Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



TMEM192 Gene

protein-coding   GIFtS: 39
GCID: GC04M165997

Transmembrane Protein 192

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Transmembrane Protein 1921 2

External Ids:    HGNC: 267751   Entrez Gene: 2019312   Ensembl: ENSG000001700887   UniProtKB: Q8IY953   

Export aliases for TMEM192 gene to outside databases

Previous GC identifers: GC04M166219 GC04M161750


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for TMEM192 Gene:
TMEM192 (transmembrane protein 192) is a protein-coding gene. Diseases associated with TMEM192 include tonsillitis, and thyroiditis.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
Regulatory elements:
   Regulatory transcription factor binding sites in the TMEM192 gene promoter:
         HSF2   FOXO4   HSF1short   HSF1 (long)   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for TMEM192

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TMEM192


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q32.3   Ensembl cytogenetic band:  4q32.3   HGNC cytogenetic band: 4q32.3

TMEM192 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TMEM192 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04M165997:  view genomic region     (about GC identifiers)

Start:
165,995,574 bp from pter      End:
166,129,701 bp from pter
Size:
134,128 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: TM192_HUMAN, Q8IY95 (See protein sequence)
Recommended Name: Transmembrane protein 192  
Size: 271 amino acids; 30922 Da
Subunit: Homodimer (Probable)
Sequence caution: Sequence=CAD97974.1; Type=Erroneous initiation;
Secondary accessions: Q7Z3A1 Q8N928
Alternative splicing: 2 isoforms:  Q8IY95-1   Q8IY95-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TMEM192: NX_Q8IY95

Explore proteomics data for TMEM192 at MOPED

Post-translational modifications: 

  • Not N-glycosylated1
  • Ubiquitination2 at Lys254
  • Modification sites at PhosphoSitePlus

  • See TMEM192 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_001093859.1  
    ENSEMBL proteins: 
     ENSP00000305069   ENSP00000425335   ENSP00000424590  

    TMEM192 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for TMEM192
    OriGene Custom MassSpec
    OriGene Custom Protein Services for TMEM192
    GenScript Custom Purified and Recombinant Proteins Services for TMEM192
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TMEM192

    TMEM192 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    OriGene Antibodies for TMEM192
    OriGene Custom Antibody Services for TMEM192
    Novus Biologicals TMEM192 Antibodies
    Abcam antibodies for TMEM192
    Cloud-Clone Corp. Antibodies for TMEM192
    ThermoFisher Antibodies for TMEM192
    LSBio Antibodies in human, mouse, rat for TMEM192

    TMEM192 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for TMEM192
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for TMEM192
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for TMEM192
    Cloud-Clone Corp. CLIAs for TMEM192


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus

    ProtoNet protein and cluster: Q8IY95

    UniProtKB/Swiss-Prot: TM192_HUMAN, Q8IY95
    Similarity: Belongs to the TMEM192 family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0042803protein homodimerization activity IDA--
         
    TMEM192 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TMEM192
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TMEM192

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TMEM192
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TMEM192

    miRNA
    Products:
        
    miRTarBase miRNAs that target TMEM192:
    hsa-mir-181a-5p (MIRT047317), hsa-mir-101-3p (MIRT027253), hsa-mir-30a-5p (MIRT028454)

    Block miRNA regulation of human, mouse, rat TMEM192 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TMEM192 (see all 16):
    hsa-miR-30c hsa-miR-502-5p hsa-miR-4263 hsa-miR-30d hsa-miR-545 hsa-miR-3918 hsa-miR-621 hsa-miR-153
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for TMEM192
    Predesigned siRNA for gene silencing in human, mouse, rat TMEM192

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for TMEM192

    Clone
    Products:
         
    OriGene clones in human, mouse for TMEM192 (see all 8)
    OriGene ORF clones in mouse, rat for TMEM192
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TMEM192 (NM_001100389)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM192
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM192

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for TMEM192
    Browse ESI BIO Cell Lines and PureStem Progenitors for TMEM192 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM192


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    TM192_HUMAN, Q8IY95: Lysosome membrane; Multi-pass membrane protein. Late endosome
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    endosome5
    lysosome5
    vacuole5
    plasma membrane3
    cytosol2
    golgi apparatus2
    nucleus2

    Gene Ontology (GO): Selected cellular component terms (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634NOT nucleus IDA--
    GO:0005764lysosome IDA--
    GO:0005765lysosomal membrane IDA--
    GO:0005770late endosome IDA--
    GO:0005783NOT endoplasmic reticulum IDA--

    TMEM192 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TMEM192
    Interactions:

        Search GeneGlobe Interaction Network for TMEM192

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    2 Interacting proteins for TMEM192 (ENSP000003050694) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ATP6V1AENSP000002733984STRING: ENSP00000273398
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TMEM192 (TM192)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for TMEM192 gene (2 alternative transcripts): 
    NM_152681.1  NM_001100389.1  

    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000306480(uc003iqz.4) ENST00000506087 ENST00000505095
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat TMEM192 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TMEM192 (see all 16):
    hsa-miR-30c hsa-miR-502-5p hsa-miR-4263 hsa-miR-30d hsa-miR-545 hsa-miR-3918 hsa-miR-621 hsa-miR-153
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for TMEM192
    Predesigned siRNA for gene silencing in human, mouse, rat TMEM192
    Clone
    Products:
         
    OriGene clones in human, mouse for TMEM192 (see all 8)
    OriGene ORF clones in mouse, rat for TMEM192
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TMEM192 (NM_001100389)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TMEM192
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM192
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for TMEM192
    OriGene qSTAR qPCR primer pairs in human, mouse for TMEM192
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMEM192
      QuantiTect SYBR Green Assays in human, mouse, rat TMEM192
      QuantiFast Probe-based Assays in human, mouse, rat TMEM192

    Selected AceView cDNA sequences (see all 76):

    CD674718 CN484330 AI820806 AI792473 CR590819 AA367032 BG168928 H21389 
    AI650736 AI205977 BQ434739 AI205976 BQ787089 CR619656 AA346826 CB143684 
    CD172249 CA950548 AW449278 AK095801 BQ786823 AW779864 CB162517 CA950315 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    TMEM192 expression in normal human tissues (normalized intensities)      TMEM192 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    TMEM192 Expression
    About this image


    TMEM192 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 7) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Ovary (Reproductive System)
             Oviduct
     
     Pancreas (Endocrine System)
             Islets of Langerhans
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
    TMEM192 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TMEM192 Protein Expression

    UniProtKB/Swiss-Prot: TM192_HUMAN, Q8IY95
    Tissue specificity: Strongly expressed in kidney, liver, lung and pancreas

        Custom PCR Arrays for TMEM192
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for TMEM192
    OriGene qSTAR qPCR primer pairs in human, mouse for TMEM192
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMEM192
    QuantiTect SYBR Green Assays in human, mouse, rat TMEM192
    QuantiFast Probe-based Assays in human, mouse, rat TMEM192
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM192

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals.

    Orthologs for TMEM192 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tmem1921 , 5 transmembrane protein 1921, 5 82.08(n)1
    79.32(a)1
      8 (32.44 cM)5
    730671  NM_028427.31  NP_082703.11 
     649471855 
    chicken
    (Gallus gallus)
    Aves TMEM1926
    transmembrane protein 192
    65(a)
    1 ↔ 1
    4(23236487-23257108)
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    Uncharacterized protein
    70(a)
    60(a)
    many → 1
    many → 1
    5(125448959-125455871)
    GL343317.1(3882-17326)
    African clawed frog
    (Xenopus laevis)
    Amphibia CD255556.12   -- 71.39(n)    CD255556.1 
    zebrafish
    (Danio rerio)
    Actinopterygii tmem1921 transmembrane protein 192 49.14(n)
    39.92(a)
      797335  NM_001102393.1  NP_001095863.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG75236
    --
    21(a)
    1 ↔ 1
    3R(13494866-13496617)


    ENSEMBL Gene Tree for TMEM192 (if available)
    TreeFam Gene Tree for TMEM192 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for TMEM192 gene

    TMEM192 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for TMEM192
    PGOHUM00000243664


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for TMEM192 (see all 777)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1458580711,2
    --165996891(+) TGATAC/TTTGTA 1 -- int10--------
    rs68217491,2
    C,A--165996992(+) tggtaC/Ttacag 1 -- int10--------
    rs68450381,2
    C,F,A,H--165997016(+) cacccG/Aaccca 1 -- int15Minor allele frequency- A:0.04NS EA WA 534
    rs1405505921,2
    --165997110(+) TGAACA/CCGGTA 1 -- int10--------
    rs1825789181,2
    --165997113(+) ACCCGG/TTAGAA 1 -- int10--------
    rs781630181,2
    F--165997185(+) AAAAAA/CAAAAC 1 -- int12Minor allele frequency- C:0.08CSA WA 120
    rs1869071731,2
    --165997258(+) CTTTAC/TATTTT 1 -- ut310--------
    rs1504849351,2
    --165997274(+) ATTGCC/TATTTT 1 -- ut310--------
    rs575503881,2
    C,F--165997375(+) ATACCT/GATACA 1 -- ut315Minor allele frequency- G:0.44NA CSA WA EA 362
    rs1383078741,2
    --165997381(+) ATACAC/TATACA 1 -- ut310--------

    HapMap Linkage Disequilibrium report for TMEM192 (165995574 - 166129701 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for TMEM192 (see all 12):    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv820721CNV Deletion20802225
    esv1000719CNV Deletion20482838
    esv2558277CNV Deletion19546169
    esv2728686CNV Deletion23290073
    nsv507211CNV Insertion20534489
    nsv518959CNV Loss19592680
    nsv513175CNV Loss21212237
    nsv511271CNV Loss21212237
    dgv908n67CNV Loss20364138
    esv22270CNV Gain19812545

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TMEM192
    DNA2.0 Custom Variant and Variant Library Synthesis for TMEM192

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    5 diseases for TMEM192:    About MalaCards
    tonsillitis    thyroiditis    cerebritis    endotheliitis
    prostatitis


    TMEM192 for disorders           About GeneDecksing


    Export disorders for TMEM192 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for TMEM192 gene, integrated from 10 sources (see all 19):
    (articles sorted by number of sources associating them with TMEM192)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular characterisation of 'transmembrane protein 192' (TMEM192), a novel protein of the lysosomal membrane. (PubMed id 20370317)1, 2 Schroder B.... Saftig P. (Biol. Chem. 2010)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    4. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    5. Global landscape of HIV-human protein complexes. (PubMed id 22190034)1 JAoger S....Krogan N.J. (Nature 2012)
    6. Lysosomal membrane protein TMEM192 deficiency triggers crosstalk between autophagy and apoptosis in HepG2 hepatoma cells. (PubMed id 22736246)1 Liu Z....Hu L.K. (Oncol. Rep. 2012)
    7. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    8. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    9. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    10. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 201931 HGNC: 26775 AceView: FLJ38482 Ensembl:ENSG00000170088 euGenes: HUgn201931
    ECgene: TMEM192 H-InvDB: TMEM192

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for TMEM192 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for TMEM192 gene:
    Search GeneIP for patents involving TMEM192

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for TMEM192   OriGene RNAi products in human, mouse, rat for TMEM192  
     OriGene qPCR primer pairs and template standards for TMEM192   OriGene Protein Over-expression Lysate for TMEM192  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for TMEM192  
     OriGene qSTAR qPCR primer pairs in human, mouse for TMEM192   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for TMEM192   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for TMEM192   OriGene Custom Protein Services for TMEM192  

     
     
     Block miRNA regulation of human, mouse, rat TMEM192 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing TMEM192
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TMEM192 Predesigned siRNA for gene silencing in human, mouse, rat TMEM192
     QuantiFast Probe-based Assays in human, mouse, rat TMEM192 QuantiTect SYBR Green Assays in human, mouse, rat TMEM192
     Custom PCR Arrays for TMEM192 Search Chromatin IP Primers for TMEM192
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TMEM192  Search GeneGlobe Interaction Network for TMEM192
     Regulatory tfbs in TMEM192 promoter
     GenScript Custom Purified and Recombinant Proteins Services for TMEM192 GenScript cDNA clones with any tag delivered in your preferred vector for TMEM192
     GenScript Custom Assay Services for TMEM192 GenScript Custom overexpressing Cell Line Services for TMEM192
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for TMEM192 (TM192)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     TMEM192 antibodies
     Antibodies for TMEM192
     See all of Abcam's Antibodies, Kits and Proteins for TMEM192
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for TMEM192
     Antibodies for TMEM192
     ELISAs for TMEM192
     CLIAs for TMEM192



     Browse ESI BIO Cell Lines and PureStem Progenitors for TMEM192
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TMEM192
     Browse SwitchGear 3'UTR luciferase reporter plasmids for TMEM192
     Browse SwitchGear Promoter luciferase reporter plasmids for TMEM192
     ThermoFisher Antibodies for TMEM192
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TMEM192
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TMEM192
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TMEM192
     LSBio Antibodies in human, mouse, rat for TMEM192
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      TMEM192 gene at Home site.
    Version: 3.12.136 22 July 2014
    hostname: 356977-web1.xennexinc.com index build: 126 solr: 1.4