Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



TMEM198 Gene

protein-coding   GIFtS: 37
GCID: GC02P220408

Transmembrane Protein 198

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Transmembrane Protein 1981 2
TMEM198A2

External Ids:    HGNC: 337041   Entrez Gene: 1306122   Ensembl: ENSG000001887607   UniProtKB: Q66K663   

Export aliases for TMEM198 gene to outside databases

Previous GC identifers: GC02P220117 GC02P212261


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for TMEM198 Gene:
TMEM198 (transmembrane protein 198) is a protein-coding gene. Diseases associated with TMEM198 include malaria.

UniProtKB/Swiss-Prot: TM198_HUMAN, Q66K66
Function: Promotes LRP6 phosphorylation by casein kinases and thereby plays a role in Wnt signaling. May be a
membrane scaffold protein involved in the self-aggregation of LRP6 to further enhance its activity




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence:
NC_000002.12  NT_005403.18  NC_018913.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the TMEM198 gene promoter:
         Spz1   RFX1   HOXA3   Pax-5   STAT5A   PPAR-gamma1   HSF2   PPAR-gamma2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTMEM198 promoter sequence
   Search Chromatin IP Primers for TMEM198

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TMEM198


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q35   Ensembl cytogenetic band:  2q35   HGNC cytogenetic band: 2q35

TMEM198 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMEM198 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P220408:  view genomic region     (about GC identifiers)

Start:
220,408,385 bp from pter      End:
220,415,317 bp from pter
Size:
6,933 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: TM198_HUMAN, Q66K66 (See protein sequence)
Recommended Name: Transmembrane protein 198  
Size: 360 amino acids; 39475 Da
Subunit: Interacts with LRP6

Explore the universe of human proteins at neXtProt for TMEM198: NX_Q66K66

Explore proteomics data for TMEM198 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See TMEM198 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_001005209.1  
    ENSEMBL proteins: 
     ENSP00000343507   ENSP00000388087   ENSP00000362990   ENSP00000415186  

    TMEM198 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for TMEM198
    OriGene Custom MassSpec
    OriGene Custom Protein Services for TMEM198
    GenScript Custom Purified and Recombinant Proteins Services for TMEM198
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TMEM198

    TMEM198 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for TMEM198
    Search for Antibodies for TMEM198 at Abcam
    Cloud-Clone Corp. Antibodies for TMEM198
    Search ThermoFisher Antibodies for TMEM198
    Search LSBio for Antibodies for TMEM198

    TMEM198 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for TMEM198
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for TMEM198
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for TMEM198
    Cloud-Clone Corp. CLIAs for TMEM198


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    1 InterPro protein domain:
     IPR025256 DUF4203

    Graphical View of Domain Structure for InterPro Entry Q66K66

    ProtoNet protein and cluster: Q66K66

    UniProtKB/Swiss-Prot: TM198_HUMAN, Q66K66
    Similarity: Belongs to the TMEM198 family


    TMEM198 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TM198_HUMAN, Q66K66
    Function: Promotes LRP6 phosphorylation by casein kinases and thereby plays a role in Wnt signaling. May be a
    membrane scaffold protein involved in the self-aggregation of LRP6 to further enhance its activity

    Animal Models:

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TMEM198
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TMEM198

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TMEM198
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TMEM198

    miRNA
    Products:
        
    miRTarBase miRNAs that target TMEM198:
    hsa-mir-335-5p (MIRT017954)

    Block miRNA regulation of human, mouse, rat TMEM198 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TMEM198 (see all 21):
    hsa-miR-3910 hsa-miR-125a-5p hsa-miR-1271 hsa-miR-501-3p hsa-miR-4299 hsa-miR-340 hsa-miR-502-3p hsa-miR-124
    SwitchGear 3'UTR luciferase reporter plasmidTMEM198 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for TMEM198
    Predesigned siRNA for gene silencing in human, mouse, rat TMEM198

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for TMEM198

    Clone
    Products:
         
    OriGene clones in human, mouse for TMEM198 (see all 6)
    OriGene ORF clones in mouse, rat for TMEM198
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TMEM198 (NM_001005209)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM198
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM198

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for TMEM198
    Browse ESI BIO Cell Lines and PureStem Progenitors for TMEM198 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM198


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    TM198_HUMAN, Q66K66: Membrane; Multi-pass membrane protein (Potential). Cell membrane (By similarity).
    Cytoplasmic vesicle (By similarity). Note=Largely located to vesicle-like structures (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane IDA--
    GO:0016021integral component of membrane IEA--
    GO:0016023cytoplasmic membrane-bounded vesicle IDA--

    TMEM198 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TMEM198
    Interactions:

        Search GeneGlobe Interaction Network for TMEM198

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007275multicellular organismal development IEA--
    GO:0016055Wnt signaling pathway IEA--
    GO:0090263positive regulation of canonical Wnt signaling pathway IDA--

    TMEM198 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TMEM198 (TM198)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for TMEM198 gene: 
    NM_001005209.1  

    Unigene Cluster for TMEM198:

    Transmembrane protein 198
    Hs.446664  [show with all ESTs]
    Unigene Representative Sequence: BC068567
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000344458(uc002vme.3) ENST00000421791 ENST00000373883(uc002vmf.3)
    ENST00000451952
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat TMEM198 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TMEM198 (see all 21):
    hsa-miR-3910 hsa-miR-125a-5p hsa-miR-1271 hsa-miR-501-3p hsa-miR-4299 hsa-miR-340 hsa-miR-502-3p hsa-miR-124
    SwitchGear 3'UTR luciferase reporter plasmidTMEM198 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for TMEM198
    Predesigned siRNA for gene silencing in human, mouse, rat TMEM198
    Clone
    Products:
         
    OriGene clones in human, mouse for TMEM198 (see all 6)
    OriGene ORF clones in mouse, rat for TMEM198
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TMEM198 (NM_001005209)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM198
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM198
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for TMEM198
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMEM198
      QuantiTect SYBR Green Assays in human, mouse, rat TMEM198
      QuantiFast Probe-based Assays in human, mouse, rat TMEM198

    Additional mRNA sequence: 

    AK123175.1 AK302369.1 BC068567.1 BC080573.1 

    10 DOTS entries:

    DT.100666060  DT.95237072  DT.91686634  DT.100754539  DT.80100285  DT.100754541  DT.40242615  DT.95137550 
    DT.95208865  DT.40242617 

    Selected AceView cDNA sequences (see all 75):

    AI376907 BF515430 BF115238 AI343486 BM672313 BM703284 AW139465 BM142150 
    NM_001005209 BG056047 CR592699 CB130374 CR597020 BC080573 CR596918 BM664765 
    BC068567 BI821451 BX353651 AL529575 BM806020 AI498947 AI888691 AI214980 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for TMEM198    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c ^ 3a · 3b ^ 4 ^ 5 ^ 6
    SP1:                                                                  
    SP2:                    -                                             
    SP3:                                -                                 
    SP4:                                                                  


    ECgene alternative splicing isoforms for TMEM198

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    TMEM198 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    TMEM198 Expression
    About this image

    TMEM198 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TMEM198 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.446664
        Custom PCR Arrays for TMEM198
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for TMEM198
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMEM198
    QuantiTect SYBR Green Assays in human, mouse, rat TMEM198
    QuantiFast Probe-based Assays in human, mouse, rat TMEM198
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM198

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals.

    Orthologs for TMEM198 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tmem1981 , 5 transmembrane protein 1981, 5 90.28(n)1
    97.78(a)1
      1 (39.15 cM)5
    3199981  NM_177056.41  NP_796030.11 
     754795325 
    chicken
    (Gallus gallus)
    Aves TMEM1981 transmembrane protein 198 69.01(n)
    63.38(a)
      769377  XM_001232636.3  XP_001232637.3 
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    64(a)
    1 → many
    1(94606868-94631679)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.297302 Xenopus laevis transcribed sequences 71.11(n)    BJ068161.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.74712 Transcribed sequences 73.81(n)    BG304666.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG142346
    --
    20(a)
    1 ↔ 1
    X(19629603-19634489)


    ENSEMBL Gene Tree for TMEM198 (if available)
    TreeFam Gene Tree for TMEM198 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for TMEM198 gene

    TMEM198 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for TMEM198
    PGOHUM00000233452


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for TMEM198 (see all 202)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs75812511,2
    C,F,H--219787393(+) CAAAAA/GGACAA 1 -- us2k114Minor allele frequency- G:0.05NA WA CSA EA 379
    rs1886410111,2
    --219787561(+) CATTTC/GGGAGA 1 -- us2k10--------
    rs1150416851,2
    F--219787616(+) TCCGGG/AGTTCG 1 -- us2k11Minor allele frequency- A:0.03WA 118
    rs1386328571,2
    --219787775(+) TGCCTA/CACATA 1 -- us2k10--------
    rs1493169381,2
    --219787869(+) CTTACC/TTTTTG 1 -- us2k10--------
    rs779430801,2
    C--219787894(+) AAATTG/TCAGAA 1 -- us2k10--------
    rs1925924051,2
    --219788016(+) ACCCAC/TTCAGG 1 -- us2k10--------
    rs1378607241,2
    C--219788089(+) CCTATA/GTATAA 1 -- us2k10--------
    rs116859121,2
    C,F,A,H--219788185(+) CCAGTG/AAGTTC 1 -- us2k121Minor allele frequency- A:0.49NS EA NA WA CSA 2345
    rs109328101,2
    C--219788367(+) CCCAGG/TGGGTA 1 -- us2k13Minor allele frequency- T:0.19WA NA 240

    HapMap Linkage Disequilibrium report for TMEM198 (220408385 - 220415317 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 7 variations for TMEM198:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv508887CNV Insertion20534489
    dgv4438n71CNV Loss21882294
    nsv875876CNV Loss21882294
    nsv520958CNV Loss19592680
    nsv834545CNV Loss17160897
    nsv875875CNV Loss21882294
    nsv821906CNV Gain20364138

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TMEM198
    DNA2.0 Custom Variant and Variant Library Synthesis for TMEM198

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    1 disease for TMEM198:    
    About MalaCards
    malaria


    TMEM198 for disorders           About GeneDecksing


    Export disorders for TMEM198 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for TMEM198 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with TMEM198)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Transmembrane protein 198 promotes LRP6 phosphorylation and Wnt signaling activation. (PubMed id 21536646)1, 2 Liang J.... Wu W. (Mol. Cell. Biol. 2011)
    2. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (Genomics 2007)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    5. (PubMed id )2 

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 130612 HGNC: 33704 AceView: MGC99813 Ensembl:ENSG00000188760 euGenes: HUgn130612
    ECgene: TMEM198 H-InvDB: TMEM198

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for TMEM198 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for TMEM198 gene:
    Search GeneIP for patents involving TMEM198

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for TMEM198  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for TMEM198  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for TMEM198  
     OriGene qSTAR qPCR primer pairs in human, mouse for TMEM198   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for TMEM198   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for TMEM198   OriGene Custom Protein Services for TMEM198  

     
     
     Block miRNA regulation of human, mouse, rat TMEM198 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing TMEM198
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TMEM198 Predesigned siRNA for gene silencing in human, mouse, rat TMEM198
     QuantiFast Probe-based Assays in human, mouse, rat TMEM198 QuantiTect SYBR Green Assays in human, mouse, rat TMEM198
     Custom PCR Arrays for TMEM198 Search Chromatin IP Primers for TMEM198
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMEM198  Search GeneGlobe Interaction Network for TMEM198
     Regulatory tfbs in TMEM198 promoter
     GenScript Custom Purified and Recombinant Proteins Services for TMEM198 GenScript cDNA clones with any tag delivered in your preferred vector for TMEM198
     GenScript Custom Assay Services for TMEM198 GenScript Custom overexpressing Cell Line Services for TMEM198
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for TMEM198 (TM198)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Biologicals
     Novus Tissue Slides
     Search for Antibodies for TMEM198 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for TMEM198
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for TMEM198
     Antibodies for TMEM198
     ELISAs for TMEM198
     CLIAs for TMEM198



     Browse ESI BIO Cell Lines and PureStem Progenitors for TMEM198
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM198
     SwitchGear 3'UTR luciferase reporter plasmids for TMEM198
     SwitchGear Promoter luciferase reporter plasmids for TMEM198
     Search ThermoFisher Antibodies for TMEM198
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM198
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TMEM198
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TMEM198
     Search LSBio for Antibodies for TMEM198
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      TMEM198 gene at Home site.
    Version: 3.12.166 28 Aug 2014
    hostname: 356980-web2.xennexinc.com index build: 126 solr: 1.4