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Aliases for TMEM247 Gene

Aliases for TMEM247 Gene

  • Transmembrane Protein 247 2 3

External Ids for TMEM247 Gene

Previous GeneCards Identifiers for TMEM247 Gene

  • GC02P046657

Summaries for TMEM247 Gene

GeneCards Summary for TMEM247 Gene

TMEM247 (Transmembrane Protein 247) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM247 Gene

Genomics for TMEM247 Gene

Genomic Location for TMEM247 Gene

46,429,190 bp from pter
46,484,579 bp from pter
55,390 bases
Plus strand

Genomic View for TMEM247 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMEM247 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM247 Gene

No data available for Regulatory Elements for TMEM247 Gene

Proteins for TMEM247 Gene

  • Protein details for TMEM247 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Transmembrane protein 247
    Protein Accession:

    Protein attributes for TMEM247 Gene

    219 amino acids
    Molecular mass:
    25168 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMEM247 Gene

Proteomics data for TMEM247 Gene at MOPED

Post-translational modifications for TMEM247 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TMEM247 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TMEM247 Gene

Domains & Families for TMEM247 Gene

Protein Domains for TMEM247 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TMEM247: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for TMEM247 Gene

Function for TMEM247 Gene

Phenotypes for TMEM247 Gene

GenomeRNAi human phenotypes for TMEM247:
genes like me logo Genes that share phenotypes with TMEM247: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TMEM247

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TMEM247 Gene

Localization for TMEM247 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM247 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for TMEM247 Gene COMPARTMENTS Subcellular localization image for TMEM247 gene
Compartment Confidence
endoplasmic reticulum 2

Gene Ontology (GO) - Cellular Components for TMEM247 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005783 endoplasmic reticulum IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM247: view

Pathways & Interactions for TMEM247 Gene

SuperPathways for TMEM247 Gene

No Data Available

Interacting Proteins for TMEM247 Gene

Gene Ontology (GO) - Biological Process for TMEM247 Gene


No data available for Pathways by source and SIGNOR curated interactions for TMEM247 Gene

Drugs & Compounds for TMEM247 Gene

No Compound Related Data Available

Transcripts for TMEM247 Gene

mRNA/cDNA for TMEM247 Gene

(2) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(4) Selected AceView cDNA sequences:
(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TMEM247 Gene

Transmembrane protein 247:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TMEM247

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM247 Gene

No ASD Table

Relevant External Links for TMEM247 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TMEM247 Gene

mRNA expression in normal human tissues for TMEM247 Gene

mRNA differential expression in normal tissues according to GTEx for TMEM247 Gene

This gene is overexpressed in Testis (x52.8).

Protein differential expression in normal tissues from HIPED for TMEM247 Gene

This gene is overexpressed in Testis (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for TMEM247 Gene

SOURCE GeneReport for Unigene cluster for TMEM247 Gene Hs.733348

genes like me logo Genes that share expression patterns with TMEM247: view

Protein tissue co-expression partners for TMEM247 Gene

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for TMEM247 Gene

Orthologs for TMEM247 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TMEM247 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia TMEM247 35
  • 87.06 (n)
  • 82.04 (a)
TMEM247 36
  • 76 (a)
(Canis familiaris)
Mammalia TMEM247 35
  • 85.28 (n)
  • 82.52 (a)
TMEM247 36
  • 78 (a)
(Mus musculus)
Mammalia Tmem247 35
  • 75.76 (n)
  • 69.38 (a)
Tmem247 16
Tmem247 36
  • 67 (a)
(Pan troglodytes)
Mammalia TMEM247 35
  • 97.55 (n)
  • 94.95 (a)
TMEM247 36
  • 92 (a)
(Rattus norvegicus)
Mammalia Tmem247 35
  • 79.13 (n)
  • 72.82 (a)
(Anolis carolinensis)
Reptilia TMEM247 36
  • 24 (a)
Species with no ortholog for TMEM247:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TMEM247 Gene

Gene Tree for TMEM247 (if available)
Gene Tree for TMEM247 (if available)

Paralogs for TMEM247 Gene

No data available for Paralogs for TMEM247 Gene

Variants for TMEM247 Gene

Sequence variations from dbSNP and Humsavar for TMEM247 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs1052423 -- 46,480,667(+) CCAGC(A/G)GCAGC missense, reference
rs2121697 -- 46,482,468(-) GGGGG(G/T)AAAAT intron-variant
rs2121698 -- 46,482,432(-) CCAAA(A/G)GCATA intron-variant
rs3053620 -- 46,480,201(+) TATTA(-/ATA/ATC)CTTTG intron-variant
rs3814046 -- 46,479,582(-) ATCCA(C/G)AAAAC utr-variant-5-prime

Variation tolerance for TMEM247 Gene

Gene Damage Index Score: 6.26; 76.32% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TMEM247 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for TMEM247 Gene

Disorders for TMEM247 Gene

Relevant External Links for TMEM247

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with TMEM247: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TMEM247 Gene

Publications for TMEM247 Gene

  1. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 67

Products for TMEM247 Gene

Sources for TMEM247 Gene

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