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Aliases for TMEM238 Gene

Aliases for TMEM238 Gene

  • Transmembrane Protein 238 2 3

External Ids for TMEM238 Gene

Previous GeneCards Identifiers for TMEM238 Gene

  • GC19M055891

Summaries for TMEM238 Gene

GeneCards Summary for TMEM238 Gene

TMEM238 (Transmembrane Protein 238) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM238 Gene

Genomics for TMEM238 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for TMEM238 Gene

55,379,244 bp from pter
55,384,598 bp from pter
5,355 bases
Minus strand

Genomic View for TMEM238 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for TMEM238 Gene

No data available for Regulatory Elements for TMEM238 Gene

Proteins for TMEM238 Gene

  • Protein details for TMEM238 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Transmembrane protein 238
    Protein Accession:

    Protein attributes for TMEM238 Gene

    176 amino acids
    Molecular mass:
    18040 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMEM238 Gene

Proteomics data for TMEM238 Gene at MOPED

Post-translational modifications for TMEM238 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TMEM238 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TMEM238 Gene

Domains & Families for TMEM238 Gene

Protein Domains for TMEM238 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TMEM238: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for TMEM238 Gene

Function for TMEM238 Gene

Animal Model Products

miRNA for TMEM238 Gene

miRTarBase miRNAs that target TMEM238

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TMEM238

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targets and HOMER Transcription for TMEM238 Gene

Localization for TMEM238 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM238 Gene

Membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for TMEM238 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM238: view

No data available for Subcellular locations from COMPARTMENTS for TMEM238 Gene

Pathways & Interactions for TMEM238 Gene

SuperPathways for TMEM238 Gene

No Data Available

Interacting Proteins for TMEM238 Gene

Gene Ontology (GO) - Biological Process for TMEM238 Gene


No data available for Pathways by source and SIGNOR curated interactions for TMEM238 Gene

Drugs & Compounds for TMEM238 Gene

No Compound Related Data Available

Transcripts for TMEM238 Gene

mRNA/cDNA for TMEM238 Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(22) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TMEM238 Gene

Transmembrane protein 238:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TMEM238

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM238 Gene

No ASD Table

Relevant External Links for TMEM238 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TMEM238 Gene

mRNA expression in normal human tissues for TMEM238 Gene

mRNA differential expression in normal tissues according to GTEx for TMEM238 Gene

This gene is overexpressed in Colon - Transverse (x6.7) and Pancreas (x5.0).

Protein differential expression in normal tissues from HIPED for TMEM238 Gene

This gene is overexpressed in Lung (58.2) and Fetal gut (10.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for TMEM238 Gene

SOURCE GeneReport for Unigene cluster for TMEM238 Gene Hs.534672

genes like me logo Genes that share expression patterns with TMEM238: view

Protein tissue co-expression partners for TMEM238 Gene

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for TMEM238 Gene

Orthologs for TMEM238 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TMEM238 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia TMEM238 35
  • 89.96 (n)
  • 86.75 (a)
(Canis familiaris)
Mammalia TMEM238 35
  • 92.07 (n)
  • 91.46 (a)
(Mus musculus)
Mammalia Tmem238 35
  • 86.55 (n)
  • 85.23 (a)
Tmem238 16
Tmem238 36
  • 85 (a)
(Pan troglodytes)
Mammalia TMEM238 35
  • 98.86 (n)
  • 97.73 (a)
TMEM238 36
  • 98 (a)
(Rattus norvegicus)
Mammalia Tmem238 35
  • 84.95 (n)
  • 81.71 (a)
(Monodelphis domestica)
Mammalia TMEM238 36
  • 13 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia tmem238 35
  • 61.4 (n)
  • 64.21 (a)
(Danio rerio)
Actinopterygii tmem238 36
  • 44 (a)
Species with no ortholog for TMEM238:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TMEM238 Gene

Gene Tree for TMEM238 (if available)
Gene Tree for TMEM238 (if available)

Paralogs for TMEM238 Gene

No data available for Paralogs for TMEM238 Gene

Variants for TMEM238 Gene

Sequence variations from dbSNP and Humsavar for TMEM238 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs2305786 -- 55,379,047(+) CCCCC(A/G)CCCCC downstream-variant-500B
rs2305787 -- 55,379,439(+) GCCTG(A/C/G)GGGGG intron-variant
rs2305788 -- 55,379,466(+) CATCC(A/G)CCTGC intron-variant
rs7251089 -- 55,381,263(+) aaaat(A/C)caaaa intron-variant
rs10424959 -- 55,382,845(+) CTCCT(A/C/T)CTTTT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TMEM238 Gene

Variant ID Type Subtype PubMed ID
dgv4016n71 CNV Loss 21882294
nsv912457 CNV Loss 21882294
nsv912460 CNV Loss 21882294
nsv912461 CNV Loss 21882294
nsv470162 CNV Loss 18288195
dgv4017n71 CNV Loss 21882294
nsv912463 CNV Loss 21882294
nsv516199 CNV Loss 19592680
dgv4020n71 CNV Loss 21882294
nsv912473 CNV Loss 21882294

Variation tolerance for TMEM238 Gene

Gene Damage Index Score: 1.02; 21.01% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TMEM238 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TMEM238 Gene

Disorders for TMEM238 Gene

Relevant External Links for TMEM238

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with TMEM238: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TMEM238 Gene

Publications for TMEM238 Gene

  1. A quantitative atlas of mitotic phosphorylation. (PMID: 18669648) Dephoure N. … Gygi S.P. (Proc. Natl. Acad. Sci. U.S.A. 2008) 67
  2. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 67
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 67

Products for TMEM238 Gene

Sources for TMEM238 Gene

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