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Aliases for TMEM203 Gene

Aliases for TMEM203 Gene

  • Transmembrane Protein 203 2 3
  • HBeAg-Binding Protein 1 2 3
  • HBEBP1 3

External Ids for TMEM203 Gene

Summaries for TMEM203 Gene

GeneCards Summary for TMEM203 Gene

TMEM203 (Transmembrane Protein 203) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM203 Gene

Genomics for TMEM203 Gene

Genomic Location for TMEM203 Gene

Start:
137,204,082 bp from pter
End:
137,205,638 bp from pter
Size:
1,557 bases
Orientation:
Minus strand

Genomic View for TMEM203 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMEM203 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM203 Gene

Regulatory Elements for TMEM203 Gene

Proteins for TMEM203 Gene

  • Protein details for TMEM203 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q969S6-TM203_HUMAN
    Recommended name:
    Transmembrane protein 203
    Protein Accession:
    Q969S6
    Secondary Accessions:
    • Q6NW08

    Protein attributes for TMEM203 Gene

    Size:
    136 amino acids
    Molecular mass:
    15760 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMEM203 Gene

Proteomics data for TMEM203 Gene at MOPED

Post-translational modifications for TMEM203 Gene

No Post-translational modifications

Other Protein References for TMEM203 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TMEM203 Gene

Domains for TMEM203 Gene

Protein Domains for TMEM203 Gene

InterPro:
ProtoNet:
genes like me logo Genes that share domains with TMEM203: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TMEM203 Gene

Function for TMEM203 Gene

miRNA for TMEM203 Gene

miRTarBase miRNAs that target TMEM203

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for TMEM203 Gene

Localization for TMEM203 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM203 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TMEM203 Gene COMPARTMENTS Subcellular localization image for TMEM203 gene
Compartment Confidence
plasma membrane 3
endoplasmic reticulum 1
extracellular 1
golgi apparatus 1

Gene Ontology (GO) - Cellular Components for TMEM203 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM203: view

Pathways for TMEM203 Gene

SuperPathways for TMEM203 Gene

No Data Available

Interacting Proteins for TMEM203 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000375053%0d%0a9606.ENSP00000429931%0d%0a
Selected Interacting proteins: ENSP00000375053 Q969S6-TM203_HUMAN for TMEM203 Gene via STRING I2D

Gene Ontology (GO) - Biological Process for TMEM203 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0002230 positive regulation of defense response to virus by host IMP 22020285
GO:0098779 activation of mitophagy in response to mitochondrial depolarization IMP 22020285
genes like me logo Genes that share ontologies with TMEM203: view

No data available for Pathways by source for TMEM203 Gene

Transcripts for TMEM203 Gene

mRNA/cDNA for TMEM203 Gene

(1) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(387) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TMEM203 Gene

Transmembrane protein 203:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM203 Gene

No ASD Table

Relevant External Links for TMEM203 Gene

GeneLoc Exon Structure for
TMEM203
ECgene alternative splicing isoforms for
TMEM203

Expression for TMEM203 Gene

mRNA expression in normal human tissues for TMEM203 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for TMEM203 Gene

SOURCE GeneReport for Unigene cluster for TMEM203 Gene Hs.231029

genes like me logo Genes that share expressions with TMEM203: view

Orthologs for TMEM203 Gene

This gene was present in the common ancestor of animals.

Orthologs for TMEM203 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TMEM203 36
  • 97.3 (n)
  • 96.32 (a)
cow
(Bos Taurus)
Mammalia TMEM203 36
  • 91.67 (n)
  • 97.79 (a)
TMEM203 37
  • 98 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TMEM203 36
  • 91.18 (n)
  • 97.79 (a)
TMEM203 37
  • 98 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tmem203 36
  • 88.24 (n)
  • 97.79 (a)
Tmem203 16
Tmem203 37
  • 98 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia TMEM203 37
  • 69 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Tmem203 36
  • 88.24 (n)
  • 97.79 (a)
chicken
(Gallus gallus)
Aves TMEM203 37
  • 86 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.10105 36
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.14635 36
tmem203 36
  • 78.43 (n)
  • 82.35 (a)
zebrafish
(Danio rerio)
Actinopterygii tmem203 36
  • 72.79 (n)
  • 80.88 (a)
tmem203 37
  • 76 (a)
OneToOne
wufb52h09 36
fruit fly
(Drosophila melanogaster)
Insecta CG33932 37
  • 39 (a)
OneToOne
Species with no ortholog for TMEM203:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TMEM203 Gene

ENSEMBL:
Gene Tree for TMEM203 (if available)
TreeFam:
Gene Tree for TMEM203 (if available)

Paralogs for TMEM203 Gene

No data available for Paralogs for TMEM203 Gene

Variants for TMEM203 Gene

Sequence variations from dbSNP and Humsavar for TMEM203 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
rs528978087 -- 137,203,633(+) ACAGG(A/C)GTGAG downstream-variant-500B
rs548843200 -- 137,203,662(+) TTTTG(C/T)TTTTA downstream-variant-500B
rs563327534 -- 137,203,629(+) GATTA(C/G)AGGCG downstream-variant-500B
rs575280322 -- 137,203,618(+) CAAAG(C/T)GCTGG downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for TMEM203 Gene

Variant ID Type Subtype PubMed ID
nsv894387 CNV Gain 21882294
esv2422220 CNV Deletion 17116639
dgv8412n71 CNV Loss 21882294
dgv8416n71 CNV Loss 21882294
nsv524322 CNV Loss 19592680
nsv894469 CNV Loss 21882294
dgv8423n71 CNV Loss 21882294
nsv894502 CNV Loss 21882294
nsv894506 CNV Gain 21882294
dgv8428n71 CNV Loss 21882294
nsv894521 CNV Loss 21882294
dgv8437n71 CNV Gain 21882294
dgv8441n71 CNV Loss 21882294
dgv8442n71 CNV Loss 21882294
dgv8445n71 CNV Loss 21882294
dgv8446n71 CNV Loss 21882294
dgv8447n71 CNV Loss 21882294
dgv8450n71 CNV Loss 21882294
nsv894603 CNV Gain+Loss 21882294
dgv8451n71 CNV Loss 21882294
dgv8452n71 CNV Gain+Loss 21882294
dgv8453n71 CNV Gain 21882294
dgv8454n71 CNV Gain 21882294
dgv8455n71 CNV Gain+Loss 21882294
nsv894629 CNV Loss 21882294
dgv8456n71 CNV Loss 21882294
nsv894631 CNV Loss 21882294
dgv8457n71 CNV Gain 21882294
nsv894637 CNV Loss 21882294

Relevant External Links for TMEM203 Gene

HapMap Linkage Disequilibrium report
TMEM203

Disorders for TMEM203 Gene

No disorders were found for TMEM203 Gene.

No data available for UniProtKB/Swiss-Prot for TMEM203 Gene

Publications for TMEM203 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Defining the human deubiquitinating enzyme interaction landscape. (PMID: 19615732) Sowa M.E. … Harper J.W. (Cell 2009) 3
  3. Image-based genome-wide siRNA screen identifies selective autophagy factors. (PMID: 22020285) Orvedahl A. … Levine B. (Nature 2011) 3
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4

Products for TMEM203 Gene

Sources for TMEM203 Gene

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