Free for academic non-profit institutions. Other users need a Commercial license

Aliases for TMEM255B Gene

Aliases for TMEM255B Gene

  • Transmembrane Protein 255B 2 3 5
  • Family With Sequence Similarity 70, Member B 2 3
  • Protein FAM70B 3 4
  • FAM70B 3 4

External Ids for TMEM255B Gene

Previous HGNC Symbols for TMEM255B Gene

  • FAM70B

Previous GeneCards Identifiers for TMEM255B Gene

  • GC13P114463

Summaries for TMEM255B Gene

GeneCards Summary for TMEM255B Gene

TMEM255B (Transmembrane Protein 255B) is a Protein Coding gene. An important paralog of this gene is TMEM255A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM255B Gene

Genomics for TMEM255B Gene

Regulatory Elements for TMEM255B Gene

Enhancers for TMEM255B Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around TMEM255B on UCSC Golden Path with GeneCards custom track

Promoters for TMEM255B Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around TMEM255B on UCSC Golden Path with GeneCards custom track

Genomic Location for TMEM255B Gene

Chromosome:
13
Start:
113,759,210 bp from pter
End:
113,816,995 bp from pter
Size:
57,786 bases
Orientation:
Plus strand

Genomic View for TMEM255B Gene

Genes around TMEM255B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TMEM255B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TMEM255B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM255B Gene

Proteins for TMEM255B Gene

  • Protein details for TMEM255B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8WV15-T255B_HUMAN
    Recommended name:
    Transmembrane protein 255B
    Protein Accession:
    Q8WV15

    Protein attributes for TMEM255B Gene

    Size:
    326 amino acids
    Molecular mass:
    34609 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMEM255B Gene

Proteomics data for TMEM255B Gene at MOPED

Post-translational modifications for TMEM255B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TMEM255B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TMEM255B Gene

Domains & Families for TMEM255B Gene

Protein Domains for TMEM255B Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TMEM255B Gene

Graphical View of Domain Structure for InterPro Entry

Q8WV15

UniProtKB/Swiss-Prot:

T255B_HUMAN :
  • Belongs to the TMEM255 family.
Family:
  • Belongs to the TMEM255 family.
genes like me logo Genes that share domains with TMEM255B: view

No data available for Gene Families for TMEM255B Gene

Function for TMEM255B Gene

Phenotypes for TMEM255B Gene

MGI mutant phenotypes for TMEM255B:
inferred from 1 alleles
GenomeRNAi human phenotypes for TMEM255B:
genes like me logo Genes that share phenotypes with TMEM255B: view

Animal Models for TMEM255B Gene

MGI Knock Outs for TMEM255B:

Animal Model Products

CRISPR Products

miRNA for TMEM255B Gene

miRTarBase miRNAs that target TMEM255B

Inhibitory RNA Products

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for TMEM255B Gene

Localization for TMEM255B Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM255B Gene

Membrane; Multi-pass membrane protein.

No data available for Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for TMEM255B Gene

Pathways & Interactions for TMEM255B Gene

SuperPathways for TMEM255B Gene

No Data Available

Interacting Proteins for TMEM255B Gene

Gene Ontology (GO) - Biological Process for TMEM255B Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TMEM255B Gene

Drugs & Compounds for TMEM255B Gene

No Compound Related Data Available

Transcripts for TMEM255B Gene

Unigene Clusters for TMEM255B Gene

Transmembrane protein 255B:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM255B Gene

No ASD Table

Relevant External Links for TMEM255B Gene

GeneLoc Exon Structure for
TMEM255B
ECgene alternative splicing isoforms for
TMEM255B

Expression for TMEM255B Gene

mRNA expression in normal human tissues for TMEM255B Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for TMEM255B Gene



SOURCE GeneReport for Unigene cluster for TMEM255B Gene Hs.280805

genes like me logo Genes that share expression patterns with TMEM255B: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for TMEM255B Gene

Orthologs for TMEM255B Gene

This gene was present in the common ancestor of chordates.

Orthologs for TMEM255B Gene

Organism Taxonomy Gene Similarity Type Details
mouse
(Mus musculus)
Mammalia Tmem255b 35
  • 77.85 (n)
  • 78.46 (a)
Tmem255b 16
Tmem255b 36
  • 78 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia FAM70B 35
  • 98.92 (n)
  • 99.46 (a)
cow
(Bos Taurus)
Mammalia TMEM255B 36
  • 65 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TMEM255B 36
  • 59 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia TMEM255B 36
  • 65 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia TMEM255B 36
  • 71 (a)
OneToOne
chicken
(Gallus gallus)
Aves FAM70B 35
  • 67.82 (n)
  • 70 (a)
TMEM255B 36
  • 65 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia TMEM255B 36
  • 63 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia tmem255b 35
  • 63.81 (n)
  • 64.44 (a)
zebrafish
(Danio rerio)
Actinopterygii TMEM255B 36
  • 38 (a)
OneToOne
Species with no ortholog for TMEM255B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TMEM255B Gene

ENSEMBL:
Gene Tree for TMEM255B (if available)
TreeFam:
Gene Tree for TMEM255B (if available)

Paralogs for TMEM255B Gene

Paralogs for TMEM255B Gene

(1) SIMAP similar genes for TMEM255B Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with TMEM255B: view

Variants for TMEM255B Gene

Sequence variations from dbSNP and Humsavar for TMEM255B Gene

SNP ID Clin Chr 13 pos Sequence Context AA Info Type
rs3934938 -- 113,801,016(+) ACCCC(C/T)ATATC intron-variant
rs3934939 -- 113,801,017(+) CCCCT(A/G)TATCT intron-variant
rs3934940 -- 113,801,030(+) ACCTG(A/C)GGGAG intron-variant
rs3934941 -- 113,801,051(+) CTGGG(A/G)ACCCC intron-variant
rs3935485 -- 113,787,644(-) GCTCA(C/T)TAACA intron-variant

Variation tolerance for TMEM255B Gene

Residual Variation Intolerance Score: 92.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.63; 56.61% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TMEM255B Gene

HapMap Linkage Disequilibrium report
TMEM255B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for TMEM255B Gene

Disorders for TMEM255B Gene

Relevant External Links for TMEM255B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TMEM255B

No disorders were found for TMEM255B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TMEM255B Gene

Publications for TMEM255B Gene

  1. The DNA sequence and analysis of human chromosome 13. (PMID: 15057823) Dunham A. … Ross M.T. (Nature 2004) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  4. Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. (PMID: 23382691) Lauc G. … Rudan I. (PLoS Genet. 2013) 3
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3

Products for TMEM255B Gene

Sources for TMEM255B Gene

Content