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Aliases for TMEM239 Gene

Aliases for TMEM239 Gene

  • Transmembrane Protein 239 2 3

External Ids for TMEM239 Gene

Previous GeneCards Identifiers for TMEM239 Gene

  • GC20P002806

Summaries for TMEM239 Gene

GeneCards Summary for TMEM239 Gene

TMEM239 (Transmembrane Protein 239) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM239 Gene

Genomics for TMEM239 Gene

Genomic Location for TMEM239 Gene

2,815,840 bp from pter
2,820,284 bp from pter
4,445 bases
Plus strand

Genomic View for TMEM239 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMEM239 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM239 Gene

No data available for Regulatory Elements for TMEM239 Gene

Proteins for TMEM239 Gene

  • Protein details for TMEM239 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Transmembrane protein 239
    Protein Accession:
    Secondary Accessions:
    • Q5JY54
    • Q6ZU23

    Protein attributes for TMEM239 Gene

    195 amino acids
    Molecular mass:
    21842 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAH21178.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for TMEM239 Gene


neXtProt entry for TMEM239 Gene

Proteomics data for TMEM239 Gene at MOPED

Post-translational modifications for TMEM239 Gene

No Post-translational modifications

Other Protein References for TMEM239 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TMEM239 Gene

Domains for TMEM239 Gene

Protein Domains for TMEM239 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TMEM239: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for TMEM239 Gene

Function for TMEM239 Gene

Gene Ontology (GO) - Molecular Function for TMEM239 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with TMEM239: view

Phenotypes for TMEM239 Gene

GenomeRNAi human phenotypes for TMEM239:
genes like me logo Genes that share phenotypes with TMEM239: view

Animal Model Products

miRNA for TMEM239 Gene

miRTarBase miRNAs that target TMEM239

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for TMEM239 Gene

Localization for TMEM239 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM239 Gene

Membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for TMEM239 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM239: view

No data available for Subcellular locations from COMPARTMENTS for TMEM239 Gene

Pathways for TMEM239 Gene

SuperPathways for TMEM239 Gene

No Data Available

Gene Ontology (GO) - Biological Process for TMEM239 Gene


No data available for Pathways by source for TMEM239 Gene

Transcripts for TMEM239 Gene

mRNA/cDNA for TMEM239 Gene

(4) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TMEM239 Gene

Transmembrane protein 239:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TMEM239

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM239 Gene

ExUns: 1a · 1b ^ 2a · 2b · 2c
SP2: -

Relevant External Links for TMEM239 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TMEM239 Gene

mRNA expression in normal human tissues for TMEM239 Gene

SOURCE GeneReport for Unigene cluster for TMEM239 Gene Hs.664180

genes like me logo Genes that share expressions with TMEM239: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for TMEM239 Gene

Orthologs for TMEM239 Gene

This gene was present in the common ancestor of mammals.

Orthologs for TMEM239 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia TMEM239 35
  • 85.87 (n)
  • 86.09 (a)
TMEM239 36
  • 65 (a)
(Canis familiaris)
Mammalia TMEM239 35
  • 87.42 (n)
  • 86.09 (a)
TMEM239 36
  • 66 (a)
(Mus musculus)
Mammalia Tmem239 35
  • 86.09 (n)
  • 84.11 (a)
Tmem239 16
Tmem239 36
  • 84 (a)
(Pan troglodytes)
Mammalia TMEM239 35
  • 98.71 (n)
  • 97.66 (a)
TMEM239 36
  • 73 (a)
(Rattus norvegicus)
Mammalia Tmem239 35
  • 87.64 (n)
  • 86.09 (a)
(Monodelphis domestica)
Mammalia TMEM239 36
  • 62 (a)
Species with no ortholog for TMEM239:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TMEM239 Gene

Gene Tree for TMEM239 (if available)
Gene Tree for TMEM239 (if available)

Paralogs for TMEM239 Gene

Selected SIMAP similar genes for TMEM239 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with TMEM239: view

No data available for Paralogs for TMEM239 Gene

Variants for TMEM239 Gene

Sequence variations from dbSNP and Humsavar for TMEM239 Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type MAF
rs215561 -- 2,816,369(+) AGGCC(A/G)TCCTG utr-variant-5-prime, missense, reference, intron-variant
rs6084178 -- 2,817,064(+) AGGGC(A/C)TGAGA utr-variant-3-prime, downstream-variant-500B
rs6107196 -- 2,816,735(+) AGCGC(C/T)TGCTG reference, synonymous-codon
rs6115683 -- 2,816,998(+) ACTCA(A/G)GATTT synonymous-codon, reference
rs6115684 -- 2,817,101(+) GATCA(A/G)GGCTC utr-variant-3-prime, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for TMEM239 Gene

Variant ID Type Subtype PubMed ID
nsv833895 CNV Loss 17160897
nsv522009 CNV Gain 19592680
nsv510780 CNV Loss 20534489
nsv518364 CNV Loss 19592680

Relevant External Links for TMEM239 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TMEM239 Gene

Disorders for TMEM239 Gene

No disorders were found for TMEM239 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for TMEM239 Gene

Publications for TMEM239 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  2. White matter integrity as an intermediate phenotype: exploratory genome-wide association analysis in individuals at high risk of bipolar disorder. (PMID: 23218918) Sprooten E. … McIntosh A.M. (Psychiatry Res 2013) 3
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  4. The DNA sequence and comparative analysis of human chromosome 20. (PMID: 11780052) Deloukas P. … Rogers J. (Nature 2001) 4
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4

Products for TMEM239 Gene

Sources for TMEM239 Gene

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