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Aliases for TMEM212 Gene

Aliases for TMEM212 Gene

  • Transmembrane Protein 212 2 3 5

External Ids for TMEM212 Gene

Previous GeneCards Identifiers for TMEM212 Gene

  • GC03P173044
  • GC03P171561
  • GC03P168931

Summaries for TMEM212 Gene

GeneCards Summary for TMEM212 Gene

TMEM212 (Transmembrane Protein 212) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM212 Gene

Genomics for TMEM212 Gene

Genomic Location for TMEM212 Gene

171,843,349 bp from pter
171,938,715 bp from pter
95,367 bases
Plus strand

Genomic View for TMEM212 Gene

Genes around TMEM212 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TMEM212 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TMEM212 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM212 Gene

No data available for Regulatory Elements for TMEM212 Gene

Proteins for TMEM212 Gene

  • Protein details for TMEM212 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Transmembrane protein 212
    Protein Accession:

    Protein attributes for TMEM212 Gene

    194 amino acids
    Molecular mass:
    21425 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMEM212 Gene

Proteomics data for TMEM212 Gene at MOPED

Post-translational modifications for TMEM212 Gene

No Post-translational modifications

Other Protein References for TMEM212 Gene

No data available for DME Specific Peptides for TMEM212 Gene

Domains & Families for TMEM212 Gene

Protein Domains for TMEM212 Gene


Suggested Antigen Peptide Sequences for TMEM212 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TMEM212: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TMEM212 Gene

Function for TMEM212 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TMEM212 Gene

Localization for TMEM212 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM212 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for TMEM212 Gene COMPARTMENTS Subcellular localization image for TMEM212 gene
Compartment Confidence
plasma membrane 3

No data available for Gene Ontology (GO) - Cellular Components for TMEM212 Gene

Pathways & Interactions for TMEM212 Gene

SuperPathways for TMEM212 Gene

No Data Available

Interacting Proteins for TMEM212 Gene

Gene Ontology (GO) - Biological Process for TMEM212 Gene


No data available for Pathways by source and SIGNOR curated interactions for TMEM212 Gene

Drugs & Compounds for TMEM212 Gene

No Compound Related Data Available

Transcripts for TMEM212 Gene

mRNA/cDNA for TMEM212 Gene

(4) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(5) Selected AceView cDNA sequences:
(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TMEM212 Gene

Transmembrane protein 212:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM212 Gene

No ASD Table

Relevant External Links for TMEM212 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TMEM212 Gene

mRNA expression in normal human tissues for TMEM212 Gene

mRNA differential expression in normal tissues according to GTEx for TMEM212 Gene

This gene is overexpressed in Fallopian Tube (x23.9), Lung (x10.7), and Cervix - Endocervix (x7.2).

Protein differential expression in normal tissues from HIPED for TMEM212 Gene

This gene is overexpressed in Plasma (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for TMEM212 Gene

SOURCE GeneReport for Unigene cluster for TMEM212 Gene Hs.642307

genes like me logo Genes that share expression patterns with TMEM212: view

Protein tissue co-expression partners for TMEM212 Gene

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for TMEM212 Gene

Orthologs for TMEM212 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TMEM212 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia TMEM212 35
  • 84.88 (n)
  • 79.78 (a)
TMEM212 36
  • 77 (a)
(Canis familiaris)
Mammalia TMEM212 35
  • 84.52 (n)
  • 79.78 (a)
TMEM212 36
  • 76 (a)
(Mus musculus)
Mammalia Tmem212 35
  • 80.29 (n)
  • 79.03 (a)
Tmem212 16
Tmem212 36
  • 77 (a)
(Pan troglodytes)
Mammalia TMEM212 35
  • 99.31 (n)
  • 99.48 (a)
TMEM212 36
  • 97 (a)
(Rattus norvegicus)
Mammalia Tmem212 35
  • 79.93 (n)
  • 79.01 (a)
(Monodelphis domestica)
Mammalia TMEM212 36
  • 61 (a)
(Anolis carolinensis)
Reptilia TMEM212 36
  • 58 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia tmem212 35
  • 62.11 (n)
  • 53.01 (a)
Species with no ortholog for TMEM212:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TMEM212 Gene

Gene Tree for TMEM212 (if available)
Gene Tree for TMEM212 (if available)

Paralogs for TMEM212 Gene

No data available for Paralogs for TMEM212 Gene

Variants for TMEM212 Gene

Sequence variations from dbSNP and Humsavar for TMEM212 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs1828671 -- 171,863,783(-) AAGAC(A/C)TTACT intron-variant
rs3051292 -- 171,855,079(+) aacta(-/ATTA)gttaa intron-variant
rs3051294 -- 171,864,016(+) AGAGG(-/AAG)AATTG intron-variant
rs3843981 -- 171,867,659(-) TGGGC(A/G)GCAGA intron-variant
rs3850188 -- 171,842,037(+) AAAAC(A/C)ACAAT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for TMEM212 Gene

Variant ID Type Subtype PubMed ID
nsv7356 OTHER Inversion 18451855
nsv877985 CNV Gain 21882294
esv2672519 CNV Deletion 23128226

Variation tolerance for TMEM212 Gene

Gene Damage Index Score: 0.46; 10.09% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TMEM212 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TMEM212 Gene

Disorders for TMEM212 Gene

Relevant External Links for TMEM212

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for TMEM212 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TMEM212 Gene

Publications for TMEM212 Gene

  1. The DNA sequence, annotation and analysis of human chromosome 3. (PMID: 16641997) Muzny D.M. … Gibbs R.A. (Nature 2006) 3 4 67
  2. Genome-wide association of BMI in African Americans. (PMID: 21701570) Ng M.C. … Bowden D.W. (Obesity (Silver Spring) 2012) 3
  3. Genomic association analysis identifies multiple loci influencing antihypertensive response to an angiotensin II receptor blocker. (PMID: 22566498) Turner S.T. … Boerwinkle E. (Hypertension 2012) 3
  4. Genetic variants affecting the neural processing of human facial expressions: evidence using a genome-wide functional imaging approach. (PMID: 22828495) Brown A.A. … Andreassen O.A. (Transl Psychiatry 2012) 3
  5. A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder. (PMID: 20889312) Wang K.S. … Aragam N. (Schizophr. Res. 2010) 3

Products for TMEM212 Gene

Sources for TMEM212 Gene

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