Free for academic non-profit institutions. Other users need a Commercial license

Aliases for TMEM243 Gene

Aliases for TMEM243 Gene

  • Transmembrane Protein 243, Mitochondrial 2 3
  • C7orf23 3 4
  • MDR1 And Mitochondrial Taxol Resistance Associated Gene 2
  • MDR1 And Mitochondrial Taxol Resistance Associated 3
  • Chromosome 7 Open Reading Frame 23 2
  • Transmembrane Protein C7orf23 3
  • Transmembrane Protein 243 3
  • MM-TRAG 3

External Ids for TMEM243 Gene

Previous Symbols for TMEM243 Gene

  • C7orf23

Summaries for TMEM243 Gene

GeneCards Summary for TMEM243 Gene

TMEM243 (Transmembrane Protein 243, Mitochondrial) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM243 Gene

Genomics for TMEM243 Gene

Genomic Location for TMEM243 Gene

Start:
87,196,160 bp from pter
End:
87,220,587 bp from pter
Size:
24,428 bases
Orientation:
Minus strand

Genomic View for TMEM243 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMEM243 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM243 Gene

No data available for Regulatory Elements for TMEM243 Gene

Proteins for TMEM243 Gene

  • Protein details for TMEM243 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9BU79-TM243_HUMAN
    Recommended name:
    Transmembrane protein 243
    Protein Accession:
    Q9BU79
    Secondary Accessions:
    • A4D1C6
    • B2R9I4
    • D6W5P1

    Protein attributes for TMEM243 Gene

    Size:
    118 amino acids
    Molecular mass:
    13391 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMEM243 Gene

Proteomics data for TMEM243 Gene at MOPED

Post-translational modifications for TMEM243 Gene

No Post-translational modifications

Other Protein References for TMEM243 Gene

No data available for DME Specific Peptides for TMEM243 Gene

Domains for TMEM243 Gene

Protein Domains for TMEM243 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

TM243_HUMAN
Family:
  • Belongs to the TMEM243 family.:
    • Q9BU79
genes like me logo Genes that share domains with TMEM243: view

No data available for Gene Families for TMEM243 Gene

Function for TMEM243 Gene

miRNA for TMEM243 Gene

miRTarBase miRNAs that target TMEM243

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for TMEM243 Gene

Localization for TMEM243 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM243 Gene

Membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for TMEM243 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM243: view

Pathways for TMEM243 Gene

SuperPathways for TMEM243 Gene

No Data Available

Interacting Proteins for TMEM243 Gene

Gene Ontology (GO) - Biological Process for TMEM243 Gene

None

No data available for Pathways by source for TMEM243 Gene

Transcripts for TMEM243 Gene

Unigene Clusters for TMEM243 Gene

Transmembrane protein 243, mitochondrial:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM243 Gene

ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b
SP1: -
SP2: - -
SP3: -
SP4: - -
SP5:

Relevant External Links for TMEM243 Gene

GeneLoc Exon Structure for
TMEM243
ECgene alternative splicing isoforms for
TMEM243

Expression for TMEM243 Gene

mRNA expression in normal human tissues for TMEM243 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for TMEM243 Gene

SOURCE GeneReport for Unigene cluster for TMEM243 Gene Hs.619593

genes like me logo Genes that share expressions with TMEM243: view

Orthologs for TMEM243 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TMEM243 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C7H7orf23 36
  • 99.72 (n)
  • 100 (a)
TMEM243 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia TMEM243 36
  • 94.07 (n)
  • 96.61 (a)
TMEM243 37
  • 92 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C14H7orf23 36
  • 86.42 (n)
  • 87.04 (a)
TMEM243 37
  • 91 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tmem243 36
  • 94.07 (n)
  • 97.46 (a)
Tmem243 16
Tmem243 37
  • 93 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia TMEM243 37
  • 92 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia TMEM243 37
  • 85 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Tmem243 36
  • 90.96 (n)
  • 94.92 (a)
chicken
(Gallus gallus)
Aves C7ORF23 36
  • 82.44 (n)
  • 81.72 (a)
TMEM243 37
  • 76 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia TMEM243 37
  • 80 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia tmem243 36
  • 73.73 (n)
  • 79.66 (a)
zebrafish
(Danio rerio)
Actinopterygii tmem243a 37
  • 42 (a)
OneToMany
tmem243b 36
  • 70.06 (n)
  • 78.81 (a)
tmem243b 37
  • 70 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 44 (a)
OneToOne
Species with no ortholog for TMEM243:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TMEM243 Gene

ENSEMBL:
Gene Tree for TMEM243 (if available)
TreeFam:
Gene Tree for TMEM243 (if available)

Paralogs for TMEM243 Gene

No data available for Paralogs for TMEM243 Gene

Variants for TMEM243 Gene

Sequence variations from dbSNP and Humsavar for TMEM243 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type MAF
rs757961 -- 87,220,194(+) TGGAT(C/T)CCCTC upstream-variant-2KB, utr-variant-5-prime, intron-variant
rs886787 -- 87,220,894(+) TTGTT(C/T)GCATG upstream-variant-2KB
rs1062274 -- 87,214,559(-) AGGTG(A/G)TGTGG intron-variant
rs2057984 -- 87,197,224(+) TTCTT(C/T)TTCGG intron-variant, downstream-variant-500B
rs2190424 -- 87,212,655(+) CACCA(C/T)TTCCT intron-variant

Relevant External Links for TMEM243 Gene

HapMap Linkage Disequilibrium report
TMEM243

No data available for Structural Variations from Database of Genomic Variants (DGV) for TMEM243 Gene

Disorders for TMEM243 Gene

No disorders were found for TMEM243 Gene.

No data available for UniProtKB/Swiss-Prot for TMEM243 Gene

Publications for TMEM243 Gene

  1. Human chromosome 7: DNA sequence and biology. (PMID: 12690205) Scherer S.W. … Tsui L.-C. (Science 2003) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. MM-TRAG (MGC4175), a novel intracellular mitochondrial protein, is associated with the taxol- and doxorubicin-resistant phenotype in human cancer cell lines. (PMID: 15556294) Duan Z. … Seiden M.V. (Gene 2004) 3 23
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Regional activation of chromosomal arm 7q with and without gene amplification in taxane-selected human ovarian cancer cell lines. (PMID: 16382445) Wang Y.C. … Sikic B.I. (Genes Chromosomes Cancer 2006) 3

Products for TMEM243 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate TMEM243
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for TMEM243
    • Block miRNA regulation of TMEM243 using miScript Target Protectors

    Sources for TMEM243 Gene

    Back to Top

    Content