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Aliases for TMEM242 Gene

Aliases for TMEM242 Gene

  • Transmembrane Protein 242 2 3
  • C6orf35 3 4
  • UPF0463 Transmembrane Protein C6orf35 3
  • Chromosome 6 Open Reading Frame 35 2
  • BM033 3

External Ids for TMEM242 Gene

Previous Symbols for TMEM242 Gene

  • C6orf35

Summaries for TMEM242 Gene

GeneCards Summary for TMEM242 Gene

TMEM242 (Transmembrane Protein 242) is a Protein Coding gene.

Gene Wiki entry for TMEM242 Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM242 Gene

Genomics for TMEM242 Gene

Genomic Location for TMEM242 Gene

Start:
157,289,022 bp from pter
End:
157,324,221 bp from pter
Size:
35,200 bases
Orientation:
Minus strand

Genomic View for TMEM242 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMEM242 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM242 Gene

No data available for Regulatory Elements for TMEM242 Gene

Proteins for TMEM242 Gene

  • Protein details for TMEM242 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NWH2-TM242_HUMAN
    Recommended name:
    Transmembrane protein 242
    Protein Accession:
    Q9NWH2
    Secondary Accessions:
    • B9EJD0
    • Q9NZ88
    • Q9P094

    Protein attributes for TMEM242 Gene

    Size:
    141 amino acids
    Molecular mass:
    14758 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAF28965.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=AAF67621.1; Type=Frameshift; Positions=130; Evidence={ECO:0000305};

neXtProt entry for TMEM242 Gene

Proteomics data for TMEM242 Gene at MOPED

Post-translational modifications for TMEM242 Gene

No Post-translational modifications

Other Protein References for TMEM242 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TMEM242 Gene

Domains for TMEM242 Gene

Protein Domains for TMEM242 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

TM242_HUMAN
Family:
  • Belongs to the TMEM242 family.:
    • Q9NWH2
genes like me logo Genes that share domains with TMEM242: view

No data available for Gene Families for TMEM242 Gene

Function for TMEM242 Gene

Gene Ontology (GO) - Molecular Function for TMEM242 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with TMEM242: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TMEM242 Gene

Localization for TMEM242 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM242 Gene

Membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for TMEM242 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM242: view

Pathways for TMEM242 Gene

SuperPathways for TMEM242 Gene

No Data Available

Interacting Proteins for TMEM242 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000383594%0d%0a9606.ENSP00000338964%0d%0a9606.ENSP00000378426%0d%0a
Selected Interacting proteins: ENSP00000383594 Q9NWH2-TM242_HUMAN for TMEM242 Gene via STRING UniProtKB

Gene Ontology (GO) - Biological Process for TMEM242 Gene

None

No data available for Pathways by source for TMEM242 Gene

Transcripts for TMEM242 Gene

mRNA/cDNA for TMEM242 Gene

(1) REFSEQ mRNAs :
(6) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TMEM242 Gene

Transmembrane protein 242:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM242 Gene

No ASD Table

Relevant External Links for TMEM242 Gene

GeneLoc Exon Structure for
TMEM242
ECgene alternative splicing isoforms for
TMEM242

Expression for TMEM242 Gene

mRNA expression in normal human tissues for TMEM242 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for TMEM242 Gene

SOURCE GeneReport for Unigene cluster for TMEM242 Gene Hs.157212

genes like me logo Genes that share expressions with TMEM242: view

Orthologs for TMEM242 Gene

This gene was present in the common ancestor of animals.

Orthologs for TMEM242 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TMEM242 36
  • 97.64 (n)
  • 96.46 (a)
TMEM242 37
  • 88 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C9H6ORF35 37
  • 83 (a)
OneToOne
TMEM242 36
  • 85.05 (n)
  • 83.82 (a)
dog
(Canis familiaris)
Mammalia TMEM242 36
  • 87.71 (n)
  • 89.36 (a)
TMEM242 37
  • 89 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tmem242 36
  • 83.33 (n)
  • 86.43 (a)
Tmem242 16
Tmem242 37
  • 86 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia TMEM242 37
  • 76 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia C1H6orf35 36
  • 81.67 (n)
  • 83.57 (a)
chicken
(Gallus gallus)
Aves C3H6ORF35 36
  • 74.04 (n)
  • 79.51 (a)
TMEM242 37
  • 60 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia TMEM242 37
  • 72 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia tmem242 36
  • 65.25 (n)
  • 70.21 (a)
zebrafish
(Danio rerio)
Actinopterygii tmem242 36
  • 61.03 (n)
  • 63.08 (a)
tmem242 37
  • 58 (a)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP009165 36
  • 48.92 (n)
  • 46.77 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG11699 36
  • 47.62 (n)
  • 37.5 (a)
CG11699 37
  • 32 (a)
OneToOne
Species with no ortholog for TMEM242:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TMEM242 Gene

ENSEMBL:
Gene Tree for TMEM242 (if available)
TreeFam:
Gene Tree for TMEM242 (if available)

Paralogs for TMEM242 Gene

Pseudogenes.org Pseudogenes for TMEM242 Gene

genes like me logo Genes that share paralogs with TMEM242: view

No data available for Paralogs for TMEM242 Gene

Variants for TMEM242 Gene

Sequence variations from dbSNP and Humsavar for TMEM242 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs1133482 -- 157,323,976(-) CTGTT(A/G)GGAAG utr-variant-5-prime
rs1135259 -- 157,289,401(-) CATTA(A/G)ATGAT utr-variant-3-prime
rs1136157 -- 157,292,630(-) AAATG(A/G)TTCTG utr-variant-3-prime
rs1962087 -- 157,321,874(-) TTATA(G/T)AATGT intron-variant
rs3199374 -- 157,292,745(-) CAGGA(A/G)AGTAT utr-variant-3-prime

Relevant External Links for TMEM242 Gene

HapMap Linkage Disequilibrium report
TMEM242

No data available for Structural Variations from Database of Genomic Variants (DGV) for TMEM242 Gene

Disorders for TMEM242 Gene

No disorders were found for TMEM242 Gene.

No data available for UniProtKB/Swiss-Prot for TMEM242 Gene

Publications for TMEM242 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  3. Identification of VKORC1 interaction partners by split-ubiquitin system and coimmunoprecipitation. (PMID: 21103663) Schaafhausen A. … MA1ller C.R. (Thromb. Haemost. 2011) 3
  4. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  5. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 4

Products for TMEM242 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate TMEM242
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for TMEM242
    • Block miRNA regulation of TMEM242 using miScript Target Protectors

    Sources for TMEM242 Gene

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