Free for academic non-profit institutions. Other users need a Commercial license

Aliases for TMEM200B Gene

Aliases for TMEM200B Gene

  • Transmembrane Protein 200B 2 3 5
  • Two Transmembrane Domain-Containing Family Member B 3 4
  • Transmembrane Protein TTMA 3 4
  • TTMB 3 4
  • Two Transmembrane B 3

External Ids for TMEM200B Gene

Previous GeneCards Identifiers for TMEM200B Gene

  • GC01M029318
  • GC01M029445
  • GC01M027698

Summaries for TMEM200B Gene

GeneCards Summary for TMEM200B Gene

TMEM200B (Transmembrane Protein 200B) is a Protein Coding gene. An important paralog of this gene is TMEM200A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM200B Gene

Genomics for TMEM200B Gene

Regulatory Elements for TMEM200B Gene

Enhancers for TMEM200B Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around TMEM200B on UCSC Golden Path with GeneCards custom track

Genomic Location for TMEM200B Gene

29,119,425 bp from pter
29,129,134 bp from pter
9,710 bases
Minus strand

Genomic View for TMEM200B Gene

Genes around TMEM200B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TMEM200B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TMEM200B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM200B Gene

Proteins for TMEM200B Gene

  • Protein details for TMEM200B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Transmembrane protein 200B
    Protein Accession:
    Secondary Accessions:
    • Q6P2G8
    • Q6P2Q5

    Protein attributes for TMEM200B Gene

    307 amino acids
    Molecular mass:
    32750 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TMEM200B Gene

Proteomics data for TMEM200B Gene at MOPED

Post-translational modifications for TMEM200B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TMEM200B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TMEM200B Gene

Domains & Families for TMEM200B Gene

Protein Domains for TMEM200B Gene


Suggested Antigen Peptide Sequences for TMEM200B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the TMEM200 family.
  • Belongs to the TMEM200 family.
genes like me logo Genes that share domains with TMEM200B: view

No data available for Gene Families for TMEM200B Gene

Function for TMEM200B Gene

genes like me logo Genes that share phenotypes with TMEM200B: view

Animal Model Products

CRISPR Products

miRNA for TMEM200B Gene

miRTarBase miRNAs that target TMEM200B

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TMEM200B Gene

Localization for TMEM200B Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM200B Gene

Membrane; Multi-pass membrane protein.

No data available for Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for TMEM200B Gene

Pathways & Interactions for TMEM200B Gene

SuperPathways for TMEM200B Gene

No Data Available

Interacting Proteins for TMEM200B Gene

Gene Ontology (GO) - Biological Process for TMEM200B Gene


No data available for Pathways by source and SIGNOR curated interactions for TMEM200B Gene

Drugs & Compounds for TMEM200B Gene

No Compound Related Data Available

Transcripts for TMEM200B Gene

Unigene Clusters for TMEM200B Gene

Transmembrane protein 200B:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM200B Gene

No ASD Table

Relevant External Links for TMEM200B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TMEM200B Gene

mRNA expression in normal human tissues for TMEM200B Gene

mRNA differential expression in normal tissues according to GTEx for TMEM200B Gene

This gene is overexpressed in Uterus (x5.0).

SOURCE GeneReport for Unigene cluster for TMEM200B Gene Hs.712722

genes like me logo Genes that share expression patterns with TMEM200B: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for TMEM200B Gene

Orthologs for TMEM200B Gene

This gene was present in the common ancestor of chordates.

Orthologs for TMEM200B Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia TMEM200B 35
  • 90.88 (n)
  • 93.49 (a)
TMEM200B 36
  • 93 (a)
(Canis familiaris)
Mammalia TMEM200B 35
  • 92.51 (n)
  • 95.11 (a)
TMEM200B 36
  • 95 (a)
(Mus musculus)
Mammalia Tmem200b 35
  • 82.16 (n)
  • 88.38 (a)
Tmem200b 16
Tmem200b 36
  • 88 (a)
(Rattus norvegicus)
Mammalia Tmem200b 35
  • 82.86 (n)
  • 89.44 (a)
(Monodelphis domestica)
Mammalia TMEM200B 36
  • 58 (a)
(Pan troglodytes)
Mammalia TMEM200B 36
  • 100 (a)
(Gallus gallus)
Aves TMEM200B 36
  • 34 (a)
(Anolis carolinensis)
Reptilia TMEM200B 36
  • 36 (a)
(Danio rerio)
Actinopterygii TMEM200B 36
  • 21 (a)
Species with no ortholog for TMEM200B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TMEM200B Gene

Gene Tree for TMEM200B (if available)
Gene Tree for TMEM200B (if available)

Paralogs for TMEM200B Gene

Paralogs for TMEM200B Gene

genes like me logo Genes that share paralogs with TMEM200B: view

Variants for TMEM200B Gene

Sequence variations from dbSNP and Humsavar for TMEM200B Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs472843 -- 29,130,966(+) gattg(G/T)tgtgt upstream-variant-2KB
rs478102 -- 29,124,099(-) TGGGG(A/G)TGGCA intron-variant, upstream-variant-2KB, reference, missense
rs484000 -- 29,125,625(+) GCTCC(A/G)GCGTC intron-variant, upstream-variant-2KB
rs538108 -- 29,122,125(+) TGTTC(C/T)CTGGC intron-variant
rs539152 -- 29,127,031(+) tgtgt(C/T)tcaaa intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TMEM200B Gene

Variant ID Type Subtype PubMed ID
nsv509091 CNV Insertion 20534489

Variation tolerance for TMEM200B Gene

Gene Damage Index Score: 1.53; 29.70% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for TMEM200B Gene

Disorders for TMEM200B Gene

Relevant External Links for TMEM200B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for TMEM200B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TMEM200B Gene

Publications for TMEM200B Gene

  1. Candidate psychiatric illness genes identified in patients with pericentric inversions of chromosome 18. (PMID: 15722956) Pickard B.S. … Muir W.J. (Psychiatr. Genet. 2005) 2 3 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for TMEM200B Gene

Sources for TMEM200B Gene