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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TMEM231 Gene

protein-coding   GIFtS: 43
GCID: GC16M075572

Transmembrane Protein 231

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Transmembrane Protein 2311 2
ALYE8702
JBTS202
MKS112
PRO18862

External Ids:    HGNC: 372341   Entrez Gene: 795832   Ensembl: ENSG000002050847   OMIM: 6149495   UniProtKB: Q9H6L23   

Export aliases for TMEM231 gene to outside databases

Previous GC identifers: GC16M074130 GC16M061325


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for TMEM231 Gene:
This gene encodes a transmembrane protein, which is a component of the B9 complex involved in the formation of the
diffusion barrier between the cilia and plasma membrane. Mutations in this gene cause Joubert syndrome (JBTS).
Multiple alternatively spliced transcript variants have been found for this gene. (provided by RefSeq, Jan 2013)

GeneCards Summary for TMEM231 Gene: 
TMEM231 (transmembrane protein 231) is a protein-coding gene. Diseases associated with TMEM231 include doid:4019, and joubert syndrome 20. An important paralog of this gene is ENSG00000260092.

UniProtKB/Swiss-Prot: TM231_HUMAN, Q9H6L2
Function: Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of
primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and
plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000016.9  NC_018927.2  NT_010498.15  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for TMEM231
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for TMEM231

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TMEM231


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16q23.1   Ensembl cytogenetic band:  16q23.1   HGNC cytogenetic band: 16q23.1

TMEM231 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMEM231 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16M075572:  view genomic region     (about GC identifiers)

Start:
75,572,015 bp from pter      End:
75,590,184 bp from pter
Size:
18,170 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TM231_HUMAN, Q9H6L2 (See protein sequence)
Recommended Name: Transmembrane protein 231  
Size: 316 amino acids; 36059 Da
Subunit: Part of the tectonic-like complex (also named B9 complex) (By similarity)
Subcellular location: Cell projection, cilium membrane; Multi-pass membrane protein (By similarity).
Note=Localizes to the transition zone of primary cilia; SEPT2 is required for localization to the transition zone
(By similarity)
Secondary accessions: A0JLU1 A6NDZ6 B3KU85 G5E9E3 Q6P450 Q6UWW5
Alternative splicing: 3 isoforms:  Q9H6L2-1   Q9H6L2-2   Q9H6L2-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TMEM231: NX_Q9H6L2

Explore proteomics data for TMEM231 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9H6L2

  • TMEM231 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    TMEM231 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001070884.2  NP_001070886.1  

    ENSEMBL proteins: 
     ENSP00000258173   ENSP00000454582   ENSP00000457254   ENSP00000455520   ENSP00000381184  

    Human Recombinant Protein Products for TMEM231: 
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    Novus Biologicals TMEM231 Protein
    Novus Biologicals TMEM231 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TMEM231 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral to membrane IEA--
    GO:0035869ciliary transition zone ISS--
    GO:0036038TCTN-B9D complex ISS--
    GO:0060170cilium membrane ISS--

    TMEM231 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR019306 TMEM231

    Graphical View of Domain Structure for InterPro Entry Q9H6L2

    ProtoNet protein and cluster: Q9H6L2

    UniProtKB/Swiss-Prot: TM231_HUMAN, Q9H6L2
    Similarity: Belongs to the TMEM231 family


    TMEM231 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TM231_HUMAN, Q9H6L2
    Function: Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of
    primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and
    plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity)

    Phenotypes:
         6 MGI mutant phenotypes (inferred from 1 allele(MGI details for Tmem231):

     cardiovascular system  embryogenesis  limbs/digits/tail  mortality/aging  nervous system 
     vision/eye 

    TMEM231 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for TMEM231 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TMEM231 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TMEM231 

    miRNA
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    hsa-miR-875-3p hsa-miR-3133 hsa-miR-1262 hsa-miR-3916 hsa-miR-3125 hsa-miR-3692 hsa-miR-587 hsa-miR-593
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM231


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TMEM231

    STRING Interaction Network Preview (showing 5 interactants - click image to see 11)

    5/11 Interacting proteins for TMEM231 (ENSP000003811844) via UniProtKB, MINT, STRING, and/or I2D (see all 11)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    AHI1ENSP000003567744STRING: ENSP00000356774
    CEP290ENSP000003080214STRING: ENSP00000308021
    TCTN1ENSP000003807794STRING: ENSP00000380779
    TCTN2ENSP000003049414STRING: ENSP00000304941
    TMEM216ENSP000003819504STRING: ENSP00000381950
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007224smoothened signaling pathway ISS--
    GO:0042384cilium assembly ISS--

    TMEM231 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TMEM231 (TM231)

    Search CenterWatch for drugs/clinical trials and news about TMEM231 / TM231

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TMEM231 gene (2 alternative transcripts): 
    NM_001077416.2  NM_001077418.2  

    Unigene Cluster for TMEM231:

    Transmembrane protein 231
    Hs.156784  [show with all ESTs]
    Unigene Representative Sequence: NR_074083
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000258173(uc002fem.3) ENST00000562410(uc002fel.3) ENST00000568377
    ENST00000564318 ENST00000565067 ENST00000570006 ENST00000569294(uc010vne.1)
    ENST00000564576 ENST00000561809 ENST00000398114(uc002fek.3)
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TMEM231
    8/10 QIAGEN miScript miRNA Assays for microRNAs that regulate TMEM231 (see all 10):
    hsa-miR-875-3p hsa-miR-3133 hsa-miR-1262 hsa-miR-3916 hsa-miR-3125 hsa-miR-3692 hsa-miR-587 hsa-miR-593
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
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    Clone
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    Sirion Biotech Customized lentivirus for stable overexpression of TMEM231 
                         Customized lentivirus expression plasmids for stable overexpression of TMEM231 
    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMEM231
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMEM231

    Additional mRNA sequence: 

    AK025820.1 AK057689.1 AK096650.1 AK290483.1 AK298994.1 AK307263.1 AY358612.1 BC010609.1 
    BC016401.1 BC063677.1 NR_074082.1 NR_074083.1 

    18 DOTS entries:

    DT.114800  DT.70103156  DT.95165792  DT.100811816  DT.100676011  DT.120669767  DT.100811815  DT.120669782 
    DT.91752973  DT.95152131  DT.120669745  DT.120669754  DT.91752974  DT.91869752  DT.100702990  DT.307254 
    DT.40121075  DT.75153978 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TMEM231 expression in normal human tissues (normalized intensities)      TMEM231 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATGTTTTGTA
    TMEM231 Expression
    About this image


    TMEM231 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/3 selected tissues (see all 3) fully expand
     
     Epithelium (Respiratory System)    fully expand to see all 4 entries
             bronchial epithelia   
     
     Pancreas (Endocrine System)
             Posterior foregut-like cells ( A scalable, suspension protocol for derivation of...
     
     Nose (Sensory Organs)
             nasal epithelium   

    See TMEM231 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TMEM231

    SOURCE GeneReport for Unigene cluster: Hs.156784
        SABiosciences Custom PCR Arrays for TMEM231
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM231

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for TMEM231 gene from 5/11 species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tmem2311 , 5 transmembrane protein 2311, 5 85.08(n)1
    87.3(a)1
      8 (58.15 cM)5
    2347401  NM_001033321.11  NP_001028493.11 
     1119120185 
    chicken
    (Gallus gallus)
    Aves TMEM2311 transmembrane protein 231 71.84(n)
    73.93(a)
      425108  XM_422900.3  XP_422900.2 
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    63(a)
    1 → many
    GL343483.1(243792-249396)
    zebrafish
    (Danio rerio)
    Actinopterygii tmem2311 transmembrane protein 231 60.91(n)
    58.8(a)
      393358  NM_200387.1  NP_956681.1 
    worm
    (Caenorhabditis elegans)
    Secernentea T26A8.26
    Protein T26A8.2
    16(a)
    1 → many
    IV(8424278-8428512)


    ENSEMBL Gene Tree for TMEM231 (if available)
    TreeFam Gene Tree for TMEM231 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TMEM231 gene
    ENSG000002600922  

    TMEM231 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for TMEM231
    PGOHUM00000248936


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/576 SNPs in TMEM231 are shown (see all 576)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0690444
    Joubert syndrome 20 (JBTS20)4--see VAR_0690442 D N mis40--------
    rs612140821,2
    C--75580349(+) TTTTT-/T/TT  
            
    GAGCC
    4 -- int10--------
    rs582791821,2
    C--75584615(+) TTTTT-/T/    
       TG
    /TT
    GAGAT
    4 -- int10--------
    rs358068471,2
    C--75584616(+) TATTC-/T/TT  
            
    TTTTT
    4 -- int10--------
    rs609648401,2
    C--75585859(+) AAAAA-/AGAAAA 4 -- int11Minor allele frequency- A:0.50CSA 2
    rs1466568821,2
    --76583899(+) AATAGC/TTGGGA 3 -- ds50010--------
    rs1146987981,2
    C,F--76583914(+) AGGCAC/TGTGTC 3 -- ds50011Minor allele frequency- T:0.06WA 118
    rs1402434591,2
    --76583916(+) GCACGG/TGTCGC 3 -- ds50010--------
    rs1883447321,2
    --76583970(+) ACCATC/GTTGGC 3 -- ds50010--------
    rs1932032761,2
    C--76584012(+) TCACCC/TACCTC 3 -- ds50010--------

    HapMap Linkage Disequilibrium report for TMEM231 (75572015 - 75590184 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/18 variations for TMEM231 (see all 18):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2647265CNV Deletion19546169
    nsv436838CNV Insertion17901297
    dgv10e24CNV Loss17666407
    nsv906918CNV Loss21882294
    nsv525955CNV Loss19592680
    nsv906929CNV Loss21882294
    dgv352n27CNV Gain19166990
    dgv2914n71CNV Gain21882294
    nsv906926CNV Gain21882294
    nsv906927CNV Gain21882294


    Human Gene Mutation Database (HGMD): TMEM231
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing TMEM231
    DNA2.0 Custom Variant and Variant Library Synthesis for TMEM231

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 614949    OMIM disorders: --

    UniProtKB/Swiss-Prot: TM231_HUMAN, Q9H6L2
  • Joubert syndrome 20 (JBTS20) [MIM:614970]: A disorder presenting with cerebellar ataxia, oculomotor
    apraxia, hypotonia, neonatal breathing abnormalities and psychomotor delay. Neuroradiologically, it is
    characterized by cerebellar vermian hypoplasia/aplasia, thickened and reoriented superior cerebellar peduncles,
    and an abnormally large interpeduncular fossa, giving the appearance of a molar tooth on transaxial slices (molar
    tooth sign). Additional variable features include retinal dystrophy and renal disease. Note=The disease is caused
    by mutations affecting the gene represented in this entry

  • 9 diseases for TMEM231:    About MalaCards
    doid:4019    joubert syndrome 20    joubert syndrome    apraxia
    polydactyly    cerebellar ataxia    hypotonia    ataxia
    retinitis

    3 diseases from the University of Copenhagen DISEASES database for TMEM231:
    Polydactyly     Apraxia     DOID:4019

    TMEM231 for disorders           About GeneDecksing


    Export disorders for TMEM231 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TMEM231 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with TMEM231)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Mutations in TMEM231 cause Joubert syndrome in French Canadians. (PubMed id 23012439)1, 2 Srour M.... Michaud J.L. (2012)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
    4. A ciliopathy complex at the transition zone protects t he cilia as a privileged membrane domain. (PubMed id 22179047)1 Chih B....Peterson A.S. (2012)
    5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
    6. The sequence and analysis of duplication-rich human chromosome 16. (PubMed id 15616553)2 Martin J.... Pennacchio L.A. (2004)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    9. Joubert Syndrome (PubMed id 20301500)1 Parisi M. and Glass I. (1993)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 79583 HGNC: 37234 Ensembl:ENSG00000205084 euGenes: HUgn79583 ECgene: TMEM231
    H-InvDB: TMEM231

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TMEM231 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TMEM231 gene:
    Search GeneIP for patents involving TMEM231

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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