Free for academic non-profit institutions. Other users need a Commercial license

Aliases for TMEM252 Gene

Aliases for TMEM252 Gene

  • Transmembrane Protein 252 2 3
  • C9orf71 3 4
  • Chromosome 9 Open Reading Frame 71 2
  • Transmembrane Protein C9orf71 3

External Ids for TMEM252 Gene

Previous Symbols for TMEM252 Gene

  • C9orf71

Summaries for TMEM252 Gene

GeneCards Summary for TMEM252 Gene

TMEM252 (Transmembrane Protein 252) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM252 Gene

Genomics for TMEM252 Gene

Genomic Location for TMEM252 Gene

Start:
68,536,580 bp from pter
End:
68,540,867 bp from pter
Size:
4,288 bases
Orientation:
Minus strand

Genomic View for TMEM252 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMEM252 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM252 Gene

No data available for Regulatory Elements for TMEM252 Gene

Proteins for TMEM252 Gene

  • Protein details for TMEM252 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N6L7-TM252_HUMAN
    Recommended name:
    Transmembrane protein 252
    Protein Accession:
    Q8N6L7
    Secondary Accessions:

    Protein attributes for TMEM252 Gene

    Size:
    170 amino acids
    Molecular mass:
    18703 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMEM252 Gene

Proteomics data for TMEM252 Gene at MOPED

Post-translational modifications for TMEM252 Gene

No Post-translational modifications

Other Protein References for TMEM252 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TMEM252 Gene

Domains for TMEM252 Gene

Protein Domains for TMEM252 Gene

ProtoNet:
genes like me logo Genes that share domains with TMEM252: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TMEM252 Gene

Function for TMEM252 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TMEM252 Gene

Localization for TMEM252 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM252 Gene

Membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for TMEM252 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM252: view

Pathways for TMEM252 Gene

SuperPathways for TMEM252 Gene

No Data Available

Interacting Proteins for TMEM252 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000366528%0d%0a9606.ENSP00000358081%0d%0a
Selected Interacting proteins: ENSP00000366528 for TMEM252 Gene via STRING

Symbol External ID(s) Details
BAG3

Gene Ontology (GO) - Biological Process for TMEM252 Gene

None

No data available for Pathways by source for TMEM252 Gene

Transcripts for TMEM252 Gene

mRNA/cDNA for TMEM252 Gene

(2) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(43) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TMEM252 Gene

Transmembrane protein 252:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM252 Gene

No ASD Table

Relevant External Links for TMEM252 Gene

GeneLoc Exon Structure for
TMEM252
ECgene alternative splicing isoforms for
TMEM252

Expression for TMEM252 Gene

mRNA expression in normal human tissues for TMEM252 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for TMEM252 Gene

This gene is overexpressed in Kidney - Cortex (15.1) and Colon - Sigmoid (4.6).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for TMEM252 Gene

SOURCE GeneReport for Unigene cluster for TMEM252 Gene Hs.663056

genes like me logo Genes that share expressions with TMEM252: view

Orthologs for TMEM252 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TMEM252 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TMEM252 36
  • 99.8 (n)
  • 99.41 (a)
TMEM252 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia LOC614257 36
  • 78.82 (n)
  • 66.47 (a)
TMEM252 37
  • 65 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TMEM252 36
  • 79.02 (n)
  • 72.94 (a)
TMEM252 37
  • 73 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tmem252 36
  • 74.19 (n)
  • 67.68 (a)
Tmem252 16
Tmem252 37
  • 61 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia TMEM252 37
  • 54 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia TMEM252 37
  • 45 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Tmem252 36
  • 71.95 (n)
  • 65.24 (a)
chicken
(Gallus gallus)
Aves LOC100859235 36
  • 53.79 (n)
  • 40 (a)
TMEM252 37
  • 32 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia TMEM252 37
  • 38 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia tmem252 36
  • 53.96 (n)
  • 41.25 (a)
Species with no ortholog for TMEM252:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TMEM252 Gene

ENSEMBL:
Gene Tree for TMEM252 (if available)
TreeFam:
Gene Tree for TMEM252 (if available)

Paralogs for TMEM252 Gene

No data available for Paralogs for TMEM252 Gene

Variants for TMEM252 Gene

Sequence variations from dbSNP and Humsavar for TMEM252 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
rs265076 -- 68,536,318(-) AATTT(A/C)TTGTG downstream-variant-500B
rs398222 -- 68,538,146(-) CCGAA(C/T)GAATG intron-variant
rs404994 -- 68,538,150(-) GCCCC(C/T)GAATG intron-variant
rs4317642 -- 68,541,088(+) GTGGG(A/T)CACTC upstream-variant-2KB
rs4489377 -- 68,542,394(+) TATTG(C/T)CCTCT upstream-variant-2KB

Relevant External Links for TMEM252 Gene

HapMap Linkage Disequilibrium report
TMEM252

No data available for Structural Variations from Database of Genomic Variants (DGV) for TMEM252 Gene

Disorders for TMEM252 Gene

No disorders were found for TMEM252 Gene.

No data available for UniProtKB/Swiss-Prot for TMEM252 Gene

Publications for TMEM252 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Bcl2-associated athanogene 3 interactome analysis reveals a new role in modulating proteasome activity. (PMID: 23824909) Chen Y. … Ge F. (Mol. Cell Proteomics 2013) 3

Products for TMEM252 Gene

Sources for TMEM252 Gene

Back to Top

Content