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Aliases for TMEM215 Gene

Aliases for TMEM215 Gene

  • Transmembrane Protein 215 2 3 5

External Ids for TMEM215 Gene

Previous GeneCards Identifiers for TMEM215 Gene

  • GC09P032775
  • GC09P032741

Summaries for TMEM215 Gene

GeneCards Summary for TMEM215 Gene

TMEM215 (Transmembrane Protein 215) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM215 Gene

Genomics for TMEM215 Gene

Regulatory Elements for TMEM215 Gene

Genomic Location for TMEM215 Gene

Chromosome:
9
Start:
32,783,499 bp from pter
End:
32,789,201 bp from pter
Size:
5,703 bases
Orientation:
Plus strand

Genomic View for TMEM215 Gene

Genes around TMEM215 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TMEM215 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TMEM215 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM215 Gene

Proteins for TMEM215 Gene

  • Protein details for TMEM215 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q68D42-TM215_HUMAN
    Recommended name:
    Transmembrane protein 215
    Protein Accession:
    Q68D42
    Secondary Accessions:
    • Q6ZUU2

    Protein attributes for TMEM215 Gene

    Size:
    235 amino acids
    Molecular mass:
    25806 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMEM215 Gene

Proteomics data for TMEM215 Gene at MOPED

Post-translational modifications for TMEM215 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TMEM215 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TMEM215 Gene

Domains & Families for TMEM215 Gene

Protein Domains for TMEM215 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TMEM215 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TMEM215: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TMEM215 Gene

Function for TMEM215 Gene

genes like me logo Genes that share phenotypes with TMEM215: view

Animal Model Products

CRISPR Products

miRNA for TMEM215 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TMEM215 Gene

Localization for TMEM215 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM215 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TMEM215 Gene COMPARTMENTS Subcellular localization image for TMEM215 gene
Compartment Confidence
extracellular 2
plasma membrane 2
endoplasmic reticulum 1

No data available for Gene Ontology (GO) - Cellular Components for TMEM215 Gene

Pathways & Interactions for TMEM215 Gene

SuperPathways for TMEM215 Gene

No Data Available

Interacting Proteins for TMEM215 Gene

Gene Ontology (GO) - Biological Process for TMEM215 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TMEM215 Gene

Drugs & Compounds for TMEM215 Gene

No Compound Related Data Available

Transcripts for TMEM215 Gene

mRNA/cDNA for TMEM215 Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(6) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TMEM215 Gene

Transmembrane protein 215:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM215 Gene

No ASD Table

Relevant External Links for TMEM215 Gene

GeneLoc Exon Structure for
TMEM215
ECgene alternative splicing isoforms for
TMEM215

Expression for TMEM215 Gene

mRNA expression in normal human tissues for TMEM215 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for TMEM215 Gene

This gene is overexpressed in Testis (x17.8) and Nerve - Tibial (x17.8).

Protein differential expression in normal tissues from HIPED for TMEM215 Gene

This gene is overexpressed in Retina (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for TMEM215 Gene



SOURCE GeneReport for Unigene cluster for TMEM215 Gene Hs.522063

genes like me logo Genes that share expression patterns with TMEM215: view

Protein tissue co-expression partners for TMEM215 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for TMEM215 Gene

Orthologs for TMEM215 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TMEM215 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia TMEM215 35
  • 90.21 (n)
  • 92.34 (a)
TMEM215 36
  • 92 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TMEM215 35
  • 90.6 (n)
  • 93.16 (a)
TMEM215 36
  • 93 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tmem215 35
  • 87.94 (n)
  • 92.34 (a)
Tmem215 16
Tmem215 36
  • 92 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia TMEM215 35
  • 99.29 (n)
  • 99.57 (a)
TMEM215 36
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC690918 35
  • 86.81 (n)
  • 92.34 (a)
oppossum
(Monodelphis domestica)
Mammalia TMEM215 36
  • 79 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia TMEM215 36
  • 78 (a)
OneToOne
chicken
(Gallus gallus)
Aves TMEM215 35
  • 70.65 (n)
  • 65.93 (a)
TMEM215 36
  • 59 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia TMEM215 36
  • 55 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia tmem215 35
  • 60.72 (n)
  • 55.87 (a)
Species with no ortholog for TMEM215:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TMEM215 Gene

ENSEMBL:
Gene Tree for TMEM215 (if available)
TreeFam:
Gene Tree for TMEM215 (if available)

Paralogs for TMEM215 Gene

No data available for Paralogs for TMEM215 Gene

Variants for TMEM215 Gene

Sequence variations from dbSNP and Humsavar for TMEM215 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs167280 -- 32,785,890(+) CTTTG(C/G)AAGTG intron-variant, utr-variant-3-prime
rs214130 -- 32,787,722(-) CTCAT(A/G)TCTAT nc-transcript-variant, utr-variant-3-prime
rs300636 -- 32,788,679(+) CAGAA(A/T)TGTGT nc-transcript-variant, utr-variant-3-prime
rs300637 -- 32,786,655(+) AAAAT(G/T)CATGC intron-variant, nc-transcript-variant, utr-variant-3-prime
rs300638 -- 32,786,588(+) TCAGT(G/T)TAAAT intron-variant, nc-transcript-variant, utr-variant-3-prime

Variation tolerance for TMEM215 Gene

Residual Variation Intolerance Score: 64.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.83; 17.31% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TMEM215 Gene

HapMap Linkage Disequilibrium report
TMEM215

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for TMEM215 Gene

Disorders for TMEM215 Gene

Relevant External Links for TMEM215

Genetic Association Database (GAD)
TMEM215
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TMEM215

No disorders were found for TMEM215 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TMEM215 Gene

Publications for TMEM215 Gene

  1. A genome-wide association study of host genetic determinants of the antibody response to Anthrax Vaccine Adsorbed. (PMID: 22658931) Pajewski N.M. … Kaslow R.A. (Vaccine 2012) 3 67
  2. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo M.F. … Soares M.B. (Genome Res. 1996) 3

Products for TMEM215 Gene

Sources for TMEM215 Gene

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