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Aliases for TMEM200A Gene

Aliases for TMEM200A Gene

  • Transmembrane Protein 200A 2 3
  • KIAA1913 2 3 4
  • Two Transmembrane C 3
  • TTMA 3
  • TTMC 3

External Ids for TMEM200A Gene

Previous Symbols for TMEM200A Gene

  • KIAA1913

Summaries for TMEM200A Gene

GeneCards Summary for TMEM200A Gene

TMEM200A (Transmembrane Protein 200A) is a Protein Coding gene. An important paralog of this gene is TMEM200B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM200A Gene

Genomics for TMEM200A Gene

Genomic Location for TMEM200A Gene

Start:
130,365,734 bp from pter
End:
130,443,424 bp from pter
Size:
77,691 bases
Orientation:
Plus strand

Genomic View for TMEM200A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMEM200A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM200A Gene

Regulatory Elements for TMEM200A Gene

Proteins for TMEM200A Gene

  • Protein details for TMEM200A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q86VY9-T200A_HUMAN
    Recommended name:
    Transmembrane protein 200A
    Protein Accession:
    Q86VY9
    Secondary Accessions:
    • Q96PX5

    Protein attributes for TMEM200A Gene

    Size:
    491 amino acids
    Molecular mass:
    54356 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB67806.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for TMEM200A Gene

Proteomics data for TMEM200A Gene at MOPED

Post-translational modifications for TMEM200A Gene

  • Modification sites at PhosphoSitePlus
  • Glycosylation at Asn100

Other Protein References for TMEM200A Gene

No data available for DME Specific Peptides for TMEM200A Gene

Domains for TMEM200A Gene

Protein Domains for TMEM200A Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

T200A_HUMAN
Family:
  • Belongs to the TMEM200 family.:
    • Q86VY9
genes like me logo Genes that share domains with TMEM200A: view

No data available for Gene Families for TMEM200A Gene

Function for TMEM200A Gene

Phenotypes for TMEM200A Gene

genes like me logo Genes that share phenotypes with TMEM200A: view

miRNA for TMEM200A Gene

miRTarBase miRNAs that target TMEM200A

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targeting and HOMER Transcription for TMEM200A Gene

Localization for TMEM200A Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM200A Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TMEM200A Gene COMPARTMENTS Subcellular localization image for TMEM200A gene
Compartment Confidence
plasma membrane 3
endoplasmic reticulum 1
mitochondrion 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for TMEM200A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM200A: view

Pathways for TMEM200A Gene

SuperPathways for TMEM200A Gene

No Data Available

Interacting Proteins for TMEM200A Gene

Gene Ontology (GO) - Biological Process for TMEM200A Gene

None

No data available for Pathways by source for TMEM200A Gene

Transcripts for TMEM200A Gene

Unigene Clusters for TMEM200A Gene

Transmembrane protein 200A:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM200A Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b · 5c · 5d
SP1: - -
SP2: - -
SP3: - - -
SP4: - - - -
SP5:

Relevant External Links for TMEM200A Gene

GeneLoc Exon Structure for
TMEM200A
ECgene alternative splicing isoforms for
TMEM200A

Expression for TMEM200A Gene

mRNA expression in normal human tissues for TMEM200A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for TMEM200A Gene

This gene is overexpressed in Adrenal Gland (5.7) and Uterus (5.6).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for TMEM200A Gene

SOURCE GeneReport for Unigene cluster for TMEM200A Gene Hs.591341

mRNA Expression by UniProt/SwissProt for TMEM200A Gene

Q86VY9-T200A_HUMAN
Tissue specificity: Expressed in cerebellum.
genes like me logo Genes that share expressions with TMEM200A: view

Orthologs for TMEM200A Gene

This gene was present in the common ancestor of chordates.

Orthologs for TMEM200A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TMEM200A 36
  • 99.52 (n)
  • 99.39 (a)
TMEM200A 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia TMEM200A 37
  • 93 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TMEM200A 36
  • 85.47 (n)
  • 90.63 (a)
TMEM200A 37
  • 91 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tmem200a 36
  • 82.01 (n)
  • 90.63 (a)
Tmem200a 16
Tmem200a 37
  • 91 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia TMEM200A 37
  • 87 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia TMEM200A 37
  • 82 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Tmem200a 36
  • 81.92 (n)
  • 90.93 (a)
chicken
(Gallus gallus)
Aves TMEM200A 36
  • 76.55 (n)
  • 79.96 (a)
TMEM200A 37
  • 80 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia TMEM200A 37
  • 76 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia tmem200a 36
  • 68.58 (n)
  • 72.28 (a)
zebrafish
(Danio rerio)
Actinopterygii tmem200a 36
  • 62.98 (n)
  • 65.78 (a)
tmem200a 37
  • 63 (a)
OneToOne
Species with no ortholog for TMEM200A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TMEM200A Gene

ENSEMBL:
Gene Tree for TMEM200A (if available)
TreeFam:
Gene Tree for TMEM200A (if available)

Paralogs for TMEM200A Gene

Paralogs for TMEM200A Gene

genes like me logo Genes that share paralogs with TMEM200A: view

Variants for TMEM200A Gene

Sequence variations from dbSNP and Humsavar for TMEM200A Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs169785 -- 130,390,043(+) GGTTT(C/G)TTAGA intron-variant
rs172401 -- 130,408,184(+) GGGCA(C/G)AGCAG intron-variant
rs184130 -- 130,383,869(+) tccca(G/T)cactt intron-variant
rs188376 -- 130,408,071(+) GAGCA(C/G)TCTGG intron-variant
rs192665 -- 130,369,793(+) ATAGA(A/T)ATCTA intron-variant

Relevant External Links for TMEM200A Gene

HapMap Linkage Disequilibrium report
TMEM200A

No data available for Structural Variations from Database of Genomic Variants (DGV) for TMEM200A Gene

Disorders for TMEM200A Gene

Relevant External Links for TMEM200A

Genetic Association Database (GAD)
TMEM200A
genes like me logo Genes that share disorders with TMEM200A: view

No data available for UniProtKB/Swiss-Prot for TMEM200A Gene

Publications for TMEM200A Gene

  1. Candidate psychiatric illness genes identified in patients with pericentric inversions of chromosome 18. (PMID: 15722956) Pickard B.S. … Muir W.J. (Psychiatr. Genet. 2005) 2 3
  2. Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins. (PMID: 11572484) Nagase T. … Ohara O. (DNA Res. 2001) 3 4
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. Genome-wide association analysis demonstrates the highly polygenic character of age-related hearing impairment. (PMID: 24939585) Fransen E. … Friedman R.A. (Eur. J. Hum. Genet. 2015) 3

Products for TMEM200A Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate TMEM200A
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat
  • Predesigned siRNA for gene silencing in human,mouse,rat for TMEM200A
  • Block miRNA regulation of TMEM200A using miScript Target Protectors

Sources for TMEM200A Gene

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