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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

TMEM25 Gene

protein-coding GIFtS: 48
GCID: GC11P118401

transmembrane protein 25

Explore 1 disease affiliated with
TMEM25 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Transmembrane Protein 25¹ ²
FLJ14399¹
0610039J01Rik²

External Ids:	HGNC: 25890¹	Entrez Gene: 84866²	Ensembl: ENSG00000149582⁷	OMIM: 613934⁵	UniProtKB: Q86YD3³

Export aliases for TMEM25 gene to outside databases

Previous GC identifers: GC11P117941 GC11P117907 GC11P114338

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Gene Wiki entry for TMEM25

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000011.9 NC_018922.1 NT_033899.8

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the TMEM25 gene promoter:
STAT5B HOXA9B HOXA9 Sp1 CUTL1 C/EBPalpha Meis-1b Chx10 Pax-4a Meis-1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: TMEM25 promoter sequence

Search SABiosciences Chromatin IP Primers for TMEM25

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TMEM25

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q23.3 Ensembl cytogenetic band: 11q23.3 HGNC cytogenetic band: 11q23.3

TMEM25 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMEM25 gene location

GeneLoc information about chromosome 11 GeneLoc Exon Structure

GeneLoc location for GC11P118401: view genomic region (about GC identifiers)

Start:	118,401,756 bp from pter	End:	118,417,995 bp from pter
Size:	16,240 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: TMM25_HUMAN, Q86YD3 (See protein sequence)

Recommended Name: Transmembrane protein 25 precursor

Size: 366 amino acids; 39285 Da

Subcellular location: Isoform 1: Cell membrane; Single-pass type I membrane protein (Potential)

Subcellular location: Isoform 4: Cell membrane; Single-pass type I membrane protein (Potential)

Subcellular location: Isoform 2: Secreted (Potential)

Subcellular location: Isoform 3: Secreted (Potential)

Secondary accessions: A8K8J4 B0YJA6 B0YJA7 B0YJA9 G5E9U4 Q6UW89 Q86UA7 Q8NBL5 Q96KA6 Q96MW9

Alternative splicing: 5 isoforms: Q86YD3-1 Q86YD3-2 Q86YD3-3 Q86YD3-4 Q86YD3-5 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TMEM25: NX_Q86YD3

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q86YD3

TMEM25 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (6 alternative transcripts):

NP_001137506.1 NP_001137507.1 NP_001137508.1 NP_001137509.1 NP_001137510.1 NP_116169.2

ENSEMBL proteins:

ENSP00000411882 ENSP00000416071 ENSP00000433610 ENSP00000431663 ENSP00000432062

ENSP00000432040 ENSP00000346237 ENSP00000433938 ENSP00000433906 ENSP00000433059

ENSP00000278959 ENSP00000431548 ENSP00000315635 ENSP00000435446 ENSP00000431205

ENSP00000436746 ENSP00000431145 ENSP00000352924 ENSP00000439408

Human Recombinant Protein Products:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	OriGene Purified Protein: TMEM25 OriGene Protein Over-expression Lysate: TMEM25 OriGene Custom Protein Services for TMEM25
	GenScript Custom Purified and Recombinant Proteins Services for TMEM25
	Novus Biologicals TMEM25 Lysate
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for TMEM25

Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005576	extracellular region	IEA	--
GO:0005886	plasma membrane	IEA	--
GO:0016020	membrane	--	--
GO:0016021	integral to membrane	IEA	--

TMEM25 for ontologies About GeneDecksing

TMEM25 Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies OriGene Custom Antibody Services for TMEM25
	GenScript Custom Superior Antibodies Services for TMEM25
	Novus Biologicals TMEM25 Antibody
	Search for Antibodies for TMEM25 at Abcam
	Uscn Antibodies for TMEM25
	Search ThermoFisher Antibodies for TMEM25

Assay Products for TMEM25:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for TMEM25
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for TMEM25

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

TMEM25 for domains About GeneDecksing

3 InterPro domains/families:

IPR007110 Ig-like_dom

IPR013162 CD80_C2-set

IPR013783 Ig-like_fold

Graphical View of Domain Structure for InterPro Entry Q86YD3

ProtoNet protein and cluster: Q86YD3

UniProtKB/Swiss-Prot: TMM25_HUMAN, Q86YD3

Similarity: Contains 1 Ig-like (immunoglobulin-like) domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

miRNA Products:		OriGene 3'-UTR Clone (see all 6): TMEM25 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TMEM25
		8/38 QIAGEN miScript miRNA Assays for microRNAs that regulate TMEM25 (see all 38):
		hsa-miR-520e hsa-miR-302d hsa-miR-106a hsa-miR-128 hsa-miR-218 hsa-miR-372 hsa-miR-93 hsa-miR-302b

		SwitchGear 3'UTR luciferase reporter plasmid: TMEM25 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TMEM25 (see all 7) OriGene shRNA RFP: TMEM25 Browse OriGene siRNA
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TMEM25

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for TMEM25

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TMEM25 (see all 9) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TMEM25 (see all 6) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 6): TMEM25 (NM_032780)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM25
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM25

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for TMEM25
		Search LifeMap BioReagents cell lines for TMEM25

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM25

2 GenomeRNAi human phenotypes for TMEM25:

Decreased BPV1 E2 protein expr

Increased HPV18 LCR reporter a

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for TMEM25

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

2 Interacting proteins for TMEM25 (Q86YD3^{2, 3} ENSP00000315635⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
SUMO1	P63165³, ENSP00000376076⁴	I2D: score=1 STRING: ENSP00000376076
--	XM_292512.3²	MINT-2877636

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for TMEM25
Search CenterWatch for drugs/clinical trials and news about TMEM25 / TMM25

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for TMEM25 gene (6 alternative transcripts):

NM_001144034.1 NM_001144035.1 NM_001144036.1 NM_001144037.1 NM_001144038.1 NM_032780.3

Unigene Cluster for TMEM25:

Transmembrane protein 25

Hs.564188 [show with all ESTs]

Unigene Representative Sequence: NM_032780

18/32 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 32):

ENST00000411589(uc009zad.3) ENST00000442938(uc001ptl.2 uc001ptm.2)

ENST00000526941 ENST00000526465 ENST00000527785 ENST00000525118 ENST00000534181

ENST00000528373 ENST00000354284 ENST00000529176 ENST00000530423 ENST00000533137

ENST00000533587 ENST00000529001(uc010ryd.1) ENST00000532762 ENST00000526973

ENST00000354064 ENST00000533627

miRNA Products:		OriGene 3'-UTR Clone (see all 6): TMEM25 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TMEM25
		8/38 QIAGEN miScript miRNA Assays for microRNAs that regulate TMEM25 (see all 38):
		hsa-miR-520e hsa-miR-302d hsa-miR-106a hsa-miR-128 hsa-miR-218 hsa-miR-372 hsa-miR-93 hsa-miR-302b

		SwitchGear 3'UTR luciferase reporter plasmid: TMEM25 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TMEM25 (see all 7) OriGene shRNA RFP: TMEM25 Browse OriGene siRNA
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TMEM25

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TMEM25 (see all 9) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TMEM25 (see all 6) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 6): TMEM25 (NM_032780)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM25
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM25

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TMEM25 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat TMEM25
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMEM25
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMEM25

Additional cDNA sequence:

AK027305.1 AK056325.1 AK075437.1 AK225415.1 AK292359.1 AK293670.1 AK297255.1 AY358919.1

BC036433.1 BC042896.1 BC051841.1

24/28 DOTS entries (see all 28):

DT.100787805 DT.101984160 DT.120717148 DT.100787806 DT.213383 DT.120717270 DT.120717200 DT.100787814

DT.95277310 DT.120717134 DT.100787812 DT.91727311 DT.120717178 DT.100787808 DT.100787815 DT.120717204

DT.120717342 DT.100787816 DT.120717242 DT.100787807 DT.120717186 DT.95236241 DT.120717188 DT.100787817

24/140 AceView cDNA sequences (see all 140):

NM_032780 BM757848 AW613509 CD634287 BI755230 CA411976 CR605433 AI658541

BQ575769 AY358919 BQ635863 BX460006 BF513120 AI084891 BP364901 BM767613

AI870598 BP362285 BU684634 BP358627 BI826047 BQ001717 CR621200 BI916135

GeneLoc Exon Structure

5/31 Alternative Splicing Database (ASD) splice patterns (SP) for TMEM25 (see all 31) About this scheme

ExUns:	1a	·	1b	·	1c	^	2a	·	2b	^	3	^	4a	·	4b	·	4c	^	5a	·	5b	^	6a	·	6b	^	7	^	8a	·	8b	·	8c	·	8d	·	8e	^	9a	·	9b	·	9c	^	10a	·	10b	^	11a	·	11b	·
SP1:																			-																		-
SP2:							-		-		-								-		-		-		-		-		-		-		-		-		-
SP3:																			-																		-
SP4:																																					-
SP5:							-		-		-								-		-		-		-		-		-		-						-

ExUns:	11c	·	11d	^	12a	·	12b	·	12c	·	12d	·	12e	·	12f	^	13	^	14	^	15	^	16	^	17
SP1:
SP2:					-		-		-		-		-		-
SP3:					-		-		-		-		-		-
SP4:					-		-		-		-		-		-
SP5:

ECgene alternative splicing isoforms for TMEM25

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

TMEM25 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTACTGCCTA

About this image

TMEM25 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

Mature follicles (In-vitro growth and ...)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See TMEM25 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TMEM25

SOURCE GeneReport for Unigene cluster: Hs.564188

SABiosciences Custom PCR Arrays for TMEM25

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TMEM25 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat TMEM25
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMEM25
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMEM25

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM25

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for TMEM25 gene from 2/9 species (see all 9) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Tmem25^{1 , 5}	transmembrane protein 25^{1, 5}	87.31(n)¹ 91.23(a)¹		9 (24.84 cM)⁵ 71687¹ NM_027865.2¹ NP_082141.1¹ 44793776⁵
zebrafish (Danio rerio)	Actinopterygii	CABZ01087566.1⁶	--	31(a)	1 ↔ 1	15(46543800-46545096)

ENSEMBL Gene Tree for TMEM25 (if available)
TreeFam Gene Tree for TMEM25 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 11 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs185069029^1,2		--	118399904(+)	`TATAGA/TTGAAG`	7	--	us2k¹ int¹		0	--	--	--	--
rs143362264^1,2		--	118399909(+)	`ATGAAG/TAAACT`	7	--	us2k¹ int¹		0	--	--	--	--
rs188273097^1,2		--	118399931(+)	`AGGCTA/GAGTAA`	7	--	us2k¹ int¹		0	--	--	--	--
rs61900947^1,2	C,	--	118400225(+)	`NNNNTA/GATTAA`	7	--	us2k¹ int¹		2		NA	122
rs180970107^1,2		--	118400404(+)	`CCTCCC/GAGGAG`	7	--	int¹ us2k¹		0	--	--	--	--
rs77021820^1,2	F,	--	118400413(+)	`AGCCCC/TTTATC`	7	--	int¹ us2k¹		1		WA	118
rs113835012^1,2	C,	--	118400533(+)	`ACCAAG/AGAGTA`	7	--	us2k¹ int¹		1		CSA	2
rs139058287^1,2		--	118400698(+)	`CAAGTA/GTTTTA`	7	--	us2k¹ int¹		0	--	--	--	--
rs149899213^1,2		--	118400736(+)	`AGGCCA/CGCTCT`	7	--	int¹ us2k¹		0	--	--	--	--
rs144932732^1,2		--	118400787(+)	`AAGAAC/TGATGA`	7	--	us2k¹ int¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for TMEM25 (118401756 - 118417995 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for TMEM25: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TMEM25

DNA2.0 Custom Variant and Variant Library Synthesis for TMEM25

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

TMEM25 for disorders           About GeneDecksing

OMIM gene information: 613934    OMIM disorders: --

1 disease for TMEM25:    About MalaCards

breast cancer

Export disorders for TMEM25 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for TMEM25 gene, integrated from 9 sources (see all 13):
(articles sorted by number of sources associating them with TMEM25)

Utopia: connect your pdf to the dynamic
world of online information

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)^{1, 2, 3} Clark H.F.... Gray A.M. (2003)
Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)^{1, 2} Otsuki T....Isogai T. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Identification and characterization of human TMEM25 and mouse Tmem25 genes in silico. (PubMed id 15254712)^{1, 3} Katoh M. and Katoh M. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Signal peptide prediction based on analysis of experimentally verified cleavage sites. (PubMed id 15340161)^{1, 2} Zhang Z. and Henzel W.J. (2004)
TMEM25, REPS2 and Meis 1: favourable prognostic and p redictive biomarkers for breast cancer. (PubMed id 19776672)¹ Doolan P....O'Driscoll L. (2009)
Broad spectrum identification of SUMO substrates in m elanoma cells. (PubMed id 17549794)¹ Ganesan A.K....White M.A. (2007)
A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. (PubMed id 16713569)¹ Lim J.... Zoghbi H.Y. (2006)
Human chromosome 11 DNA sequence and analysis including novel gene identification. (PubMed id 16554811)² Taylor T.D....Sakaki Y. (2006)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 84866	HGNC: 25890	AceView: TMEM25	Ensembl:ENSG00000149582	euGenes: HUgn84866
ECgene: TMEM25	H-InvDB: TMEM25

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for TMEM25	Pharmacogenomics, SNPs, Pathways

Intellectual Property for TMEM25 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for TMEM25 gene:
Search GeneIP for patents involving TMEM25

GeneCards and IP:
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM25

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Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM25

GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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TMEM25 Gene

transmembrane protein 25

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TMEM25 Gene

transmembrane protein 25

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