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TMEM254 Gene

protein-coding   GIFtS: 36
GCID: GC10P081838

Transmembrane Protein 254

(Previous name: chromosome 10 open reading frame 57)
(Previous symbol: C10orf57)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Transmembrane Protein 2541 2
C10orf571 2 3
Chromosome 10 Open Reading Frame 571
bA369J21.62
Transmembrane Protein C10orf572

External Ids:    HGNC: 258041   Entrez Gene: 801952   Ensembl: ENSG000001336787   UniProtKB: Q8TBM73   
ORGUL members:         

Export aliases for TMEM254 gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TMEM254 Gene:
TMEM254 (transmembrane protein 254) is a protein-coding gene.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000010.10  NT_030059.14  NC_018921.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for TMEM254
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for TMEM254

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TMEM254


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q22.3   Ensembl cytogenetic band:  10q22.3   HGNC cytogenetic band: 10q23.1

TMEM254 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMEM254 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10P081838:  view genomic region     (about GC identifiers)

Start:
81,838,402 bp from pter      End:
81,852,313 bp from pter
Size:
13,912 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: TM254_HUMAN, Q8TBM7 (See protein sequence)
Recommended Name: Transmembrane protein 254  
Size: 123 amino acids; 14243 Da
Secondary accessions: D3DWC8 Q53HP4 Q5JTC0 Q5JTC1 Q6IA45 Q9H8S6
Alternative splicing: 3 isoforms:  Q8TBM7-1   Q8TBM7-2   Q8TBM7-3   (Gene prediction based on EST data)

Explore the universe of human proteins at neXtProt for TMEM254: NX_Q8TBM7

REFSEQ proteins (9 alternative transcripts): 
NP_001257296.1  NP_001257297.1  NP_001257298.1  NP_001257299.1  NP_001257300.1  NP_001257301.1  NP_001257302.1  NP_001257303.1  
NP_079401.2  

ENSEMBL proteins: 
 ENSP00000361355   ENSP00000361349   ENSP00000361348   ENSP00000361347   ENSP00000393450  
 ENSP00000361351  

TMEM254 Human Recombinant Protein Products:

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Browse recombinant and purified proteins available from Enzo Life Sciences
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OriGene Protein Over-expression Lysate for TMEM254
OriGene Custom MassSpec
OriGene Custom Protein Services for TMEM254
GenScript Custom Purified and Recombinant Proteins Services for TMEM254
Novus Biologicals TMEM254 Lysate
Browse Sino Biological Recombinant Proteins
Browse Sino Biological Cell Lysates
Browse ProSpec Recombinant Proteins
Browse Proteins at Cloud-Clone Corp.

 
Search eBioscience for Proteins for TMEM254 

 
Search antibodies-online for proteins for TMEM254 

 
antibodies-online peptides for TMEM254

TMEM254 Antibody Products:

Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
Browse R&D Systems for Antibodies
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OriGene Custom Antibody Services for TMEM254
Novus Biologicals TMEM254 Antibody
Search for Antibodies for TMEM254 at Abcam
Browse Antibodies at Cloud-Clone Corp.
Search ThermoFisher Antibodies for TMEM254
LSBio Antibodies in human, mouse, rat for TMEM254
antibodies-online antibodies for TMEM254 (11 products) 

TMEM254 Assay Products:

Browse Kits and Assays available from EMD Millipore
OriGene Custom Assay Services for TMEM254
Browse R&D Systems for biochemical assays
GenScript Custom Assay Services for TMEM254
Browse Enzo Life Sciences for kits & assays
Browse ELISAs at Cloud-Clone Corp.
Browse CLIAs at Cloud-Clone Corp.
Search eBioscience for ELISAs for TMEM254 
antibodies-online kits for TMEM254 (2 products) 


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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1 InterPro protein domain:
 IPR028110 DUF4499

Graphical View of Domain Structure for InterPro Entry Q8TBM7

ProtoNet protein and cluster: Q8TBM7


Find genes that share domains with TMEM254           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Phenotypes:
     2 GenomeRNAi human phenotypes for TMEM254:
 Decreased influenza A/WSN/33 r  Increased 8N DNA content 

Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TMEM254
   inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TMEM254

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TMEM254
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TMEM254

miRNA
Products:
    
miRTarBase miRNAs that target TMEM254:
hsa-mir-331-3p (MIRT043526)

Block miRNA regulation of human, mouse, rat TMEM254 using miScript Target Protectors
Search for qRT-PCR Assays for microRNAs that regulate TMEM254
SwitchGear 3'UTR luciferase reporter plasmidTMEM254 3' UTR sequence
Inhib. RNA
Products:
    
OriGene RNAi products in human, mouse, rat for TMEM254
Predesigned siRNA for gene silencing in human, mouse, rat TMEM254

Gene Editing
Products:
DNA2.0 Custom Protein Engineering Service for TMEM254

Clone
Products:
     
OriGene clones in human, mouse for TMEM254 (see all 8)
OriGene ORF clones in mouse, rat for TMEM254
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript Custom all cDNA clones Services for TMEM254
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM254
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM254

Cell Line
Products:
     
GenScript Custom overexpressing Cell Line Services for TMEM254
Browse ESI BIO Cell Lines and PureStem Progenitors for TMEM254 
In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM254


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
TM254_HUMAN, Q8TBM7: Membrane; Multi-pass membrane protein (Potential)

Gene Ontology (GO): 1 cellular component term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0016021integral component of membrane IEA--

Find genes that share ontologies with TMEM254           About GenesLikeMe


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TMEM254
Interactions:

    Search GeneGlobe Interaction Network for TMEM254

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for TMEM254 (TM254)



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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REFSEQ mRNAs for TMEM254 gene (9 alternative transcripts): 
NM_001270367.1  NM_001270368.1  NM_001270369.1  NM_001270370.1  NM_001270371.1  NM_001270372.1  NM_001270373.1  NM_001270374.1  
NM_025125.3  

Unigene Cluster for TMEM254:

Transmembrane protein 254
Hs.169982  [show with all ESTs]
Unigene Representative Sequence: NM_001270374
12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000472622 ENST00000372281(uc001kbl.3 uc009xsn.3) ENST00000372275
ENST00000372274 ENST00000372273(uc010qlv.2 uc010qlw.2) ENST00000467529(uc001kbn.4 uc009xsp.3 uc001kbo.4)
ENST00000463029 ENST00000476173 ENST00000483732 ENST00000463209 ENST00000450179
ENST00000372277
miRNA
Products:
     
Block miRNA regulation of human, mouse, rat TMEM254 using miScript Target Protectors
Search for qRT-PCR Assays for microRNAs that regulate TMEM254
SwitchGear 3'UTR luciferase reporter plasmidTMEM254 3' UTR sequence
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for TMEM254
Predesigned siRNA for gene silencing in human, mouse, rat TMEM254
Clone
Products:
     
OriGene clones in human, mouse for TMEM254 (see all 8)
OriGene ORF clones in mouse, rat for TMEM254
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript Custom all cDNA clones Services for TMEM254
DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM254
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM254
Primer
Products:
    
OriGene qPCR primer pairs and template standards for TMEM254
OriGene qSTAR qPCR primer pairs in human, mouse for TMEM254
Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat TMEM254
  QuantiTect SYBR Green Assays in human, mouse, rat TMEM254
  QuantiFast Probe-based Assays in human, mouse, rat TMEM254

Additional mRNA sequence: 

AF147339.1 AK023325.1 AK222536.1 AK300490.1 AK309425.1 AK309980.1 AK310160.1 AK311563.1 
AL832397.1 AL832483.1 BC022252.1 BX537803.1 CR457310.1 DQ786319.1 NR_072984.1 NR_072985.1 
NR_072986.1 NR_072987.1 

13 DOTS entries:

DT.214964  DT.92432105  DT.95315410  DT.100036036  DT.100705708  DT.100799475  DT.92432103  DT.92432106 
DT.95274605  DT.100748205  DT.121256554  DT.444343  DT.92432101 

Selected AceView cDNA sequences (see all 222):

CR606165 BG742982 AW197647 BG697979 BU739270 AI206962 NM_025125 AA190897 
AI188925 BM724886 BC022252 Z41201 AI083554 N32425 BM672194 AW517839 
BF445609 AW014014 BM693871 AL832397 CR622847 AF147339 AA868251 BM717322 

GeneLoc Exon Structure

Selected Alternative Splicing Database (ASD) splice patterns (SP) for TMEM254 (see all 10)    About this scheme

ExUns: 1a · 1b ^ 2a · 2b · 2c ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8 ^ 9a · 9b · 9c · 9d · 9e
SP1:              -     -     -     -     -     -                       -     -                                       
SP2:                                -     -     -                       -     -                                       
SP3:              -     -     -     -     -     -                       -     -     -                                 
SP4:              -     -     -     -     -     -                             -     -                                 
SP5:                                -     -     -                       -     -     -                                 


ECgene alternative splicing isoforms for TMEM254

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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TMEM254 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: --
TMEM254 Expression
About this image


TMEM254 expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database
 selected tissues (see all 2) fully expand
 
 Testis (Reproductive System)
         XY Germ Cells Testis Cord
 
 Gonad
         XY Germ Cells Testis Cord
TMEM254 Protein expression data from MOPED1, PaxDb2 and MaxQB3 --

SOURCE GeneReport for Unigene cluster: Hs.169982
    Custom PCR Arrays for TMEM254
Primer
Products:
OriGene qPCR primer pairs and template standards for TMEM254
OriGene qSTAR qPCR primer pairs in human, mouse for TMEM254
Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat TMEM254
QuantiTect SYBR Green Assays in human, mouse, rat TMEM254
QuantiFast Probe-based Assays in human, mouse, rat TMEM254
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM254

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of chordates.

Orthologs for TMEM254 gene from Selected species (see all 11)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Tmem254a5 DNA segment, Chr 14, ERATO Doi 449, expressed   --   14 (15.19 cM) 25924000 
chicken
(Gallus gallus)
Aves C10ORF576
transmembrane protein C10orf57 homolog
41(a)
1 ↔ 1
6(4583363-4588681)
lizard
(Anolis carolinensis)
Reptilia --
--
(see all 4)
Uncharacterized protein
(see all 4)
45(a)
37(a)
(see all 4)
many → 1
many → 1
(see all 4)
GL343495.1(497743-506142)
GL343967.1(20962-28728)
tropical clawed frog
(Xenopus tropicalis)
Amphibia fam213a1 family with sequence similarity 213, member A 59.84(n)
53.28(a)
  496918  NM_001011433.1  NP_001011433.1 
zebrafish
(Danio rerio)
Actinopterygii zgc:640431 zgc:64043 59.29(n)
46.72(a)
  393341  NM_200370.1  NP_956664.1 


ENSEMBL Gene Tree for TMEM254 (if available)
TreeFam Gene Tree for TMEM254 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for TMEM254 gene

Find genes that share paralogs with TMEM254           About GenesLikeMe


5 Pseudogenes.org Pseudogenes for TMEM254
PGOHUM00000247721 PGOHUM00000248005 PGOHUM00000248901 PGOHUM00000246188 PGOHUM00000240289


(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for TMEM254 (see all 315)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 10 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs124143321,2
C,F,H--81840955(+) tgagcC/Tgtgat 13 -- int16Minor allele frequency- T:0.08NA WA EA 366
rs65848271,2
C,F,A,H--81840963(+) gatcaT/Ggccac 13 -- int111Minor allele frequency- G:0.35NA WA CSA EA 375
rs1848716421,2
--81840998(+) CGAGAA/TCCCTT 13 -- int10--------
rs1876257411,2
--81841013(+) ACAAAC/GAAAAC 13 -- int10--------
rs762732361,2
C--81841046(+) AAGAC-/TTTAAGA 13 -- int10--------
rs1925296941,2
--81841243(+) CATAGC/TGAGAC 13 -- int10--------
rs1117514601,2
C,F--81841298(+) ACACAC/TGTGTA 13 -- int12Minor allele frequency- T:0.04CSA WA 120
rs1458300521,2
--81841332(+) GGTGGA/GAGGAT 13 -- int10--------
rs1144360531,2
F--81841405(+) AGCAGC/TGGAGT 15 R W int1 mis11Minor allele frequency- T:0.02WA 118
rs1131725261,2
C--81841421(+) CTGTC-/AAAAAA 15 E R int1 fra11Minor allele frequency- A:0.50CSA 2

HapMap Linkage Disequilibrium report for TMEM254 (81838402 - 81852313 bp)

Structural Variations
      Database of Genomic Variants (DGV) variations for TMEM254: --
Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing TMEM254
DNA2.0 Custom Variant and Variant Library Synthesis for TMEM254

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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  --

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for TMEM254 gene integrated from 10 sources:
(articles sorted by number of sources associating them with TMEM254)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2, 3 Ota T.... Sugano S. (Nat. Genet. 2004)
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  3. The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (Nature 2004)
  4. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
  5. Genome-wide association analysis of blood biomarkers in chronic obstructive pulmonary disease. (PubMed id 23144326)1 Kim D.K....Silverman E.K. (Am. J. Respir. Crit. Care Med. 2012)
  6. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
  7. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)1 Grupe A....Goate A. (Am. J. Hum. Genet. 2006)
  8. Lineage-specific gene duplication and loss in human and great ape evolution. (PubMed id 15252450)1 Fortna A....Sikela J.M. (PLoS Biol. 2004)
  9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
  10. Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. (PubMed id 8125298)1 Maruyama K. and Sugano S. (Gene 1994)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 80195 HGNC: 25804 AceView: C10orf57 Ensembl:ENSG00000133678 euGenes: HUgn80195
ECgene: TMEM254 H-InvDB: TMEM254

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for TMEM254 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for TMEM254 gene:
Search GeneIP for patents involving TMEM254

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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 EMD Millipore genomic analysis products

  
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 Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for TMEM254  
 OriGene qPCR primer pairs and template standards for TMEM254   OriGene Protein Over-expression Lysate for TMEM254  
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 OriGene qSTAR qPCR primer pairs in human, mouse for TMEM254   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
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 OriGene Custom Antibody Services for TMEM254   OriGene Custom Protein Services for TMEM254  

 
 
 Block miRNA regulation of human, mouse, rat TMEM254 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing TMEM254
 DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TMEM254 Predesigned siRNA for gene silencing in human, mouse, rat TMEM254
 QuantiFast Probe-based Assays in human, mouse, rat TMEM254 QuantiTect SYBR Green Assays in human, mouse, rat TMEM254
 Custom PCR Arrays for TMEM254 Search Chromatin IP Primers for TMEM254
 Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat TMEM254 Search GeneGlobe Interaction Network for TMEM254
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 GenScript Custom Purified and Recombinant Proteins Services for TMEM254 GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for TMEM254
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 Search Tocris compounds for TMEM254 (TM254)
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 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

 Novus Tissue Slides
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 Search for Antibodies for TMEM254 at Abcam
 See all of Abcam's Antibodies, Kits and Proteins for TMEM254
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 Browse ProSpec Recombinant Proteins
 Browse Proteins at Cloud-Clone Corp.
 Browse Antibodies at Cloud-Clone Corp.
 Browse ELISAs at Cloud-Clone Corp.
 Browse CLIAs at Cloud-Clone Corp.



 Browse ESI BIO Cell Lines and PureStem Progenitors for TMEM254
 Gene Synthesis
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 Variant Library Synthesis
 Codon Optimization
 Protein Production and Purification
 Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM254
 SwitchGear 3'UTR luciferase reporter plasmids for TMEM254
 Browse SwitchGear Promoter luciferase reporter plasmids for TMEM254
 Search ThermoFisher Antibodies for TMEM254
 Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM254
 inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TMEM254
 inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TMEM254
 LSBio Antibodies in human, mouse, rat for TMEM254
 Browse compounds at ApexBio
 Search Addgene for plasmids for TMEM254
  Search eBioscience for proteins for TMEM254
  Search eBioscience for elisas for TMEM254
  eBioscience FlowRNA Probe Sets
Customized transgenic rodents for:
 Humanization
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 antibodies-online antibodies for TMEM254 (11 products)
 antibodies-online kits for TMEM254 (2 products)
 antibodies-online peptides for TMEM254
  Search antibodies-online for proteins for TMEM254
       
GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 7 Oct 2014

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