TMEM203 Gene
protein-coding GIFtS: 38
GCID: GC09M140098
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|
transmembrane protein 203
| |
Aliases
for TMEM203 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Transmembrane Protein 2031 2 | | HBEBP11 2 | | MGC143271 | | HBeAg-Binding Protein 12 |
Export aliases for TMEM203 gene to outside databasesPrevious GC identifers: GC09M139224 GC09M109558 |
Summaries
for TMEM203 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for TMEM203 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000009.11 NC_018920.1 NT_024000.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the TMEM203 gene promoter:
AhR RP58 SREBP-1c MyoD Arnt SREBP-1b Roaz SREBP-1a Pax-4a
Other transcription factors
Search SABiosciences Chromatin IP Primers for TMEM203
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TMEM203 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 9q34.3 Ensembl cytogenetic band: 9q34.3 HGNC cytogenetic band: 9q34.3TMEM203 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 9 GeneLoc Exon Structure GeneLoc location for GC09M140098: view genomic region
(about GC identifiers)
Start:
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140,098,534 bp from pter |
End:
|
140,100,090 bp from pter |
Size:
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1,557 bases |
Orientation:
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minus strand |
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Proteins
for TMEM203 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: TM203_HUMAN, Q969S6 (See
protein sequence)Recommended Name: Transmembrane protein 203 Size: 136 amino acids; 15760 Da
Subcellular location: Membrane; Multi-pass membrane protein (Potential)
Secondary accessions: Q6NW08Explore the universe of human proteins at neXtProt for TMEM203: NX_Q969S6
TMEM203 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_444273.1
ENSEMBL proteins: ENSP00000375053 ENSP00000446302
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016021 | integral to membrane |
IEA | -- |
TMEM203 for ontologies About GeneDecksing
TMEM203 Antibody Products:
Assay Products for TMEM203: |
Protein
Domains /
Families
for TMEM203 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
TMEM203 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q969S6ProtoNet protein and cluster: Q969S6 |
Function
for TMEM203 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TMEM203 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TMEM203
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: TMEM203 (NM_053045) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TMEM203 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM203 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM203 |
|
Pathways & Interactions
for TMEM203 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TMEM203
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
1 Interacting protein for TMEM203 (Q969S63 ENSP000003750534) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for TMEM203 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for TMEM203
Search CenterWatch for drugs/clinical trials and news about TMEM203 / TM203
|
Transcripts
for TMEM203 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for TMEM203 gene: NM_053045.1 Unigene Cluster for TMEM203: Transmembrane protein 203 Hs.231029 [show with all ESTs]Unigene Representative Sequence: BQ0677442 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000343666(uc004clv.3) ENST00000537254
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TMEM203 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TMEM203
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: TMEM203 (NM_053045) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TMEM203 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM203 |
Additional cDNA sequence: AF529372.1 BC009283.2 BC009461.1 BC067786.1 4 DOTS entries: DT.445107 DT.95142233 DT.100812642 DT.91881800 24/387 AceView cDNA sequences (see all 387): BU579839 BM671606 AA836018 AI918062 AA156490 AF529372 BU732301 BU073098 BM423462 BM931297 CA446274 BI820162 AA045314 BM875429 BQ010954 AI499773 BM468437 BQ427494 BQ012595 AI632688 AI148818 AW295777 BQ436419 BC071831
GeneLoc Exon Structure
|
Expression
for TMEM203 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| TMEM203 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGAACCTTTG
About this image
See TMEM203 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TMEM203
SOURCE GeneReport for Unigene cluster: Hs.231029
SABiosciences Custom PCR Arrays for TMEM203
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TMEM203
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TMEM203 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TMEM203 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TMEM203 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM203 |
Orthologs
for TMEM203 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for TMEM203 gene from 6/15 species (see all 15) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Tmem2031 , 5 |
transmembrane protein 2031, 5 |
88.24(n)1
97.79(a)1 |
|
2 (17.11 cM)5
2276151 NM_177344.31 NP_796318.21
252554395 |
chicken
(Gallus gallus) |
Aves |
TMEM2036 |
Uncharacterized protein |
86(a) |
1 ↔ 1 |
17(1341380-1341790) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.101052 |
Xenopus laevis transcribed sequence with moderate similarity more |
80.98(n) |
|
BI448552.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
wufb52h092 |
Transcribed sequence with moderate similarity to protein more |
76.86(n) |
|
57075806 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG339326 |
-- |
39(a) |
1 ↔ 1 |
X(19638464-19639780) |
worm
(Caenorhabditis elegans) |
Secernentea |
T07A9.126 |
Protein T07A9.12, isoform b |
24(a) |
1 ↔ 1 |
IV(414250-415679) |
ENSEMBL Gene Tree for TMEM203 (if available)
TreeFam Gene Tree for TMEM203 (if available) |
Paralogs
for TMEM203 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for TMEM203 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for TMEM203
1 CNV: 5415 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TMEM203 |
|
Disorders
/ Diseases
for TMEM203 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for TMEM203 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TMEM203 gene integrated from 9 sources:
(articles sorted by number of sources associating them with TMEM203) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- Defining the human deubiquitinating enzyme interactio n landscape. (PubMed id 19615732)1 Sowa M.E....Harper J.W. (2009)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)
|
External Searches for TMEM203 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing TMEM203 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TMEM203 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing TMEM203 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for TMEM203 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for TMEM203 gene:
Search GeneIP for patents involving TMEM203
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for TMEM203 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for TMEM203 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TMEM203 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TMEM203 | | | OriGene Protein Over-expression Lysate for TMEM203 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for TMEM203 | | OriGene 3'-UTR Clone for TMEM203 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TMEM203 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TMEM203 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| |
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| |
 |  |  |  | |
| | | | Search Tocris compounds for TMEM203 |
| |  |  |  |  | | | | |
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 | | | TMEM203 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM203 |
|  |  |  | | | | Search ThermoFisher Antibodies for TMEM203 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM203 |
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