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Aliases for TMEM194A Gene

Aliases for TMEM194A Gene

  • Transmembrane Protein 194A 2 3
  • Transmembrane Protein 194 2 3
  • TMEM194 3 4
  • KIAA0286 4

External Ids for TMEM194A Gene

Previous Symbols for TMEM194A Gene

  • TMEM194

Summaries for TMEM194A Gene

GeneCards Summary for TMEM194A Gene

TMEM194A (Transmembrane Protein 194A) is a Protein Coding gene. An important paralog of this gene is TMEM194B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TMEM194A Gene

Genomics for TMEM194A Gene

Genomic Location for TMEM194A Gene

57,055,643 bp from pter
57,088,063 bp from pter
32,421 bases
Minus strand

Genomic View for TMEM194A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TMEM194A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TMEM194A Gene

Regulatory Elements for TMEM194A Gene

Proteins for TMEM194A Gene

  • Protein details for TMEM194A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Transmembrane protein 194A
    Protein Accession:
    Secondary Accessions:
    • Q17R72
    • Q68DH0
    • Q6IQ25

    Protein attributes for TMEM194A Gene

    444 amino acids
    Molecular mass:
    50640 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAH71597.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAA22955.2; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for TMEM194A Gene


neXtProt entry for TMEM194A Gene

Proteomics data for TMEM194A Gene at MOPED

Post-translational modifications for TMEM194A Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys75 and Lys375
  • Glycosylation at Asn125

Other Protein References for TMEM194A Gene

No data available for DME Specific Peptides for TMEM194A Gene

Domains for TMEM194A Gene

Protein Domains for TMEM194A Gene



  • Belongs to the TMEM194 family.:
    • O14524
genes like me logo Genes that share domains with TMEM194A: view

No data available for Gene Families for TMEM194A Gene

Function for TMEM194A Gene

Gene Ontology (GO) - Molecular Function for TMEM194A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
genes like me logo Genes that share ontologies with TMEM194A: view

miRNA for TMEM194A Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for TMEM194A Gene

Localization for TMEM194A Gene

Subcellular locations from UniProtKB/Swiss-Prot for TMEM194A Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for TMEM194A Gene COMPARTMENTS Subcellular localization image for TMEM194A gene
Compartment Confidence
plasma membrane 2
nucleus 1

Gene Ontology (GO) - Cellular Components for TMEM194A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TMEM194A: view

Pathways for TMEM194A Gene

SuperPathways for TMEM194A Gene

No Data Available

Interacting Proteins for TMEM194A Gene

Gene Ontology (GO) - Biological Process for TMEM194A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with TMEM194A: view

No data available for Pathways by source for TMEM194A Gene

Transcripts for TMEM194A Gene

Unigene Clusters for TMEM194A Gene

Transmembrane protein 194A:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TMEM194A Gene

No ASD Table

Relevant External Links for TMEM194A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TMEM194A Gene

mRNA expression in normal human tissues for TMEM194A Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for TMEM194A Gene

SOURCE GeneReport for Unigene cluster for TMEM194A Gene Hs.591040

genes like me logo Genes that share expressions with TMEM194A: view

Orthologs for TMEM194A Gene

This gene was present in the common ancestor of animals.

Orthologs for TMEM194A Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia TMEM194A 36
  • 99.77 (n)
  • 99.55 (a)
TMEM194A 37
  • 100 (a)
(Bos Taurus)
Mammalia TMEM194A 36
  • 89.41 (n)
  • 85.59 (a)
TMEM194A 37
  • 86 (a)
(Canis familiaris)
Mammalia TMEM194A 36
  • 91.48 (n)
  • 88.58 (a)
TMEM194A 37
  • 81 (a)
(Mus musculus)
Mammalia Tmem194 36
  • 85.4 (n)
  • 82.57 (a)
Tmem194 16
Tmem194 37
  • 82 (a)
(Monodelphis domestica)
Mammalia TMEM194A 37
  • 77 (a)
(Ornithorhynchus anatinus)
Mammalia TMEM194A 37
  • 45 (a)
(Rattus norvegicus)
Mammalia Tmem194 36
  • 84.55 (n)
  • 82.88 (a)
(Gallus gallus)
Aves TMEM194A 36
  • 65.84 (n)
  • 63.95 (a)
TMEM194A 37
  • 60 (a)
(Anolis carolinensis)
Reptilia TMEM194A 37
  • 60 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.3173 36
tmem194a 36
  • 65.81 (n)
  • 64.62 (a)
(Danio rerio)
Actinopterygii tmem194a 36
  • 59.98 (n)
  • 54.76 (a)
tmem194a 37
  • 47 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG9723 37
  • 22 (a)
(Caenorhabditis elegans)
Secernentea F10C5.2 37
  • 19 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 28 (a)
Species with no ortholog for TMEM194A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for TMEM194A Gene

Gene Tree for TMEM194A (if available)
Gene Tree for TMEM194A (if available)

Paralogs for TMEM194A Gene

Paralogs for TMEM194A Gene

Selected SIMAP similar genes for TMEM194A Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with TMEM194A: view

Variants for TMEM194A Gene

Sequence variations from dbSNP and Humsavar for TMEM194A Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type MAF
rs4039 -- 57,055,827(+) AATAT(G/T)TAAAT utr-variant-3-prime
rs364408 -- 57,070,578(+) GGAGC(G/T)GTCTT intron-variant
rs371240 -- 57,069,423(-) TAGGG(G/T)GGCTG intron-variant
rs379367 -- 57,069,424(+) AGCCC(A/C)CCTAA intron-variant
rs387513 -- 57,069,441(+) TTTAA(A/T)TTTCA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TMEM194A Gene

Variant ID Type Subtype PubMed ID
nsv832428 CNV Gain 17160897
nsv899110 CNV Loss 21882294
nsv899111 CNV Loss 21882294

Relevant External Links for TMEM194A Gene

HapMap Linkage Disequilibrium report

Disorders for TMEM194A Gene

No disorders were found for TMEM194A Gene.

No data available for UniProtKB/Swiss-Prot for TMEM194A Gene

Publications for TMEM194A Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. Construction and characterization of human brain cDNA libraries suitable for analysis of cDNA clones encoding relatively large proteins. (PMID: 9179496) Ohara O. … Nomura N. (DNA Res. 1997) 3 4
  3. Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PMID: 12168954) Nakajima D. … Nagase T. (DNA Res. 2002) 3 4
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3

Products for TMEM194A Gene

Sources for TMEM194A Gene

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