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Aliases for TMEM249 Gene

Aliases for TMEM249 Gene

  • Transmembrane Protein 249 2 3
  • C8ORFK29 3 4
  • Putative Transmembrane Protein C8orfK29 3

External Ids for TMEM249 Gene

Previous GeneCards Identifiers for TMEM249 Gene

  • GC08M145577

Summaries for TMEM249 Gene

GeneCards Summary for TMEM249 Gene

TMEM249 (Transmembrane Protein 249) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM249 Gene

Genomics for TMEM249 Gene

Genomic Location for TMEM249 Gene

Start:
144,353,226 bp from pter
End:
144,355,609 bp from pter
Size:
2,384 bases
Orientation:
Minus strand

Genomic View for TMEM249 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMEM249 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM249 Gene

No data available for Regulatory Elements for TMEM249 Gene

Proteins for TMEM249 Gene

  • Protein details for TMEM249 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q2WGJ8-TM249_HUMAN
    Recommended name:
    Transmembrane protein 249
    Protein Accession:
    Q2WGJ8
    Secondary Accessions:

    Protein attributes for TMEM249 Gene

    Size:
    235 amino acids
    Molecular mass:
    27046 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMEM249 Gene

Proteomics data for TMEM249 Gene at MOPED

Post-translational modifications for TMEM249 Gene

  • Glycosylation at Asn38 and Asn115

Other Protein References for TMEM249 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TMEM249 Gene

Domains for TMEM249 Gene

Protein Domains for TMEM249 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TMEM249: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for TMEM249 Gene

Function for TMEM249 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TMEM249 Gene

Localization for TMEM249 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM249 Gene

Membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for TMEM249 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM249: view

No data available for Subcellular locations from COMPARTMENTS for TMEM249 Gene

Pathways for TMEM249 Gene

SuperPathways for TMEM249 Gene

No Data Available

Interacting Proteins for TMEM249 Gene

Gene Ontology (GO) - Biological Process for TMEM249 Gene

None

No data available for Pathways by source for TMEM249 Gene

Transcripts for TMEM249 Gene

mRNA/cDNA for TMEM249 Gene

Unigene Clusters for TMEM249 Gene

Transmembrane protein 249:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TMEM249

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM249 Gene

No ASD Table

Relevant External Links for TMEM249 Gene

GeneLoc Exon Structure for
TMEM249
ECgene alternative splicing isoforms for
TMEM249

Expression for TMEM249 Gene

mRNA expression in normal human tissues for TMEM249 Gene

SOURCE GeneReport for Unigene cluster for TMEM249 Gene Hs.122231

genes like me logo Genes that share expressions with TMEM249: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for TMEM249 Gene

Orthologs for TMEM249 Gene

This gene was present in the common ancestor of mammals.

Orthologs for TMEM249 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TMEM249 35
  • 98.21 (n)
  • 97.31 (a)
cow
(Bos Taurus)
Mammalia TMEM249 35
  • 85.42 (n)
  • 82.21 (a)
dog
(Canis familiaris)
Mammalia TMEM249 35
  • 81.83 (n)
  • 73.82 (a)
mouse
(Mus musculus)
Mammalia Gm8140 35
  • 75.77 (n)
  • 71.76 (a)
rat
(Rattus norvegicus)
Mammalia Tmem249 35
  • 73.3 (n)
  • 67.7 (a)
Species with no ortholog for TMEM249:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TMEM249 Gene

ENSEMBL:
Gene Tree for TMEM249 (if available)
TreeFam:
Gene Tree for TMEM249 (if available)

Paralogs for TMEM249 Gene

No data available for Paralogs for TMEM249 Gene

Variants for TMEM249 Gene

Sequence variations from dbSNP and Humsavar for TMEM249 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type MAF
rs880701 -- 144,354,164(+) CCACG(C/G)GGAGA intron-variant
rs880702 -- 144,354,169(+) CGGAG(A/C)GTCTG intron-variant
rs2272663 -- 144,354,636(-) CCATT(C/T)GTGCA reference, synonymous-codon, nc-transcript-variant
rs2272664 -- 144,354,339(-) GCGCC(A/T)CCCCC intron-variant
rs4279638 -- 144,353,880(-) GCTAA(G/T)TCCGC intron-variant

Relevant External Links for TMEM249 Gene

HapMap Linkage Disequilibrium report
TMEM249

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for TMEM249 Gene

Disorders for TMEM249 Gene

No disorders were found for TMEM249 Gene.

No data available for UniProtKB/Swiss-Prot for TMEM249 Gene

Publications for TMEM249 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  2. DNA sequence and analysis of human chromosome 8. (PMID: 16421571) Nusbaum C. … Lander E.S. (Nature 2006) 4

Products for TMEM249 Gene

Sources for TMEM249 Gene

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