Aliases for TMEM2 Gene
External Ids for TMEM2 Gene
- HGNC: 11869
- Entrez Gene: 23670
- Ensembl: ENSG00000135048
- OMIM: 605835
- UniProtKB: Q9UHN6
Previous GeneCards Identifiers for TMEM2 Gene
- GC09M065342
- GC09M066154
- GC09M067868
- GC09M069755
- GC09M071527
- GC09M073488
- GC09M073371
- GC09M074298
- GC09M044121
Summaries for TMEM2 Gene
-
This gene encodes a type II transmembrane protein that belongs to the interferon-induced transmembrane (IFITM) protein superfamily. The encoded protein functions as a cell surface hyaluronidase that cleaves extracellular high molecular weight hyaluronan into intermediate size fragments before internalization and degradation in the lysosome. It also has an interferon-mediated antiviral function in humans through activation of the JAK STAT signaling pathway. The activation of this gene by transcription factor SOX4 in breast cancer cells has been shown to mediate the pathological effects of SOX4 on cancer progression. Naturally occurring mutations in this gene are associated with autosomal recessive non-syndromic hearing loss. [provided by RefSeq, Mar 2017]
GeneCards Summary for TMEM2 Gene
TMEM2 (Transmembrane Protein 2) is a Protein Coding gene. Diseases associated with TMEM2 include Deafness, Autosomal Recessive 7 and Benign Familial Infantile Epilepsy. An important paralog of this gene is CEMIP.
UniProtKB/Swiss-Prot for TMEM2 Gene
-
Cell surface hyaluronidase that mediates the initial cleavage of extracellular high-molecular-weight hyaluronan into intermediate-size hyaluronan of approximately 5 kDa fragments (PubMed:28246172). Acts as a regulator of angiogenesis and heart morphogenesis by mediating degradation of extracellular hyaluronan, thereby regulating VEGF signaling (By similarity). Is very specific to hyaluronan; not able to cleave chondroitin sulfate or dermatan sulfate (PubMed:28246172).
No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM2 Gene
Genomics for TMEM2 Gene
GeneHancer (GH) Regulatory Elements for TMEM2 Gene
Promoters and enhancers for TMEM2 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around TMEM2 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the TMEM2 gene promoter:
Regulatory Element Products
Genomic Locations for TMEM2 Gene
Genomic Locations for TMEM2 Gene
- chr9:71,683,366-71,816,690
- (GRCh38/hg38)
- Size:
- 133,325 bases
- Orientation:
- Minus strand
- chr9:74,298,282-74,431,606
- (GRCh37/hg19)
Genomic View for TMEM2 Gene
Genes around TMEM2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 9q21.13 by Ensembl
- 9q21.13 by Entrez Gene
- 9q21.13 by HGNC
TMEM2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for TMEM2 Gene
Proteins for TMEM2 Gene
-
Protein details for TMEM2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9UHN6-TMEM2_HUMAN
- Recommended name:
- Cell surface hyaluronidase
- Protein Accession:
- Q9UHN6
- A6H8W9
- B2RTQ6
- Q5T838
- Q5T839
- Q5T840
- Q5T841
- Q8NBP6
- Q9P2D5
Protein attributes for TMEM2 Gene
- Size:
- 1383 amino acids
- Molecular mass:
- 154374 Da
- Cofactor:
- Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=BAA92650.2; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=BAC11574.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=CAI15172.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAI15173.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAI15174.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAI15175.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
Protein Expression for TMEM2 Gene
Post-translational modifications for TMEM2 Gene
- Glycosylation at posLast=248248, posLast=292292, isoforms=2914, isoforms=2980, and isoforms=21234
Other Protein References for TMEM2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for TMEM2
- Novus Biologicals Antibodies for TMEM2
-
Abcam antibodies for TMEM2
- Invitrogen Antibodies for TMEM2
- GeneTex TMEM2 antibody for TMEM2
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for TMEM2
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- Search GeneTex for Proteins for TMEM2
Assay Products
- antibodies-online: Search results for 3 available TMEM2 Elisa Kits ranked by validation data
- Compare Top TMEM2 Elisa Kits
-
Quality Products:
No data available for DME Specific Peptides for TMEM2 Gene
Domains & Families for TMEM2 Gene
Gene Families for TMEM2 Gene
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Predicted membrane proteins
Protein Domains for TMEM2 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for TMEM2 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9UHN6- Family:
-
- Belongs to the TMEM2 family.
Function for TMEM2 Gene
Molecular function for TMEM2 Gene
- UniProtKB/Swiss-Prot BiophysicochemicalProperties:
- pH dependence: Optimum pH is 6-7. {ECO:0000269 PubMed:28246172};
- UniProtKB/Swiss-Prot CatalyticActivity:
- Random hydrolysis of (1->4)-linkages between N-acetyl-beta-D-glucosamine and D-glucuronate residues in hyaluronate.
- UniProtKB/Swiss-Prot Function:
- Cell surface hyaluronidase that mediates the initial cleavage of extracellular high-molecular-weight hyaluronan into intermediate-size hyaluronan of approximately 5 kDa fragments (PubMed:28246172). Acts as a regulator of angiogenesis and heart morphogenesis by mediating degradation of extracellular hyaluronan, thereby regulating VEGF signaling (By similarity). Is very specific to hyaluronan; not able to cleave chondroitin sulfate or dermatan sulfate (PubMed:28246172).
Enzyme Numbers (IUBMB) for TMEM2 Gene
Phenotypes From GWAS Catalog for TMEM2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004415 | hyalurononglucosaminidase activity | IEA,IDA | 28246172 |
| GO:0005509 | calcium ion binding | IDA | 28246172 |
| GO:0016787 | hydrolase activity | IEA | -- |
| GO:0016798 | hydrolase activity, acting on glycosyl bonds | IEA | -- |
| GO:0045296 | cadherin binding | IDA | 25468996 |
Phenotypes for TMEM2 Gene
- GenomeRNAi human phenotypes for TMEM2:
Animal Model Products
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-
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CRISPR Products
-
OriGene CRISPR knockouts for TMEM2
- genomics-online: gRNA clones - Search results for 96 available TMEM2 gene related products
- Overview of 96 available TMEM2 gene related products
- Applied Biological Materials CRISPR for TMEM2
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for TMEM2
- GenScript: Design CRISPR guide RNA sequences for TMEM2
miRNA for TMEM2 Gene
- miRTarBase miRNAs that target TMEM2
-
- hsa-let-7b-5p (MIRT001585)
- hsa-mir-30a-3p (MIRT001762)
- hsa-mir-215-5p (MIRT024372)
- hsa-mir-196a-5p (MIRT026078)
- hsa-mir-192-5p (MIRT026372)
- hsa-mir-98-5p (MIRT027580)
- hsa-mir-26b-5p (MIRT029299)
- hsa-mir-21-5p (MIRT030825)
- hsa-let-7d-5p (MIRT032147)
- hsa-mir-331-3p (MIRT043348)
- hsa-mir-125b-5p (MIRT046046)
- hsa-mir-519c-3p (MIRT107945)
- hsa-mir-519b-3p (MIRT107948)
- hsa-mir-519a-3p (MIRT107955)
- hsa-mir-32-3p (MIRT228700)
- hsa-mir-5587-5p (MIRT465899)
- hsa-mir-603 (MIRT542629)
- hsa-mir-8485 (MIRT542630)
- hsa-mir-6759-3p (MIRT610311)
- hsa-mir-519e-5p (MIRT652454)
- hsa-mir-515-5p (MIRT652455)
- hsa-mir-302d-5p (MIRT652456)
- hsa-mir-302b-5p (MIRT652457)
- hsa-mir-942-5p (MIRT652458)
- hsa-mir-5695 (MIRT652459)
- hsa-mir-519d-5p (MIRT652460)
- hsa-mir-4762-5p (MIRT652461)
- hsa-mir-141-5p (MIRT652462)
- hsa-mir-5580-3p (MIRT652463)
- hsa-mir-186-5p (MIRT652464)
- hsa-mir-3133 (MIRT652465)
- hsa-mir-2113 (MIRT698242)
- hsa-mir-3682-5p (MIRT698243)
- hsa-mir-19b-3p (MIRT698244)
- hsa-mir-19a-3p (MIRT698245)
- hsa-mir-4696 (MIRT698246)
- hsa-mir-617 (MIRT698247)
- hsa-mir-570-3p (MIRT698248)
- hsa-mir-302a-5p (MIRT698249)
- hsa-mir-138-1-3p (MIRT698250)
- hsa-mir-499b-5p (MIRT698251)
- hsa-mir-4714-3p (MIRT698252)
- hsa-mir-454-3p (MIRT698253)
- hsa-mir-4295 (MIRT698254)
- hsa-mir-3666 (MIRT698255)
- hsa-mir-301b-3p (MIRT698256)
- hsa-mir-301a-3p (MIRT698257)
- hsa-mir-130b-3p (MIRT698258)
- hsa-mir-130a-3p (MIRT698259)
- hsa-mir-6882-5p (MIRT698260)
- hsa-mir-7-2-3p (MIRT698261)
- hsa-mir-7-1-3p (MIRT698262)
- hsa-mir-5688 (MIRT698263)
- hsa-mir-495-3p (MIRT698264)
- hsa-mir-548as-3p (MIRT698265)
- hsa-mir-585-5p (MIRT698266)
- hsa-mir-873-5p (MIRT698267)
- hsa-mir-198 (MIRT698268)
- hsa-mir-2861 (MIRT698269)
- hsa-mir-5589-3p (MIRT698270)
- hsa-mir-571 (MIRT698271)
- hsa-mir-219a-1-3p (MIRT698272)
- hsa-mir-4487 (MIRT698273)
- hsa-mir-558 (MIRT698274)
- hsa-mir-3160-3p (MIRT698275)
- hsa-mir-4682 (MIRT698276)
- hsa-mir-4673 (MIRT698277)
- hsa-mir-4645-5p (MIRT698278)
- hsa-mir-4742-5p (MIRT698279)
- hsa-mir-556-5p (MIRT698280)
- hsa-mir-4761-3p (MIRT698281)
- hsa-mir-3972 (MIRT698282)
- hsa-mir-1202 (MIRT698283)
- hsa-mir-4715-3p (MIRT698284)
- hsa-mir-6852-3p (MIRT698285)
- hsa-mir-3909 (MIRT698286)
- hsa-mir-6131 (MIRT698287)
- hsa-mir-222-3p (MIRT698288)
- hsa-mir-221-3p (MIRT698289)
- hsa-mir-548v (MIRT698290)
- hsa-mir-187-5p (MIRT698291)
- hsa-mir-3194-5p (MIRT698292)
- hsa-mir-7152-3p (MIRT698293)
- hsa-mir-520f-5p (MIRT698294)
- hsa-mir-4509 (MIRT698295)
- hsa-mir-4744 (MIRT698296)
- hsa-mir-551b-3p (MIRT698297)
- hsa-mir-551a (MIRT698298)
- hsa-mir-3691-3p (MIRT698299)
- hsa-mir-484 (MIRT698300)
- hsa-mir-3155b (MIRT698301)
- hsa-mir-3155a (MIRT698302)
- hsa-mir-4691-3p (MIRT698303)
- hsa-mir-5697 (MIRT698304)
- hsa-mir-4761-5p (MIRT698305)
- hsa-mir-338-5p (MIRT698306)
- hsa-mir-7161-5p (MIRT698307)
- hsa-mir-548u (MIRT698308)
- hsa-mir-4465 (MIRT698309)
- hsa-mir-26a-5p (MIRT698310)
- hsa-mir-1297 (MIRT698311)
- hsa-mir-18b-5p (MIRT698312)
- hsa-mir-18a-5p (MIRT698313)
- hsa-mir-4735-3p (MIRT698314)
miRNA Products
- Search ViGene Biosciences for TMEM2
Inhibitory RNA Products
- Origene RNAi, shrna, and sirna products in human, mouse, rat for TMEM2
- Browse OriGene Inhibitory RNA Products For TMEM2
- genomics-online: shRNA clones - Search results for 96 available TMEM2 gene related products
- Overview of 96 available TMEM2 gene related products
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ViGene Biosciences ready-to-package AAV shRNAs for TMEM2 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
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Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
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Horizon Cell Lines for TMEM2
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ViGene Biosciences adenoviral particle packaged cDNA for TMEM2 gene
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-
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No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TMEM2 Gene
Localization for TMEM2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for TMEM2 Gene
- Cell membrane; Single-pass type II membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| extracellular | 5 |
| cytosol | 4 |
| nucleus | 1 |
- Cytosol (2)
- Vesicles (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005886 | plasma membrane | IEA | -- |
| GO:0005887 | integral component of plasma membrane | IDA | 28246172 |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA,TAS | 10767548 |
| GO:0070062 | extracellular exosome | HDA,IDA | 19056867 |
Pathways & Interactions for TMEM2 Gene
No Data Available
Interacting Proteins for TMEM2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001525 | angiogenesis | IEA | -- |
| GO:0007275 | multicellular organism development | IEA | -- |
| GO:0008152 | metabolic process | IEA | -- |
| GO:0030214 | hyaluronan catabolic process | IDA | 28246172 |
| GO:1903670 | regulation of sprouting angiogenesis | ISS | -- |
No data available for Pathways by source and SIGNOR curated interactions for TMEM2 Gene
Transcripts for TMEM2 Gene
mRNA/cDNA for TMEM2 Gene
- (4) REFSEQ mRNAs :
- (12) Additional mRNA sequences :
- (184) Selected AceView cDNA sequences:
- (13) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for TMEM2 Gene
CRISPR Products
-
OriGene CRISPR knockouts for TMEM2
- genomics-online: gRNA clones - Search results for 96 available TMEM2 gene related products
- Overview of 96 available TMEM2 gene related products
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-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for TMEM2
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miRNA Products
- Search ViGene Biosciences for TMEM2
Inhibitory RNA Products
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- genomics-online: shRNA clones - Search results for 96 available TMEM2 gene related products
- Overview of 96 available TMEM2 gene related products
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ViGene Biosciences ready-to-package AAV shRNAs for TMEM2 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
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-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for TMEM2 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Brain (Nervous System)
- Neural Tube (Nervous System)
-
Heart (Cardiovascular System)
- Endocardial Tube Cells Endocardium
- Bone (Muscoskeletal System)
- Neural Ectoderm (Nervous System)
-
Placenta (Extraembryonic Tissues)
-
Gall Bladder (Hepatobiliary System)
-
Liver (Hepatobiliary System)
This gene is overexpressed in Breast (30.2) and Nasal epithelium (25.5).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for TMEM2 Gene
NURSA nuclear receptor signaling pathways regulating expression of TMEM2 Gene:
TMEM2SOURCE GeneReport for Unigene cluster for TMEM2 Gene:
Hs.494146mRNA Expression by UniProt/SwissProt for TMEM2 Gene:
Q9UHN6-TMEM2_HUMAN
Tissue specificity:
Widely expressed.
Evidence on tissue expression from TISSUES for TMEM2 Gene
- Nervous system(4.2)
- Intestine(2.4)
Primer Products
-
OriGene qPCR primer pairs for TMEM2
No data available for mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for TMEM2 Gene
Orthologs for TMEM2 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | TMEM2 33 34 |
|
||
| cow (Bos Taurus) |
Mammalia | TMEM2 33 34 |
|
||
| dog (Canis familiaris) |
Mammalia | TMEM2 33 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Tmem2 33 16 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Tmem2 33 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | TMEM2 34 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | TMEM2 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | LOC427250 33 |
|
||
| TMEM2 34 |
|
OneToOne | |||
| lizard (Anolis carolinensis) |
Reptilia | TMEM2 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | tmem2 33 |
|
||
| Str.19937 33 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.23798 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | tmem2 33 34 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.3786 34 |
|
OneToMany |
- Species where no ortholog for TMEM2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for TMEM2 Gene
(1) SIMAP similar genes for TMEM2 Gene using alignment to 6 proteins:
Variants for TMEM2 Gene
| SNP ID | Clin | Chr 09 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs146439095 | uncertain-significance, not specified | 71,745,561(-) | T/A/C | coding_sequence_variant, missense_variant | |
| rs36080695 | benign, not specified | 71,685,396(-) | AAAAAAAAAAAAAAAAAA/AAAAAAAAAAAAAAAA/AAAAAAAAAAAAAAAAA/AAAAAAAAAAAAAAAAAAA/AAAAAAAAAAAAAAAAAAAA/AAAAAAAAAAAAAAAAAAAAA/AAAAAAAAAAAAAAAAAAAAAA | intron_variant | |
| rs1000027792 | -- | 71,702,461(-) | T/C | intron_variant | |
| rs1000092378 | -- | 71,751,910(-) | C/G | intron_variant | |
| rs1000113205 | -- | 71,707,444(-) | C/G | intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2677935 | CNV | deletion | 23128226 |
| esv3544903 | CNV | deletion | 23714750 |
| nsv416322 | CNV | insertion | 16902084 |
| nsv507516 | OTHER | sequence alteration | 20534489 |
| nsv831617 | CNV | gain | 17160897 |
Residual Variation Intolerance Score:
8.09% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
16.12;
97.56% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for TMEM2 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TMEM2 Gene
Disorders for TMEM2 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| deafness, autosomal recessive 7 |
|
|
| benign familial infantile epilepsy |
|
|
| polycystic kidney disease 4 with or without hepatic disease |
|
|
Search TMEM2 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for TMEM2
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for TMEM2 Gene
Publications for TMEM2 Gene
- A mammalian homolog of the zebrafish transmembrane protein 2 (TMEM2) is the long-sought-after cell-surface hyaluronidase. (PMID: 28246172) Yamamoto H … Yamaguchi Y (The Journal of biological chemistry 2017) 2 3 4 58
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 44 58
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
- Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10718198) Nagase T … Ohara O (DNA research : an international journal for rapid publication of reports on genes and genomes 2000) 3 4 58
- Refining the DFNB7-DFNB11 deafness locus using intragenic polymorphisms in a novel gene, TMEM2. (PMID: 10767548) Scott DA … Smith RJ (Gene 2000) 3 4 58
Products for TMEM2 Gene
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- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for TMEM2
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse Sino Biological ELISA Kits
- Browse Sino Biological ELISA Pair Sets
- Browse Sino Biological CRO Services
- Browse Sino Biological Control Vectors
- Sino Biological Transfection Reagent
- Sino Biological Anti-His Tag Antibody
- Novus Biologicals Antibodies for TMEM2
- Novus Biologicals proteins for TMEM2
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Abcam antibodies for TMEM2
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Browse Antibodies at Cloud-Clone Corp.
- Browse Proteins at Cloud-Clone Corp.
- Browse Assay Kits at Cloud-Clone Corp.
- Browse Knockouts at Cloud-Clone Corp.
- Browse Knockins at Cloud-Clone Corp.
- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Invitrogen Antibodies for TMEM2
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- antibodies-online: Search results for 12 available TMEM2 Antibodies ranked by validation data
- Compare Top TMEM2 Antibodies
- antibodies-online: Search results for 3 available TMEM2 Elisa Kits ranked by validation data
- Compare Top TMEM2 Elisa Kits
- Quality Products:
- antibodies-online: Search results for available TMEM2 related products ranked by validation data
- GeneTex TMEM2 antibody for TMEM2
- Search GeneTex for Proteins for TMEM2
- ViGene Biosciences adenoviral particle packaged cDNA for TMEM2 gene
- ViGene Biosciences lentiviral particle packaged cDNA for TMEM2 gene
- ViGene Biosciences ready-to-package AAV shRNAs for TMEM2 gene
- Search ViGene Biosciences for TMEM2
- Horizon Cell Lines for TMEM2
- genomics-online: cdna clones - Search results for 96 available TMEM2 gene related products
- Overview of 96 available TMEM2 gene related products
- orf clones - Search results for 96 available TMEM2 gene related products
- Overview of 96 available TMEM2 gene related products
- genomics-online: gRNA clones - Search results for 96 available TMEM2 gene related products
- Overview of 96 available TMEM2 gene related products
- genomics-online: primer clones - Search results for 96 available TMEM2 gene related products
- Overview of 96 available TMEM2 gene related products
- genomics-online: shRNA clones - Search results for 96 available TMEM2 gene related products
- Overview of 96 available TMEM2 gene related products
Sources for TMEM2 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew