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Aliases for TMEM255A Gene

Aliases for TMEM255A Gene

  • Transmembrane Protein 255A 2 3
  • Family With Sequence Similarity 70, Member A 2 3
  • Protein FAM70A 3 4
  • FAM70A 3 4

External Ids for TMEM255A Gene

Previous HGNC Symbols for TMEM255A Gene

  • FAM70A

Previous GeneCards Identifiers for TMEM255A Gene

  • GC0XM119393

Summaries for TMEM255A Gene

GeneCards Summary for TMEM255A Gene

TMEM255A (Transmembrane Protein 255A) is a Protein Coding gene. An important paralog of this gene is TMEM255B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM255A Gene

Genomics for TMEM255A Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for TMEM255A Gene

Start:
120,258,650 bp from pter
End:
120,311,556 bp from pter
Size:
52,907 bases
Orientation:
Minus strand

Genomic View for TMEM255A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMEM255A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM255A Gene

No data available for Regulatory Elements for TMEM255A Gene

Proteins for TMEM255A Gene

  • Protein details for TMEM255A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5JRV8-T255A_HUMAN
    Recommended name:
    Transmembrane protein 255A
    Protein Accession:
    Q5JRV8
    Secondary Accessions:
    • A8K0W9
    • B1APR4
    • B3KPI6
    • E9PAR3
    • Q86Y72
    • Q9NWN8

    Protein attributes for TMEM255A Gene

    Size:
    349 amino acids
    Molecular mass:
    38449 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for TMEM255A Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TMEM255A Gene

Proteomics data for TMEM255A Gene at MOPED

Post-translational modifications for TMEM255A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TMEM255A Gene

No data available for DME Specific Peptides for TMEM255A Gene

Domains for TMEM255A Gene

Protein Domains for TMEM255A Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

Q5JRV8

UniProtKB/Swiss-Prot:

T255A_HUMAN :
  • Q5JRV8
Family:
  • Belongs to the TMEM255 family.
genes like me logo Genes that share domains with TMEM255A: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for TMEM255A Gene

Function for TMEM255A Gene

Animal Model Products

CRISPR Products

miRNA for TMEM255A Gene

miRTarBase miRNAs that target TMEM255A

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TMEM255A

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for TMEM255A Gene

Localization for TMEM255A Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM255A Gene

Membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for TMEM255A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM255A: view

No data available for Subcellular locations from COMPARTMENTS for TMEM255A Gene

Pathways for TMEM255A Gene

SuperPathways for TMEM255A Gene

No Data Available

Interacting Proteins for TMEM255A Gene

Selected Interacting proteins: Q5JRV8-T255A_HUMAN for TMEM255A Gene via I2D

Symbol External ID(s) Details
RAC1

Gene Ontology (GO) - Biological Process for TMEM255A Gene

None

No data available for Pathways by source for TMEM255A Gene

Transcripts for TMEM255A Gene

Unigene Clusters for TMEM255A Gene

Transmembrane protein 255A:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TMEM255A

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM255A Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b
SP1: -
SP2: - -
SP3: -
SP4: - - - -

Relevant External Links for TMEM255A Gene

GeneLoc Exon Structure for
TMEM255A
ECgene alternative splicing isoforms for
TMEM255A

Expression for TMEM255A Gene

mRNA expression in normal human tissues for TMEM255A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for TMEM255A Gene

This gene is overexpressed in Brain - Hypothalamus (8.6) and Brain - Substantia nigra (6.0).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for TMEM255A Gene

SOURCE GeneReport for Unigene cluster for TMEM255A Gene Hs.437563

genes like me logo Genes that share expressions with TMEM255A: view

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for TMEM255A Gene

Orthologs for TMEM255A Gene

This gene was present in the common ancestor of chordates.

Orthologs for TMEM255A Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia FAM70A 35
  • 94.46 (n)
  • 97.99 (a)
MGC142908 36
  • 98 (a)
OneToOne
dog
(Canis familiaris)
Mammalia FAM70A 35
  • 93.79 (n)
  • 98.28 (a)
TMEM255A 36
  • 98 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tmem255a 35
  • 91.21 (n)
  • 95.42 (a)
Tmem255a 16
Tmem255a 36
  • 95 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia TMEM255A 36
  • 77 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia TMEM255A 36
  • 88 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Tmem255a 35
  • 91.31 (n)
  • 95.42 (a)
chicken
(Gallus gallus)
Aves TMEM255A 36
  • 85 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia TMEM255A 36
  • 80 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia tmem255a 35
  • 68.79 (n)
  • 71.91 (a)
zebrafish
(Danio rerio)
Actinopterygii tmem255a 35
  • 64.46 (n)
  • 66.88 (a)
TMEM255A 36
  • 62 (a)
OneToOne
Species with no ortholog for TMEM255A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TMEM255A Gene

ENSEMBL:
Gene Tree for TMEM255A (if available)
TreeFam:
Gene Tree for TMEM255A (if available)

Paralogs for TMEM255A Gene

Paralogs for TMEM255A Gene

Selected SIMAP similar genes for TMEM255A Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with TMEM255A: view

Variants for TMEM255A Gene

Sequence variations from dbSNP and Humsavar for TMEM255A Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs3030544 -- 120,264,895(+) ttttt(-/TT)ataca intron-variant
rs3752341 -- 120,261,049(-) ACTAA(A/C)GTTTT intron-variant
rs3810749 -- 120,311,160(-) AAGCC(A/G)GAGAG intron-variant
rs3810750 -- 120,309,200(-) GCACT(A/G)GCAAA intron-variant
rs3810751 -- 120,286,778(-) AGTGG(A/G)AGCCC intron-variant

Relevant External Links for TMEM255A Gene

HapMap Linkage Disequilibrium report
TMEM255A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for TMEM255A Gene

Disorders for TMEM255A Gene

No disorders were found for TMEM255A Gene.

No data available for UniProtKB/Swiss-Prot for TMEM255A Gene

Publications for TMEM255A Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3

Products for TMEM255A Gene

  • antibodies-online peptides for TMEM255A
  • antibodies-online antibodies for TMEM255A
  • antibodies-online kits for TMEM255A

Sources for TMEM255A Gene

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