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Aliases for TMEM261 Gene

Aliases for TMEM261 Gene

  • Transmembrane Protein 261 2 3
  • C9orf123 3 4
  • Chromosome 9 Open Reading Frame 123 2
  • Transmembrane Protein C9orf123 3

External Ids for TMEM261 Gene

Previous Symbols for TMEM261 Gene

  • C9orf123

Summaries for TMEM261 Gene

GeneCards Summary for TMEM261 Gene

TMEM261 (Transmembrane Protein 261) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM261 Gene

Genomics for TMEM261 Gene

Genomic Location for TMEM261 Gene

Start:
7,796,490 bp from pter
End:
7,888,380 bp from pter
Size:
91,891 bases
Orientation:
Minus strand

Genomic View for TMEM261 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMEM261 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM261 Gene

No data available for Regulatory Elements for TMEM261 Gene

Proteins for TMEM261 Gene

  • Protein details for TMEM261 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96GE9-TM261_HUMAN
    Recommended name:
    Transmembrane protein 261
    Protein Accession:
    Q96GE9
    Secondary Accessions:
    • A8K9B7
    • Q5T6Y9
    • Q9NT74

    Protein attributes for TMEM261 Gene

    Size:
    116 amino acids
    Molecular mass:
    12257 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for TMEM261 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TMEM261 Gene

Proteomics data for TMEM261 Gene at MOPED

Post-translational modifications for TMEM261 Gene

No Post-translational modifications

Other Protein References for TMEM261 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TMEM261 Gene

Domains for TMEM261 Gene

Protein Domains for TMEM261 Gene

InterPro:
ProtoNet:
genes like me logo Genes that share domains with TMEM261: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TMEM261 Gene

Function for TMEM261 Gene

Phenotypes for TMEM261 Gene

GenomeRNAi human phenotypes for TMEM261:
genes like me logo Genes that share phenotypes with TMEM261: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TMEM261 Gene

Localization for TMEM261 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM261 Gene

Membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for TMEM261 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM261: view

Pathways for TMEM261 Gene

SuperPathways for TMEM261 Gene

No Data Available

Interacting Proteins for TMEM261 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000350961%0d%0a9606.ENSP00000313199%0d%0a
Selected Interacting proteins: ENSP00000350961 Q96GE9-TM261_HUMAN for TMEM261 Gene via STRING I2D

Gene Ontology (GO) - Biological Process for TMEM261 Gene

None

No data available for Pathways by source for TMEM261 Gene

Transcripts for TMEM261 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM261 Gene

ExUns: 1a · 1b · 1c · 1d · 1e · 1f · 1g ^ 2a · 2b · 2c · 2d
SP1: -
SP2: - - -
SP3: - -
SP4:
SP5: - - - -

Relevant External Links for TMEM261 Gene

GeneLoc Exon Structure for
TMEM261
ECgene alternative splicing isoforms for
TMEM261

Expression for TMEM261 Gene

mRNA expression in normal human tissues for TMEM261 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for TMEM261 Gene

genes like me logo Genes that share expressions with TMEM261: view

Orthologs for TMEM261 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TMEM261 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC100611439 36
  • 90.99 (n)
  • 82.88 (a)
cow
(Bos Taurus)
Mammalia C8H9orf123 36
  • 74.36 (n)
  • 64.84 (a)
MGC127919 37
  • 57 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C11H9orf123 36
  • 73.87 (n)
  • 65.77 (a)
TMEM261 37
  • 66 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 3110001D03Rik 16
Tmem261 36
  • 71.49 (n)
  • 65.79 (a)
Tmem261 37
  • 55 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia TMEM261 37
  • 56 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Tmem261 36
  • 71.05 (n)
  • 60.53 (a)
zebrafish
(Danio rerio)
Actinopterygii TMEM261 37
  • 36 (a)
OneToOne
Species with no ortholog for TMEM261:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TMEM261 Gene

ENSEMBL:
Gene Tree for TMEM261 (if available)
TreeFam:
Gene Tree for TMEM261 (if available)

Paralogs for TMEM261 Gene

Pseudogenes.org Pseudogenes for TMEM261 Gene

genes like me logo Genes that share paralogs with TMEM261: view

No data available for Paralogs for TMEM261 Gene

Variants for TMEM261 Gene

Sequence variations from dbSNP and Humsavar for TMEM261 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
rs14059 -- 7,799,606(-) CGCCT(G/T)TTGAA reference, synonymous-codon
rs1127430 - 7,799,653(-) CTGCG(A/C)CCCCA missense, reference
rs1132047 -- 7,796,848(-) TAACA(C/T)ATTTT utr-variant-3-prime
rs2297554 -- 7,799,787(+) GTAAA(C/T)GACGC utr-variant-5-prime
rs2990600 -- 7,796,329(+) AGCAC(G/T)GGCAG downstream-variant-500B

Relevant External Links for TMEM261 Gene

HapMap Linkage Disequilibrium report
TMEM261

No data available for Structural Variations from Database of Genomic Variants (DGV) for TMEM261 Gene

Disorders for TMEM261 Gene

No disorders were found for TMEM261 Gene.

No data available for UniProtKB/Swiss-Prot for TMEM261 Gene

Publications for TMEM261 Gene

  1. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Identification and functional analysis of 9p24 amplified genes in human breast cancer. (PMID: 21666724) Wu J. … Yang Z.Q. (Oncogene 2012) 2 3
  4. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4

Products for TMEM261 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate TMEM261
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for TMEM261
    • Block miRNA regulation of TMEM261 using miScript Target Protectors

    Sources for TMEM261 Gene

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