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Aliases for TMEM233 Gene

Aliases for TMEM233 Gene

  • Transmembrane Protein 233 2 3
  • Interferon-Induced Transmembrane Domain-Containing Protein D2 3 4
  • Interferon Induced Transmembrane Protein Domain Containing 2 2 3
  • Dispanin Subfamily B Member 2 3 4
  • IFITMD2 3 4
  • DSPB2 3 4

External Ids for TMEM233 Gene

Previous GeneCards Identifiers for TMEM233 Gene

  • GC12P118516
  • GC12P120031
  • GC12P117039

Summaries for TMEM233 Gene

GeneCards Summary for TMEM233 Gene

TMEM233 (Transmembrane Protein 233) is a Protein Coding gene. An important paralog of this gene is TUSC5.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM233 Gene

Genomics for TMEM233 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for TMEM233 Gene

Start:
119,593,459 bp from pter
End:
119,643,066 bp from pter
Size:
49,608 bases
Orientation:
Plus strand

Genomic View for TMEM233 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMEM233 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM233 Gene

No data available for Regulatory Elements for TMEM233 Gene

Proteins for TMEM233 Gene

  • Protein details for TMEM233 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    B4DJY2-TM233_HUMAN
    Recommended name:
    Transmembrane protein 233
    Protein Accession:
    B4DJY2
    Secondary Accessions:

    Protein attributes for TMEM233 Gene

    Size:
    109 amino acids
    Molecular mass:
    12074 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMEM233 Gene

Proteomics data for TMEM233 Gene at MOPED

Post-translational modifications for TMEM233 Gene

  • Ubiquitination at Lys11
  • Modification sites at PhosphoSitePlus

Other Protein References for TMEM233 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TMEM233 Gene

Domains for TMEM233 Gene

Protein Domains for TMEM233 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TMEM233 Gene

Graphical View of Domain Structure for InterPro Entry

B4DJY2

UniProtKB/Swiss-Prot:

TM233_HUMAN :
  • B4DJY2
Family:
  • Belongs to the CD225/Dispanin family.
genes like me logo Genes that share domains with TMEM233: view

No data available for Gene Families for TMEM233 Gene

Function for TMEM233 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TMEM233 Gene

Localization for TMEM233 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM233 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TMEM233 Gene COMPARTMENTS Subcellular localization image for TMEM233 gene
Compartment Confidence
plasma membrane 3

Gene Ontology (GO) - Cellular Components for TMEM233 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM233: view

Pathways for TMEM233 Gene

SuperPathways for TMEM233 Gene

No Data Available

Interacting Proteins for TMEM233 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000403130%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: ENSP00000403130 for TMEM233 Gene via STRING

Symbol External ID(s) Details
UBC

Gene Ontology (GO) - Biological Process for TMEM233 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0009607 response to biotic stimulus IEA --
genes like me logo Genes that share ontologies with TMEM233: view

No data available for Pathways by source for TMEM233 Gene

Transcripts for TMEM233 Gene

mRNA/cDNA for TMEM233 Gene

Unigene Clusters for TMEM233 Gene

Transmembrane protein 233:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TMEM233

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for TMEM233
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM233 Gene

No ASD Table

Relevant External Links for TMEM233 Gene

GeneLoc Exon Structure for
TMEM233
ECgene alternative splicing isoforms for
TMEM233

Expression for TMEM233 Gene

mRNA expression in normal human tissues for TMEM233 Gene

mRNA differential expression in normal tissues according to GTEx for TMEM233 Gene

This gene is overexpressed in Muscle - Skeletal (37.6).

SOURCE GeneReport for Unigene cluster for TMEM233 Gene Hs.530965

genes like me logo Genes that share expressions with TMEM233: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein expression and mRNA Expression by UniProt/SwissProt for TMEM233 Gene

Orthologs for TMEM233 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TMEM233 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TMEM233 35
  • 99.69 (n)
  • 100 (a)
TMEM233 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia TMEM233 35
  • 87.42 (n)
  • 83.96 (a)
dog
(Canis familiaris)
Mammalia TMEM233 35
  • 92.05 (n)
  • 93.58 (a)
TMEM233 36
  • 93 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tmem233 35
  • 83.64 (n)
  • 87.04 (a)
Tmem233 16
Tmem233 36
  • 55 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia TMEM233 36
  • 73 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 33 (a)
ManyToMany
chicken
(Gallus gallus)
Aves TMEM233 35
  • 71.87 (n)
  • 67.89 (a)
lizard
(Anolis carolinensis)
Reptilia TMEM233 36
  • 44 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia tmem233 35
  • 66.98 (n)
  • 67.29 (a)
zebrafish
(Danio rerio)
Actinopterygii BX005328.1 36
  • 47 (a)
OneToOne
LOC101885033 35
  • 57.93 (n)
  • 55.34 (a)
Species with no ortholog for TMEM233:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TMEM233 Gene

ENSEMBL:
Gene Tree for TMEM233 (if available)
TreeFam:
Gene Tree for TMEM233 (if available)

Paralogs for TMEM233 Gene

Paralogs for TMEM233 Gene

Selected SIMAP similar genes for TMEM233 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with TMEM233: view

Variants for TMEM233 Gene

Sequence variations from dbSNP and Humsavar for TMEM233 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type MAF
rs739421 -- 119,604,585(+) TCCCC(C/G)TTTCT intron-variant
rs739422 -- 119,604,701(+) TGCAA(C/T)CATGG intron-variant
rs739423 -- 119,605,169(-) AGAAA(C/T)ACTAA intron-variant
rs746297 -- 119,604,996(+) TCACT(A/C)TCTTT intron-variant
rs929183 -- 119,597,142(+) GTGCA(A/G)TAGAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TMEM233 Gene

Variant ID Type Subtype PubMed ID
nsv832529 CNV Loss 17160897

Relevant External Links for TMEM233 Gene

HapMap Linkage Disequilibrium report
TMEM233

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TMEM233 Gene

Disorders for TMEM233 Gene

Relevant External Links for TMEM233

Genetic Association Database (GAD)
TMEM233
Human Genome Epidemiology (HuGE) Navigator
TMEM233
genes like me logo Genes that share disorders with TMEM233: view

No data available for UniProtKB/Swiss-Prot for TMEM233 Gene

Publications for TMEM233 Gene

  1. The dispanins: a novel gene family of ancient origin that contains 14 human members. (PMID: 22363774) Sallman Almen M. … Schioth H.B. (PLoS ONE 2012) 3 4
  2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 48
  3. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PMID: 21890473) Wagner S.A. … Choudhary C. (Mol. Cell Proteomics 2011) 3
  4. Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with BehAset's disease. (PMID: 20622878) Remmers E.F. … GA1l A. (Nat. Genet. 2010) 48
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4

Products for TMEM233 Gene

Sources for TMEM233 Gene

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