

miRNA for TMEM263 Gene

miRTarBase miRNAs that target TMEM263

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TMEM263

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targeting and HOMER Transcription for TMEM263 Gene

Localization for TMEM263 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM263 Gene

Membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for TMEM263 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM263: view

No data available for Subcellular locations from COMPARTMENTS for TMEM263 Gene

Pathways for TMEM263 Gene

SuperPathways for TMEM263 Gene

No Data Available

Interacting Proteins for TMEM263 Gene

Gene Ontology (GO) - Biological Process for TMEM263 Gene

None

No data available for Pathways by source for TMEM263 Gene

Transcripts for TMEM263 Gene

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TMEM263

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM263 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b · 6c · 6d · 6e · 6f
SP1: - - -
SP2: - -
SP3: - - -
SP4: - - - -
SP5: - - - - -
SP6: - - -

Relevant External Links for TMEM263 Gene

GeneLoc Exon Structure for
TMEM263
ECgene alternative splicing isoforms for
TMEM263

Expression for TMEM263 Gene

mRNA expression in normal human tissues for TMEM263 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for TMEM263 Gene

genes like me logo Genes that share expressions with TMEM263: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for TMEM263 Gene

Orthologs for TMEM263 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TMEM263 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C12H12orf23 35
  • 100 (n)
  • 100 (a)
C12orf23 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C5H12orf23 35
  • 96.55 (n)
  • 99.14 (a)
C5H12orf23 36
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C10H12orf23 35
  • 96.81 (n)
  • 97.39 (a)
C12orf23 36
  • 97 (a)
OneToOne
mouse
(Mus musculus)
Mammalia AI597468 35
  • 94.78 (n)
  • 97.39 (a)
AI597468 16
AI597468 36
  • 97 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia C12orf23 36
  • 95 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C12orf23 36
  • 95 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1563325 35
  • 95.36 (n)
  • 97.39 (a)
chicken
(Gallus gallus)
Aves C1H12ORF23 35
  • 84.48 (n)
  • 89.66 (a)
C1H12ORF23 36
  • 91 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C12orf23 36
  • 77 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia MGC75626 35
MGC75626 35
  • 73.68 (n)
  • 77.19 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.5400 35
zebrafish
(Danio rerio)
Actinopterygii C18H12orf23 36
  • 72 (a)
OneToOne
zgc:64098 35
  • 73.28 (n)
  • 75 (a)
Species with no ortholog for TMEM263:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TMEM263 Gene

ENSEMBL:
Gene Tree for TMEM263 (if available)
TreeFam:
Gene Tree for TMEM263 (if available)

Paralogs for TMEM263 Gene

No data available for Paralogs for TMEM263 Gene

Variants for TMEM263 Gene

Sequence variations from dbSNP and Humsavar for TMEM263 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type MAF
rs9720 -- 106,954,791(+) TCAAA(A/G)AAAAG upstream-variant-2KB
rs1053050 -- 106,973,446(+) CTTTG(C/T)TTGTC utr-variant-3-prime
rs1053051 -- 106,973,447(+) TTTGT(C/T)TGTCT utr-variant-3-prime
rs1053198 -- 106,973,970(+) AAAGC(A/C)CTATG utr-variant-3-prime
rs1055332 -- 106,954,847(-) ACGGG(A/T)GGAGA upstream-variant-2KB

Relevant External Links for TMEM263 Gene

HapMap Linkage Disequilibrium report
TMEM263

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for TMEM263 Gene

Disorders for TMEM263 Gene

No disorders were found for TMEM263 Gene.

No data available for UniProtKB/Swiss-Prot for TMEM263 Gene

Publications for TMEM263 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3
  5. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3

Products for TMEM263 Gene

Sources for TMEM263 Gene

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