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Aliases for TMEM241 Gene

Aliases for TMEM241 Gene

  • Transmembrane Protein 241 2 3
  • C18orf45 3 4 6
  • Putative Vertebrate Vrg4-Like Nucleotide-Sugar Transporter Truncated Variant2 3
  • Putative Vertebrate Vrg4-Like Nucleotide-Sugar Transporter Variant1 3
  • Chromosome 18 Open Reading Frame 45 2
  • Transmembrane Protein C18orf45 3
  • HVVT 3

External Ids for TMEM241 Gene

Previous HGNC Symbols for TMEM241 Gene

  • C18orf45

Previous GeneCards Identifiers for TMEM241 Gene

  • GC18M020777

Summaries for TMEM241 Gene

GeneCards Summary for TMEM241 Gene

TMEM241 (Transmembrane Protein 241) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM241 Gene

Genomics for TMEM241 Gene

Genomic Location for TMEM241 Gene

23,197,144 bp from pter
23,437,969 bp from pter
240,826 bases
Minus strand

Genomic View for TMEM241 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMEM241 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM241 Gene

No data available for Regulatory Elements for TMEM241 Gene

Proteins for TMEM241 Gene

  • Protein details for TMEM241 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Transmembrane protein 241
    Protein Accession:
    Secondary Accessions:
    • I0J130
    • Q6ZTS7
    • Q6ZW41

    Protein attributes for TMEM241 Gene

    296 amino acids
    Molecular mass:
    32647 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for TMEM241 Gene


neXtProt entry for TMEM241 Gene

Proteomics data for TMEM241 Gene at MOPED

Post-translational modifications for TMEM241 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for TMEM241 Gene

Domains for TMEM241 Gene

Protein Domains for TMEM241 Gene


Graphical View of Domain Structure for InterPro Entry



  • Belongs to the TMEM241 family.
  • Belongs to the TMEM241 family.
genes like me logo Genes that share domains with TMEM241: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for TMEM241 Gene

Function for TMEM241 Gene

Molecular function for TMEM241 Gene

UniProtKB/Swiss-Prot Induction:
Up-regulated by inducers of the unfolded protein response (UPR), including tunicamycin and thapsigargin.

Animal Model Products

CRISPR Products

miRNA for TMEM241 Gene

miRTarBase miRNAs that target TMEM241

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TMEM241

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for TMEM241 Gene

Localization for TMEM241 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM241 Gene

Membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for TMEM241 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM241: view

No data available for Subcellular locations from COMPARTMENTS for TMEM241 Gene

Pathways for TMEM241 Gene

SuperPathways for TMEM241 Gene

No Data Available

Interacting Proteins for TMEM241 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: Q24JQ0-TM241_HUMAN ENSP00000372720 for TMEM241 Gene via MINT STRING I2D

Gene Ontology (GO) - Biological Process for TMEM241 Gene


No data available for Pathways by source for TMEM241 Gene

Transcripts for TMEM241 Gene

Unigene Clusters for TMEM241 Gene

Transmembrane protein 241:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TMEM241

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM241 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15a · 15b · 15c ^ 16 ^ 17a · 17b
SP1: - - - - -
SP2: - - - - - - - -
SP3: - - -
SP4: -

Relevant External Links for TMEM241 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TMEM241 Gene

mRNA expression in normal human tissues for TMEM241 Gene

SOURCE GeneReport for Unigene cluster for TMEM241 Gene Hs.137562

genes like me logo Genes that share expressions with TMEM241: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for TMEM241 Gene

Orthologs for TMEM241 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TMEM241 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia TMEM241 35
  • 89.41 (n)
  • 88.18 (a)
TMEM241 36
  • 88 (a)
(Canis familiaris)
Mammalia TMEM241 35
  • 90.77 (n)
  • 88.18 (a)
TMEM241 36
  • 86 (a)
(Mus musculus)
Mammalia Tmem241 35
  • 85.75 (n)
  • 81.88 (a)
Tmem241 16
Tmem241 36
  • 82 (a)
(Pan troglodytes)
Mammalia TMEM241 35
  • 98.99 (n)
  • 97.3 (a)
TMEM241 36
  • 97 (a)
(Rattus norvegicus)
Mammalia Tmem241 35
  • 85.25 (n)
  • 82.09 (a)
(Monodelphis domestica)
Mammalia TMEM241 36
  • 76 (a)
(Ornithorhynchus anatinus)
Mammalia TMEM241 36
  • 65 (a)
(Gallus gallus)
Aves C2H18ORF45 35
  • 74.1 (n)
  • 68.92 (a)
(Anolis carolinensis)
Reptilia TMEM241 36
  • 66 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia tmem241 35
  • 70.87 (n)
  • 70.59 (a)
(Danio rerio)
Actinopterygii LOC101885957 35
  • 60.32 (n)
  • 56.35 (a)
TMEM241 (1 of 2) 36
  • 53 (a)
TMEM241 (2 of 2) 36
  • 54 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 23 (a)
Species with no ortholog for TMEM241:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TMEM241 Gene

Gene Tree for TMEM241 (if available)
Gene Tree for TMEM241 (if available)

Paralogs for TMEM241 Gene

(2) SIMAP similar genes for TMEM241 Gene using alignment to 9 proteins: Pseudogenes for TMEM241 Gene

genes like me logo Genes that share paralogs with TMEM241: view

No data available for Paralogs for TMEM241 Gene

Variants for TMEM241 Gene

Sequence variations from dbSNP and Humsavar for TMEM241 Gene

SNP ID Clin Chr 18 pos Sequence Context AA Info Type MAF
rs905069 -- 23,402,016(+) ACAGG(A/G)CCCCG intron-variant
rs930262 -- 23,304,707(-) TCCCC(C/G)CTCTT intron-variant
rs954166 -- 23,391,602(+) CCCAC(C/T)TCAGC intron-variant
rs954167 -- 23,391,781(+) cATGT(C/G)TAGAC intron-variant
rs1276318 -- 23,344,316(-) catgt(A/G)tgttc intron-variant

Relevant External Links for TMEM241 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for TMEM241 Gene

Disorders for TMEM241 Gene

No disorders were found for TMEM241 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for TMEM241 Gene

Publications for TMEM241 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Hyperactivity of the Ero1I+ oxidase elicits endoplasmic reticulum stress but no broad antioxidant response. (PMID: 23027870) Hansen H.G. … Ellgaard L. (J. Biol. Chem. 2012) 3 4
  3. Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci. (PMID: 23505323) Weissglas-Volkov D. … Pajukanta P. (J. Med. Genet. 2013) 3
  4. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4

Products for TMEM241 Gene

Sources for TMEM241 Gene

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