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Aliases for TMEM229A Gene

Aliases for TMEM229A Gene

  • Transmembrane Protein 229A 2 3

External Ids for TMEM229A Gene

Previous GeneCards Identifiers for TMEM229A Gene

  • GC07M123463
  • GC07M123670
  • GC07M118035

Summaries for TMEM229A Gene

GeneCards Summary for TMEM229A Gene

TMEM229A (Transmembrane Protein 229A) is a Protein Coding gene. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity. An important paralog of this gene is TMEM229B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM229A Gene

Genomics for TMEM229A Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for TMEM229A Gene

124,030,916 bp from pter
124,033,469 bp from pter
2,554 bases
Minus strand

Genomic View for TMEM229A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMEM229A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM229A Gene

No data available for Regulatory Elements for TMEM229A Gene

Proteins for TMEM229A Gene

  • Protein details for TMEM229A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Transmembrane protein 229A
    Protein Accession:
    Secondary Accessions:
    • A4D0X6

    Protein attributes for TMEM229A Gene

    380 amino acids
    Molecular mass:
    42370 Da
    Quaternary structure:
    No Data Available
    • Sequence=EAL24328.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

neXtProt entry for TMEM229A Gene

Proteomics data for TMEM229A Gene at MOPED

Post-translational modifications for TMEM229A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TMEM229A Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TMEM229A Gene

Domains for TMEM229A Gene

Protein Domains for TMEM229A Gene


Suggested Antigen Peptide Sequences for TMEM229A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • B2RXF0
  • Belongs to the TMEM229 family.
genes like me logo Genes that share domains with TMEM229A: view

No data available for Gene Families for TMEM229A Gene

Function for TMEM229A Gene

Gene Ontology (GO) - Molecular Function for TMEM229A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003700 sequence-specific DNA binding transcription factor activity IEA --
genes like me logo Genes that share ontologies with TMEM229A: view

Phenotypes for TMEM229A Gene

GenomeRNAi human phenotypes for TMEM229A:
genes like me logo Genes that share phenotypes with TMEM229A: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TMEM229A Gene

Localization for TMEM229A Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM229A Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for TMEM229A Gene COMPARTMENTS Subcellular localization image for TMEM229A gene
Compartment Confidence
cytosol 2
extracellular 2
nucleus 2
peroxisome 2

Gene Ontology (GO) - Cellular Components for TMEM229A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
GO:0042025 host cell nucleus IEA --
genes like me logo Genes that share ontologies with TMEM229A: view

Pathways for TMEM229A Gene

SuperPathways for TMEM229A Gene

No Data Available

Interacting Proteins for TMEM229A Gene

Gene Ontology (GO) - Biological Process for TMEM229A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with TMEM229A: view

No data available for Pathways by source for TMEM229A Gene

Transcripts for TMEM229A Gene

mRNA/cDNA for TMEM229A Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TMEM229A Gene

Transmembrane protein 229A:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TMEM229A

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for TMEM229A
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM229A Gene

No ASD Table

Relevant External Links for TMEM229A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TMEM229A Gene

mRNA expression in normal human tissues for TMEM229A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for TMEM229A Gene

This gene is overexpressed in Brain - Substantia nigra (5.5), Brain - Spinal cord (cervical c-1) (5.3), Brain - Putamen (basal ganglia) (4.5), Brain - Hippocampus (4.1), and Brain - Caudate (basal ganglia) (4.1).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for TMEM229A Gene

SOURCE GeneReport for Unigene cluster for TMEM229A Gene Hs.450249

genes like me logo Genes that share expressions with TMEM229A: view

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for TMEM229A Gene

Orthologs for TMEM229A Gene

This gene was present in the common ancestor of chordates.

Orthologs for TMEM229A Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia TMEM229A 35
  • 99.47 (n)
  • 99.47 (a)
TMEM229A 36
  • 100 (a)
(Bos Taurus)
Mammalia TMEM229A 35
  • 88.4 (n)
  • 87.67 (a)
(Canis familiaris)
Mammalia TMEM229A 35
  • 84.61 (n)
  • 79.23 (a)
TMEM229A 36
  • 78 (a)
(Mus musculus)
Mammalia Tmem229a 35
  • 84.82 (n)
  • 82.38 (a)
Tmem229a 16
Tmem229a 36
  • 82 (a)
(Monodelphis domestica)
Mammalia TMEM229A 36
  • 59 (a)
(Rattus norvegicus)
Mammalia Tmem229a 35
  • 84.37 (n)
  • 82.11 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 36 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia tmem229a 35
  • 64.97 (n)
  • 59.37 (a)
(Danio rerio)
Actinopterygii LOC794725 35
  • 61.53 (n)
  • 56.27 (a)
Species with no ortholog for TMEM229A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TMEM229A Gene

Gene Tree for TMEM229A (if available)
Gene Tree for TMEM229A (if available)

Paralogs for TMEM229A Gene

Paralogs for TMEM229A Gene

Selected SIMAP similar genes for TMEM229A Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with TMEM229A: view

Variants for TMEM229A Gene

Sequence variations from dbSNP and Humsavar for TMEM229A Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type MAF
rs2158461 -- 124,030,538(-) TATCA(A/G)CGAGC downstream-variant-500B
rs6976786 -- 124,033,130(+) gcgcA(A/G)GGAGC utr-variant-5-prime
rs7785878 -- 124,031,617(+) GTAAA(C/T)GTTTT utr-variant-3-prime
rs7803499 -- 124,032,074(+) ATGGG(C/T)ACCCG synonymous-codon, reference
rs10243768 -- 124,031,482(+) AAAGA(C/T)CCCCC utr-variant-3-prime

Relevant External Links for TMEM229A Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for TMEM229A Gene

Disorders for TMEM229A Gene

Relevant External Links for TMEM229A

Genetic Association Database (GAD)
genes like me logo Genes that share disorders with TMEM229A: view

No data available for UniProtKB/Swiss-Prot for TMEM229A Gene

Publications for TMEM229A Gene

  1. Human chromosome 7: DNA sequence and biology. (PMID: 12690205) Scherer S.W. … Tsui L.-C. (Science 2003) 3 4
  2. Genome-wide association to body mass index and waist circumference: the Framingham Heart Study 100K project. (PMID: 17903300) Fox C.S. … Atwood L.D. (BMC Med. Genet. 2007) 48
  3. The DNA sequence of human chromosome 7. (PMID: 12853948) Hillier L.W. … Wilson R.K. (Nature 2003) 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  5. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo M.F. … Soares M.B. (Genome Res. 1996) 3

Products for TMEM229A Gene

Sources for TMEM229A Gene

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