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Aliases for TMEM209 Gene

Aliases for TMEM209 Gene

  • Transmembrane Protein 209 2 3
  • NET31 3

External Ids for TMEM209 Gene

Previous GeneCards Identifiers for TMEM209 Gene

  • GC07M129592
  • GC07M129804
  • GC07M124166

Summaries for TMEM209 Gene

GeneCards Summary for TMEM209 Gene

TMEM209 (Transmembrane Protein 209) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM209 Gene

Genomics for TMEM209 Gene

Regulatory Elements for TMEM209 Gene

Genomic Location for TMEM209 Gene

Start:
130,164,715 bp from pter
End:
130,207,770 bp from pter
Size:
43,056 bases
Orientation:
Minus strand

Genomic View for TMEM209 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMEM209 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM209 Gene

Proteins for TMEM209 Gene

  • Protein details for TMEM209 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96SK2-TM209_HUMAN
    Recommended name:
    Transmembrane protein 209
    Protein Accession:
    Q96SK2
    Secondary Accessions:
    • A4D1L1
    • Q49A50
    • Q6PF00
    • Q8NCH3
    • Q96SL6

    Protein attributes for TMEM209 Gene

    Size:
    561 amino acids
    Molecular mass:
    62922 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for TMEM209 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TMEM209 Gene

Proteomics data for TMEM209 Gene at MOPED

Post-translational modifications for TMEM209 Gene

  • Ubiquitination at Lys232, Lys257, Lys288, Lys312, and Lys338
  • Glycosylation at Asn57 and Asn274
  • Modification sites at PhosphoSitePlus

Other Protein References for TMEM209 Gene

No data available for DME Specific Peptides for TMEM209 Gene

Domains for TMEM209 Gene

Protein Domains for TMEM209 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TMEM209 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TMEM209: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TMEM209 Gene

Function for TMEM209 Gene

Animal Model Products

CRISPR Products

miRNA for TMEM209 Gene

miRTarBase miRNAs that target TMEM209

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for TMEM209 Gene

Localization for TMEM209 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM209 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TMEM209 Gene COMPARTMENTS Subcellular localization image for TMEM209 gene
Compartment Confidence
cytosol 2
nucleus 2
plasma membrane 2
cytoskeleton 1
golgi apparatus 1

Gene Ontology (GO) - Cellular Components for TMEM209 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM209: view

Pathways for TMEM209 Gene

SuperPathways for TMEM209 Gene

No Data Available

Interacting Proteins for TMEM209 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000380747%0d%0a9606.ENSP00000344818%0d%0a9606.ENSP00000385269%0d%0a
Selected Interacting proteins: ENSP00000380747 for TMEM209 Gene via STRING

Gene Ontology (GO) - Biological Process for TMEM209 Gene

None

No data available for Pathways by source for TMEM209 Gene

Transcripts for TMEM209 Gene

Unigene Clusters for TMEM209 Gene

Transmembrane protein 209:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TMEM209

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM209 Gene

ExUns: 1 ^ 2a · 2b ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b · 7c ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b ^ 13a · 13b ^ 14 ^ 15 ^ 16 ^ 17
SP1: - - - - -
SP2: - - - -
SP3: - - -
SP4: -
SP5: - - - - -
SP6:
SP7:

Relevant External Links for TMEM209 Gene

GeneLoc Exon Structure for
TMEM209
ECgene alternative splicing isoforms for
TMEM209

Expression for TMEM209 Gene

mRNA expression in normal human tissues for TMEM209 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for TMEM209 Gene

SOURCE GeneReport for Unigene cluster for TMEM209 Gene Hs.267245

genes like me logo Genes that share expressions with TMEM209: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for TMEM209 Gene

Orthologs for TMEM209 Gene

This gene was present in the common ancestor of animals.

Orthologs for TMEM209 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TMEM209 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia TMEM209 35
  • 92.14 (n)
  • 96.79 (a)
TMEM209 36
  • 95 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TMEM209 35
  • 93.46 (n)
  • 98.04 (a)
TMEM209 36
  • 98 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tmem209 35
  • 88.83 (n)
  • 95.19 (a)
Tmem209 16
Tmem209 36
  • 95 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia TMEM209 36
  • 89 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 87 (a)
OneToMany
-- 36
  • 85 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Tmem209 35
  • 88.18 (n)
  • 94.83 (a)
chicken
(Gallus gallus)
Aves TMEM209 35
  • 76.57 (n)
  • 86.23 (a)
TMEM209 36
  • 87 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia TMEM209 36
  • 83 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.4132 35
tmem209 35
  • 71.96 (n)
  • 75.71 (a)
zebrafish
(Danio rerio)
Actinopterygii tmem209 35
  • 67.71 (n)
  • 70.72 (a)
tmem209 36
  • 69 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG6479 36
  • 28 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea B0464.6 36
  • 19 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea CSA.960 36
  • 32 (a)
OneToOne
Species with no ortholog for TMEM209:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for TMEM209 Gene

ENSEMBL:
Gene Tree for TMEM209 (if available)
TreeFam:
Gene Tree for TMEM209 (if available)

Paralogs for TMEM209 Gene

Selected SIMAP similar genes for TMEM209 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with TMEM209: view

No data available for Paralogs for TMEM209 Gene

Variants for TMEM209 Gene

Sequence variations from dbSNP and Humsavar for TMEM209 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type MAF
rs931380 -- 130,197,351(+) catta(C/T)gctag intron-variant
rs1027071 -- 130,189,576(+) ATGCC(C/T)GCAAC intron-variant
rs1406110 -- 130,197,196(-) cgaat(C/G)gtgca intron-variant
rs1488008 -- 130,194,633(+) GATGG(C/T)TTCTT intron-variant
rs1852653 -- 130,198,336(+) TAggg(C/T)gaggt intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TMEM209 Gene

Variant ID Type Subtype PubMed ID
nsv5950 CNV Insertion 18451855
nsv508481 CNV Loss 20534489

Relevant External Links for TMEM209 Gene

HapMap Linkage Disequilibrium report
TMEM209

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TMEM209 Gene

Disorders for TMEM209 Gene

(1) University of Copenhagen DISEASES for TMEM209 Gene

genes like me logo Genes that share disorders with TMEM209: view

No data available for UniProtKB/Swiss-Prot for TMEM209 Gene

Publications for TMEM209 Gene

  1. Nuclear membrane proteins with potential disease links found by subtractive proteomics. (PMID: 12958361) Schirmer E.C. … Gerace L. (Science 2003) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Imprinting analysis of 10 genes and/or transcripts in a 1.5-Mb MEST- flanking region at human chromosome 7q32. (PMID: 14962666) Yamada T. … Kishino T. (Genomics 2004) 3
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3

Products for TMEM209 Gene

  • antibodies-online peptides for TMEM209
  • antibodies-online antibodies for TMEM209
  • antibodies-online kits for TMEM209

Sources for TMEM209 Gene

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