Free for academic non-profit institutions. Other users need a Commercial license

Aliases for TMEM243 Gene

Aliases for TMEM243 Gene

  • Transmembrane Protein 243, Mitochondrial 2 3
  • C7orf23 3 4
  • MDR1 And Mitochondrial Taxol Resistance Associated Gene 2
  • MDR1 And Mitochondrial Taxol Resistance Associated 3
  • Chromosome 7 Open Reading Frame 23 2
  • Transmembrane Protein C7orf23 3
  • Transmembrane Protein 243 3
  • MM-TRAG 3

External Ids for TMEM243 Gene

Previous HGNC Symbols for TMEM243 Gene

  • C7orf23

Previous GeneCards Identifiers for TMEM243 Gene

  • GC07M086826

Summaries for TMEM243 Gene

GeneCards Summary for TMEM243 Gene

TMEM243 (Transmembrane Protein 243, Mitochondrial) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM243 Gene

Genomics for TMEM243 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for TMEM243 Gene

87,196,160 bp from pter
87,220,587 bp from pter
24,428 bases
Minus strand

Genomic View for TMEM243 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMEM243 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM243 Gene

No data available for Regulatory Elements for TMEM243 Gene

Proteins for TMEM243 Gene

  • Protein details for TMEM243 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Transmembrane protein 243
    Protein Accession:
    Secondary Accessions:
    • A4D1C6
    • B2R9I4
    • D6W5P1

    Protein attributes for TMEM243 Gene

    118 amino acids
    Molecular mass:
    13391 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMEM243 Gene

Proteomics data for TMEM243 Gene at MOPED

Post-translational modifications for TMEM243 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TMEM243 Gene

No data available for DME Specific Peptides for TMEM243 Gene

Domains for TMEM243 Gene

Protein Domains for TMEM243 Gene


Graphical View of Domain Structure for InterPro Entry



  • Q9BU79
  • Belongs to the TMEM243 family.
genes like me logo Genes that share domains with TMEM243: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for TMEM243 Gene

Function for TMEM243 Gene

Animal Model Products

CRISPR Products

miRNA for TMEM243 Gene

miRTarBase miRNAs that target TMEM243

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TMEM243

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for TMEM243 Gene

Localization for TMEM243 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM243 Gene

Membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for TMEM243 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM243: view

No data available for Subcellular locations from COMPARTMENTS for TMEM243 Gene

Pathways for TMEM243 Gene

SuperPathways for TMEM243 Gene

No Data Available

Interacting Proteins for TMEM243 Gene

Gene Ontology (GO) - Biological Process for TMEM243 Gene


No data available for Pathways by source for TMEM243 Gene

Transcripts for TMEM243 Gene

Unigene Clusters for TMEM243 Gene

Transmembrane protein 243, mitochondrial:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TMEM243

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM243 Gene

ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b
SP1: -
SP2: - -
SP3: -
SP4: - -

Relevant External Links for TMEM243 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TMEM243 Gene

mRNA expression in normal human tissues for TMEM243 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues for TMEM243 Gene

This gene is overexpressed in Blymphocyte (58.4) and NK cells (10.6).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for TMEM243 Gene

SOURCE GeneReport for Unigene cluster for TMEM243 Gene Hs.619593

genes like me logo Genes that share expressions with TMEM243: view

Expression partners for TMEM243 Gene

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for TMEM243 Gene

Orthologs for TMEM243 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TMEM243 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia TMEM243 35
  • 94.07 (n)
  • 96.61 (a)
TMEM243 36
  • 92 (a)
(Canis familiaris)
Mammalia C14H7orf23 35
  • 86.42 (n)
  • 87.04 (a)
TMEM243 36
  • 91 (a)
(Mus musculus)
Mammalia Tmem243 35
  • 94.07 (n)
  • 97.46 (a)
Tmem243 16
Tmem243 36
  • 93 (a)
(Pan troglodytes)
Mammalia C7H7orf23 35
  • 99.72 (n)
  • 100 (a)
TMEM243 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Tmem243 35
  • 90.96 (n)
  • 94.92 (a)
(Monodelphis domestica)
Mammalia TMEM243 36
  • 92 (a)
(Ornithorhynchus anatinus)
Mammalia TMEM243 36
  • 85 (a)
(Gallus gallus)
Aves C7ORF23 35
  • 82.44 (n)
  • 81.72 (a)
TMEM243 36
  • 76 (a)
(Anolis carolinensis)
Reptilia TMEM243 36
  • 80 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia tmem243 35
  • 73.73 (n)
  • 79.66 (a)
(Danio rerio)
Actinopterygii tmem243b 35
  • 70.06 (n)
  • 78.81 (a)
tmem243a 36
  • 42 (a)
tmem243b 36
  • 70 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 44 (a)
Species with no ortholog for TMEM243:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TMEM243 Gene

Gene Tree for TMEM243 (if available)
Gene Tree for TMEM243 (if available)

Paralogs for TMEM243 Gene

No data available for Paralogs for TMEM243 Gene

Variants for TMEM243 Gene

Sequence variations from dbSNP and Humsavar for TMEM243 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type MAF
rs757961 -- 87,220,194(+) TGGAT(C/T)CCCTC upstream-variant-2KB, utr-variant-5-prime, intron-variant
rs886787 -- 87,220,894(+) TTGTT(C/T)GCATG upstream-variant-2KB
rs1062274 -- 87,214,559(-) AGGTG(A/G)TGTGG intron-variant
rs2057984 -- 87,197,224(+) TTCTT(C/T)TTCGG intron-variant, downstream-variant-500B
rs2190424 -- 87,212,655(+) CACCA(C/T)TTCCT intron-variant

Relevant External Links for TMEM243 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for TMEM243 Gene

Disorders for TMEM243 Gene

No disorders were found for TMEM243 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for TMEM243 Gene

Publications for TMEM243 Gene

  1. Human chromosome 7: DNA sequence and biology. (PMID: 12690205) Scherer S.W. … Tsui L.-C. (Science 2003) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. MM-TRAG (MGC4175), a novel intracellular mitochondrial protein, is associated with the taxol- and doxorubicin-resistant phenotype in human cancer cell lines. (PMID: 15556294) Duan Z. … Seiden M.V. (Gene 2004) 3 23
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Regional activation of chromosomal arm 7q with and without gene amplification in taxane-selected human ovarian cancer cell lines. (PMID: 16382445) Wang Y.C. … Sikic B.I. (Genes Chromosomes Cancer 2006) 3

Products for TMEM243 Gene

Sources for TMEM243 Gene

Back to Top