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Aliases for TMEM233 Gene

Aliases for TMEM233 Gene

  • Transmembrane Protein 233 2 3
  • Interferon-Induced Transmembrane Domain-Containing Protein D2 3 4
  • Interferon Induced Transmembrane Protein Domain Containing 2 2 3
  • Dispanin Subfamily B Member 2 3 4
  • IFITMD2 3 4
  • DSPB2 3 4

External Ids for TMEM233 Gene

Previous GeneCards Identifiers for TMEM233 Gene

  • GC12P118516
  • GC12P120031
  • GC12P117039

Summaries for TMEM233 Gene

GeneCards Summary for TMEM233 Gene

TMEM233 (Transmembrane Protein 233) is a Protein Coding gene. An important paralog of this gene is TUSC5.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM233 Gene

Genomics for TMEM233 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for TMEM233 Gene

119,592,636 bp from pter
119,654,442 bp from pter
61,807 bases
Plus strand

Genomic View for TMEM233 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for TMEM233 Gene

No data available for Regulatory Elements for TMEM233 Gene

Proteins for TMEM233 Gene

  • Protein details for TMEM233 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Transmembrane protein 233
    Protein Accession:

    Protein attributes for TMEM233 Gene

    109 amino acids
    Molecular mass:
    12074 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMEM233 Gene

Proteomics data for TMEM233 Gene at MOPED

Post-translational modifications for TMEM233 Gene

  • Ubiquitination at Lys 11
  • Modification sites at PhosphoSitePlus

Other Protein References for TMEM233 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TMEM233 Gene

Domains & Families for TMEM233 Gene

Protein Domains for TMEM233 Gene


Suggested Antigen Peptide Sequences for TMEM233 Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the CD225/Dispanin family.
  • Belongs to the CD225/Dispanin family.
genes like me logo Genes that share domains with TMEM233: view

No data available for Gene Families for TMEM233 Gene

Function for TMEM233 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targets and HOMER Transcription for TMEM233 Gene

Localization for TMEM233 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM233 Gene

Membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for TMEM233 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM233: view

No data available for Subcellular locations from COMPARTMENTS for TMEM233 Gene

Pathways & Interactions for TMEM233 Gene

SuperPathways for TMEM233 Gene

No Data Available

Interacting Proteins for TMEM233 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000403130 for TMEM233 Gene via STRING

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for TMEM233 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0009607 response to biotic stimulus IEA --
genes like me logo Genes that share ontologies with TMEM233: view

No data available for Pathways by source and SIGNOR curated interactions for TMEM233 Gene

Drugs & Compounds for TMEM233 Gene

No Compound Related Data Available

Transcripts for TMEM233 Gene

mRNA/cDNA for TMEM233 Gene

Unigene Clusters for TMEM233 Gene

Transmembrane protein 233:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TMEM233

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM233 Gene

No ASD Table

Relevant External Links for TMEM233 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TMEM233 Gene

mRNA expression in normal human tissues for TMEM233 Gene

mRNA differential expression in normal tissues according to GTEx for TMEM233 Gene

This gene is overexpressed in Muscle - Skeletal (x37.6).

SOURCE GeneReport for Unigene cluster for TMEM233 Gene Hs.530965

genes like me logo Genes that share expression patterns with TMEM233: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for TMEM233 Gene

Orthologs for TMEM233 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TMEM233 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia TMEM233 35
  • 87.42 (n)
  • 83.96 (a)
(Canis familiaris)
Mammalia TMEM233 35
  • 92.05 (n)
  • 93.58 (a)
TMEM233 36
  • 93 (a)
(Mus musculus)
Mammalia Tmem233 35
  • 83.64 (n)
  • 87.04 (a)
Tmem233 16
Tmem233 36
  • 55 (a)
(Pan troglodytes)
Mammalia TMEM233 35
  • 99.69 (n)
  • 100 (a)
TMEM233 36
  • 100 (a)
(Monodelphis domestica)
Mammalia TMEM233 36
  • 73 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 33 (a)
(Gallus gallus)
Aves TMEM233 35
  • 71.87 (n)
  • 67.89 (a)
(Anolis carolinensis)
Reptilia TMEM233 36
  • 44 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia tmem233 35
  • 66.98 (n)
  • 67.29 (a)
(Danio rerio)
Actinopterygii LOC101885033 35
  • 57.93 (n)
  • 55.34 (a)
BX005328.1 36
  • 47 (a)
Species with no ortholog for TMEM233:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TMEM233 Gene

Gene Tree for TMEM233 (if available)
Gene Tree for TMEM233 (if available)

Paralogs for TMEM233 Gene

Paralogs for TMEM233 Gene

(1) SIMAP similar genes for TMEM233 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with TMEM233: view

Variants for TMEM233 Gene

Structural Variations from Database of Genomic Variants (DGV) for TMEM233 Gene

Variant ID Type Subtype PubMed ID
nsv832529 CNV Loss 17160897

Variation tolerance for TMEM233 Gene

Gene Damage Index Score: 0.61; 13.02% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TMEM233 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for TMEM233 Gene

Disorders for TMEM233 Gene

Relevant External Links for TMEM233

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with TMEM233: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TMEM233 Gene

Publications for TMEM233 Gene

  1. The dispanins: a novel gene family of ancient origin that contains 14 human members. (PMID: 22363774) Sallman Almen M. … Schioth H.B. (PLoS ONE 2012) 67
  2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 67
  3. Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with BehAset's disease. (PMID: 20622878) Remmers E.F. … GA1l A. (Nat. Genet. 2010) 67
  4. The finished DNA sequence of human chromosome 12. (PMID: 16541075) Scherer S.E. … Gibbs R.A. (Nature 2006) 67
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 67

Products for TMEM233 Gene

Sources for TMEM233 Gene

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