Aliases for TMEM258 Gene
External Ids for TMEM258 Gene
Previous HGNC Symbols for TMEM258 Gene
Previous GeneCards Identifiers for TMEM258 Gene
GeneCards Summary for TMEM258 Gene
TMEM258 (Transmembrane Protein 258) is a Protein Coding gene.
UniProtKB/Swiss-Prot for TMEM258 Gene
Acts as component of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. Required for full OST catalytic activity in N-glycosylation (PubMed:26472760, PubMed:27974209). Involved in endoplasmic reticulum (ER) homeostasis in the colonic epithelium (By similarity).