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Aliases for TMEM202 Gene

Aliases for TMEM202 Gene

  • Transmembrane Protein 202 2 3 5

External Ids for TMEM202 Gene

Previous GeneCards Identifiers for TMEM202 Gene

  • GC15P070479
  • GC15P072690
  • GC15P049521

Summaries for TMEM202 Gene

GeneCards Summary for TMEM202 Gene

TMEM202 (Transmembrane Protein 202) is a Protein Coding gene.

Additional gene information for TMEM202 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM202 Gene

Genomics for TMEM202 Gene

GeneHancer (GH) Regulatory Elements for TMEM202 Gene

Promoters and enhancers for TMEM202 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH15I072398 Promoter 0.6 EPDnew 550.8 +0.2 185 0.1 GABPA TMEM202 PHBP20 GC15M072170
GH15I072604 Enhancer 0.6 FANTOM5 ENCODE 32.4 +206.9 206900 0.2 ZNF335 TCF7L2 PIR59605 LOC646665 LOC100420930 TMEM202 SENP8 HEXA MYO9A ENSG00000260534 LINC02259
GH15I072464 Enhancer 0.4 Ensembl 10.5 +66.3 66300 0.8 CEBPB CEBPG ENSG00000261187 GC15M072460 RPL12P35 HEXA TMEM202 ENSG00000260534 TMEM202-AS1 GC15M072170
GH15I072154 Promoter/Enhancer 1.9 FANTOM5 Ensembl ENCODE dbSUPER 1.4 -242.3 -242276 1.9 PKNOX1 GLI4 ZNF2 IRF4 ZNF48 GLIS2 ELK1 ARID2 ZNF143 DEK ENSG00000260173 SENP8 MYO9A ENSG00000261187 BBS4 TMEM202 CELF6 GRAMD2A
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around TMEM202 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the TMEM202 gene promoter:

Genomic Locations for TMEM202 Gene

Genomic Locations for TMEM202 Gene
chr15:72,398,101-72,408,367
(GRCh38/hg38)
Size:
10,267 bases
Orientation:
Plus strand
chr15:72,690,614-72,700,708
(GRCh37/hg19)

Genomic View for TMEM202 Gene

Genes around TMEM202 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TMEM202 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TMEM202 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM202 Gene

Proteins for TMEM202 Gene

  • Protein details for TMEM202 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NGA9-TM202_HUMAN
    Recommended name:
    Transmembrane protein 202
    Protein Accession:
    A6NGA9

    Protein attributes for TMEM202 Gene

    Size:
    273 amino acids
    Molecular mass:
    31353 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMEM202 Gene

Post-translational modifications for TMEM202 Gene

No Post-translational modifications

Other Protein References for TMEM202 Gene

No data available for DME Specific Peptides for TMEM202 Gene

Domains & Families for TMEM202 Gene

Gene Families for TMEM202 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Predicted membrane proteins
  • Transporters

Protein Domains for TMEM202 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for TMEM202 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TMEM202: view

No data available for UniProtKB/Swiss-Prot for TMEM202 Gene

Function for TMEM202 Gene

Phenotypes for TMEM202 Gene

GenomeRNAi human phenotypes for TMEM202:
genes like me logo Genes that share phenotypes with TMEM202: view

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TMEM202 Gene

Localization for TMEM202 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM202 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TMEM202 gene
Compartment Confidence
plasma membrane 3
peroxisome 2

Gene Ontology (GO) - Cellular Components for TMEM202 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM202: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for TMEM202 Gene

Pathways & Interactions for TMEM202 Gene

SuperPathways for TMEM202 Gene

No Data Available

Interacting Proteins for TMEM202 Gene

Gene Ontology (GO) - Biological Process for TMEM202 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TMEM202 Gene

Drugs & Compounds for TMEM202 Gene

No Compound Related Data Available

Transcripts for TMEM202 Gene

mRNA/cDNA for TMEM202 Gene

(3) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(11) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TMEM202 Gene

Transmembrane protein 202:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM202 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4
SP1:
SP2: -

Relevant External Links for TMEM202 Gene

GeneLoc Exon Structure for
TMEM202
ECgene alternative splicing isoforms for
TMEM202

Expression for TMEM202 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TMEM202 Gene

mRNA differential expression in normal tissues according to GTEx for TMEM202 Gene

This gene is overexpressed in Testis (x52.8).

Protein differential expression in normal tissues from HIPED for TMEM202 Gene

This gene is overexpressed in Platelet (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for TMEM202 Gene



Protein tissue co-expression partners for TMEM202 Gene

NURSA nuclear receptor signaling pathways regulating expression of TMEM202 Gene:

TMEM202

SOURCE GeneReport for Unigene cluster for TMEM202 Gene:

Hs.446069
genes like me logo Genes that share expression patterns with TMEM202: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TMEM202 Gene

Orthologs for TMEM202 Gene

This gene was present in the common ancestor of mammals.

Orthologs for TMEM202 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TMEM202 33 34
  • 98.52 (n)
dog
(Canis familiaris)
Mammalia TMEM202 33 34
  • 82.82 (n)
cow
(Bos Taurus)
Mammalia TMEM202 33 34
  • 81.84 (n)
mouse
(Mus musculus)
Mammalia Tmem202 33 16 34
  • 75.83 (n)
rat
(Rattus norvegicus)
Mammalia Tmem202 33
  • 75.67 (n)
oppossum
(Monodelphis domestica)
Mammalia TMEM202 34
  • 39 (a)
OneToOne
Species where no ortholog for TMEM202 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TMEM202 Gene

ENSEMBL:
Gene Tree for TMEM202 (if available)
TreeFam:
Gene Tree for TMEM202 (if available)

Paralogs for TMEM202 Gene

No data available for Paralogs for TMEM202 Gene

Variants for TMEM202 Gene

Sequence variations from dbSNP and Humsavar for TMEM202 Gene

SNP ID Clin Chr 15 pos Variation AA Info Type
rs1000487867 -- 72,399,018(+) C/T intron_variant
rs1000801066 -- 72,407,209(+) T/A coding_sequence_variant, missense_variant
rs1000884392 -- 72,406,865(+) A/C intron_variant
rs1000955948 -- 72,407,523(+) T/C intron_variant
rs1001084125 -- 72,400,566(+) A/C intron_variant

Structural Variations from Database of Genomic Variants (DGV) for TMEM202 Gene

Variant ID Type Subtype PubMed ID
nsv469704 CNV loss 16826518

Variation tolerance for TMEM202 Gene

Residual Variation Intolerance Score: 73.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.92; 48.99% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for TMEM202 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TMEM202

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TMEM202 Gene

Disorders for TMEM202 Gene

Additional Disease Information for TMEM202

No disorders were found for TMEM202 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TMEM202 Gene

Publications for TMEM202 Gene

  1. Analysis of the DNA sequence and duplication history of human chromosome 15. (PMID: 16572171) Zody MC … Nusbaum C (Nature 2006) 4 58

Products for TMEM202 Gene

Sources for TMEM202 Gene

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