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Aliases for TMEM213 Gene

Aliases for TMEM213 Gene

  • Transmembrane Protein 213 2 3

External Ids for TMEM213 Gene

Previous GeneCards Identifiers for TMEM213 Gene

  • GC07P138134
  • GC07P138482
  • GC07P132793

Summaries for TMEM213 Gene

GeneCards Summary for TMEM213 Gene

TMEM213 (Transmembrane Protein 213) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM213 Gene

Genomics for TMEM213 Gene

Regulatory Elements for TMEM213 Gene

Genomic Location for TMEM213 Gene

138,797,915 bp from pter
138,838,101 bp from pter
40,187 bases
Plus strand

Genomic View for TMEM213 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMEM213 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM213 Gene

Proteins for TMEM213 Gene

  • Protein details for TMEM213 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Transmembrane protein 213
    Protein Accession:
    Secondary Accessions:
    • A4D1R3
    • C9JH49
    • C9JX41
    • C9K0P0

    Protein attributes for TMEM213 Gene

    107 amino acids
    Molecular mass:
    11520 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAI31698.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Alternative splice isoforms for TMEM213 Gene


neXtProt entry for TMEM213 Gene

Proteomics data for TMEM213 Gene at MOPED

Post-translational modifications for TMEM213 Gene

No Post-translational modifications

Other Protein References for TMEM213 Gene

No data available for DME Specific Peptides for TMEM213 Gene

Domains & Families for TMEM213 Gene

Protein Domains for TMEM213 Gene


Suggested Antigen Peptide Sequences for TMEM213 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TMEM213: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TMEM213 Gene

Function for TMEM213 Gene

genes like me logo Genes that share phenotypes with TMEM213: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targets and HOMER Transcription for TMEM213 Gene

Localization for TMEM213 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM213 Gene

Membrane; Single-pass type I membrane protein.

Gene Ontology (GO) - Cellular Components for TMEM213 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM213: view

No data available for Subcellular locations from COMPARTMENTS for TMEM213 Gene

Pathways & Interactions for TMEM213 Gene

SuperPathways for TMEM213 Gene

No Data Available

Interacting Proteins for TMEM213 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
Selected Interacting proteins: ENSP00000390407 for TMEM213 Gene via STRING

Gene Ontology (GO) - Biological Process for TMEM213 Gene


No data available for Pathways by source and SIGNOR curated interactions for TMEM213 Gene

Drugs & Compounds for TMEM213 Gene

No Compound Related Data Available

Transcripts for TMEM213 Gene

mRNA/cDNA for TMEM213 Gene

Unigene Clusters for TMEM213 Gene

Transmembrane protein 213:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM213 Gene

No ASD Table

Relevant External Links for TMEM213 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TMEM213 Gene

mRNA expression in normal human tissues for TMEM213 Gene

mRNA differential expression in normal tissues according to GTEx for TMEM213 Gene

This gene is overexpressed in Kidney - Cortex (x37.7), Minor Salivary Gland (x4.2), Skin - Not Sun Exposed (Suprapubic) (x4.1), and Skin - Sun Exposed (Lower leg) (x4.1).

Protein differential expression in normal tissues from HIPED for TMEM213 Gene

This gene is overexpressed in Platelet (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for TMEM213 Gene

SOURCE GeneReport for Unigene cluster for TMEM213 Gene Hs.567729

genes like me logo Genes that share expression patterns with TMEM213: view

Protein tissue co-expression partners for TMEM213 Gene

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for TMEM213 Gene

Orthologs for TMEM213 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TMEM213 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia TMEM213 35
  • 84.11 (n)
  • 73.83 (a)
TMEM213 36
  • 61 (a)
(Canis familiaris)
Mammalia TMEM213 35
  • 82.24 (n)
  • 77.57 (a)
TMEM213 36
  • 65 (a)
(Mus musculus)
Mammalia Tmem213 35
  • 77.56 (n)
  • 73.08 (a)
Tmem213 16
Tmem213 36
  • 59 (a)
(Pan troglodytes)
Mammalia TMEM213 35
  • 99.07 (n)
  • 99.07 (a)
TMEM213 36
  • 67 (a)
(Rattus norvegicus)
Mammalia Tmem213 35
  • 77.99 (n)
  • 71.84 (a)
(Ornithorhynchus anatinus)
Mammalia TMEM213 36
  • 36 (a)
(Gallus gallus)
Aves TMEM213 35
  • 75.86 (n)
  • 79.31 (a)
TMEM213 36
  • 54 (a)
(Anolis carolinensis)
Reptilia TMEM213 36
  • 74 (a)
Species with no ortholog for TMEM213:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TMEM213 Gene

Gene Tree for TMEM213 (if available)
Gene Tree for TMEM213 (if available)

Paralogs for TMEM213 Gene

No data available for Paralogs for TMEM213 Gene

Variants for TMEM213 Gene

Sequence variations from dbSNP and Humsavar for TMEM213 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type MAF
rs896186 -- 138,803,463(-) AGCCC(A/G)GGACT utr-variant-3-prime
rs896187 -- 138,803,443(-) GACAG(A/G)AGCAG utr-variant-3-prime
rs896188 -- 138,803,438(-) AAGCA(A/G)ATAAC utr-variant-3-prime
rs896189 -- 138,803,371(-) AGTCT(C/T)ATAGT utr-variant-3-prime
rs2004723 -- 138,802,009(+) aaata(C/G)aaaaa intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TMEM213 Gene

Variant ID Type Subtype PubMed ID
esv2735212 CNV Deletion 23290073
nsv831154 CNV Gain 17160897
nsv516706 CNV Loss 19592680

Variation tolerance for TMEM213 Gene

Residual Variation Intolerance Score: 70.74% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.77; 16.28% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TMEM213 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TMEM213 Gene

Disorders for TMEM213 Gene

Relevant External Links for TMEM213

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with TMEM213: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TMEM213 Gene

Publications for TMEM213 Gene

  1. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 67
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 67
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 67
  5. Human chromosome 7: DNA sequence and biology. (PMID: 12690205) Scherer S.W. … Tsui L.-C. (Science 2003) 67

Products for TMEM213 Gene

Sources for TMEM213 Gene

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