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Aliases for TMEM194B Gene

Aliases for TMEM194B Gene

  • Transmembrane Protein 194B 2 3

External Ids for TMEM194B Gene

Previous GeneCards Identifiers for TMEM194B Gene

  • GC02U901152
  • GC02M191090
  • GC02M191369
  • GC02M183231

Summaries for TMEM194B Gene

GeneCards Summary for TMEM194B Gene

TMEM194B (Transmembrane Protein 194B) is a Protein Coding gene. An important paralog of this gene is TMEM194A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM194B Gene

Genomics for TMEM194B Gene

Regulatory Elements for TMEM194B Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for TMEM194B Gene

190,504,342 bp from pter
190,534,742 bp from pter
30,401 bases
Minus strand

Genomic View for TMEM194B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMEM194B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM194B Gene

Proteins for TMEM194B Gene

  • Protein details for TMEM194B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Transmembrane protein 194B
    Protein Accession:
    Secondary Accessions:
    • B4DYG6

    Protein attributes for TMEM194B Gene

    417 amino acids
    Molecular mass:
    48664 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for TMEM194B Gene


neXtProt entry for TMEM194B Gene

Proteomics data for TMEM194B Gene at MOPED

Post-translational modifications for TMEM194B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TMEM194B Gene

No data available for DME Specific Peptides for TMEM194B Gene

Domains for TMEM194B Gene

Protein Domains for TMEM194B Gene


Suggested Antigen Peptide Sequences for TMEM194B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the TMEM194 family.
  • Belongs to the TMEM194 family.
genes like me logo Genes that share domains with TMEM194B: view

No data available for Gene Families for TMEM194B Gene

Function for TMEM194B Gene

Phenotypes for TMEM194B Gene

GenomeRNAi human phenotypes for TMEM194B:
genes like me logo Genes that share phenotypes with TMEM194B: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TMEM194B Gene

Localization for TMEM194B Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM194B Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for TMEM194B Gene COMPARTMENTS Subcellular localization image for TMEM194B gene
Compartment Confidence
plasma membrane 3

Gene Ontology (GO) - Cellular Components for TMEM194B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM194B: view

Pathways for TMEM194B Gene

SuperPathways for TMEM194B Gene

No Data Available

Interacting Proteins for TMEM194B Gene

Gene Ontology (GO) - Biological Process for TMEM194B Gene


No data available for Pathways by source for TMEM194B Gene

Transcripts for TMEM194B Gene

mRNA/cDNA for TMEM194B Gene

(8) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(6) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TMEM194B Gene

Transmembrane protein 194B:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM194B Gene

ExUns: 1 ^ 2a · 2b · 2c ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b · 8c
SP1: - - - - -
SP2: -
SP4: -

Relevant External Links for TMEM194B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TMEM194B Gene

mRNA expression in normal human tissues for TMEM194B Gene

Protein differential expression in normal tissues for TMEM194B Gene

This gene is overexpressed in Adrenal (46.0) and Peripheral blood mononuclear cells (16.5).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for TMEM194B Gene

SOURCE GeneReport for Unigene cluster for TMEM194B Gene Hs.659824

genes like me logo Genes that share expressions with TMEM194B: view

Expression partners for TMEM194B Gene

* - Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for TMEM194B Gene

Orthologs for TMEM194B Gene

This gene was present in the common ancestor of animals.

Orthologs for TMEM194B Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia TMEM194B 35
  • 80.75 (n)
  • 72.77 (a)
TMEM194B 36
  • 68 (a)
(Canis familiaris)
Mammalia TMEM194B 35
  • 80 (n)
  • 74.03 (a)
TMEM194B 36
  • 61 (a)
(Mus musculus)
Mammalia Tmem194b 35
  • 80.67 (n)
  • 71.65 (a)
Tmem194b 16
Tmem194b 36
  • 69 (a)
(Pan troglodytes)
Mammalia TMEM194B 35
  • 99.12 (n)
  • 98.8 (a)
TMEM194B 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Tmem194b 35
  • 79.64 (n)
  • 70.62 (a)
(Monodelphis domestica)
Mammalia TMEM194B 36
  • 55 (a)
(Gallus gallus)
Aves TMEM194B 35
  • 59.55 (n)
  • 47.09 (a)
TMEM194B 36
  • 41 (a)
(Anolis carolinensis)
Reptilia TMEM194B 36
  • 44 (a)
(Danio rerio)
Actinopterygii tmem194b 35
  • 48.09 (n)
  • 34.64 (a)
tmem194b 36
  • 28 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG9723 36
  • 19 (a)
(Caenorhabditis elegans)
Secernentea F10C5.2 36
  • 17 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 20 (a)
Species with no ortholog for TMEM194B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for TMEM194B Gene

Gene Tree for TMEM194B (if available)
Gene Tree for TMEM194B (if available)

Paralogs for TMEM194B Gene

Paralogs for TMEM194B Gene

(1) SIMAP similar genes for TMEM194B Gene using alignment to 5 proteins: Pseudogenes for TMEM194B Gene

genes like me logo Genes that share paralogs with TMEM194B: view

Variants for TMEM194B Gene

Sequence variations from dbSNP and Humsavar for TMEM194B Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs8962 -- 190,506,923(+) TGGTC(A/G)TTTAA utr-variant-3-prime
rs3811610 -- 190,508,993(+) CAGTA(C/T)AATAA utr-variant-3-prime
rs4073872 -- 190,529,608(+) CTCCA(G/T)GAAGT intron-variant
rs4073873 -- 190,529,857(+) TGCCA(C/T)CCCAT intron-variant
rs4076122 -- 190,530,201(-) AGGCA(C/T)GAACA intron-variant

Relevant External Links for TMEM194B Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for TMEM194B Gene

Disorders for TMEM194B Gene

(1) University of Copenhagen DISEASES for TMEM194B Gene

genes like me logo Genes that share disorders with TMEM194B: view

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , Novoseek inferred disease relationships , Genatlas and External Links for TMEM194B Gene

Publications for TMEM194B Gene

  1. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 3 4
  2. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PMID: 21139048) Danielsen J.M. … Nielsen M.L. (Mol. Cell Proteomics 2011) 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4
  4. The sequence of the human genome. (PMID: 11181995) Venter J.C. … Zhu X. (Science 2001) 3

Products for TMEM194B Gene

Sources for TMEM194B Gene

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