Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TMEM222 Gene

protein-coding   GIFtS: 46
GCID: GC01P027648

Transmembrane Protein 222

(Previous name: chromosome 1 open reading frame 160)
(Previous symbol: C1orf160)
  Search for TMEM222
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3.2

Aliases
Transmembrane Protein 2221 2
C1orf1601 2 3
Chromosome 1 Open Reading Frame 1601

External Ids:    HGNC: 253631   Entrez Gene: 840652   Ensembl: ENSG000001865017   UniProtKB: Q9H0R33   
ORGUL members:    fRNAdb10:FR176500      
NONCODE14:n410441 n409540 n410442      
RNAdb15:EVF30338    

Export aliases for TMEM222 gene to outside databases

Previous GC identifers: GC01P027523 GC01P025904


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for TMEM222 Gene: 
TMEM222 (transmembrane protein 222) is a protein-coding gene, and is affiliated with the lncRNA class.

Gene Wiki entry for TMEM222 (C1orf160) Gene

fRNAdb sequence ontology for TMEM222:
nc_conserved_region - Non-coding region of sequence similarity by descent from a common ancestor.

View fRNAdb secondary structures for TMEM222

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.2  NT_004610.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TMEM222 gene promoter:
         SRF   USF1   p53   AML1a   SRF (504 AA)   POU3F2   RORalpha2   YY1   USF-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTMEM222 promoter sequence
   Search SABiosciences Chromatin IP Primers for TMEM222

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TMEM222


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p36.11   Ensembl cytogenetic band:  1p36.11   HGNC cytogenetic band: 1p36.11

TMEM222 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMEM222 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P027648:  view genomic region     (about GC identifiers)

Start:
27,648,636 bp from pter      End:
27,662,891 bp from pter
Size:
14,256 bases      Orientation:
plus strand
ORGUL member locations:
Legend (see complete legend)

ORGUL Member Locations for TMEM222

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TM222_HUMAN, Q9H0R3 (See protein sequence)
Recommended Name: Transmembrane protein 222  
Size: 208 amino acids; 23230 Da
Subcellular location: Membrane; Multi-pass membrane protein (Potential)
Sequence caution: Sequence=CAB66618.1; Type=Erroneous initiation;
Secondary accessions: D3DPL6 Q53HD8 Q5FVE9
Alternative splicing: 2 isoforms:  Q9H0R3-1   Q9H0R3-2   

Explore the universe of human proteins at neXtProt for TMEM222: NX_Q9H0R3

Explore proteomics data for TMEM222 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9H0R3

  • TMEM222 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    TMEM222 Protein Expression
    REFSEQ proteins: NP_115501.2  
    ENSEMBL proteins: 
     ENSP00000363189   ENSP00000419528   ENSP00000419878   ENSP00000417720   ENSP00000417853  
     ENSP00000417603   ENSP00000419292  

    Human Recombinant Protein Products for TMEM222: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for TMEM222
    OriGene Protein Over-expression Lysate for TMEM222
    OriGene MassSpec for TMEM222 
    OriGene Custom Protein Services for TMEM222
    GenScript Custom Purified and Recombinant Proteins Services for TMEM222
    Novus Biologicals TMEM222 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TMEM222 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral to membrane IEA--

    TMEM222 for ontologies           About GeneDecksing



    TMEM222 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for TMEM222
    GenScript Custom Superior Antibodies Services for TMEM222
    Novus Biologicals TMEM222 Antibodies
    Abcam antibodies for TMEM222
    Cloud-Clone Corp. Antibodies for TMEM222 
    ThermoFisher Antibodies for TMEM222
    LSBio Antibodies in human, mouse, rat for TMEM222 

    Assay Products for TMEM222: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for TMEM222
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for TMEM222
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for TMEM222 
    Cloud-Clone Corp. CLIAs for TMEM222


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR008496 DUF778

    Graphical View of Domain Structure for InterPro Entry Q9H0R3

    ProtoNet protein and cluster: Q9H0R3


    TMEM222 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for TMEM222 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for TMEM222

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TMEM222 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TMEM222 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TMEM222
    3 QIAGEN miScript miRNA Assays for microRNAs that regulate TMEM222:
    hsa-miR-875-3p hsa-miR-185* hsa-miR-1299
    SwitchGear 3'UTR luciferase reporter plasmidTMEM222 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for TMEM222
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TMEM222

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for TMEM222
    Sirion Biotech Customized adenovirus for overexpression of TMEM222

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for TMEM222 (see all 8)
    OriGene ORF clones in mouse, rat for TMEM222
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TMEM222 (NM_032125)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM222
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM222
    Sirion Biotech Customized lentivirus for stable overexpression of TMEM222 
                         Customized lentivirus expression plasmids for stable overexpression of TMEM222 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for TMEM222
    Search LifeMap BioReagents cell lines for TMEM222
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM222


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TMEM222

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5/11 Interacting proteins for TMEM222 (Q9H0R32, 3 ENSP000003631894) via UniProtKB, MINT, STRING, and/or I2D (see all 11)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ABHD16AO958702, 3, ENSP000003792824MINT-62701 MINT-62777 MINT-62603 I2D: score=5 STRING: ENSP00000379282
    ENSG00000236063O958702, 3, ENSP000004069654MINT-62701 MINT-62777 MINT-62603 I2D: score=5 STRING: ENSP00000406965
    ENSG00000206403O958702, 3MINT-62701 MINT-62777 MINT-62603 I2D: score=5 
    ENSG00000224552O958702, 3MINT-62701 MINT-62777 MINT-62603 I2D: score=5 
    ENSG00000230475O958702, 3MINT-62701 MINT-62777 MINT-62603 I2D: score=5 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TMEM222 (TM222)

    Search CenterWatch for drugs/clinical trials and news about TMEM222 / TM222

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    1 fRNAdb Secondary structure:


    REFSEQ mRNAs for TMEM222 gene: 
    NM_032125.2  

    Unigene Cluster for TMEM222:

    Transmembrane protein 222
    Hs.469171  [show with all ESTs]
    Unigene Representative Sequence: NR_037580
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000374076(uc001bns.4 uc001bnr.4) ENST00000464720(uc021ojt.1 uc001bnt.4)
    ENST00000466759 ENST00000486082 ENST00000464813 ENST00000478104 ENST00000498220
    ENST00000471456 ENST00000470223
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TMEM222
    3 QIAGEN miScript miRNA Assays for microRNAs that regulate TMEM222:
    hsa-miR-875-3p hsa-miR-185* hsa-miR-1299
    SwitchGear 3'UTR luciferase reporter plasmidTMEM222 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for TMEM222
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TMEM222
    Clone
    Products:
         
    OriGene clones in human, mouse for TMEM222 (see all 8)
    OriGene ORF clones in mouse, rat for TMEM222
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TMEM222 (NM_032125)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM222
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM222
    Sirion Biotech Customized lentivirus for stable overexpression of TMEM222 
                         Customized lentivirus expression plasmids for stable overexpression of TMEM222 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for TMEM222
    OriGene qSTAR qPCR primer pairs in human, mouse for TMEM222
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat TMEM222
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMEM222
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMEM222

    Additional mRNA sequence: 

    AF251699.1 AK222642.1 AK303821.1 AK307077.1 AK313110.1 AL136683.1 BC011579.1 BC090039.1 
    NR_037576.1 NR_037577.1 NR_037580.1 

    10 DOTS entries:

    DT.216024  DT.92436138  DT.100818591  DT.100818598  DT.95155604  DT.75118198  DT.100818596  DT.100818590 
    DT.405134  DT.95155606 

    24/300 AceView cDNA sequences (see all 300):

    BX394857 BM994918 BQ716961 AI692815 AI434829 BQ917627 CR612028 CB142970 
    AA648535 CR609586 BG747353 CR603097 BQ053033 BQ936791 CA426809 CR623375 
    BI859484 CR590629 BM550098 AI129072 CR603896 CF126155 CD633675 AA852345 

    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for TMEM222 (see all 7)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9a · 9b · 9c
    SP1:                                                  -     -                 -     -                     
    SP2:                                      -           -     -                 -                           
    SP3:                                      -           -     -                 -     -                     
    SP4:                                      -           -     -                                             
    SP5:                                                                          -     -                     


    ECgene alternative splicing isoforms for TMEM222

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TMEM222 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTGGTGATGG
    TMEM222 Expression
    About this image


    See TMEM222 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TMEM222

    SOURCE GeneReport for Unigene cluster: Hs.469171
        SABiosciences Custom PCR Arrays for TMEM222
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for TMEM222
    OriGene qSTAR qPCR primer pairs in human, mouse for TMEM222
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat TMEM222
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMEM222
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMEM222
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM222

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for TMEM222 gene from 9/17 species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tmem2221 , 5 transmembrane protein 2221, 5 88.14(n)1
    94.23(a)1
      4 (66.25 cM)5
    521741  NM_025667.31  NP_079943.21 
     1332660455 
    chicken
    (Gallus gallus)
    Aves TMEM2221 transmembrane protein 222 79.81(n)
    85.14(a)
      419582  XM_417729.3  XP_417729.2 
    lizard
    (Anolis carolinensis)
    Reptilia TMEM2226
    Uncharacterized protein
    84(a)
    1 ↔ 1
    GL343464.1(208488-215084)
    African clawed frog
    (Xenopus laevis)
    Amphibia BJ031123.12   -- 74.46(n)    BJ031123.1 
    zebrafish
    (Danio rerio)
    Actinopterygii tmem222b1 transmembrane protein 222b 70.53(n)
    73.78(a)
      558134  XM_002665517.2  XP_002665563.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG83721 CG8372 68.96(n)
    60.62(a)
      34121  NM_164800.1  NP_723362.1 
    worm
    (Caenorhabditis elegans)
    Secernentea H20J04.61 Protein H20J04.6 58.61(n)
    54.9(a)
      173766  NM_062361.3  NP_494762.2 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons RTH1 RTE1-like protein 49.12(n)
    42.11(a)
      824268  NM_001084799.1  NP_001078268.1 
    rice
    (Oryza sativa)
    Liliopsida Os03g07995001 hypothetical protein 54.32(n)
    45.06(a)
      4334443  NM_001058112.1  NP_001051577.1 


    ENSEMBL Gene Tree for TMEM222 (if available)
    TreeFam Gene Tree for TMEM222 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/264 SNPs in TMEM222 are shown (see all 264)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1397274161,2
    --27646808(+) TAGGGA/TGATGT 4 -- us2k10--------
    rs557644641,2
    C,F--27646986(+) TGCACA/TGGGGT 4 -- us2k10--------
    rs1443991271,2
    --27647042(+) ATCATA/TTTCTA 4 -- us2k10--------
    rs49705181,2
    C,F,A,H--27647082(+) ATCTCT/CGAGGT 4 -- us2k131Minor allele frequency- C:0.15EA NA NS CSA WA 3336
    rs1810894561,2
    --27647148(+) GCATAA/TGCTTT 4 -- us2k10--------
    rs1853769761,2
    --27647168(+) ACTGTC/GCCAGC 4 -- us2k10--------
    rs1906282791,2
    --27647472(+) CCCCAC/TCCCAG 4 -- us2k10--------
    rs1828567751,2
    --27647740(+) TTCCAC/TTCCTG 4 -- us2k10--------
    rs1505636301,2
    C--27647822(+) ATAAA-/ACACACA 4 -- us2k10--------
    rs1466376071,2
    --27647840(+) CACACA/GTGCGC 4 -- us2k10--------

    HapMap Linkage Disequilibrium report for TMEM222 (27648636 - 27662891 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for TMEM222:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv516766CNV Loss19592680
    dgv203n71CNV Loss21882294
    nsv526051CNV Gain19592680

    SABiosciences Cancer Mutation PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing TMEM222
    DNA2.0 Custom Variant and Variant Library Synthesis for TMEM222

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TMEM222 for disorders           About MalaCards
    OMIM information: 102620    

    TMEM222 for disorders           About GeneDecksing


    Export disorders for TMEM222 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TMEM222 gene, integrated from 9 sources (see all 13):
    (articles sorted by number of sources associating them with TMEM222)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2, 3 Wiemann S.... Poustka A. (2001)
    2. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    5. Global identification of modular cullin-RING ligase su bstrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (2011)
    6. A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070)1 Stelzl U.... Wanker E.E. (2005)
    7. Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PubMed id 15342556)1 Suzuki Y.... Sugano S. (2004)
    8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
    9. Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region. (PubMed id 14667819)1 Lehner B....Sanderson C.M. (2004)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 84065 HGNC: 25363 AceView: DKFZP564D0478 Ensembl:ENSG00000186501 euGenes: HUgn84065
    ECgene: TMEM222 H-InvDB: TMEM222

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TMEM222 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TMEM222 gene:
    Search GeneIP for patents involving TMEM222

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for TMEM222  
     OriGene qPCR primer pairs and template standards for TMEM222   OriGene Protein Over-expression Lysate for TMEM222  
     OriGene MassSpec something-or-other for TMEM222   OriGene clones in human, mouse for TMEM222  
     OriGene qSTAR qPCR primer pairs in human, mouse for TMEM222   OriGene Purified Protein for TMEM222  
     OriGene ORF clones in mouse, rat for TMEM222   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for TMEM222   OriGene Custom Protein Services for TMEM222  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TMEM222
     QIAGEN SeqTarget long-range PCR primers for resequencing TMEM222
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TMEM222
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TMEM222
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMEM222
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMEM222
     GenScript Custom Purified and Recombinant Proteins Services for TMEM222 GenScript cDNA clones with any tag delivered in your preferred vector for TMEM222
     GenScript Custom Assay Services for TMEM222 GenScript Custom Superior Antibodies Services for TMEM222
     GenScript Custom overexpressing Cell Line Services for TMEM222 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in TMEM222 promoter
     Search Chromatin IP Primers for TMEM222
     RT2 qPCR Primer Assay in human, mouse / rat TMEM222
     Search GNC Networks for TMEM222
     SABiosciences Custom PCR Arrays for TMEM222
     Search Tocris compounds for TMEM222 (TM222)
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     TMEM222 antibodies
     TMEM222 lysates
     Antibodies for TMEM222
     See all of Abcam's Antibodies, Kits and Proteins for TMEM222
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for TMEM222
     Antibodies for TMEM222
     ELISAs for TMEM222
     CLIAs for TMEM222
     Search LifeMap BioReagents cell lines for TMEM222
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM222
     SwitchGear 3'UTR luciferase reporter plasmids for TMEM222
     SwitchGear Promoter luciferase reporter plasmids for TMEM222
     ThermoFisher Antibodies for TMEM222
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM222
     inGenious Targeting Laboratory - Custom generated mouse model solutions for TMEM222
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for TMEM222
    Customized:
     lentivirus for stable overexpression of TMEM222
     lentivirus expression plasmids for stable overexpression of TMEM222
     adenovirus for overexpression of TMEM222
     LSBio Antibodies in human, mouse, rat for TMEM222
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      TMEM222 gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 106 solr: 1.4