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Aliases for TMEM230 Gene

Aliases for TMEM230 Gene

  • Transmembrane Protein 230 2 3
  • C20orf30 3 4
  • UPF0414 Transmembrane Protein C20orf30 3
  • Chromosome 20 Open Reading Frame 30 2
  • DJ1116H23.2.1 3
  • HSPC274 3

External Ids for TMEM230 Gene

Previous Symbols for TMEM230 Gene

  • C20orf30

Summaries for TMEM230 Gene

GeneCards Summary for TMEM230 Gene

TMEM230 (Transmembrane Protein 230) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM230 Gene

Genomics for TMEM230 Gene

Genomic Location for TMEM230 Gene

Start:
5,068,232 bp from pter
End:
5,113,103 bp from pter
Size:
44,872 bases
Orientation:
Minus strand

Genomic View for TMEM230 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMEM230 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM230 Gene

No data available for Regulatory Elements for TMEM230 Gene

Proteins for TMEM230 Gene

  • Protein details for TMEM230 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96A57-TM230_HUMAN
    Recommended name:
    Transmembrane protein 230
    Protein Accession:
    Q96A57
    Secondary Accessions:
    • B2RDM8
    • D3DVZ9
    • Q0VGC8
    • Q5TDS5
    • Q96ES2
    • Q9P0A7

    Protein attributes for TMEM230 Gene

    Size:
    120 amino acids
    Molecular mass:
    13188 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for TMEM230 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TMEM230 Gene

Proteomics data for TMEM230 Gene at MOPED

Post-translational modifications for TMEM230 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for TMEM230 Gene

Domains for TMEM230 Gene

Protein Domains for TMEM230 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

TM230_HUMAN
Family:
  • Belongs to the TMEM134/TMEM230 family.:
    • Q96A57
genes like me logo Genes that share domains with TMEM230: view

No data available for Gene Families for TMEM230 Gene

Function for TMEM230 Gene

Phenotypes for TMEM230 Gene

GenomeRNAi human phenotypes for TMEM230:
genes like me logo Genes that share phenotypes with TMEM230: view

miRNA for TMEM230 Gene

miRTarBase miRNAs that target TMEM230

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targeting and HOMER Transcription for TMEM230 Gene

Localization for TMEM230 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM230 Gene

Membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for TMEM230 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM230: view

Pathways for TMEM230 Gene

SuperPathways for TMEM230 Gene

No Data Available

Interacting Proteins for TMEM230 Gene

STRING Interaction Network Preview (showing 4 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000341364%0d%0a9606.ENSP00000344818%0d%0a9606.ENSP00000378426%0d%0a9606.ENSP00000356298%0d%0a9606.ENSP00000401450%0d%0a
Selected Interacting proteins: Q96A57-TM230_HUMAN ENSP00000341364 for TMEM230 Gene via MINT STRING I2D

Gene Ontology (GO) - Biological Process for TMEM230 Gene

None

No data available for Pathways by source for TMEM230 Gene

Transcripts for TMEM230 Gene

Unigene Clusters for TMEM230 Gene

Transmembrane protein 230:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM230 Gene

ExUns: 1a · 1b · 1c · 1d · 1e · 1f · 1g · 1h ^ 2a · 2b · 2c · 2d · 2e · 2f · 2g · 2h ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b · 8c · 8d ^ 9a ·
SP1: - - - - - - - - - - -
SP2: - - - - - - - - - - -
SP3: - - - - -
SP4: - - - - - - - - - - -
SP5: - - - -
SP6: - - - - - - - - - - - -
SP7: - - - - - -
SP8: - - - - - - - - - - - -
SP9: - - - - - - - - - - - -
SP10: - - - - -
SP11: - - - -
SP12: - - - - -
SP13: - - - - - - -
SP14: - - - -
SP15: - - - - - - - - - - - - -
SP16: - - - - - - -
SP17: - - - - - - - - - - - - - - - -
SP18: - - - - - - - - - - - - - - -
SP19: - - -
SP20: - - - - - - -
SP21: - - - - - - - - -
SP22: - - - - - - - -
SP23: - - - - - - -

ExUns: 9b · 9c · 9d · 9e · 9f · 9g · 9h · 9i · 9j · 9k · 9l · 9m · 9n · 9o · 9p
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:
SP13:
SP14:
SP15:
SP16:
SP17:
SP18:
SP19:
SP20:
SP21:
SP22:
SP23:

Relevant External Links for TMEM230 Gene

GeneLoc Exon Structure for
TMEM230
ECgene alternative splicing isoforms for
TMEM230

Expression for TMEM230 Gene

mRNA expression in normal human tissues for TMEM230 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for TMEM230 Gene

SOURCE GeneReport for Unigene cluster for TMEM230 Gene Hs.472024

genes like me logo Genes that share expressions with TMEM230: view

Orthologs for TMEM230 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TMEM230 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TMEM230 36
  • 98.41 (n)
  • 98.41 (a)
TMEM230 37
  • 96 (a)
OneToOne
cow
(Bos Taurus)
Mammalia TMEM230 36
  • 92.5 (n)
  • 98.33 (a)
TMEM230 37
  • 56 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TMEM230 36
  • 92.5 (n)
  • 98.33 (a)
TMEM230 37
  • 98 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tmem230 36
  • 91.11 (n)
  • 96.67 (a)
Tmem230 16
Tmem230 37
  • 97 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia TMEM230 37
  • 89 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Tmem230 36
  • 91.39 (n)
  • 98.33 (a)
chicken
(Gallus gallus)
Aves C22H20ORF30 36
  • 78.89 (n)
  • 90 (a)
TMEM230 37
  • 90 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.16046 36
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.9040 36
tmem230 36
  • 76.11 (n)
  • 87.5 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.3506 36
zebrafish
(Danio rerio)
Actinopterygii TMEM230 (1 of 2) 37
  • 76 (a)
OneToMany
TMEM230 (2 of 2) 37
  • 74 (a)
OneToMany
zgc:101123 36
  • 70.28 (n)
  • 75.83 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 48 (a)
OneToOne
Species with no ortholog for TMEM230:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TMEM230 Gene

ENSEMBL:
Gene Tree for TMEM230 (if available)
TreeFam:
Gene Tree for TMEM230 (if available)

Paralogs for TMEM230 Gene

Selected SIMAP similar genes for TMEM230 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with TMEM230: view

No data available for Paralogs for TMEM230 Gene

Variants for TMEM230 Gene

Sequence variations from dbSNP and Humsavar for TMEM230 Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type MAF
rs2715 -- 5,100,403(+) ataaa(A/C/T)tactt utr-variant-3-prime
rs2716 -- 5,100,359(+) GGTAG(A/G)GATAA utr-variant-3-prime
rs382857 -- 5,102,826(-) ttttt(C/G)ttttt intron-variant
rs1040783 -- 5,106,078(-) tgtgt(G/T)tgtCC intron-variant
rs1077045 -- 5,099,462(-) gaagt(A/G)agGGA downstream-variant-500B

Relevant External Links for TMEM230 Gene

HapMap Linkage Disequilibrium report
TMEM230

No data available for Structural Variations from Database of Genomic Variants (DGV) for TMEM230 Gene

Disorders for TMEM230 Gene

No disorders were found for TMEM230 Gene.

No data available for UniProtKB/Swiss-Prot for TMEM230 Gene

Publications for TMEM230 Gene

  1. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. The DNA sequence and comparative analysis of human chromosome 20. (PMID: 11780052) Deloukas P. … Rogers J. (Nature 2001) 3 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for TMEM230 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate TMEM230
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for TMEM230
    • Block miRNA regulation of TMEM230 using miScript Target Protectors

    Sources for TMEM230 Gene

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