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Aliases for TMEM260 Gene

Aliases for TMEM260 Gene

  • Transmembrane Protein 260 2 3
  • C14orf101 3 4
  • Chromosome 14 Open Reading Frame 101 2
  • UPF0679 Protein C14orf101 3

External Ids for TMEM260 Gene

Previous HGNC Symbols for TMEM260 Gene

  • C14orf101

Previous GeneCards Identifiers for TMEM260 Gene

  • GC14P056956

Summaries for TMEM260 Gene

GeneCards Summary for TMEM260 Gene

TMEM260 (Transmembrane Protein 260) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM260 Gene

Genomics for TMEM260 Gene

Genomic Location for TMEM260 Gene

56,488,354 bp from pter
56,650,606 bp from pter
162,253 bases
Plus strand

Genomic View for TMEM260 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMEM260 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM260 Gene

No data available for Regulatory Elements for TMEM260 Gene

Proteins for TMEM260 Gene

  • Protein details for TMEM260 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Transmembrane protein 260
    Protein Accession:
    Secondary Accessions:
    • A8KAN4
    • B3KPF5
    • Q86XE1

    Protein attributes for TMEM260 Gene

    707 amino acids
    Molecular mass:
    79536 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAA91139.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BC045556; Type=Frameshift; Positions=212; Evidence={ECO:0000305};

    Alternative splice isoforms for TMEM260 Gene


neXtProt entry for TMEM260 Gene

Proteomics data for TMEM260 Gene at MOPED

Post-translational modifications for TMEM260 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for TMEM260 Gene

Domains for TMEM260 Gene

Protein Domains for TMEM260 Gene


Graphical View of Domain Structure for InterPro Entry



  • Q9NX78
  • Belongs to the TMEM260 family.
genes like me logo Genes that share domains with TMEM260: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for TMEM260 Gene

Function for TMEM260 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TMEM260 Gene

Localization for TMEM260 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM260 Gene

Membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for TMEM260 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM260: view

No data available for Subcellular locations from COMPARTMENTS for TMEM260 Gene

Pathways for TMEM260 Gene

SuperPathways for TMEM260 Gene

No Data Available

Interacting Proteins for TMEM260 Gene

Gene Ontology (GO) - Biological Process for TMEM260 Gene


No data available for Pathways by source for TMEM260 Gene

Transcripts for TMEM260 Gene

Unigene Clusters for TMEM260 Gene

Transmembrane protein 260:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TMEM260

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for TMEM260
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM260 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13 ^ 14a · 14b · 14c
SP1: - -
SP2: - - -
SP3: - - -
SP4: - -
SP5: -

Relevant External Links for TMEM260 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TMEM260 Gene

mRNA expression in normal human tissues for TMEM260 Gene

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for TMEM260 Gene

SOURCE GeneReport for Unigene cluster for TMEM260 Gene Hs.497253

genes like me logo Genes that share expressions with TMEM260: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for TMEM260 Gene

Orthologs for TMEM260 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TMEM260 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C14H14ORF101 36
  • 99 (a)
TMEM260 35
  • 99.29 (n)
  • 99.29 (a)
(Bos Taurus)
Mammalia TMEM260 35
  • 90.49 (n)
  • 90.35 (a)
TMEM260 36
  • 84 (a)
(Canis familiaris)
Mammalia TMEM260 35
  • 91.04 (n)
  • 90.52 (a)
TMEM260 36
  • 91 (a)
(Mus musculus)
Mammalia 6720456H20Rik 16
Tmem260 35
  • 83.74 (n)
  • 82.93 (a)
Tmem260 36
  • 83 (a)
(Monodelphis domestica)
Mammalia TMEM260 36
  • 80 (a)
(Ornithorhynchus anatinus)
Mammalia TMEM260 36
  • 75 (a)
(Rattus norvegicus)
Mammalia Tmem260 35
  • 82.88 (n)
  • 83.64 (a)
(Gallus gallus)
Aves C5H14ORF101 35
  • 72.21 (n)
  • 72.31 (a)
TMEM260 36
  • 69 (a)
(Anolis carolinensis)
Reptilia TMEM260 36
  • 67 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia tmem260 35
  • 67.62 (n)
  • 64.5 (a)
(Danio rerio)
Actinopterygii LOC559650 35
  • 56.66 (n)
  • 50.46 (a)
tmem260 36
  • 49 (a)
Species with no ortholog for TMEM260:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TMEM260 Gene

Gene Tree for TMEM260 (if available)
Gene Tree for TMEM260 (if available)

Paralogs for TMEM260 Gene

Selected SIMAP similar genes for TMEM260 Gene using alignment to 9 proteins:

genes like me logo Genes that share paralogs with TMEM260: view

No data available for Paralogs for TMEM260 Gene

Variants for TMEM260 Gene

Sequence variations from dbSNP and Humsavar for TMEM260 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type MAF
rs913742 -- 56,634,964(-) AAATG(C/T)AGAAT intron-variant
rs913744 -- 56,634,535(-) GGATA(A/C/G)GTCAT intron-variant
rs990637 -- 56,645,777(-) GTAAA(G/T)GCTGT intron-variant
rs1041315 -- 56,622,879(-) TATAA(A/C)TGCAA intron-variant
rs1041316 - 56,633,141(-) AGATA(C/T)TTTTT missense, reference, nc-transcript-variant

Relevant External Links for TMEM260 Gene

HapMap Linkage Disequilibrium report
Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for TMEM260 Gene

Disorders for TMEM260 Gene

No disorders were found for TMEM260 Gene.

No data available for UniProtKB/Swiss-Prot for TMEM260 Gene

Publications for TMEM260 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. A polymorphism at the microRNA binding site in the 3' untranslated region of C14orf101 is associated with non-Hodgkin lymphoma overall survival. (PMID: 24831772) Yang B. … Guo Z. (Cancer Genet 2014) 3
  4. The DNA sequence and analysis of human chromosome 14. (PMID: 12508121) Heilig R. … Weissenbach J. (Nature 2003) 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for TMEM260 Gene

Sources for TMEM260 Gene

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